메뉴 건너뛰기




Volumn 60, Issue 3, 2016, Pages 1208-1215

Searching for the optimal predictor of ciprofloxacin resistance in Klebsiella pneumoniae by using in vitro dynamic models

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; ANTIINFECTIVE AGENT;

EID: 84960130126     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.02334-15     Document Type: Article
Times cited : (16)

References (36)
  • 2
    • 84886803095 scopus 로고    scopus 로고
    • Antibiotics in the clinical pipeline in 2013
    • Butler MS, Blaskovich MA, Cooper MA. 2013. Antibiotics in the clinical pipeline in 2013. J Antibiot (Tokyo) 66:571-591. http://dx.doi.org/10.1038/ja.2013.86.
    • (2013) J Antibiot (Tokyo) , vol.66 , pp. 571-591
    • Butler, M.S.1    Blaskovich, M.A.2    Cooper, M.A.3
  • 3
    • 33644510131 scopus 로고    scopus 로고
    • The role of pharmacodynamic research in the assessment and development of new antibacterial drugs
    • Lister P. 2006. The role of pharmacodynamic research in the assessment and development of new antibacterial drugs. Biochem Pharmacol 71:1057-1065. http://dx.doi.org/10.1016/j.bcp. 2005.10.038.
    • (2006) Biochem Pharmacol , vol.71 , pp. 1057-1065
    • Lister, P.1
  • 4
    • 84964296722 scopus 로고    scopus 로고
    • Applying pharmacokinetic/pharmacodynamic principles in critically ill patients: Optimizing efficacy and reducing resistance development
    • Abdul-Aziz MH, Lipman J, Mouton JW, Hope WW, Roberts JA. 2015. Applying pharmacokinetic/pharmacodynamic principles in critically ill patients: optimizing efficacy and reducing resistance development. Semin Respir Crit Care Med 36:136-153. http://dx.doi.org/10.1055/s-0034-1398490.
    • (2015) Semin Respir Crit Care Med , vol.36 , pp. 136-153
    • Abdul-Aziz, M.H.1    Lipman, J.2    Mouton, J.W.3    Hope, W.W.4    Roberts, J.A.5
  • 5
    • 55249097219 scopus 로고    scopus 로고
    • In vitro dynamic models as tools to predict antibiotic pharmacodynamics
    • Nightingale CH, Ambrose PG, Drusano GL, Murakawa T ed, 2nd ed, section II. Nonclinical models of infection. Informa Healthcare USA, New York, NY
    • Firsov AA, Zinner SH, Lubenko IY. 2007. In vitro dynamic models as tools to predict antibiotic pharmacodynamics, p 45-78. In Nightingale CH, Ambrose PG, Drusano GL, Murakawa T (ed), Antimicrobial pharmacodynamics in theory and clinical practice, 2nd ed, section II. Nonclinical models of infection. Informa Healthcare USA, New York, NY.
    • (2007) Antimicrobial Pharmacodynamics in Theory and Clinical Practice , pp. 45-78
    • Firsov, A.A.1    Zinner, S.H.2    Lubenko, I.Y.3
  • 6
    • 0038414586 scopus 로고    scopus 로고
    • In vitro pharmacodynamic evaluation of the mutant selection window hypothesis using four fluoroquinolones against Staphylococcus aureus
    • Firsov AA, Vostrov SN, Lubenko IY, Drlica K, Portnoy YA, Zinner SH. 2003. In vitro pharmacodynamic evaluation of the mutant selection window hypothesis using four fluoroquinolones against Staphylococcus aureus. Antimicrob Agents Chemother 47:1604-1613. http://dx.doi.org/10.1128/AAC.47.5.1604-1613.2003.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 1604-1613
    • Firsov, A.A.1    Vostrov, S.N.2    Lubenko, I.Y.3    Drlica, K.4    Portnoy, Y.A.5    Zinner, S.H.6
  • 7
    • 3543064070 scopus 로고    scopus 로고
    • ABT492 and levofloxacin: Comparison of their pharmacodynamics and their abilities to prevent selection of resistant Staphylococcus aureus in an in vitro dynamic model
    • Firsov AA, Vostrov SN, Lubenko IY, Arzamastsev AP, Portnoy YA, Zinner SH. 2004. ABT492 and levofloxacin: comparison of their pharmacodynamics and their abilities to prevent selection of resistant Staphylococcus aureus in an in vitro dynamic model. J Antimicrob Chemother 54:178-186. http://dx.doi.org/10.1093/jac/dkh242.
    • (2004) J Antimicrob Chemother , vol.54 , pp. 178-186
    • Firsov, A.A.1    Vostrov, S.N.2    Lubenko, I.Y.3    Arzamastsev, A.P.4    Portnoy, Y.A.5    Zinner, S.H.6
  • 8
    • 55249124957 scopus 로고    scopus 로고
    • Enrichment of resistant Staphylococcus aureus at ciprofloxacin concentrations simulated within the mutant selection window: Bolus versus continuous infusion
    • Firsov AA, Smirnova MV, Strukova EN, Vostrov SN, Portnoy YA, Zinner SH. 2008. Enrichment of resistant Staphylococcus aureus at ciprofloxacin concentrations simulated within the mutant selection window: bolus versus continuous infusion. Int J Antimicrob Agents 32:488-493. http://dx.doi.org/10.1016/j.ijantimicag.2008.06.031.
    • (2008) Int J Antimicrob Agents , vol.32 , pp. 488-493
    • Firsov, A.A.1    Smirnova, M.V.2    Strukova, E.N.3    Vostrov, S.N.4    Portnoy, Y.A.5    Zinner, S.H.6
  • 10
    • 84921924355 scopus 로고    scopus 로고
    • Predicting bacterial resistance using the time inside the mutant selection window: Possibilities and limitations
    • Firsov AA, Portnoy YA, Strukova EN, Shlykova DS, Zinner SH. 2014. Predicting bacterial resistance using the time inside the mutant selection window: possibilities and limitations. Int J Antimicrob Agents 44:301-305. http://dx.doi.org/10.1016/j.ijantimicag.2014.06.013.
    • (2014) Int J Antimicrob Agents , vol.44 , pp. 301-305
    • Firsov, A.A.1    Portnoy, Y.A.2    Strukova, E.N.3    Shlykova, D.S.4    Zinner, S.H.5
  • 11
    • 84940028121 scopus 로고    scopus 로고
    • Bacterial antibiotic resistance studies using in vitro dynamic models: Population analysis vs. Susceptibility testing as endpoints of mutant enrichment
    • Firsov AA, Strukova EN, Portnoy YA, Shlykova DS, Zinner SH. 2015. Bacterial antibiotic resistance studies using in vitro dynamic models: population analysis vs. susceptibility testing as endpoints of mutant enrichment. Int J Antimicrob Agents 46:313-318. http://dx.doi.org/10.1016/j.ijantimicag.2015.06.007.
    • (2015) Int J Antimicrob Agents , vol.46 , pp. 313-318
    • Firsov, A.A.1    Strukova, E.N.2    Portnoy, Y.A.3    Shlykova, D.S.4    Zinner, S.H.5
  • 12
    • 0037417014 scopus 로고    scopus 로고
    • Activities of moxifloxacin against, and emergence of resistance in, Streptococcus pneumoniae and Pseudomonas aeruginosa in an in vitro pharmacokinetic model
    • MacGowan AP, Rogers CA, Holt HA, Bowker KE. 2003. Activities of moxifloxacin against, and emergence of resistance in, Streptococcus pneumoniae and Pseudomonas aeruginosa in an in vitro pharmacokinetic model. Antimicrob Agents Chemother 47:1088-1095. http://dx.doi.org/10.1128/AAC.47.3.1088-1095.2003.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 1088-1095
    • MacGowan, A.P.1    Rogers, C.A.2    Holt, H.A.3    Bowker, K.E.4
  • 13
    • 0141894015 scopus 로고    scopus 로고
    • Emergence of resistant Streptococcus pneumoniae in an in vitro dynamic model that simulates moxifloxacin concentrations inside and outside the mutant selection window: Related changes in susceptibility, resistance frequency and bacterial killing
    • Zinner SH, Lubenko IY, Gilbert D, Simmons K, Zhao X, Drlica K, Firsov AA. 2003. Emergence of resistant Streptococcus pneumoniae in an in vitro dynamic model that simulates moxifloxacin concentrations inside and outside the mutant selection window: related changes in susceptibility, resistance frequency and bacterial killing. J Antimicrob Chemother 52:616-622. http://dx.doi.org/10.1093/jac/dkg401.
    • (2003) J Antimicrob Chemother , vol.52 , pp. 616-622
    • Zinner, S.H.1    Lubenko, I.Y.2    Gilbert, D.3    Simmons, K.4    Zhao, X.5    Drlica, K.6    Firsov, A.A.7
  • 14
    • 35448975278 scopus 로고    scopus 로고
    • Effect of GrlA mutation on the development quinolone resistance in Staphylococcus aureus in an in vitro pharmacokinetic model
    • Oonishi Y, Mitsuyama O, Yamaguchi K. 2007. Effect of GrlA mutation on the development quinolone resistance in Staphylococcus aureus in an in vitro pharmacokinetic model. J Antimicrob Chemother 60:1030-1037. http://dx.doi.org/10.1093/jac/dkm344.
    • (2007) J Antimicrob Chemother , vol.60 , pp. 1030-1037
    • Oonishi, Y.1    Mitsuyama, O.2    Yamaguchi, K.3
  • 15
    • 33846572283 scopus 로고    scopus 로고
    • The relationship between quinolone exposures and resistance amplification is characterized by an inverted U: A new paradigm for optimizing pharmacodynamics to counterselect resistance
    • Tam VH, Louie A, Deziel MR, Liu W, Leary R, Drusano GL. 2007. The relationship between quinolone exposures and resistance amplification is characterized by an inverted U: a new paradigm for optimizing pharmacodynamics to counterselect resistance. Antimicrob Agents Chemother 51:744-747. http://dx.doi.org/10.1128/AAC.00334-06.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 744-747
    • Tam, V.H.1    Louie, A.2    Deziel, M.R.3    Liu, W.4    Leary, R.5    Drusano, G.L.6
  • 16
    • 79955546427 scopus 로고    scopus 로고
    • Mutant prevention concentration-based pharmacokinetic/pharmacodynamic indices as dosing targets for suppressing the enrichment of levofloxacinresistant subpopulations of Staphylococcus aureus
    • Liang B, Bai N, Cai Y, Wang R, Drlica K, Zhao X. 2011. Mutant prevention concentration-based pharmacokinetic/pharmacodynamic indices as dosing targets for suppressing the enrichment of levofloxacinresistant subpopulations of Staphylococcus aureus. Antimicrob Agents Chemother 55:2409-2412. http://dx.doi.org/10.1128/AAC.00975-10.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 2409-2412
    • Liang, B.1    Bai, N.2    Cai, Y.3    Wang, R.4    Drlica, K.5    Zhao, X.6
  • 17
    • 80053143850 scopus 로고    scopus 로고
    • Mutantprevention concentration and mechanism of resistance in clinical isolates and enrofloxacin/marbofloxacin-selected mutants of Escherichia coli of canine origin
    • Gebru E, Choi M-J, Lee S-J, Damte D, Park SC. 2011. Mutantprevention concentration and mechanism of resistance in clinical isolates and enrofloxacin/marbofloxacin-selected mutants of Escherichia coli of canine origin. J Med Microbiol 60:1512-1522. http://dx.doi.org/10.1099/jmm.0.028654-0.
    • (2011) J Med Microbiol , vol.60 , pp. 1512-1522
    • Gebru, E.1    Choi, M.-J.2    Lee, S.-J.3    Damte, D.4    Park, S.C.5
  • 18
    • 4644224563 scopus 로고    scopus 로고
    • In vivo pharmacodynamics efficacy of gatifloxacin against Streptococcus pneumoniae in an experimental model of pneumonia: Impact of the low levels of fluoroquinolone resistance on the enrichment of resistant mutants
    • Croisier D, Etienne M, Piroth L, Bergoin E, Lequeu C, Portier H, Chavanet P. 2004. In vivo pharmacodynamics efficacy of gatifloxacin against Streptococcus pneumoniae in an experimental model of pneumonia: impact of the low levels of fluoroquinolone resistance on the enrichment of resistant mutants. J Antimicrob Chemother 54:640-647. http://dx.doi.org/10.1093/jac/dkh393.
    • (2004) J Antimicrob Chemother , vol.54 , pp. 640-647
    • Croisier, D.1    Etienne, M.2    Piroth, L.3    Bergoin, E.4    Lequeu, C.5    Portier, H.6    Chavanet, P.7
  • 19
    • 0035884924 scopus 로고    scopus 로고
    • Restricting the selection of antibiotic-resistant mutants: A general strategy derived from fluoroquinolone studies
    • Zhao X, Drlica K. 2001. Restricting the selection of antibiotic-resistant mutants: a general strategy derived from fluoroquinolone studies. Clin Infect Dis 33:147-156.
    • (2001) Clin Infect Dis , vol.33 , pp. 147-156
    • Zhao, X.1    Drlica, K.2
  • 20
    • 3843150553 scopus 로고    scopus 로고
    • The role of PK/PD parameters to avoid selection and increase of resistance: Mutant prevention concentration
    • Blondeau JM, Hansen G, Metzler K, Hedlin P. 2004. The role of PK/PD parameters to avoid selection and increase of resistance: mutant prevention concentration. J Chemother 16(Suppl 3):S1-S19.
    • (2004) J Chemother , vol.16 , pp. S1-S19
    • Blondeau, J.M.1    Hansen, G.2    Metzler, K.3    Hedlin, P.4
  • 21
    • 33748701424 scopus 로고    scopus 로고
    • Selection of ciprofloxacin resistance of Escherichia coli in an in vitro kinetic model: Relation between drug exposure and mutant prevention concentration
    • Olofsson SK, Marcusson LL, Lindgren PK, Hughes D, Cars O. 2006. Selection of ciprofloxacin resistance of Escherichia coli in an in vitro kinetic model: relation between drug exposure and mutant prevention concentration. J Antimicrob Chemother 57:1116-1121. http://dx.doi.org/10.1093/jac/dkl135.
    • (2006) J Antimicrob Chemother , vol.57 , pp. 1116-1121
    • Olofsson, S.K.1    Marcusson, L.L.2    Lindgren, P.K.3    Hughes, D.4    Cars, O.5
  • 23
    • 84921925286 scopus 로고    scopus 로고
    • In vitro resistance studies with bacteria that exhibit low mutation frequencies: Prediction of "antimutant" linezolid concentrations using a mixed inoculum containing both susceptible and resistant Staphylococcus aureus
    • Firsov AA, Golikova MV, Strukova EN, Portnoy YA, Romanov AV, Edelstein MV, Zinner SH. 2015. In vitro resistance studies with bacteria that exhibit low mutation frequencies: prediction of "antimutant" linezolid concentrations using a mixed inoculum containing both susceptible and resistant Staphylococcus aureus. Antimicrob Agents Chemother 59:1014-1019. http://dx.doi.org/10.1128/AAC.04214-14.
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 1014-1019
    • Firsov, A.A.1    Golikova, M.V.2    Strukova, E.N.3    Portnoy, Y.A.4    Romanov, A.V.5    Edelstein, M.V.6    Zinner, S.H.7
  • 25
    • 0030048692 scopus 로고    scopus 로고
    • Predictors of effect of ampicillin-sulbactam against TEM-1 beta-lactamase-producing Escherichia coli in an in vitro dynamic model: Enzyme activity versus MIC
    • Firsov AA, Saverino D, Ruble M, Gilbert D, Manzano B, Medeiros AA, Zinner SH. 1996. Predictors of effect of ampicillin-sulbactam against TEM-1 beta-lactamase-producing Escherichia coli in an in vitro dynamic model: enzyme activity versus MIC. Antimicrob Agents Chemother 40:734-738.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 734-738
    • Firsov, A.A.1    Saverino, D.2    Ruble, M.3    Gilbert, D.4    Manzano, B.5    Medeiros, A.A.6    Zinner, S.H.7
  • 26
    • 0031687472 scopus 로고    scopus 로고
    • GyrA mutations associated with fluoroquinolone resistance in eight species of Enterobacteriaceae
    • Weigel LM, Steward SD, Tenover FC. 1998. gyrA mutations associated with fluoroquinolone resistance in eight species of Enterobacteriaceae. Antimicrob Agents Chemother 42:2661-2667.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 2661-2667
    • Weigel, L.M.1    Steward, S.D.2    Tenover, F.C.3
  • 27
    • 33748687636 scopus 로고    scopus 로고
    • Pyrazinoic acid and its n-propyl ester inhibit fatty acid synthase type I in replicating tubercle bacilli
    • Zimhony O, Vilchèze C, Arai M, Welch JT, Jacobs WR, Jr. 2006. Pyrazinoic acid and its n-propyl ester inhibit fatty acid synthase type I in replicating tubercle bacilli. Antimicrob Agents Chemother 50:3179-3182. http://dx.doi.org/10.1128/AAC.00218-06.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 3179-3182
    • Zimhony, O.1    Vilchèze, C.2    Arai, M.3    Welch, J.T.4    Jacobs, W.R.5
  • 28
    • 84977932804 scopus 로고    scopus 로고
    • Low propensity for development of resistance to MCB3681, the active moiety of oxaquin (MCB3837), in grampositive bacteria with vancomycin-, linezolid-, methicillin- and/or ciprofloxacin resistances, abstr F1-1968
    • Schubert S, Dalhoff A. 2006. Low propensity for development of resistance to MCB3681, the active moiety of oxaquin (MCB3837), in grampositive bacteria with vancomycin-, linezolid-, methicillin- and/or ciprofloxacin resistances, abstr F1-1968. Abstr 46th Intersci Conf Antimicrob Agents Chemother.
    • (2006) Abstr 46th Intersci Conf Antimicrob Agents Chemother
    • Schubert, S.1    Dalhoff, A.2
  • 29
    • 0344328778 scopus 로고    scopus 로고
    • Mechanisms of quinolone resistance, p 41-67
    • Hooper DC, Rubinstein E ed, 3rd ed. ASM Press, Washington, DC
    • Hooper DC. 2003. Mechanisms of quinolone resistance, p 41-67. In Hooper DC, Rubinstein E (ed), Quinolone antimicrobial agents, 3rd ed. ASM Press, Washington, DC.
    • (2003) Quinolone Antimicrobial Agents
    • Hooper, D.C.1
  • 30
    • 0037395918 scopus 로고    scopus 로고
    • Mutations in gyrA and parC genes in nalidixic acid-resistant Escherichia coli strains from food products, humans and animals
    • Sáenz Y, Zarazaga M, Briñas L, Ruiz-Larrea F, Torres C. 2003. Mutations in gyrA and parC genes in nalidixic acid-resistant Escherichia coli strains from food products, humans and animals. J Antimicrob Chemother 51:1001-1005. http://dx.doi.org/10.1093/jac/dkg168.
    • (2003) J Antimicrob Chemother , vol.51 , pp. 1001-1005
    • Sáenz, Y.1    Zarazaga, M.2    Briñas, L.3    Ruiz-Larrea, F.4    Torres, C.5
  • 31
    • 84869032869 scopus 로고    scopus 로고
    • Global fluoroquinolone resistance epidemiology and implications for clinical use
    • Dalhoff A. 2012. Global fluoroquinolone resistance epidemiology and implications for clinical use. Interdiscip Perspect Infect Dis 2012:976273. http://dx.doi.org/10.1155/2012/976273.
    • (2012) Interdiscip Perspect Infect Dis , vol.2012 , pp. 976273
    • Dalhoff, A.1
  • 32
    • 79956293351 scopus 로고    scopus 로고
    • In vitro selection of ramR and soxR mutants overexpressing efflux systems by fluoroquinolones as well as cefoxitin in Klebsiella pneumoniae
    • Bialek-Davenet S, Marcon E, Leflon-Guibout V, Lavigne JP, Bert F, Moreau R, Nicolas-Chanoine MH. 2011. In vitro selection of ramR and soxR mutants overexpressing efflux systems by fluoroquinolones as well as cefoxitin in Klebsiella pneumoniae. Antimicrob Agents Chemother 55:2795-2802. http://dx.doi.org/10.1128/AAC.00156-11.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 2795-2802
    • Bialek-Davenet, S.1    Marcon, E.2    Leflon-Guibout, V.3    Lavigne, J.P.4    Bert, F.5    Moreau, R.6    Nicolas-Chanoine, M.H.7
  • 33
    • 0036895281 scopus 로고    scopus 로고
    • Energy-dependent accumulation of norfloxacin and porin expression in clinical isolates of Klebsiella pneumoniae and relationship to extended-spectrum beta-lactamase production
    • Martínez-Martínez L, Pascual A, Conejo MDC, García I, Joyanes P, Doménech-Sánchez A, Benedí VJ. 2002. Energy-dependent accumulation of norfloxacin and porin expression in clinical isolates of Klebsiella pneumoniae and relationship to extended-spectrum beta-lactamase production. Antimicrob Agents Chemother 46:3926-3932. http://dx.doi.org/10.1128/AAC.46.12.3926-3932.2002.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 3926-3932
    • Martínez-Martínez, L.1    Pascual, A.2    Conejo, M.D.C.3    García, I.4    Joyanes, P.5    Doménech-Sánchez, A.6    Benedí, V.J.7
  • 34
    • 79956061702 scopus 로고    scopus 로고
    • Prevalence and role of efflux pump activity in ciprofloxacin resistance in clinical isolates of Klebsiella pneumoniae
    • Aathithan S, French GL. 2011. Prevalence and role of efflux pump activity in ciprofloxacin resistance in clinical isolates of Klebsiella pneumoniae. Eur J Clin Microbiol Infect Dis 30:745-752. http://dx.doi.org/10.1007/s10096-010-1147-0.
    • (2011) Eur J Clin Microbiol Infect Dis , vol.30 , pp. 745-752
    • Aathithan, S.1    French, G.L.2
  • 35
    • 0042355374 scopus 로고    scopus 로고
    • The roles of mutations in gyrA, parC, and ompK35 in fluoroquinolone resistance in Klebsiella pneumoniae
    • Chen FJ, Lauderdale TL, Ho M, Lo HJ. 2003. The roles of mutations in gyrA, parC, and ompK35 in fluoroquinolone resistance in Klebsiella pneumoniae. Microb Drug Resist 9:265-271. http://dx.doi.org/10.1089/107662903322286472.
    • (2003) Microb Drug Resist , vol.9 , pp. 265-271
    • Chen, F.J.1    Lauderdale, T.L.2    Ho, M.3    Lo, H.J.4
  • 36
    • 12844286238 scopus 로고    scopus 로고
    • Outer membrane protein profiles of clonally related Klebsiella pneumoniae isolates that differ in cefoxitin resistance
    • Skopková-Zarnayová M, Siebor E, Rovná D, Bujdáková H, Neuwirth C. 2005. Outer membrane protein profiles of clonally related Klebsiella pneumoniae isolates that differ in cefoxitin resistance. FEMS Microbiol Lett 243:197-203. http://dx.doi.org/10.1016/j.femsle.2004.12.023.
    • (2005) FEMS Microbiol Lett , vol.243 , pp. 197-203
    • Skopková-Zarnayová, M.1    Siebor, E.2    Rovná, D.3    Bujdáková, H.4    Neuwirth, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.