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Volumn 30, Issue 1, 2016, Pages 59-77

Neuroendocrine tumor biomarkers: From monoanalytes to transcripts and algorithms

Author keywords

biomarker; carcinoid; chromogranin A; circulating tumor cells (CTC); miRNA; monoanalyte; multianalyte; NETest; neuroendocrine tumor; PCR

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; BIOLOGICAL MARKER; CHROMOGRANIN; CHROMOGRANIN A; CHROMOGRANIN B; CONNECTIVE TISSUE GROWTH FACTOR; INSULIN; MICRORNA; NEURON SPECIFIC ENOLASE; PANCREAS POLYPEPTIDE; PANCREASTATIN; PROGASTRIN RELEASING PEPTIDE; SECRETOGRANIN II; SEROTONIN; TACHYKININ; TUMOR MARKER;

EID: 84959890838     PISSN: 1521690X     EISSN: 15321908     Source Type: Journal    
DOI: 10.1016/j.beem.2016.01.002     Document Type: Review
Times cited : (76)

References (100)
  • 1
    • 84856544369 scopus 로고    scopus 로고
    • Translational genomics: The challenge of developing cancer biomarkers
    • J.D. Brooks Translational genomics: the challenge of developing cancer biomarkers Genome Res 22 2012 183 187
    • (2012) Genome Res , vol.22 , pp. 183-187
    • Brooks, J.D.1
  • 2
    • 84905994529 scopus 로고    scopus 로고
    • A multianalyte PCR blood test outperforms single analyte elisas for neuroendocrine tumor detection
    • I. Modlin, I. Drozdov, D. Alaimo, and et al. A multianalyte pcr blood test outperforms single analyte elisas for neuroendocrine tumor detection Endocr Relat Cancer 21 2014 615 628
    • (2014) Endocr Relat Cancer , vol.21 , pp. 615-628
    • Modlin, I.1    Drozdov, I.2    Alaimo, D.3
  • 3
    • 84877727939 scopus 로고    scopus 로고
    • The identification of gut neuroendocrine tumor disease by multiple synchronous transcript analysis in blood
    • I. Modlin, I. Drozdov, and M. Kidd The identification of gut neuroendocrine tumor disease by multiple synchronous transcript analysis in blood PLoS One 2013 e63364
    • (2013) PLoS One , pp. e63364
    • Modlin, I.1    Drozdov, I.2    Kidd, M.3
  • 4
    • 84896130878 scopus 로고    scopus 로고
    • Gut neuroendocrine tumor blood qpcr fingerprint assay: Characteristics and reproducibility
    • I. Modlin, I. Drozdov, and M. Kidd Gut neuroendocrine tumor blood qpcr fingerprint assay: characteristics and reproducibility Clin Chem 52 2014 419 429
    • (2014) Clin Chem , vol.52 , pp. 419-429
    • Modlin, I.1    Drozdov, I.2    Kidd, M.3
  • 5
    • 79251478039 scopus 로고    scopus 로고
    • Genomics and the continuum of cancer care
    • doi:310.1056/NEJMra0907178
    • U. McDermott, J.R. Downing, and M.R. Stratton Genomics and the continuum of cancer care N Engl J Med 364 2011 340 350 doi:310.1056/NEJMra0907178
    • (2011) N Engl J Med , vol.364 , pp. 340-350
    • McDermott, U.1    Downing, J.R.2    Stratton, M.R.3
  • 6
    • 84926422042 scopus 로고    scopus 로고
    • The status of neuroendocrine tumor imaging: From darkness to light?
    • L. Bodei, A. Sundin, M. Kidd, and et al. The status of neuroendocrine tumor imaging: from darkness to light? Neuroendocrinology 101 2015 1 17
    • (2015) Neuroendocrinology , vol.101 , pp. 1-17
    • Bodei, L.1    Sundin, A.2    Kidd, M.3
  • 7
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Epub 2004 Apr 1429
    • J.G. Paez, P.A. Janne, J.C. Lee, and et al. Egfr mutations in lung cancer: correlation with clinical response to gefitinib therapy Science 304 2004 1497 1500 Epub 2004 Apr 1429
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3
  • 8
    • 1842451619 scopus 로고    scopus 로고
    • The role of 18f-fdg pet in staging and early prediction of response to therapy of recurrent gastrointestinal stromal tumors
    • I. Gayed, T. Vu, R. Iyer, and et al. The role of 18f-fdg pet in staging and early prediction of response to therapy of recurrent gastrointestinal stromal tumors J Nucl Med 45 2004 17 21
    • (2004) J Nucl Med , vol.45 , pp. 17-21
    • Gayed, I.1    Vu, T.2    Iyer, R.3
  • 9
    • 0002417975 scopus 로고
    • Overview of biological markers
    • B. Hulka, J. Griffith, T. Wilcosky, Oxford University Press New York
    • B. Hulka Overview of biological markers B. Hulka, J. Griffith, T. Wilcosky, Biological markers in epidemiology 1990 Oxford University Press New York 3 15
    • (1990) Biological Markers in Epidemiology , pp. 3-15
    • Hulka, B.1
  • 10
    • 0038004636 scopus 로고    scopus 로고
    • Clinical biomarkers in drug discovery and development
    • R. Frank, and R. Hargreaves Clinical biomarkers in drug discovery and development Nat Rev Drug Discov 2 2003 566 580
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 566-580
    • Frank, R.1    Hargreaves, R.2
  • 11
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • doi:610.1016/j.cell.2011.02.013
    • D. Hanahan, and R.A. Weinberg Hallmarks of cancer: the next generation Cell 144 2011 646 674 doi:610.1016/j.cell.2011.02.013
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 12
    • 43249123378 scopus 로고    scopus 로고
    • Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics
    • doi:1000010.1001371/journal.pgen.1000054
    • M. Garcia-Closas, P. Hall, H. Nevanlinna, and et al. Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics PLoS Genet 4 2008 e1000054 doi:1000010.1001371/journal.pgen.1000054
    • (2008) PLoS Genet , vol.4 , pp. e1000054
    • Garcia-Closas, M.1    Hall, P.2    Nevanlinna, H.3
  • 13
    • 55049112064 scopus 로고    scopus 로고
    • Stefansson K: Sequence variant on 8q24 confers susceptibility to urinary bladder cancer
    • doi:1310.1038/ng. 1229, Epub 2008 Sep. 1314
    • L.A. Kiemeney, S. Thorlacius, P. Sulem, and et al. Stefansson K: sequence variant on 8q24 confers susceptibility to urinary bladder cancer Nat Genet 40 2008 1307 1312 doi:1310.1038/ng. 1229, Epub 2008 Sep. 1314
    • (2008) Nat Genet , vol.40 , pp. 1307-1312
    • Kiemeney, L.A.1    Thorlacius, S.2    Sulem, P.3
  • 14
    • 69349102630 scopus 로고    scopus 로고
    • A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2
    • doi:1010.1038/ng. 1424, Epub 2009 Aug 1002
    • H. Song, S.J. Ramus, J. Tyrer, and et al. A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2 Nat Genet 41 2009 996 1000 doi:1010.1038/ng. 1424, Epub 2009 Aug 1002
    • (2009) Nat Genet , vol.41 , pp. 996-1000
    • Song, H.1    Ramus, S.J.2    Tyrer, J.3
  • 15
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • doi:610.1038/nature10166
    • Integrated genomic analyses of ovarian carcinoma Nature 474 2011 609 615 doi:610.1038/nature10166
    • (2011) Nature , vol.474 , pp. 609-615
  • 16
    • 0035815919 scopus 로고    scopus 로고
    • Detecting colorectal cancer in stool with the use of multiple genetic targets
    • S.M. Dong, G. Traverso, C. Johnson, and et al. Detecting colorectal cancer in stool with the use of multiple genetic targets J Natl Cancer Inst 93 2001 858 865
    • (2001) J Natl Cancer Inst , vol.93 , pp. 858-865
    • Dong, S.M.1    Traverso, G.2    Johnson, C.3
  • 17
    • 3442894720 scopus 로고    scopus 로고
    • Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer
    • M.O. Hoque, S. Begum, O. Topaloglu, and et al. Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer Cancer Res 64 2004 5511 5517
    • (2004) Cancer Res , vol.64 , pp. 5511-5517
    • Hoque, M.O.1    Begum, S.2    Topaloglu, O.3
  • 18
    • 33749024160 scopus 로고    scopus 로고
    • Detection of aberrant methylation of four genes in plasma DNA for the detection of breast cancer
    • Epub 2006 Aug 4214
    • M.O. Hoque, Q. Feng, P. Toure, and et al. Detection of aberrant methylation of four genes in plasma DNA for the detection of breast cancer J Clin Oncol 24 2006 4262 4269 Epub 2006 Aug 4214
    • (2006) J Clin Oncol , vol.24 , pp. 4262-4269
    • Hoque, M.O.1    Feng, Q.2    Toure, P.3
  • 19
    • 1842426642 scopus 로고    scopus 로고
    • Detection of promoter hypermethylation of multiple genes in the tumor and bronchoalveolar lavage of patients with lung cancer
    • O. Topaloglu, M.O. Hoque, Y. Tokumaru, and et al. Detection of promoter hypermethylation of multiple genes in the tumor and bronchoalveolar lavage of patients with lung cancer Clin Cancer Res 10 2004 2284 2288
    • (2004) Clin Cancer Res , vol.10 , pp. 2284-2288
    • Topaloglu, O.1    Hoque, M.O.2    Tokumaru, Y.3
  • 20
    • 13444271002 scopus 로고    scopus 로고
    • Molecular analysis of apc promoter methylation and protein expression in colorectal cancer metastasis
    • Sep Epub 2004
    • J. Chen, C. Rocken, C. Lofton-Day, and et al. Molecular analysis of apc promoter methylation and protein expression in colorectal cancer metastasis Carcinogenesis 2005 26 Sep 2016 37 43 Epub 2004
    • (2016) Carcinogenesis , vol.2005 , Issue.26 , pp. 37-43
    • Chen, J.1    Rocken, C.2    Lofton-Day, C.3
  • 21
    • 84879461124 scopus 로고    scopus 로고
    • Combining urinary detection of tmprss2: Erg and pca3 with serum psa to predict diagnosis of prostate cancer
    • doi:510.1016/j.urolonc.2011.1004.1001. Epub 2011 May 1019
    • S.S. Salami, F. Schmidt, B. Laxman, and et al. Combining urinary detection of tmprss2: Erg and pca3 with serum psa to predict diagnosis of prostate cancer Urol Oncol 31 2013 566 571 doi:510.1016/j.urolonc.2011.1004.1001. Epub 2011 May 1019
    • (2013) Urol Oncol , vol.31 , pp. 566-571
    • Salami, S.S.1    Schmidt, F.2    Laxman, B.3
  • 22
    • 84905981209 scopus 로고    scopus 로고
    • Molecular pathology and genetics of gastrointestinal neuroendocrine tumours
    • M.A. Lewis, and J.C. Yao Molecular pathology and genetics of gastrointestinal neuroendocrine tumours Curr Opin Endocrinol Diabetes Obes 4 2013 4
    • (2013) Curr Opin Endocrinol Diabetes Obes , vol.4 , pp. 4
    • Lewis, M.A.1    Yao, J.C.2
  • 23
  • 24
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • T. Reya, S.J. Morrison, M.F. Clarke, and et al. Stem cells, cancer, and cancer stem cells Nature 414 2001 105 111
    • (2001) Nature , vol.414 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3
  • 25
    • 78650959663 scopus 로고    scopus 로고
    • Massive genomic rearrangement acquired in a single catastrophic event during cancer development
    • P.J. Stephens, C.D. Greenman, B. Fu, and et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development Cell 144 2011 27 40 10.1016/j.cell.2010.1011.1055
    • (2011) Cell , vol.144 , pp. 27-40
    • Stephens, P.J.1    Greenman, C.D.2    Fu, B.3
  • 26
    • 79953147370 scopus 로고    scopus 로고
    • A perspective on cancer cell metastasis
    • doi:1510.1126/science.1203543
    • C.L. Chaffer, and R.A. Weinberg A perspective on cancer cell metastasis Science 331 2011 1559 1564 doi:1510.1126/science.1203543
    • (2011) Science , vol.331 , pp. 1559-1564
    • Chaffer, C.L.1    Weinberg, R.A.2
  • 27
    • 0033933685 scopus 로고    scopus 로고
    • An interpretation for the roc curve and inference using glm procedures
    • M.S. Pepe An interpretation for the roc curve and inference using glm procedures Biometrics 56 2000 352 359
    • (2000) Biometrics , vol.56 , pp. 352-359
    • Pepe, M.S.1
  • 28
    • 0032883399 scopus 로고    scopus 로고
    • The interpretation of diagnostic tests
    • D.E. Shapiro The interpretation of diagnostic tests Stat Methods Med Res 8 1999 113 134
    • (1999) Stat Methods Med Res , vol.8 , pp. 113-134
    • Shapiro, D.E.1
  • 29
    • 38149096396 scopus 로고    scopus 로고
    • Understanding and using sensitivity, specificity and predictive values
    • R. Parikh, A. Mathai, S. Parikh, and et al. Understanding and using sensitivity, specificity and predictive values Indian J Ophthalmol 56 2008 45 50
    • (2008) Indian J Ophthalmol , vol.56 , pp. 45-50
    • Parikh, R.1    Mathai, A.2    Parikh, S.3
  • 30
    • 84871832304 scopus 로고    scopus 로고
    • Trends of incidence and survival of gastrointestinal neuroendocrine tumors in the United States: A seer analysis
    • V.L. Tsikitis, B.C. Wertheim, and M.A. Guerrero Trends of incidence and survival of gastrointestinal neuroendocrine tumors in the united states: a seer analysis J Cancer 3 2012 292 302
    • (2012) J Cancer , vol.3 , pp. 292-302
    • Tsikitis, V.L.1    Wertheim, B.C.2    Guerrero, M.A.3
  • 31
    • 84880064107 scopus 로고    scopus 로고
    • Biomarkers in neuroendocrine tumors
    • M. Duque, I.M. Modlin, A. Gupta, and et al. Biomarkers in neuroendocrine tumors JOP J Pancreas 14 2013 372 376
    • (2013) JOP J Pancreas , vol.14 , pp. 372-376
    • Duque, M.1    Modlin, I.M.2    Gupta, A.3
  • 32
    • 84940532180 scopus 로고    scopus 로고
    • Biomarkers for neuroendocrine tumor disease: A delphic consensus assessment of multianalytes, genomics, circulating cells and monoanalytes
    • K. Oberg, I. Modlin, W. DeHerder, and et al. Biomarkers for neuroendocrine tumor disease: a delphic consensus assessment of multianalytes, genomics, circulating cells and monoanalytes Lancet Oncol 16 2015 e435 e446
    • (2015) Lancet Oncol , vol.16 , pp. e435-e446
    • Oberg, K.1    Modlin, I.2    DeHerder, W.3
  • 33
    • 0038476015 scopus 로고    scopus 로고
    • A comparison between three commercial kits for chromogranin a measurements
    • M. Stridsberg, B. Eriksson, K. Oberg, and et al. A comparison between three commercial kits for chromogranin a measurements J Endocrinol 177 2003 337 341
    • (2003) J Endocrinol , vol.177 , pp. 337-341
    • Stridsberg, M.1    Eriksson, B.2    Oberg, K.3
  • 34
    • 84871752522 scopus 로고    scopus 로고
    • Standardization of diagnostic biomarker concentrations in urine: The hematuria caveat
    • C.N. Reid, M. Stevenson, F. Abogunrin, and et al. Standardization of diagnostic biomarker concentrations in urine: the hematuria caveat PLoS One 7 2012
    • (2012) PLoS One , vol.7
    • Reid, C.N.1    Stevenson, M.2    Abogunrin, F.3
  • 36
    • 84921433441 scopus 로고    scopus 로고
    • Prediagnostic transcriptomic markers of chronic lymphocytic leukemia reveal perturbations 10 years before diagnosis
    • doi:1010.1093/annonc/mdu1056. Epub 2014 Feb 1020
    • M. Chadeau-Hyam, R.C. Vermeulen, D.G. Hebels, and et al. Prediagnostic transcriptomic markers of chronic lymphocytic leukemia reveal perturbations 10 years before diagnosis Ann Oncol 25 2014 1065 1072 doi:1010.1093/annonc/mdu1056. Epub 2014 Feb 1020
    • (2014) Ann Oncol , vol.25 , pp. 1065-1072
    • Chadeau-Hyam, M.1    Vermeulen, R.C.2    Hebels, D.G.3
  • 38
    • 84857852641 scopus 로고    scopus 로고
    • Limitations of chromogranin a in clinical practice
    • doi:110.3109/1354750X.1352012.1654511. Epub 1352012 Feb 1354756
    • V. Marotta, V. Nuzzo, T. Ferrara, and et al. Limitations of chromogranin a in clinical practice Biomarkers 17 2012 186 191 doi:110.3109/1354750X.1352012.1654511. Epub 1352012 Feb 1354756
    • (2012) Biomarkers , vol.17 , pp. 186-191
    • Marotta, V.1    Nuzzo, V.2    Ferrara, T.3
  • 39
    • 77956342399 scopus 로고    scopus 로고
    • Chromogranin a - Biological function and clinical utility in neuro endocrine tumor disease
    • I.M. Modlin, B.I. Gustafsson, S.F. Moss, and et al. Chromogranin a - biological function and clinical utility in neuro endocrine tumor disease Ann Surg Oncol 17 2010 2427 2443
    • (2010) Ann Surg Oncol , vol.17 , pp. 2427-2443
    • Modlin, I.M.1    Gustafsson, B.I.2    Moss, S.F.3
  • 40
    • 84871379143 scopus 로고    scopus 로고
    • Chromogranin a is a sensitive marker of progression or regression in ileo-cecal neuroendocrine tumors
    • Epub 00362012 Oct 00365524
    • K.H. Jensen, L. Hilsted, C. Jensen, and et al. Chromogranin a is a sensitive marker of progression or regression in ileo-cecal neuroendocrine tumors Scand J Gastroenterol 48 2013 70 77 10.3109/00365521.00362012.00733953 Epub 00362012 Oct 00365524
    • (2013) Scand J Gastroenterol , vol.48 , pp. 70-77
    • Jensen, K.H.1    Hilsted, L.2    Jensen, C.3
  • 41
    • 34547821431 scopus 로고    scopus 로고
    • Italian CromaNet Working G: Chromogranin a as a marker of neuroendocrine neoplasia: An Italian multicenter study
    • M.C. Zatelli, M. Torta, A. Leon, and et al. Italian CromaNet Working G: chromogranin a as a marker of neuroendocrine neoplasia: an Italian multicenter study Endocr Relat Cancer 14 2007 473 482
    • (2007) Endocr Relat Cancer , vol.14 , pp. 473-482
    • Zatelli, M.C.1    Torta, M.2    Leon, A.3
  • 42
    • 37449029464 scopus 로고    scopus 로고
    • The current status of gastroenteropancreatic neuroendocrine tumors
    • I.M. Modlin, K. Oberg, D.C. Chung, and et al. The current status of gastroenteropancreatic neuroendocrine tumors Lancet Oncol 9 2008 61 72
    • (2008) Lancet Oncol , vol.9 , pp. 61-72
    • Modlin, I.M.1    Oberg, K.2    Chung, D.C.3
  • 43
    • 33747496353 scopus 로고    scopus 로고
    • Gastrointestinal carcinoids: The evolution of diagnostic strategies
    • I.M. Modlin, I. Latich, M. Zikusoka, and et al. Gastrointestinal carcinoids: the evolution of diagnostic strategies J Clin Gastroenterol 40 2006 572 582
    • (2006) J Clin Gastroenterol , vol.40 , pp. 572-582
    • Modlin, I.M.1    Latich, I.2    Zikusoka, M.3
  • 44
    • 84876103467 scopus 로고    scopus 로고
    • Biochemical markers for gastroenteropancreatic neuroendocrine tumours (gep-nets)
    • doi:710.1016/j.bpg.2012.1012.1006
    • G. Kanakis, and G. Kaltsas Biochemical markers for gastroenteropancreatic neuroendocrine tumours (gep-nets) Best Pract Res Clin Gastroenterol 26 2012 791 802 doi:710.1016/j.bpg.2012.1012.1006
    • (2012) Best Pract Res Clin Gastroenterol , vol.26 , pp. 791-802
    • Kanakis, G.1    Kaltsas, G.2
  • 45
    • 0034007505 scopus 로고    scopus 로고
    • Elevated serum chromogranin a is detectable in patients with carcinomas at advanced disease stages
    • J.T. Wu, A.J. Erickson, K.C. Tsao, and et al. Elevated serum chromogranin a is detectable in patients with carcinomas at advanced disease stages Ann Clin Lab Sci 30 2000 175 178
    • (2000) Ann Clin Lab Sci , vol.30 , pp. 175-178
    • Wu, J.T.1    Erickson, A.J.2    Tsao, K.C.3
  • 46
    • 27744446809 scopus 로고    scopus 로고
    • Chromogranin a expression in familial versus sporadic prostate cancer
    • A. Sciarra, S. Monti, V. Gentile, and et al. Chromogranin a expression in familial versus sporadic prostate cancer Urology 66 2005 1010 1014
    • (2005) Urology , vol.66 , pp. 1010-1014
    • Sciarra, A.1    Monti, S.2    Gentile, V.3
  • 47
    • 0025360974 scopus 로고
    • Chromogranin a in uremia: Progressive retention of immunoreactive fragments
    • R.J. Hsiao, M.S. Mezger, and D.T. O'Connor Chromogranin a in uremia: progressive retention of immunoreactive fragments Kidney Int 37 1990 955 964
    • (1990) Kidney Int , vol.37 , pp. 955-964
    • Hsiao, R.J.1    Mezger, M.S.2    O'Connor, D.T.3
  • 48
    • 78049498837 scopus 로고    scopus 로고
    • A meal test improves the specificity of chromogranin a as a marker of neuroendocrine neoplasia
    • Epub 2010 May 2018
    • C.S. Jianu, R. Fossmark, U. Syversen, and et al. A meal test improves the specificity of chromogranin a as a marker of neuroendocrine neoplasia Tumour Biol 31 2010 373 380 Epub 2010 May 2018
    • (2010) Tumour Biol , vol.31 , pp. 373-380
    • Jianu, C.S.1    Fossmark, R.2    Syversen, U.3
  • 49
    • 79951735265 scopus 로고    scopus 로고
    • The clinical relevance of chromogranin a as a biomarker for gastroenteropancreatic neuroendocrine tumors
    • viii. doi:110.1016/j.ecl.2010.1012.1001
    • B. Lawrence, B.I. Gustafsson, M. Kidd, and et al. The clinical relevance of chromogranin a as a biomarker for gastroenteropancreatic neuroendocrine tumors Endocrinol Metab Clin North Am 40 2011 111 134 viii. doi:110.1016/j.ecl.2010.1012.1001
    • (2011) Endocrinol Metab Clin North Am , vol.40 , pp. 111-134
    • Lawrence, B.1    Gustafsson, B.I.2    Kidd, M.3
  • 50
    • 84878016673 scopus 로고    scopus 로고
    • Prevalence and associations of the use of proton-pump inhibitors in nursing homes: A cross-sectional study
    • doi:210.1016/j.jamda.2012.1010.1018. Epub 2012 Dec 1011
    • P. de Souto Barreto, M. Lapeyre-Mestre, C. Mathieu, and et al. Prevalence and associations of the use of proton-pump inhibitors in nursing homes: a cross-sectional study J Am Med Dir Assoc 14 2013 265 269 doi:210.1016/j.jamda.2012.1010.1018. Epub 2012 Dec 1011
    • (2013) J Am Med Dir Assoc , vol.14 , pp. 265-269
    • De Souto Barreto, P.1    Lapeyre-Mestre, M.2    Mathieu, C.3
  • 51
    • 79961209469 scopus 로고    scopus 로고
    • Insights into gastroesophageal reflux disease-associated dyspeptic symptoms
    • doi:810.1016/j.cgh.2011.1005.1015. Epub 2011 May 1020
    • L.B. Gerson, P.J. Kahrilas, and R. Fass Insights into gastroesophageal reflux disease-associated dyspeptic symptoms Clin Gastroenterol Hepatol 9 2011 824 833 doi:810.1016/j.cgh.2011.1005.1015. Epub 2011 May 1020
    • (2011) Clin Gastroenterol Hepatol , vol.9 , pp. 824-833
    • Gerson, L.B.1    Kahrilas, P.J.2    Fass, R.3
  • 52
    • 34249941287 scopus 로고    scopus 로고
    • Chromogranin a: Is it a useful marker of neuroendocrine tumors?
    • D. Campana, F. Nori, L. Piscitelli, and et al. Chromogranin a: is it a useful marker of neuroendocrine tumors? JCO 25 2007 1967 1973
    • (2007) JCO , vol.25 , pp. 1967-1973
    • Campana, D.1    Nori, F.2    Piscitelli, L.3
  • 53
    • 0028874025 scopus 로고
    • Measurements of chromogranin a, chromogranin b (secretogranin i), chromogranin c (secretogranin II) and pancreastatin in plasma and urine from patients with carcinoid tumours and endocrine pancreatic tumours
    • M. Stridsberg, K. Oberg, Q. Li, and et al. Measurements of chromogranin a, chromogranin b (secretogranin i), chromogranin c (secretogranin ii) and pancreastatin in plasma and urine from patients with carcinoid tumours and endocrine pancreatic tumours J Endocrinol 144 1995 49 59
    • (1995) J Endocrinol , vol.144 , pp. 49-59
    • Stridsberg, M.1    Oberg, K.2    Li, Q.3
  • 54
    • 0038798531 scopus 로고    scopus 로고
    • Serum peptide profiles in patients with carcinoid tumors
    • K. Calhoun, S. Toth-Fejel, J. Cheek, and et al. Serum peptide profiles in patients with carcinoid tumors Am J Surg 186 2003 28 31
    • (2003) Am J Surg , vol.186 , pp. 28-31
    • Calhoun, K.1    Toth-Fejel, S.2    Cheek, J.3
  • 55
    • 84859965815 scopus 로고    scopus 로고
    • A prospective evaluation of the effect of chronic proton pump inhibitor use on plasma biomarker levels in humans
    • doi:510.1097/MPA.1090b1013e318243a318240b318246
    • D. Raines, M. Chester, A.E. Diebold, and et al. A prospective evaluation of the effect of chronic proton pump inhibitor use on plasma biomarker levels in humans Pancreas 41 2012 508 511 doi:510.1097/MPA.1090b1013e318243a318240b318246
    • (2012) Pancreas , vol.41 , pp. 508-511
    • Raines, D.1    Chester, M.2    Diebold, A.E.3
  • 56
    • 84859929476 scopus 로고    scopus 로고
    • Serum pancreastatin: The long sought for universal, sensitive, specific tumor marker for neuroendocrine tumors (nets)?
    • T. Ito, H. Igarashi, and R.T. Jensen Serum pancreastatin: the long sought for universal, sensitive, specific tumor marker for neuroendocrine tumors (nets)? Pancreas 41 2012 505 507
    • (2012) Pancreas , vol.41 , pp. 505-507
    • Ito, T.1    Igarashi, H.2    Jensen, R.T.3
  • 57
    • 33750296895 scopus 로고    scopus 로고
    • Circulating markers of prognosis and response to treatment in patients with midgut carcinoid tumours
    • G.B. Turner, B.T. Johnston, D.R. McCance, and et al. Circulating markers of prognosis and response to treatment in patients with midgut carcinoid tumours Gut 55 2006 1586 1591
    • (2006) Gut , vol.55 , pp. 1586-1591
    • Turner, G.B.1    Johnston, B.T.2    McCance, D.R.3
  • 58
    • 0031870837 scopus 로고    scopus 로고
    • Effect of human pancreastatin peptide (hp-16) on oral glucose tolerance in man
    • E.G. Siegel, B. Gallwitz, U.R. Folsch, and et al. Effect of human pancreastatin peptide (hp-16) on oral glucose tolerance in man Exp Clin Endocrinol Diabetes 106 1998 178 182
    • (1998) Exp Clin Endocrinol Diabetes , vol.106 , pp. 178-182
    • Siegel, E.G.1    Gallwitz, B.2    Folsch, U.R.3
  • 59
    • 84887601829 scopus 로고    scopus 로고
    • Pancreastatin is an endogenous peptide that regulates glucose homeostasis
    • doi:1010.1152/physiolgenomics.00131.02013. Epub 02013 Sep. 00124
    • G.R. Valicherla, Z. Hossain, S.K. Mahata, and et al. Pancreastatin is an endogenous peptide that regulates glucose homeostasis Physiol Genomics 45 2013 1060 1071 doi:1010.1152/physiolgenomics.00131.02013. Epub 02013 Sep. 00124
    • (2013) Physiol Genomics , vol.45 , pp. 1060-1071
    • Valicherla, G.R.1    Hossain, Z.2    Mahata, S.K.3
  • 60
    • 0034524701 scopus 로고    scopus 로고
    • Pancreastatin plasma levels in patients with primary hyperparathyroidism
    • A. Bergenfelz, L. Luts, T.B. Jensen, and et al. Pancreastatin plasma levels in patients with primary hyperparathyroidism World J Surg 24 2000 1579 1583
    • (2000) World J Surg , vol.24 , pp. 1579-1583
    • Bergenfelz, A.1    Luts, L.2    Jensen, T.B.3
  • 61
    • 77954099329 scopus 로고    scopus 로고
    • Development of a highly sensitive and specific carboxy-terminal human pancreastatin assay to monitor neuroendocrine tumor behavior
    • doi:610.1097/MPA.1090b1013e3181c1068d1097a
    • T.M. O'Dorisio, S.R. Krutzik, E.A. Woltering, and et al. Development of a highly sensitive and specific carboxy-terminal human pancreastatin assay to monitor neuroendocrine tumor behavior Pancreas 39 2010 611 616 doi:610.1097/MPA.1090b1013e3181c1068d1097a
    • (2010) Pancreas , vol.39 , pp. 611-616
    • O'Dorisio, T.M.1    Krutzik, S.R.2    Woltering, E.A.3
  • 62
    • 78649909456 scopus 로고    scopus 로고
    • Granin-derived peptides as diagnostic and prognostic markers for endocrine tumors
    • Epub 2009 Nov 1026
    • J.M. Conlon Granin-derived peptides as diagnostic and prognostic markers for endocrine tumors Regul Pept 165 2010 5 11 10.1016/j.regpep.2009.1011.1013 Epub 2009 Nov 1026
    • (2010) Regul Pept , vol.165 , pp. 5-11
    • Conlon, J.M.1
  • 63
    • 84899559367 scopus 로고    scopus 로고
    • The biochemical utility of chromogranin a, chromogranin b and cocaine- and amphetamine-regulated transcript for neuroendocrine neoplasia
    • Epub 0004563213482013 Aug 0004563213489612
    • P.R. Bech, N.M. Martin, R. Ramachandran, and et al. The biochemical utility of chromogranin a, chromogranin b and cocaine- and amphetamine-regulated transcript for neuroendocrine neoplasia Ann Clin Biochem 51 2014 8 21 10.1177/0004563213489670 Epub 0004563213482013 Aug 0004563213489612
    • (2014) Ann Clin Biochem , vol.51 , pp. 8-21
    • Bech, P.R.1    Martin, N.M.2    Ramachandran, R.3
  • 64
    • 84891545878 scopus 로고    scopus 로고
    • Circulating plasma and platelet 5-hydroxytryptamine in carcinoid heart disease: A pilot study
    • S. Bhattacharyya, A. Jagroop, D.M. Gujral, and et al. Circulating plasma and platelet 5-hydroxytryptamine in carcinoid heart disease: a pilot study J Heart Valve Dis 22 2013 400 407
    • (2013) J Heart Valve Dis , vol.22 , pp. 400-407
    • Bhattacharyya, S.1    Jagroop, A.2    Gujral, D.M.3
  • 65
    • 0033197983 scopus 로고    scopus 로고
    • Chromogranin a, neuron specific enolase, carcinoembryonic antigen, and hydroxyindole acetic acid evaluation in patients with neuroendocrine tumors
    • E. Bajetta, L. Ferrari, A. Martinetti, and et al. Chromogranin a, neuron specific enolase, carcinoembryonic antigen, and hydroxyindole acetic acid evaluation in patients with neuroendocrine tumors Cancer 86 1999 858 865
    • (1999) Cancer , vol.86 , pp. 858-865
    • Bajetta, E.1    Ferrari, L.2    Martinetti, A.3
  • 66
    • 84884213585 scopus 로고    scopus 로고
    • A single fasting plasma 5-hiaa value correlates with 24-hour urinary 5-hiaa values and other biomarkers in midgut neuroendocrine tumors (nets)
    • M.R. Tellez, G. Mamikunian, T.M. O'Dorisio, and et al. A single fasting plasma 5-hiaa value correlates with 24-hour urinary 5-hiaa values and other biomarkers in midgut neuroendocrine tumors (nets) Pancreas 42 2013 405 410
    • (2013) Pancreas , vol.42 , pp. 405-410
    • Tellez, M.R.1    Mamikunian, G.2    O'Dorisio, T.M.3
  • 67
    • 84884196957 scopus 로고    scopus 로고
    • The association of a panel of biomarkers with the presence and severity of carcinoid heart disease: A cross-sectional study
    • R. Dobson, M.I. Burgess, M. Banks, and et al. The association of a panel of biomarkers with the presence and severity of carcinoid heart disease: a cross-sectional study PLoS One 8 2013
    • (2013) PLoS One , vol.8
    • Dobson, R.1    Burgess, M.I.2    Banks, M.3
  • 68
    • 7344256182 scopus 로고    scopus 로고
    • Neuron-specific enolase and chromogranin a as markers of neuroendocrine tumours
    • E. Baudin, A. Gigliotti, M. Ducreux, and et al. Neuron-specific enolase and chromogranin a as markers of neuroendocrine tumours Br J Cancer 78 1998 1102 1107
    • (1998) Br J Cancer , vol.78 , pp. 1102-1107
    • Baudin, E.1    Gigliotti, A.2    Ducreux, M.3
  • 69
    • 0033843657 scopus 로고    scopus 로고
    • Tumor markers in neuroendocrine tumors
    • B. Eriksson, K. Oberg, and M. Stridsberg Tumor markers in neuroendocrine tumors Digestion 62 Suppl. 1 2000 33 38
    • (2000) Digestion , vol.62 , pp. 33-38
    • Eriksson, B.1    Oberg, K.2    Stridsberg, M.3
  • 70
    • 0025609381 scopus 로고
    • The utility of circulating levels of human pancreatic polypeptide as a marker for islet cell tumors
    • discussion 1115-1116
    • H.N. Langstein, J.A. Norton, V. Chiang, and et al. The utility of circulating levels of human pancreatic polypeptide as a marker for islet cell tumors Surgery 108 1990 1109 1115 discussion 1115-1116
    • (1990) Surgery , vol.108 , pp. 1109-1115
    • Langstein, H.N.1    Norton, J.A.2    Chiang, V.3
  • 71
    • 84864127592 scopus 로고    scopus 로고
    • Is the combination of chromogranin a and pancreatic polypeptide serum determinations of interest in the diagnosis and follow-up of gastro-entero-pancreatic neuroendocrine tumours?
    • T. Walter, L. Chardon, X. Chopin-laly, and et al. Is the combination of chromogranin a and pancreatic polypeptide serum determinations of interest in the diagnosis and follow-up of gastro-entero-pancreatic neuroendocrine tumours? Eur J Cancer 48 2012 1766 1773
    • (2012) Eur J Cancer , vol.48 , pp. 1766-1773
    • Walter, T.1    Chardon, L.2    Chopin-Laly, X.3
  • 72
    • 0023055391 scopus 로고
    • Role of neuropeptides and serotonin in the diagnosis of carcinoid tumors
    • J.M. Feldman, and T.M. O'Dorisio Role of neuropeptides and serotonin in the diagnosis of carcinoid tumors Am J Med 81 1986 41 48
    • (1986) Am J Med , vol.81 , pp. 41-48
    • Feldman, J.M.1    O'Dorisio, T.M.2
  • 73
    • 82355172693 scopus 로고    scopus 로고
    • An elevated progastrin-releasing peptide level in patients with well-differentiated neuroendocrine tumours indicates a primary tumour in the lung and predicts a shorter survival
    • doi:2610.1093/annonc/mdr2007. Epub 2011 Mar 2617
    • C.M. Korse, B.G. Taal, J.M. Bonfrer, and et al. An elevated progastrin-releasing peptide level in patients with well-differentiated neuroendocrine tumours indicates a primary tumour in the lung and predicts a shorter survival Ann Oncol 22 2011 2625 2630 doi:2610.1093/annonc/mdr2007. Epub 2011 Mar 2617
    • (2011) Ann Oncol , vol.22 , pp. 2625-2630
    • Korse, C.M.1    Taal, B.G.2    Bonfrer, J.M.3
  • 74
    • 70349328339 scopus 로고    scopus 로고
    • Chromogranin-a and n-terminal pro-brain natriuretic peptide: An excellent pair of biomarkers for diagnostics in patients with neuroendocrine tumor
    • C.M. Korse, B.G. Taal, CAd Groot, and et al. Chromogranin-a and n-terminal pro-brain natriuretic peptide: an excellent pair of biomarkers for diagnostics in patients with neuroendocrine tumor JCO 27 2009 4293 4299
    • (2009) JCO , vol.27 , pp. 4293-4299
    • Korse, C.M.1    Taal, B.G.2    Groot, C.3
  • 75
    • 84893854805 scopus 로고    scopus 로고
    • Connective tissue growth factor (ctgf/ccn2): Diagnostic and prognostic value in acute heart failure
    • doi:110.1007/s00392-00013-00626-00396. Epub 02013 Oct 00322
    • M. Behnes, M. Brueckmann, S. Lang, and et al. Connective tissue growth factor (ctgf/ccn2): diagnostic and prognostic value in acute heart failure Clin Res Cardiol 103 2014 107 116 doi:110.1007/s00392-00013-00626-00396. Epub 02013 Oct 00322
    • (2014) Clin Res Cardiol , vol.103 , pp. 107-116
    • Behnes, M.1    Brueckmann, M.2    Lang, S.3
  • 76
    • 76749160318 scopus 로고    scopus 로고
    • Plasma ccn2/connective tissue growth factor is associated with right ventricular dysfunction in patients with neuroendocrine tumors
    • D.S. Bergestuen, J. Gravning, K.H. Haugaa, and et al. Plasma ccn2/connective tissue growth factor is associated with right ventricular dysfunction in patients with neuroendocrine tumors BMC Cancer 10 2010 6
    • (2010) BMC Cancer , vol.10 , pp. 6
    • Bergestuen, D.S.1    Gravning, J.2    Haugaa, K.H.3
  • 77
    • 84873374248 scopus 로고    scopus 로고
    • Circulating tumor cells as prognostic markers in neuroendocrine tumors
    • doi:310.1200/JCO.2012.1244.2905. Epub 2012 Dec 1217
    • M.S. Khan, A. Kirkwood, T. Tsigani, and et al. Circulating tumor cells as prognostic markers in neuroendocrine tumors J Clin Oncol 31 2013 365 372 doi:310.1200/JCO.2012.1244.2905. Epub 2012 Dec 1217
    • (2013) J Clin Oncol , vol.31 , pp. 365-372
    • Khan, M.S.1    Kirkwood, A.2    Tsigani, T.3
  • 78
    • 79251490733 scopus 로고    scopus 로고
    • Circulating tumor cells and epcam expression in neuroendocrine tumors
    • Epub 2011 Jan 2011
    • M.S. Khan, T. Tsigani, M. Rashid, and et al. Circulating tumor cells and epcam expression in neuroendocrine tumors Clin Cancer Res 17 2011 337 345 Epub 2011 Jan 2011
    • (2011) Clin Cancer Res , vol.17 , pp. 337-345
    • Khan, M.S.1    Tsigani, T.2    Rashid, M.3
  • 79
    • 84887989138 scopus 로고    scopus 로고
    • Metabonomic profiling: A novel approach in neuroendocrine neoplasias
    • discussion 1192-1183
    • J.M. Kinross, P. Drymousis, B. Jimenez, and et al. Metabonomic profiling: a novel approach in neuroendocrine neoplasias Surgery 154 2013 1185 1192 discussion 1192-1183
    • (2013) Surgery , vol.154 , pp. 1185-1192
    • Kinross, J.M.1    Drymousis, P.2    Jimenez, B.3
  • 80
    • 78651245684 scopus 로고    scopus 로고
    • Paraneoplastic antigen ma2 autoantibodies as specific blood biomarkers for detection of early recurrence of small intestine neuroendocrine tumors
    • T. Cui, M. Hurtig, G. Elgue, and et al. Paraneoplastic antigen ma2 autoantibodies as specific blood biomarkers for detection of early recurrence of small intestine neuroendocrine tumors PLoS One 5 2010 e16010
    • (2010) PLoS One , vol.5 , pp. e16010
    • Cui, T.1    Hurtig, M.2    Elgue, G.3
  • 81
    • 52449104598 scopus 로고    scopus 로고
    • Priorities for improving the management of gastroenteropancreatic neuroendocrine tumors
    • Epub 2008 Sep. 1289
    • I.M. Modlin, S.F. Moss, D.C. Chung, and et al. Priorities for improving the management of gastroenteropancreatic neuroendocrine tumors J Natl Cancer Inst 100 2008 1282 1289 Epub 2008 Sep. 1289
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1282-1289
    • Modlin, I.M.1    Moss, S.F.2    Chung, D.C.3
  • 82
    • 84906827234 scopus 로고    scopus 로고
    • Blood transcript analysis and metastatic recurrent small bowel carcinoid management
    • I.M. Modlin, I. Drozdov, L. Bodei, and et al. Blood transcript analysis and metastatic recurrent small bowel carcinoid management BMC Cancer 14 2014 564 10.1186/1471-2407-1114-1564
    • (2014) BMC Cancer , vol.14 , pp. 564
    • Modlin, I.M.1    Drozdov, I.2    Bodei, L.3
  • 83
    • 84904083586 scopus 로고    scopus 로고
    • Gene network-based analysis identifies two potential subtypes of small intestinal neuroendocrine tumors
    • M. Kidd, I.M. Modlin, and I. Drozdov Gene network-based analysis identifies two potential subtypes of small intestinal neuroendocrine tumors BMC Genomics 15 2014 595 10.1186/1471-2164-1115-1595
    • (2014) BMC Genomics , vol.15 , pp. 595
    • Kidd, M.1    Modlin, I.M.2    Drozdov, I.3
  • 84
    • 84928954842 scopus 로고    scopus 로고
    • A PCR blood test outperforms chromogranin a in carcinoid detection and is unaffected by ppis
    • I.M. Modlin, H. Aslanian, L. Bodei, and et al. A pcr blood test outperforms chromogranin a in carcinoid detection and is unaffected by ppis Endocr Connect 14 2014 14 0100
    • (2014) Endocr Connect , vol.14 , pp. 14-0100
    • Modlin, I.M.1    Aslanian, H.2    Bodei, L.3
  • 85
    • 84939257826 scopus 로고    scopus 로고
    • The clinical utility of a novel blood-based multi-transcriptome assay for the diagnosis of neuroendocrine tumors of the gastrointestinal tract
    • doi:1210.1038/ajg.2015.1160. Epub 2015 Jun 1222
    • I.M. Modlin, M. Kidd, L. Bodei, and et al. The clinical utility of a novel blood-based multi-transcriptome assay for the diagnosis of neuroendocrine tumors of the gastrointestinal tract Am J Gastroenterol 110 2015 1223 1232 doi:1210.1038/ajg.2015.1160. Epub 2015 Jun 1222
    • (2015) Am J Gastroenterol , vol.110 , pp. 1223-1232
    • Modlin, I.M.1    Kidd, M.2    Bodei, L.3
  • 86
    • 84940109492 scopus 로고    scopus 로고
    • Blood and tissue net gene cluster analysis correlate, define hallmarks and predict disease status
    • M. Kidd, I. Drozdov, and I. Modlin Blood and tissue net gene cluster analysis correlate, define hallmarks and predict disease status Endocr Relat Cancer 22 2015 561 575
    • (2015) Endocr Relat Cancer , vol.22 , pp. 561-575
    • Kidd, M.1    Drozdov, I.2    Modlin, I.3
  • 87
    • 84880071683 scopus 로고    scopus 로고
    • A multitranscript blood neuroendocrine tumor molecular signature to identify treatment efficacy and disease progress
    • I. Modlin, I. Drozdov, and M. Kidd A multitranscript blood neuroendocrine tumor molecular signature to identify treatment efficacy and disease progress J Clin Oncol 31 Suppl. 2013 A4137
    • (2013) J Clin Oncol , vol.31 , pp. A4137
    • Modlin, I.1    Drozdov, I.2    Kidd, M.3
  • 88
    • 84951760969 scopus 로고    scopus 로고
    • Blood measurement of neuroendocrine gene transcripts defines the effectiveness of surgical resection and ablation strategies
    • I. Modlin, A. Frilling, R. Salem, and et al. Blood measurement of neuroendocrine gene transcripts defines the effectiveness of surgical resection and ablation strategies Surgery 159 1 2016 336 347
    • (2016) Surgery , vol.159 , Issue.1 , pp. 336-347
    • Modlin, I.1    Frilling, A.2    Salem, R.3
  • 89
    • 84937811811 scopus 로고    scopus 로고
    • Gene transcript analysis blood values correlate with (68)ga-dota-somatostatin analog (ssa) pet/ct imaging in neuroendocrine tumors and can define disease status
    • doi:1310.1007/s00259-00015-03075-00259. Epub 02015 May 00257
    • L. Bodei, M. Kidd, I.M. Modlin, and et al. Gene transcript analysis blood values correlate with (68)ga-dota-somatostatin analog (ssa) pet/ct imaging in neuroendocrine tumors and can define disease status Eur J Nucl Med Mol Imaging 42 2015 1341 1352 doi:1310.1007/s00259-00015-03075-00259. Epub 02015 May 00257
    • (2015) Eur J Nucl Med Mol Imaging , vol.42 , pp. 1341-1352
    • Bodei, L.1    Kidd, M.2    Modlin, I.M.3
  • 90
    • 84922930634 scopus 로고    scopus 로고
    • Neuroendocrine tumor biomarkers: Current status and perspectives
    • I. Modlin, M. Kidd, A. Taylor, and et al. Neuroendocrine tumor biomarkers: current status and perspectives Neuroendocrinology 100 2014 265 277
    • (2014) Neuroendocrinology , vol.100 , pp. 265-277
    • Modlin, I.1    Kidd, M.2    Taylor, A.3
  • 91
    • 20144385756 scopus 로고    scopus 로고
    • Circulating tumor cells: A novel prognostic factor for newly diagnosed metastatic breast cancer
    • M. Cristofanilli, D.F. Hayes, G.T. Budd, and et al. Circulating tumor cells: a novel prognostic factor for newly diagnosed metastatic breast cancer J Clin Oncol 23 2005 1420 1430
    • (2005) J Clin Oncol , vol.23 , pp. 1420-1430
    • Cristofanilli, M.1    Hayes, D.F.2    Budd, G.T.3
  • 92
    • 49249130844 scopus 로고    scopus 로고
    • Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer
    • S.J. Cohen, C.J. Punt, N. Iannotti, and et al. Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer J Clin Oncol 26 2008 3213 3221
    • (2008) J Clin Oncol , vol.26 , pp. 3213-3221
    • Cohen, S.J.1    Punt, C.J.2    Iannotti, N.3
  • 93
    • 84870674044 scopus 로고    scopus 로고
    • Prognostic significance of circulating tumor cell count in patients with metastatic hormone-sensitive prostate cancer
    • 01049-01047
    • L. Resel Folkersma, L. San Jose Manso, I. Galante Romo, and et al. Prognostic significance of circulating tumor cell count in patients with metastatic hormone-sensitive prostate cancer Urology 10 2012 01049-01047
    • (2012) Urology , vol.10
    • Resel Folkersma, L.1    San Jose Manso, L.2    Galante Romo, I.3
  • 94
    • 84877921098 scopus 로고    scopus 로고
    • Mirna profiling of cancer
    • Epub 2013 Mar 1014
    • G. Di Leva, and C.M. Croce Mirna profiling of cancer Curr Opin Genet Dev 23 2013 3 11 10.1016/j.gde.2013.1001.1004 Epub 2013 Mar 1014
    • (2013) Curr Opin Genet Dev , vol.23 , pp. 3-11
    • Di Leva, G.1    Croce, C.M.2
  • 95
    • 33750600178 scopus 로고    scopus 로고
    • Microrna expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior
    • Epub 2006 Sep. 4611
    • C. Roldo, E. Missiaglia, J.P. Hagan, and et al. Microrna expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior J Clin Oncol 24 2006 4677 4684 Epub 2006 Sep. 4611
    • (2006) J Clin Oncol , vol.24 , pp. 4677-4684
    • Roldo, C.1    Missiaglia, E.2    Hagan, J.P.3
  • 96
    • 84902967350 scopus 로고    scopus 로고
    • Global microrna profiling of pancreatic neuroendocrine neoplasias
    • C. Thorns, C. Schurmann, N. Gebauer, and et al. Global microrna profiling of pancreatic neuroendocrine neoplasias Anticancer Res 34 2014 2249 2254
    • (2014) Anticancer Res , vol.34 , pp. 2249-2254
    • Thorns, C.1    Schurmann, C.2    Gebauer, N.3
  • 97
    • 84879860566 scopus 로고    scopus 로고
    • Microrna array analysis finds elevated serum mir-1290 accurately distinguishes patients with low-stage pancreatic cancer from healthy and disease controls
    • doi:3610.1158/1078-0432.CCR-3612-3092. Epub 2013 May 3622
    • A. Li, J. Yu, H. Kim, and et al. Microrna array analysis finds elevated serum mir-1290 accurately distinguishes patients with low-stage pancreatic cancer from healthy and disease controls Clin Cancer Res 19 2013 3600 3610 doi:3610.1158/1078-0432.CCR-3612-3092. Epub 2013 May 3622
    • (2013) Clin Cancer Res , vol.19 , pp. 3600-3610
    • Li, A.1    Yu, J.2    Kim, H.3
  • 98
    • 84877051451 scopus 로고    scopus 로고
    • Global microrna profiling of well-differentiated small intestinal neuroendocrine tumors
    • doi:610.1038/modpathol.2012.1216. Epub 2013 Jan 1018
    • S.C. Li, A. Essaghir, C. Martijn, and et al. Global microrna profiling of well-differentiated small intestinal neuroendocrine tumors Mod Pathol 26 2013 685 696 doi:610.1038/modpathol.2012.1216. Epub 2013 Jan 1018
    • (2013) Mod Pathol , vol.26 , pp. 685-696
    • Li, S.C.1    Essaghir, A.2    Martijn, C.3
  • 100
    • 82155186923 scopus 로고    scopus 로고
    • The emergence of lncrnas in cancer biology
    • doi:310.1158/2159-8290.CD-1111-0209
    • J.R. Prensner, and A.M. Chinnaiyan The emergence of lncrnas in cancer biology Cancer Discov 1 2011 391 407 doi:310.1158/2159-8290.CD-1111-0209
    • (2011) Cancer Discov , vol.1 , pp. 391-407
    • Prensner, J.R.1    Chinnaiyan, A.M.2


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