Magnetically-responsive hydrogels for modulation of chondrogenic commitment of human adipose-derived stem cells

Polymers

Volumn 8, Issue 2, 2016, Pages

  Popa, Elena G ^a   Santo, Vítor E ^a   Rodrigues, Márcia T ^a   Gomes, Manuela E ^a  

^a UNIVERSITY OF MINHO   (Portugal)

Author keywords

Cartilage; Chondrogenic commitment; Magnetic nanoparticles; Magnetic tissue engineering; Stem cells; Sulfated polysaccharides

Indexed keywords

CARTILAGE; CELL ENGINEERING; CELLS; CYTOLOGY; DIAGNOSIS; GENE EXPRESSION; MAGNETISM; METABOLISM; NANOMAGNETICS; NANOPARTICLES; REMOTE CONTROL; STEM CELLS; TISSUE; TISSUE ENGINEERING;

CHONDROGENIC; CHONDROGENIC PHENOTYPES; GENE EXPRESSION LEVELS; HUMAN ADIPOSE DERIVED STEM CELLS; HUMAN ADIPOSE DERIVED STEM CELLS (HASCS); MAGNETIC NANO-PARTICLES; MAGNETIC NANOPARTI CLES (MNPS); SULFATED POLYSACCHARIDES;

HYDROGELS;

EID: 84960099061     PISSN: None     EISSN: 20734360     Source Type: Journal    
DOI: 10.3390/polym8020028     Document Type: Article

References (49)

1. Shubayev, V.I.; Pisanic Ii, T.R.; Jin, S. Magnetic nanoparticles for theragnostics. Adv. Drug Deliv. Rev. 2009, 61, 467-477.
2. Lu, A.-H.; Salabas, E.L.; Schüth, F. Magnetic nanoparticles: Synthesis, protection, functionalization, and application. Angew. Chem. Int. Ed. 2007, 46, 1222-1244.
3. Estelrich, J.; Escribano, E.; Queralt, J.; Busquets, M.A. Iron oxide nanoparticles for magnetically-guided and magnetically-responsive drug delivery. Int. J. Mol. Sci. 2015, 16, 8070-8101.
4. Arruebo, M.; Fernández-Pacheco, R.; Ibarra, M.R.; Santamaría, J. Magnetic nanoparticles for drug delivery. Nano Today 2007, 2, 22-32.
5. Amirfazli, A. Nanomedicine: Magnetic nanoparticles hit the target. Nat. Nanotechnol. 2007, 2, 467-468.
6. Akbarzadeh, A.; Samiei, M.; Davaran, S. Magnetic nanoparticles: Preparation, physical properties, and applications in biomedicine. Nanoscale Res. Lett. 2012, 7, 1-13.
7. Bock, N.; Riminucci, A.; Dionigi, C.; Russo, A.; Tampieri, A.; Landi, E.; Goranov, V.A.; Marcacci, M.; Dediu, V. A novel route in bone tissue engineering: Magnetic biomimetic scaffolds. Acta Biomater. 2010, 6, 786-796.
8. Lee, K.; Silva, E.A.; Mooney, D.J. Growth factor delivery-based tissue engineering: General approaches and a review of recent developments. J. R. Soc. Interface 2011, 8, 153-170.
9. Whatley, B.R.; Li, X.; Zhang, N.; Wen, X. Magnetic-directed patterning of cell spheroids. J. Biomed. Mater. Res. A 2013, 102, 1537-1547.
10. Tran, N.; Webster, T.J. Magnetic nanoparticles: Biomedical applications and challenges. J. Mater. Chem. 2010, 20, 8760-8767.
11. Santo, V.E.; Rodrigues, M.T.; Reis, R.L.; Gomes, M.E. Contributions and future perspectives on the use of magnetic nanoparticles as diagnostic and therapeutic tools in the field of regenerative medicine. Expert Rev. Mol. Diagn. 2013, 13, 553-566.
12. Kanczler, J.M.; Sura, H.S.; Magnay, J.; Green, D.; Oreffo, R.O.; Dobson, J.P.; El Haj, A.J. Controlled differentiation of human bone marrow stromal cells using magnetic nanoparticle technology. Tissue Eng. A 2010, 16, 3241-3250.
13. Fayol, D.; Frasca, G.;le Visage, C.; Gazeau, F.; Luciani, N.; Wilhelm, C. Use of magnetic forces to promote stem cell aggregation during differentiation, and cartilage tissue modeling. Adv. Mater. 2013, 25, 2611-2616.
14. Lima, J.; Gonçalves, A.I.; Rodrigues, M.T.; Reis, R.L.; Gomes, M.E. The effect of magnetic stimulation on the osteogenic and chondrogenic differentiation of human stem cells derived from the adipose tissue (hASCs). J. Magn. Magn. Mater. 2015, 393, 526-536.
15. Sniadecki, N.J.; Anguelouch, A.; Yang, M.T.; Lamb, C.M.; Liu, Z.; Kirschner, S.B.; Liu, Y.; Reich, D.H.; Chen, C.S. Magnetic microposts as an approach to apply forces to living cells. Proc. Natl. Acad. Sci. USA 2007, 104, 14553-14558.
16. Tasoglu, S.; Yu, C.H.; Gungordu, H.I.; Guven, S.; Vural, T.; Demirci, U. Guided and magnetic self-assembly of tunable magnetoceptive gels. Nat. Commun. 2014.
17. Tampieri, A.; Landi, E.; Valentini, F.; Sandri, M.; D'Alessandro, T.; Dediu, V.; Marcacci, M. A conceptually new type of bio-hybrid scaffold for bone regeneration. Nanotechnology 2011, 22, 184-190.
18. Popa, E.G.; Gomes, M.E.; Reis, R.L. Cell delivery systems using alginate-carrageenan hydrogel beads and fibers for regenerative medicine applications. Biomacromolecules 2011, 12, 3952-3961.
19. Mihaila, S.M.; Popa, E.G.; Reis, R.L.; Marques, A.P.; Gomes, M.E. Fabrication of endothelial cell-laden carrageenan microfibers for microvascularized bone tissue engineering applications. Biomacromolecules 2014, 15, 2849-2860.
20. Santo, V.E.; Frias, A.M.; Carida, M.; Cancedda, R.; Gomes, M.E.; Mano, J.F.; Reis, R.L. Carrageenan-based hydrogels for the controlled delivery of PDGF-BB in bone tissue engineering applications. Biomacromolecules 2009, 10, 1392-1401.
21. Rocha, P.M.; Santo, V.E.; Gomes, M.E.; Reis, R.L.; Mano, J.F. Encapsulation of adipose-derived stem cells and transforming growth factor-β 1 in carrageenan-based hydrogels for cartilage tissue engineering. J. Bioact. Compat. Polym. 2011, 26, 493-507.
22. Popa, E.; Reis, R.; Gomes, M. Chondrogenic phenotype of different cells encapsulated in κ-carrageenan hydrogels for cartilage regeneration strategies. Biotechnol. Appl. Biochem. 2012, 59, 132-141.
23. Popa, E.G.; Rodrigues, M.T.; Coutinho, D.F.; Oliveira, M.B.; Mano, J.F.; Reis, R.L.; Gomes, M.E. Cryopreservation of cell laden natural origin hydrogels for cartilage regeneration strategies. Soft Matter 2013, 9, 875-885.
24. Bhattacharyya, S.; Liu, H.; Zhang, Z.; Jam, M.; Dudeja, P.K.; Michel, G.; Linhardt, R.J.; Tobacman, J.K. Carrageenan-induced innate immune response is modified by enzymes that hydrolyze distinct galactosidic bonds. J. Nutr. Biochem. 2010, 21, 906-913.
25. Popa, E.G.; Reis, R.L.; Gomes, M.E. Seaweed polysaccharide-based hydrogels used for the regeneration of articular cartilage. Crit. Rev. Biotechnol. 2014, 35, 410-424.
26. Salbach, J.; Rachner, T.D.; Rauner, M.; Hempel, U.; Anderegg, U.; Franz, S.; Simon, J.C.; Hofbauer, L.C. Regenerative potential of glycosaminoglycans for skin and bone. J. Mol. Med. 2012, 90, 625-635.
27. Popa, E.G.; Carvalho, P.P.; Dias, A.F.; Santos, T.C.; Santo, V.E.; Marques, A.P.; Viegas, C.A.; Dias, I.R.; Gomes, M.E.; Reis, R.L. Evaluation of the in vitro and in vivo biocompatibility of carrageenan-based hydrogels. J. Biomed. Mater. Res. A 2014, 102, 4087-4097.
28. Daniel-da-Silva, A.L.; Trindade, T.; Goodfellow, B.J.; Costa, B.F.; Correia, R.N.; Gil, A.M. In situ synthesis of magnetite nanoparticles in carrageenan gels. Biomacromolecules 2007, 8, 2350-2357.
29. Mahdavinia, G.R.; Etemadi, H. In situ synthesis of magnetic CaraPVA IPN nanocomposite hydrogels and controlled drug release. Mater. Sci. Eng. C 2014, 45, 250-260.
30. Salgueiro, A.M.; Daniel-da-Silva, A.L.; Fateixa, S.; Trindade, T. κ-carrageenan hydrogel nanocomposites with release behavior mediated by morphological distinct au nanofillers. Carbohydr. Polym. 2012, 91, 100-109.
31. Mahdavinia, G.R.; Etemadi, H.; Soleymani, F. Magnetic/pH-responsive beads based on caboxymethyl chitosan and κ-carrageenan and controlled drug release. Carbohydr. Polym. 2014, 128, 112-121.
32. Mitsumata, T.; Honda, A.; Kanazawa, H.; Kawai, M. Magnetically tunable elasticity for magnetic hydrogels consisting of carrageenan and carbonyl iron particles. J. Phys. Chem. B 2012, 116, 12341-12348.
33. Santo, V.E.; Duarte, A.R.C.; Popa, E.G.; Gomes, M.E.; Mano, J.F.; Reis, R.L. Enhancement of osteogenic differentiation of human adipose derived stem cells by the controlled release of platelet lysates from hybrid scaffolds produced by supercritical fluid foaming. J. Control Release 2012, 162, 19-27.
34. Santo, V.E.; Popa, E.G.; Mano, J.F.; Gomes, M.E.; Reis, R.L. Natural assembly of platelet lysate-loaded nanocarriers into enriched 3D hydrogels for cartilage regeneration. Acta Biomater. 2015, 19, 56-65.
35. Popa, E.; Caridade, S.; Mano, J.F.; Reis, R.L.; Gomes, M.E. Chondrogenic potential of injectable κ-carrageenan hydrogel with encapsulated adipose stem cells for cartilage tissue-engineering applications. J. Tissue Eng. Regen. Med. 2013, 9, 550-563.
36. Rada, T.; Reis, R.L.; Gomes, M.E. Distinct stem cells subpopulations isolated from human adipose tissue exhibit different chondrogenic and osteogenic differentiation potential. Stem Cell Rev. Rep. 2011, 7, 64-76.
37. Rada, T.; Reis, R.L.; Gomes, M.E. Novel method for the isolation of adipose stem cells (ASCs). J. Tissue Eng. Regen. Med. 2009, 3, 158-159.
38. Daniel-da-Silva, A.L.; Loio, R.; Lopes-da-Silva, J.A.; Trindade, T.; Goodfellow, B.J.; Gil, A.M. Effects of magnetite nanoparticles on the thermorheological properties of carrageenan hydrogels. J. Colloid Interface Sci. 2008, 324, 205-211.
39. Daniel-da-Silva, A.L.; Moreira, J.; Neto, R.; Estrada, A.C.; Gil, A.M.; Trindade, T. Impact of magnetic nanofillers in the swelling and release properties of κ-carrageenan hydrogel nanocomposites. Carbohydr. Polym. 2012, 87, 328-335.
40. Roeder, E.; Henrionnet, C.; Goebel, J.C.; Gambier, N.; Beuf, O.; Grenier, D.; Chen, B.; Vuissoz, P.A.; Gillet, P.; Pinzano, A. Dose-response of superparamagnetic iron oxide labeling on mesenchymal stem cells chondrogenic differentiation: A multi-scale in vitro study. PLoS ONE 2014.
41. Markides, H.; Rotherham, M.; El Haj, A.J. Biocompatibility and toxicity of magnetic nanoparticles in regenerative medicine. J. Nanomater. 2012.
42. Haudenschild, D.R.; McPherson, J.M.; Tubo, R.; Binette, F. Differential expression of multiple genes during articular chondrocyte redifferentiation. Anat. Rec. 2001, 263, 91-98.
43. Son, B.; Kim, H.D.; Kim, M.; Kim, J.A.; Lee, J.; Shin, H.; Hwang, N.S.; Park, T.H. Physical stimuli-induced chondrogenic differentiation of mesenchymal stem cells using magnetic nanoparticles. Adv. Healthc. Mater. 2015, 4, 1339-1347.
44. Fuhrer, R.; Hofmann, S.; Hild, N.; Vetsch, J.R.; Herrmann, I.K.; Grass, R.N.; Stark, W.J. Pressureless mechanical induction of stemcell differentiation is dose and frequency dependent. PLoS ONE 2013.
45. Amin, H.D.; Brady, M.A.; St-Pierre, J.P.; Stevens, M.M.; Overby, D.R.; Ethier, C.R. Stimulation of chondrogenic differentiation of adult human bone marrow-derived stromal cells by a moderate-strength static magnetic field. Tissue Eng. A 2014, 20, 1612-1620.
46. Akiyama, H.; Lefebvre, V. Unraveling the transcriptional regulatory machinery in chondrogenesis. J. Bone Miner. Metab. 2011, 29, 390-395.
47. Goldring, M.B.; Tsuchimochi, K.; Ijiri, K. The control of chondrogenesis. J. Cell. Biochem. 2006, 97, 33-44.
48. Kasten, A.; Muller, P.; Bulnheim, U.; Groll, J.; Bruellhoff, K.; Beck, U.; Steinhoff, G.; Moller, M.; Rychly, J. Mechanical integrin stress and magnetic forces induce biological responses in mesenchymal stem cells which depend on environmental factors. J. Cell. Biochem. 2010, 111, 1586-1597.
49. Xu, F.; Wu, C.A.; Rengarajan, V.; Finley, T.D.; Keles, H.O.; Sung, Y.; Li, B.; Gurkan, U.A.; Demirci, U. Three-dimensional magnetic assembly of microscale hydrogels. Adv. Mater. 2011, 23, 4254-4260.