In vitro selection of RNA aptamers against CA125 tumor marker in ovarian cancer and its study by optical biosensing

Methods

Volumn 97, Issue , 2016, Pages 58-68

  Lamberti, Ilaria ^a   Scarano, Simona ^c   Esposito, Carla Lucia ^d   Antoccia, Antonio ^a,b   Antonini, Giovanni ^a,b   Tanzarella, Caterina ^a   De Franciscis, Vittorio ^d   Minunni, Maria ^b,c  

^a ROMA TRE UNIVERSITY   (Italy)

^b NATIONAL INSTITUTE OF BIOSTRUCTURES AND BIOSYSTEMS   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

^d CNR   (Italy)

Author keywords

Aptamers; CA125; SELEX; Surface Plasmon Resonance

Indexed keywords

APTAMER; CA 125 ANTIGEN; RNA; RNA APTAMER; UNCLASSIFIED DRUG; IMMOBILIZED PROTEIN; MEMBRANE PROTEIN; MUC16 PROTEIN, HUMAN; PROTEIN BINDING;

ANTIGEN DETECTION; ARTICLE; BINDING AFFINITY; BIOSENSOR; CONTROLLED STUDY; IN VITRO STUDY; LIMIT OF DETECTION; MOLECULAR CLONING; OVARY CANCER; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; PROTEIN PURIFICATION; PROTEIN RNA BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; RNA SEQUENCE; SURFACE PLASMON RESONANCE; CHEMISTRY; EARLY CANCER DIAGNOSIS; FEMALE; GENETIC PROCEDURES; HUMAN; INVERTED REPEAT; OVARIAN NEOPLASMS; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE;

APTAMERS, NUCLEOTIDE; BIOSENSING TECHNIQUES; CA-125 ANTIGEN; EARLY DETECTION OF CANCER; FEMALE; HUMANS; IMMOBILIZED PROTEINS; INVERTED REPEAT SEQUENCES; MEMBRANE PROTEINS; OVARIAN NEOPLASMS; PROTEIN BINDING; SELEX APTAMER TECHNIQUE;

EID: 84959875400     PISSN: 10462023     EISSN: 10959130     Source Type: Journal    
DOI: 10.1016/j.ymeth.2015.10.022     Document Type: Article

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