-
2
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
COI: 1:CAS:528:DC%2BD1MXlsVKhs74%3D, PID: 19269895
-
Stupp R, Hegi ME, Mason WP et al (2009) Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10:459–466
-
(2009)
Lancet Oncol
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
-
3
-
-
80855156702
-
Understanding glioblastoma tumor biology: the potential to improve current diagnosis and treatments
-
PID: 22078644
-
Kesari S (2011) Understanding glioblastoma tumor biology: the potential to improve current diagnosis and treatments. Semin Oncol 38:S2–S10
-
(2011)
Semin Oncol
, vol.38
, pp. 2-10
-
-
Kesari, S.1
-
4
-
-
48249125791
-
Malignant gliomas in adults
-
COI: 1:CAS:528:DC%2BD1cXpt1Sgsrw%3D, PID: 18669428
-
Wen PY, Kesari S (2008) Malignant gliomas in adults. N Engl J Med 359:492–507
-
(2008)
N Engl J Med
, vol.359
, pp. 492-507
-
-
Wen, P.Y.1
Kesari, S.2
-
5
-
-
0037032835
-
The protein kinase complement of the human genome
-
COI: 1:CAS:528:DC%2BD38Xpt1Wisb0%3D, PID: 12471243
-
Manning G, Whyte DB, Martinez R et al (2002) The protein kinase complement of the human genome. Science 298:1912–1934
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
-
6
-
-
79960339454
-
WEE1 kinase targeting combined with DNA-damaging cancer therapy catalyzes mitotic catastrophe
-
PID: 21562035
-
De Witt Hamer PC, Mir SE, Noske D et al (2011) WEE1 kinase targeting combined with DNA-damaging cancer therapy catalyzes mitotic catastrophe. Clin Cancer Res 17:4200–4207
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4200-4207
-
-
De Witt Hamer, P.C.1
Mir, S.E.2
Noske, D.3
-
7
-
-
77956517283
-
In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma
-
COI: 1:CAS:528:DC%2BC3cXhtFGht7bJ, PID: 20832752
-
Mir SE, De Witt Hamer PC, Krawczyk PM et al (2010) In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma. Cancer Cell 18:244–257
-
(2010)
Cancer Cell
, vol.18
, pp. 244-257
-
-
Mir, S.E.1
De Witt Hamer, P.C.2
Krawczyk, P.M.3
-
8
-
-
0035890610
-
Radiosensitization of p53 Mutant Cells by PD0166285, a Novel G2 Checkpoint Abrogator
-
COI: 1:CAS:528:DC%2BD3MXovVShsLs%3D, PID: 11719452
-
Wang Y, Li J, Booher RN et al (2001) Radiosensitization of p53 Mutant Cells by PD0166285, a Novel G2 Checkpoint Abrogator. Cancer Res 61:8211–8217
-
(2001)
Cancer Res
, vol.61
, pp. 8211-8217
-
-
Wang, Y.1
Li, J.2
Booher, R.N.3
-
9
-
-
65249161106
-
Integrated functional, gene expression and genomic analysis for the identification of cancer targets
-
PID: 19357772
-
Iorns E, Lord CJ, Grigoriadis A et al (2009) Integrated functional, gene expression and genomic analysis for the identification of cancer targets. PLoS One 4:e5120
-
(2009)
PLoS One
, vol.4
, pp. 5120
-
-
Iorns, E.1
Lord, C.J.2
Grigoriadis, A.3
-
10
-
-
0037371056
-
Cyclins and cyclin-dependent kinases: comparative study of hepatocellular carcinoma versus cirrhosis
-
COI: 1:CAS:528:DC%2BD3sXit1ylsbs%3D, PID: 12601350
-
Masaki T, Shiratori Y, Rengifo W et al (2003) Cyclins and cyclin-dependent kinases: comparative study of hepatocellular carcinoma versus cirrhosis. Hepatology 37:534–543
-
(2003)
Hepatology
, vol.37
, pp. 534-543
-
-
Masaki, T.1
Shiratori, Y.2
Rengifo, W.3
-
11
-
-
47349092050
-
Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis
-
PID: 18416826
-
Blenk S, Engelmann JC, Pinkert MWS et al (2008) Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis. BMC Cancer 8:106
-
(2008)
BMC Cancer
, vol.8
, pp. 106
-
-
Blenk, S.1
Engelmann, J.C.2
Pinkert, M.W.S.3
-
12
-
-
84870459187
-
A population-based study of high-grade gliomas and mutated isocitrate dehydrogenase 1
-
COI: 1:CAS:528:DC%2BC3sXivFGit7Y%3D, PID: 23236540
-
Dahlrot RH, Kristensen BW, Hjelmborg J et al (2013) A population-based study of high-grade gliomas and mutated isocitrate dehydrogenase 1. Int J Clin Exp Pathol 6:31–40
-
(2013)
Int J Clin Exp Pathol
, vol.6
, pp. 31-40
-
-
Dahlrot, R.H.1
Kristensen, B.W.2
Hjelmborg, J.3
-
13
-
-
84883156247
-
A population-based study of low-grade gliomas and mutated isocitrate dehydrogenase 1 (IDH1)
-
COI: 1:CAS:528:DC%2BC3sXhtlSiurzI, PID: 23817809
-
Dahlrot RH, Kristensen BW, Hjelmborg J et al (2013) A population-based study of low-grade gliomas and mutated isocitrate dehydrogenase 1 (IDH1). J Neurooncol 114:309–317
-
(2013)
J Neurooncol
, vol.114
, pp. 309-317
-
-
Dahlrot, R.H.1
Kristensen, B.W.2
Hjelmborg, J.3
-
14
-
-
84871787992
-
MiR-21 expression in the tumor cell compartment holds unfavorable prognostic value in gliomas
-
COI: 1:CAS:528:DC%2BC38XhvFSgtLvK, PID: 23104517
-
Hermansen SK, Dahlrot RH, Nielsen BS et al (2013) MiR-21 expression in the tumor cell compartment holds unfavorable prognostic value in gliomas. J Neurooncol 111(1):71–81
-
(2013)
J Neurooncol
, vol.111
, Issue.1
, pp. 71-81
-
-
Hermansen, S.K.1
Dahlrot, R.H.2
Nielsen, B.S.3
-
15
-
-
84890303143
-
Prognostic value of Musashi-1 in gliomas
-
COI: 1:CAS:528:DC%2BC3sXhsV2ksb%2FP, PID: 24057325
-
Dahlrot RH, Hansen S, Herrstedt J et al (2013) Prognostic value of Musashi-1 in gliomas. J Neurooncol 115:453–461
-
(2013)
J Neurooncol
, vol.115
, pp. 453-461
-
-
Dahlrot, R.H.1
Hansen, S.2
Herrstedt, J.3
-
16
-
-
84892509068
-
High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor
-
COI: 1:CAS:528:DC%2BC2cXmtl2h, PID: 24373972
-
Lathia JD, Li M, Sinyuk M (2014) High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor. Cell Rep 6(1):117–129
-
(2014)
Cell Rep
, vol.6
, Issue.1
, pp. 117-129
-
-
Lathia, J.D.1
Li, M.2
Sinyuk, M.3
-
17
-
-
84906255620
-
Clinical value of CD133 and nestin in patients with glioma: a population-based study
-
PID: 25120750
-
Dahlrot RH, Hansen S, Jensen SS et al (2014) Clinical value of CD133 and nestin in patients with glioma: a population-based study. Int J Clin Exp Pathol 7(7):3739–3751
-
(2014)
Int J Clin Exp Pathol
, vol.7
, Issue.7
, pp. 3739-3751
-
-
Dahlrot, R.H.1
Hansen, S.2
Jensen, S.S.3
-
18
-
-
79955402190
-
WEE1 inhibition sensitizes osteosarcoma to radiotherapy
-
COI: 1:CAS:528:DC%2BC3MXlslGmtr4%3D, PID: 21529352
-
PosthumaDeBoer J, Wurdinger T, Graat H et al (2011) WEE1 inhibition sensitizes osteosarcoma to radiotherapy. BMC Cancer 11:156
-
(2011)
BMC Cancer
, vol.11
, pp. 156
-
-
PosthumaDeBoer, J.1
Wurdinger, T.2
Graat, H.3
-
19
-
-
84894228414
-
Targeting Wee1 for the treatment of pediatric high-grade gliomas
-
PID: 24305702
-
Mueller S, Hashizume R, Yang X et al (2013) Targeting Wee1 for the treatment of pediatric high-grade gliomas. Neuro-Oncology 16(3):352–360
-
(2013)
Neuro-Oncology
, vol.16
, Issue.3
, pp. 352-360
-
-
Mueller, S.1
Hashizume, R.2
Yang, X.3
-
20
-
-
84897951005
-
Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma
-
Harris PS, Venkataraman S, Alimova I et al (2014) Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma. Mol Cancer 13:1–14
-
(2014)
Mol Cancer
, vol.13
, pp. 1-14
-
-
Harris, P.S.1
Venkataraman, S.2
Alimova, I.3
-
21
-
-
84855247875
-
Hypoxia induces WEE1 expression and attenuates hydrogen peroxide-induced endothelial damage in MS1 cells
-
COI: 1:CAS:528:DC%2BC38XktleisA%3D%3D, PID: 21918363
-
Hong KS, Kim HS, Kim SH et al (2011) Hypoxia induces WEE1 expression and attenuates hydrogen peroxide-induced endothelial damage in MS1 cells. Exp Mol Med 43:653–659
-
(2011)
Exp Mol Med
, vol.43
, pp. 653-659
-
-
Hong, K.S.1
Kim, H.S.2
Kim, S.H.3
-
22
-
-
1342267616
-
The clinical significance of cyclin B1 and Wee1 expression in non-small-cell lung cancer
-
COI: 1:STN:280:DC%2BD2c%2FlvVamsQ%3D%3D, PID: 14760118
-
Yoshida T, Tanaka S, Mogi A et al (2004) The clinical significance of cyclin B1 and Wee1 expression in non-small-cell lung cancer. Ann Oncol 15:252–256
-
(2004)
Ann Oncol
, vol.15
, pp. 252-256
-
-
Yoshida, T.1
Tanaka, S.2
Mogi, A.3
-
23
-
-
84882253419
-
Preclinical evaluation of the WEE1 inhibitor MK-1775 as single-agent anticancer therapy
-
COI: 1:CAS:528:DC%2BC3sXht1ChurzF, PID: 23699655
-
Guertin AD, Li J, Liu Y et al (2013) Preclinical evaluation of the WEE1 inhibitor MK-1775 as single-agent anticancer therapy. Mol Cancer Ther 12:1442–1452
-
(2013)
Mol Cancer Ther
, vol.12
, pp. 1442-1452
-
-
Guertin, A.D.1
Li, J.2
Liu, Y.3
-
24
-
-
84855645086
-
MK1775, a selective Wee1 inhibitor, shows single-agent antitumor activity against sarcoma cells
-
PID: 22084170
-
Kreahling JM, Gemmer JY, Reed D et al (2011) MK1775, a selective Wee1 inhibitor, shows single-agent antitumor activity against sarcoma cells. Mol Cancer Ther 11(1):174–182
-
(2011)
Mol Cancer Ther
, vol.11
, Issue.1
, pp. 174-182
-
-
Kreahling, J.M.1
Gemmer, J.Y.2
Reed, D.3
-
25
-
-
83355174034
-
Targeting radiation-induced G2 checkpoint activation with the Wee-1 inhibitor MK-1775 in glioblastoma cell lines
-
COI: 1:CAS:528:DC%2BC3MXhsFylurfP, PID: 21992793
-
Sarcar B, Kahali S, Prabhu AH et al (2011) Targeting radiation-induced G2 checkpoint activation with the Wee-1 inhibitor MK-1775 in glioblastoma cell lines. Mol Cancer Ther 10(12):2405–2414
-
(2011)
Mol Cancer Ther
, vol.10
, Issue.12
, pp. 2405-2414
-
-
Sarcar, B.1
Kahali, S.2
Prabhu, A.H.3
-
26
-
-
84959874747
-
-
Cancer Incidence by Age. Cancer Research UK. Accessed 26 Nov 2014
-
Cancer Incidence by Age. Cancer Research UK. http://www.cancerresearchuk.org/cancer-info/cancerstats/incidence/age/. Accessed 26 Nov 2014
-
-
-
-
27
-
-
84959900513
-
-
Do Cancer Rates Differ with Age? Australian Institute of Health and Welfare. Accessed 26 Nov 2014
-
Do Cancer Rates Differ with Age? Australian Institute of Health and Welfare http://www.aihw.gov.au/cancer/. Accessed 26 Nov 2014
-
-
-
-
28
-
-
34547941973
-
The common biology of cancer and ageing
-
COI: 1:CAS:528:DC%2BD2sXptVGrs70%3D, PID: 17700693
-
Finkel T, Serrano M, Blasco MA (2007) The common biology of cancer and ageing. Nature 448:767–774
-
(2007)
Nature
, vol.448
, pp. 767-774
-
-
Finkel, T.1
Serrano, M.2
Blasco, M.A.3
-
29
-
-
20344407807
-
Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas
-
COI: 1:CAS:528:DC%2BD2MXlvVSgsbg%3D, PID: 15977639
-
Ohgaki H, Kleihues P (2005) Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas. J Neuropathol Exp Neurol 64:479–489
-
(2005)
J Neuropathol Exp Neurol
, vol.64
, pp. 479-489
-
-
Ohgaki, H.1
Kleihues, P.2
-
30
-
-
84922513709
-
TERT promoter mutations: a novel independent prognostic factor in primary glioblastomas
-
PID: 25140036
-
Simon M, Hosen I, Gousias K et al (2015) TERT promoter mutations: a novel independent prognostic factor in primary glioblastomas. Neuro-Oncology 17:45–52
-
(2015)
Neuro-Oncology
, vol.17
, pp. 45-52
-
-
Simon, M.1
Hosen, I.2
Gousias, K.3
-
31
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
COI: 1:CAS:528:DC%2BD2MXit1Wktro%3D, PID: 15758010
-
Hegi ME, Diserens AC, Gorlia T et al (2005) MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352(10):997–1003
-
(2005)
N Engl J Med
, vol.352
, Issue.10
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
|