Targeted radiotherapy enhancement during electronic brachytherapy of accelerated partial breast irradiation (APBI) using controlled release of gold nanoparticles

Physica Medica

Volumn 31, Issue 8, 2015, Pages 1070-1074

  Cifter, G ^a,b   Chin, J ^a   Cifter, F ^b   Altundal, Y ^a   Sinha, N ^c   Sajo, E ^a   Ngwa, W ^a,b  

^a UNIVERSITY OF MASSACHUSETTS LOWELL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c WENTWORTH INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

50 kVp; APBI; Dose enhancement; Gold; Nanoparticles; Xoft electronic brachytherapy

Indexed keywords

GOLD NANOPARTICLE; POLYMER; DELAYED RELEASE FORMULATION; GOLD; METAL NANOPARTICLE; RADIOSENSITIZING AGENT;

ACCELERATED PARTIAL BREAST IRRADIATION; ANALYTIC METHOD; ARTICLE; BRACHYTHERAPY; BRACHYTHERAPY DEVICE; CANCER RADIOTHERAPY; CONTROLLED RELEASE FORMULATION; DIFFUSION COEFFICIENT; DOSIMETRY; EXPERIMENTAL STUDY; FEASIBILITY STUDY; IN VIVO STUDY; PARTIAL MASTECTOMY; PARTICLE SIZE; RADIATION DOSE DISTRIBUTION; RADIOLOGICAL PROCEDURES; SURFACE PROPERTY; TREATMENT PLANNING; TREATMENT RESPONSE; BREAST; BREAST NEOPLASMS; CHEMISTRY; DELAYED RELEASE FORMULATION; DEVICES; DRUG EFFECTS; ELECTRICAL EQUIPMENT; HUMAN; RADIATION RESPONSE; RADIOMETRY; RADIOTHERAPY DOSAGE;

BRACHYTHERAPY; BREAST; BREAST NEOPLASMS; DELAYED-ACTION PREPARATIONS; ELECTRICAL EQUIPMENT AND SUPPLIES; FEASIBILITY STUDIES; GOLD; HUMANS; METAL NANOPARTICLES; RADIATION-SENSITIZING AGENTS; RADIOMETRY; RADIOTHERAPY DOSAGE;

EID: 84959531528     PISSN: 11201797     EISSN: 1724191X     Source Type: Journal    
DOI: 10.1016/j.ejmp.2015.07.138     Document Type: Article

References (25)

1. Fisher B., Anderson S., Bryant J., Margolese R.G., Deutsch M., Fisher E.R., et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med 2002, 347:1233-1241.
2. Jagsi R., Haffty B.G. External-beam accelerated partial-breast irradiation: exploring the limits of tolerability. J Clin Oncol 2013, 31:4029-4031.
3. Lori L., Vanyo M.D. Accelerated Partial Breast Irradiation (APBI) 2009, The Robert and Beverly Lewis Family Cancer Care Center.
4. Ivanov O., Dickler A., Lum B.Y., Pellicane J.V., Francescatti D.S. Twelve-month follow-up results of a trial utilizing Axxent electronic brachytherapy to deliver intraoperative radiation therapy for early-stage breast cancer. Ann Surg Oncol 2011, 18:453-458.
5. Dickler A., Ivanov O., Francescatti D. Intraoperative radiation therapy in the treatment of early-stage breast cancer utilizing xoft axxent electronic brachytherapy. World J Surg Oncol 2009, 7:24.
6. Wazer D.E., Kaufman S., Cuttino L., DiPetrillo T., Arthur D.W. Accelerated partial breast irradiation: an analysis of variables associated with late toxicity and long-term cosmetic outcome after high-dose-rate interstitial brachytherapy. Int J Radiat Oncol Biol Phys 2006, 64:489-495.
7. Alkilany A.M., Murphy C.J. Toxicity and cellular uptake of gold nanoparticles: what we have learned so far?. J Nanopart Res 2010, 12:2313-2333.
8. Smith G.L., Xu Y., Buchholz T.A., Giordano S.H., Jiang J., Shih Y.C., et al. Association between treatment with brachytherapy vs whole-breast irradiation and subsequent mastectomy, complications, and survival among older women with invasive breast cancer. JAMA 2012, 307:1827-1837.
9. Ngwa W., Kumar R., Sridhar S., Korideck H., Zygmanski P., Cormack R.A., et al. Targeted radiotherapy with gold nanoparticles: current status and future perspectives. Nanomedicine (Lond) 2014, 9:1063-1082.
10. Liu Y., Liu X., Jin X., He P., Zheng X., Dai Z., et al. The dependence of radiation enhancement effect on the concentration of gold nanoparticles exposed to low- and high-LET radiations. Phys Med 2015, 31:210-218.
11. Gehrke C., Oates R., Ramachandran P., Deloar H.M., Gill S., Kron T. Automatic tracking of gold seed markers from CBCT image projections in lung and prostate radiotherapy. Phys Med 2015, 31:185-191.
12. Grant S.A., Spradling C.S., Grant D.N., Fox D.B., Jimenez L., Grant D.A., et al. Assessment of the biocompatibility and stability of a gold nanoparticle collagen bioscaffold. J Biomed Mater Res A 2014, 102:332-339.
13. Elbialy N.S., Fathy M.M., Khalil W.M. Preparation and characterization of magnetic gold nanoparticles to be used as doxorubicin nanocarriers. Phys Med 2014, 30:843-848.
14. Park C.C., Yom S.S., Podgorsak M.B., Harris E., Price R.A., Bevan A., et al. American Society for Therapeutic Radiology and Oncology (ASTRO) Emerging Technology Committee report on electronic brachytherapy. Int J Radiat Oncol Biol Phys 2010, 76:963-972.
15. Poludniowski G., Landry G., DeBlois F., Evans P.M., Verhaegen F. SpekCalc: a program to calculate photon spectra from tungsten anode x-ray tubes. Phys Med Biol 2009, 54:N433-8.
16. Wong C., Stylianopoulos T., Cui J., Martin J., Chauhan V.P., Jiang W., et al. Multistage nanoparticle delivery system for deep penetration into tumor tissue. Proc Natl Acad Sci U S A 2011, 108(6):2426-2431.
17. Cho S.H., Jones B.L., Krishnan S. The dosimetric feasibility of gold nanoparticle-aided radiation therapy (GNRT) via brachytherapy using low-energy gamma-/x-ray sources. Phys Med Biol 2009, 54:4889-4905.
18. FDA-Database accessed 03.14. http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018057s080lbl.pdf.
19. Ngwa W., Makrigiorgos G.M., Berbeco R.I. Gold nanoparticle-aided brachytherapy with vascular dose painting: estimation of dose enhancement to the tumor endothelial cell nucleus. Med Phys 2012, 39:392-398.
20. Sinha N., Cifter G., Sajo E., Kumar R., Sridhar S., Nguyen P.L., et al. Brachytherapy application with in situ dose painting administered by gold nanoparticle eluters. Int J Radiat Oncol Biol Phys 2015, 91(2):385-392.
21. Cole A. Absorption of 20-eV to 50,000-eV electron beams in air and plastic. Radiat Res 1969, 38:7-33.
22. Sanders M.E., Scroggins T., Ampil F.L., Li B.D. Accelerated partial breast irradiation in early-stage breast cancer. J Clin Oncol 2007, 25:996-1002.
23. Kuban D.A., Levy L.B., Cheung M.R., Lee A.K., Choi S., Frank S., et al. Long-term failure patterns and survival in a randomized dose-escalation trial for prostate cancer. Who dies of disease?. Int J Radiat Oncol Biol Phys 2011, 79:1310-1317.
24. Berbeco R.I., Ngwa W., Makrigiorgos G.M. Localized dose enhancement to tumor blood vessel endothelial cells via megavoltage X-rays and targeted gold nanoparticles: new potential for external beam radiotherapy. Int J Radiat Oncol Biol Phys 2011, 81:270-276.
25. Yang C., Uertz J., Yohan D., Chithrani B.D. Peptide modified gold nanoparticles for improved cellular uptake, nuclear transport, and intracellular retention. Nanoscale 2014, 6:12026-12033.