A structural snapshot of the rhodopsin-arrestin complex

FEBS Journal

Volumn 283, Issue 5, 2016, Pages 816-821

  Kang, Yanyong ^a   Gao, Xiang ^a   Zhou, X Edward ^a,b   He, Yuanzheng ^a   Melcher, Karsten ^a,b   Xu, H Eric ^a,b  

^a VAN ANDEL RESEARCH INSTITUTE   (United States)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

arrestin; biased signalling; G protein; G protein coupled receptors; Rhodopsin

Indexed keywords

RETINA S ANTIGEN; RHODOPSIN; BETA 2 ADRENERGIC RECEPTOR; G PROTEIN COUPLED RECEPTOR; LIGAND; LIPID BILAYER; PROTEIN BINDING;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; CRYSTALLIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; CHEMISTRY; HUMAN; LIPID BILAYER; METABOLISM; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ARRESTINS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; HUMANS; LIGANDS; LIPID BILAYERS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, G-PROTEIN-COUPLED; RHODOPSIN; SIGNAL TRANSDUCTION;

EID: 84960078752     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.13561     Document Type: Article

References (20)

1. Bjarnadottir TK, Gloriam DE, Hellstrand SH, Kristiansson H, Fredriksson R, &, Schioth HB, (2006) Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse. Genomics 88, 263-273.
2. Penela P, Ribas C, &, Mayor F Jr, (2003) Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases. Cell Signal 15, 973-981.
3. Wilden U, Hall SW, &, Kuhn H, (1986) Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments. Proc Natl Acad Sci U S A 83, 1174-1178.
4. Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, et al,. (2011) Crystal structure of the beta2 adrenergic receptor-Gs protein complex. Nature 477, 549-555.
5. Palczewski K, Kumasaka T, Hori T, Behnke CA, Motoshima H, Fox BA, Le Trong I, Teller DC, Okada T, Stenkamp RE, et al,. (2000) Crystal structure of rhodopsin: a G protein-coupled receptor. Science 289, 739-745.
6. Park JH, Scheerer P, Hofmann KP, Choe HW, &, Ernst OP, (2008) Crystal structure of the ligand-free G-protein-coupled receptor opsin. Nature 454, 183-187.
7. Choe HW, Kim YJ, Park JH, Morizumi T, Pai EF, Krauss N, Hofmann KP, Scheerer P, &, Ernst OP, (2011) Crystal structure of metarhodopsin II. Nature 471, 651-655.
8. Hirsch JA, Schubert C, Gurevich VV, &, Sigler PB, (1999) The 2.8 A crystal structure of visual arrestin: a model for arrestin's regulation. Cell 97, 257-269.
9. Kim YJ, Hofmann KP, Ernst OP, Scheerer P, Choe HW, &, Sommer ME, (2013) Crystal structure of pre-activated arrestin p44. Nature 497, 142-146.
10. Shukla AK, Westfield GH, Xiao K, Reis RI, Huang LY, Tripathi-Shukla P, Qian J, Li S, Blanc A, Oleskie AN, et al,. (2014) Visualization of arrestin recruitment by a G-protein-coupled receptor. Nature 512, 218-222.
11. Soon FF, Ng LM, Zhou XE, West GM, Kovach A, Tan MH, Suino-Powell KM, He Y, Xu Y, Chalmers MJ, et al,. (2012) Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases. Science 335, 85-88.
12. Boutet S, Lomb L, Williams GJ, Barends TR, Aquila A, Doak RB, Weierstall U, DePonte DP, Steinbrener J, Shoeman RL, et al,. (2012) High-resolution protein structure determination by serial femtosecond crystallography. Science 337, 362-364.
13. Liu W, Wacker D, Wang C, Abola E, &, Cherezov V, (2014) Femtosecond crystallography of membrane proteins in the lipidic cubic phase. Philos Trans R Soc Lond B Biol Sci 369, 20130314.
14. White TA, Barty A, Stellato F, Holton JM, Kirian RA, Zatsepin NA, &, Chapman HN, (2013) Crystallographic data processing for free-electron laser sources. Acta Crystallogr D Biol Crystallogr 69, 1231-1240.
15. Fotiadis D, Jastrzebska B, Philippsen A, Muller DJ, Palczewski K, &, Engel A, (2006) Structure of the rhodopsin dimer: a working model for G-protein-coupled receptors. Curr Opin Struct Biol 16, 252-259.
16. Standfuss J, Edwards PC, D'Antona A, Fransen M, Xie G, Oprian DD, &, Schertler GF, (2011) The structural basis of agonist-induced activation in constitutively active rhodopsin. Nature 471, 656-660.
17. Zhou XE, Melcher K, &, Xu HE, (2012) Structure and activation of rhodopsin. Acta Pharmacol Sin 33, 291-299.
18. Vishnivetskiy SA, Paz CL, Schubert C, Hirsch JA, Sigler PB, &, Gurevich VV, (1999) How does arrestin respond to the phosphorylated state of rhodopsin? J Biol Chem 274, 11451-11454.
19. Shukla AK, Manglik A, Kruse AC, Xiao K, Reis RI, Tseng WC, Staus DP, Hilger D, Uysal S, Huang LY, et al,. (2013) Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide. Nature 497, 137-141.
20. Milano SK, Kim YM, Stefano FP, Benovic JL, &, Brenner C, (2006) Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding. J Biol Chem 281, 9812-9823.