Localized dose enhancement to tumor blood vessel endothelial cells via megavoltage X-rays and targeted gold nanoparticles: New potential for external beam radiotherapy

International Journal of Radiation Oncology Biology Physics

Volumn 81, Issue 1, 2011, Pages 270-276

  Berbeco, Ross I ^a   Ngwa, Wilfred ^a   Makrigiorgos, G Mike ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Anti angiogenesis; Nanoparticles; SBRT

Indexed keywords

ANALYTIC METHOD; ANTI-ANGIOGENESIS; CENTRAL AXIS; DOSE ENHANCEMENT FACTORS; ENERGY FLUENCES; EXTERNAL BEAM; EXTERNAL BEAM RADIOTHERAPY; GOLD NANOPARTICLE; GOLD NANOPARTICLES; INTRAVASCULAR; LOW ENERGIES; MEGAVOLTAGE; MICRO-DOSIMETRY; MULTIPLE POINTS; ORGANS AT RISKS; SBRT; SINGLE-CELL LEVEL; TARGET VOLUMES; THERAPEUTIC DOSE; THIN SLAB; TUMOR MICROVASCULATURE; X RAY IRRADIATION; X RAY SPECTRUM;

BLOOD; BLOOD VESSELS; LINEAR ACCELERATORS; NANOPARTICLES; PHOTOELECTRON SPECTROSCOPY; PHOTONS; RADIOTHERAPY; SLAB MILLS; TUMORS; X RAYS;

ENDOTHELIAL CELLS;

GOLD NANOPARTICLE;

ARTICLE; CLINICAL EFFECTIVENESS; ENDOTHELIUM CELL; EXTERNAL BEAM RADIOTHERAPY; IN VIVO STUDY; MEGAVOLTAGE RADIOTHERAPY; MICRODOSIMETRY; PRIORITY JOURNAL; RADIATION DOSE; RADIATION ENERGY; TUMOR VASCULARIZATION;

ALGORITHMS; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GOLD; METAL NANOPARTICLES; MICROCIRCULATION; MONTE CARLO METHOD; NEOPLASMS; PARTICLE ACCELERATORS; PHOTONS; RADIOTHERAPY; RADIOTHERAPY DOSAGE;

EID: 79961128562     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.10.022     Document Type: Article

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