Long-term failure patterns and survival in a randomized dose-escalation trial for prostate cancer. Who dies of disease?

International Journal of Radiation Oncology Biology Physics

Volumn 79, Issue 5, 2011, Pages 1310-1317

  Kuban, Deborah A ^a   Levy, Lawrence B ^a   Cheung, M Rex ^a   Lee, Andrew K ^a   Choi, Seungtaek ^a   Frank, Steven ^a   Pollack, Alan ^b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Dose escalation; Failure patterns; Prostate cancer; Radiotherapy; Survival

Indexed keywords

CLINICAL FAILURE; CUMULATIVE INCIDENCE; DOSE ESCALATION; DOSE LEVELS; FAILURE PATTERNS; GLEASON SCORES; PRE-TREATMENT; PREDICTIVE FACTORS; PROSTATE CANCER; PROSTATE CANCERS; PROSTATE SPECIFIC ANTIGEN; SURVIVAL;

RADIOTHERAPY; REGRESSION ANALYSIS;

DISEASES;

PROSTATE SPECIFIC ANTIGEN;

AGE; AGED; ARTICLE; CANCER MORTALITY; CANCER RECURRENCE; CANCER SURVIVAL; CAUSE OF DEATH; CONTROLLED STUDY; EXTERNAL BEAM RADIOTHERAPY; GLEASON SCORE; HUMAN; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION DOSE; RANDOMIZED CONTROLLED TRIAL; TREATMENT FAILURE; TUMOR GROWTH;

AGE FACTORS; AGED; CAUSE OF DEATH; FOLLOW-UP STUDIES; HUMANS; MALE; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; RADIOTHERAPY DOSAGE; REGRESSION ANALYSIS; TIME FACTORS;

EID: 79952701542     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.01.006     Document Type: Article

References (16)

1. American Joint Commission on Cancer. AJCC Cancer Staging Manual. 4th ed. Philadelphia, PA: Lippincott-Raven; 1992.
2. Pollack A, Zagars GK, Starkschall G, et al. Prostate cancer radiation dose response: Results of the M.D. Anderson Phase III randomized trial. Int J Radiat Oncol Biol Phys 2002;53:1097-1105. (Pubitemid 34787842)
3. Kuban DA, Tucker S, Dong L, et al. Long-term results of the M.D. Anderson Randomized Dose-Escalation Trial for Prostate Cancer. Int J Rad Oncol Biol Phys 2008;70:67-74. (Pubitemid 350251041)
4. Scardino P. Update: NCCN Prostate Cancer Clinical Practice Guidelines. J Natl Comp Canc Netw 2005;3(Suppl 1):S29-S33.
5. American Society for Therapeutic Radiology, and Oncology Consensus Panel. Consensus Statement: Guidelines for PSA following Radiation Therapy. Int J Radiat Oncol Biol Phys 1997;37:1035-1041.
6. Roach M, Hanks G, Thames H, et al. Defining biochemical failure following radiotherapy with or without hormonal therapy in men with clinically localized prostate cancer: Recommendations of the RTOG-ASTRO Phoenix Consensus Conference. Int J Radiat Oncol Biol Phys 2006;65:965-974.
7. Hakulinen T, Abeywickrama KH.A computer program package for relative survival analysis. Comp Progr Biomed 1985;19:197-207. (Pubitemid 15098487)
8. Pollack A, Smith LG, von Eschenbach AC. External beam radiotherapy dose-response characteristics of 1127 men with prostate cancer treated in the PSA era. Int J Radiat Oncol Biol Phys 2000;48:507-512.
9. Hanks Ge, Hanlon AL, Epstein B, Horwitz EM. Dose response in prostate cancer with 8-12 years' follow-up. Int J Radiat Oncol Biol Phys 2002;54:427-435. (Pubitemid 35286808)
10. Hanks GE, Martz KL, Diamond JJ. The effect of dose on local control of prostate cancer. Int J Radiat Oncol Biol Phys 1988;15:1299-1305. (Pubitemid 19015470)
11. Zietman AL, DeSilvio ML, Slater JD, et al. Comparison of conventional-dose vs high-dose conformal radiation therapy in localized adenocarcinoma of the prostate. JAMA 2005;294:1233-1239. (Pubitemid 41352111)
12. Zietman AL. Correction: Inaccurate analysis and results in a study of radiation therapy in adenocarcinoma of the prostate. JAMA 2008;299:898-899. (Pubitemid 351397078)
13. Zefelsky MJ, Yamada Y, Fuks Z, et al. Long-term results of conformal radiotherapy for prostate cancer: Impact dose escalation on biochemical tumor control and distant metastases-free survival outcomes. Int J Radiat Oncol Biol Phys 2008;72:1028-1033.
14. Lu-Yao G, Stukel TA, Yao SL. Changing patterns in competing causes of death in men with prostate cancer: A population based study. J Urol 2004;171:2285-2290. (Pubitemid 38625453)
15. Chandra A, Dong L, Huang E, et al. Experience of ultrasound-based daily prostate localization. Int J Radiat Oncol Biol Phys 2003;56:436-447. (Pubitemid 36546257)
16. Zefelsky MJ, Chan H, Hunt M, et al. Long-term outcome of high dose intensity modulated radiation therapy for patients with clinically localized prostate cancer. J Urol 2006;176:1415-1419. (Pubitemid 44307191)