Mutations in gyrA and parC genes in nalidixic acid-resistant Escherichia coli strains from food products, humans and animals

Journal of Antimicrobial Chemotherapy

Volumn 51, Issue 4, 2003, Pages 1001-1005

  Sáenz, Yolanda ^a   Zarazaga, Myriam ^a   Briñas, Laura ^a   Ruiz Larrea, Fernanda ^a   Torres, Carmen ^a  

^a UNIVERSITY OF LA RIOJA   (Spain)

Author keywords

Escherichia coli; Quinolone resistance

Indexed keywords

ALANINE; ASPARAGINE; ASPARTIC ACID; CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE IV; GLUTAMIC ACID; GLYCINE; HISTIDINE; ISOLEUCINE; LEUCINE; NALIDIXIC ACID; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SERINE; TYROSINE; VALINE;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATION; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG TARGETING; ENZYME SUBUNIT; ESCHERICHIA COLI; FECES ANALYSIS; FOOD INDUSTRY; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; HUMAN; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION;

ANIMALS; ANTI-INFECTIVE AGENTS; DNA GYRASE; DNA TOPOISOMERASE IV; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; FOOD MICROBIOLOGY; HUMANS; MUTATION; NALIDIXIC ACID;

EID: 0037395918     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/dkg168     Document Type: Article

References (10)

1. Sáenz, Y., Zarazaga, M., Briñas, L., Lantero, M., Ruiz-Larrea, F. & Torres, C. (2001). Antibiotic resistance in Escherichia coli isolates obtained from animals, foods, and humans in Spain. International Journal of Antimicrobial Agents 18, 353-8.
2. Everett, M. J., Fang Jin, Y., Ricci, V. & Piddock, L. J. V. (1996). Contributions of individual mechanisms to fluoroquinolone resistance in 36 Escherichia coli strains isolated from humans and animals. Antimicrobial Agents and Chemotherapy 40, 2380-6.
3. Piddock, L. J. V. (1999). Mechanisms of fluoroquinolone resistance: an update 1994-1998. Drugs 58, 11-8.
4. Vila, J., Ruiz, J., Goñi, P. & Jiménez de Anta, T. (1996). Detection of mutations in parC in quinolone-resistant clinical isolates of Escherichia coli. Antimicrobial Agents and Chemotherapy 40, 491-3.
5. Heisig, P. (1996). Genetic evidence for a role of parC mutations in development of high-level fluoroquinolone resistance in Escherichia coli. Antimicrobial Agents and Chemotherapy 40, 879-85.
6. Oram, M. & Fisher, L. M. (1991). 4-Quinolone resistance mutations in the DNA gyrase of Escherichia coli clinical isolates identified by using the polymerase chain reaction. Antimicrobial Agents and Chemotherapy 35, 387-9.
7. Giraud, E., Leroy-Sétrin, S., Flaujac, G., Cloeckaert, A., Dho-Moulin, M. & Chaslus-Dancla, E. (2001). Characterization of high-level fluoroquinolone resistance in Escherichia coli O78:K80 isolated from turkeys. Journal of Antimicrobial Chemotherapy 47, 341-3.
8. Kern, W. V., Oethinger, M., Jellen-Ritter, A. S. & Levy, S. B. (2000). Non-target gene mutations in the development of fluoroquinolone resistance in Escherichia coli. Antimicrobial Agents and Chemotherapy 44, 814-20.
9. Vila, J., Ruiz, J., Marco, F., Barcelo, A., Goñi, P., Giralt, E. et al. (1994). Association between double mutation in gyrA gene of ciprofloxacin-resistant clinical isolates of Escherichia coli and MICs. Antimicrobial Agents and Chemotherapy 38, 2477-9.
10. Tavio, M. D., Vila, J., Ruiz, J., Martín-Sánchez, A. M. & de Anta, M. T. J. (1999). Mechanisms involved in the development of resistance to fluoroquinolones in Escherichia coli isolates. Journal of Antimicrobial Chemotherapy 44, 735-42.