Disrupted short chain specific β-oxidation and improved synthase expression increase synthesis of short chain fatty acids in Saccharomyces cerevisiae

Biotechnology and Bioengineering

Volumn 113, Issue 4, 2016, Pages 895-900

  Leber, Christopher ^a   Choi, Jin Wook ^a   Polson, Brian ^a   Da Silva, Nancy A ^a  

^a University of California at Irvine   (United States)

Author keywords

Biorenewable chemicals; Homo sapiens fatty acid synthase; Saccharomyces cerevisiae; Short chain fatty acids; oxidation

Indexed keywords

BIOCHEMICAL ENGINEERING; BIODIVERSITY; CHAINS; ENZYMES; METABOLIC ENGINEERING; METABOLISM; OXIDATION; SATURATED FATTY ACIDS; SYNTHESIS (CHEMICAL); YEAST;

BETA OXIDATION; BIORENEWABLE; CHEMICAL PRECURSORS; FATTY ACID SYNTHASE; OCTANOIC ACIDS; PETROLEUM-DERIVED FUELS; SHORT-CHAIN FATTY ACIDS; SYNTHASE EXPRESSION;

FATTY ACIDS;

ACETYL COENZYME A; ACYL COENZYME A DEHYDROGENASE; DECANOIC ACID; FATTY ACID SYNTHASE; HEXANOIC ACID; OCTANOIC ACID; PHOSPHOPANTETHEINE TRANSFERASE; THIOL ESTER HYDROLASE; TRANSFERASE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; PALMITOYL COENZYME A HYDROLASE; PHOSPHOPANTETHEINYL TRANSFERASE; PHOSPHOTRANSFERASE; VOLATILE FATTY ACID;

ARTICLE; CITRIC ACID CYCLE; CODON USAGE; CYTOSOL; ENZYME ACTIVATION; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; GENE DELETION; HUMAN; METABOLIC ENGINEERING; NONHUMAN; PEROXISOME; PROMOTER REGION; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; GENETICS; METABOLISM; OXIDATION REDUCTION REACTION; PROCEDURES; TRANSGENE;

BACTERIAL PROTEINS; FATTY ACIDS, VOLATILE; GENE DELETION; HUMANS; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; OXIDATION-REDUCTION; PALMITOYL-COA HYDROLASE; SACCHAROMYCES CEREVISIAE; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS); TRANSGENES;

EID: 84959536640     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25839     Document Type: Article

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