Development of potential broad spectrum antimicrobials using C2-symmetric 9-fluorenone alkyl amine

Bioorganic and Medicinal Chemistry Letters

Volumn 26, Issue 8, 2016, Pages 1997-1999

  Choi, Seoung Ryoung ^a   Larson, Marilynn A ^a   Hinrichs, Steven H ^a   Narayanasamy, Prabagaran ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

9 Fluorenone; Bacillus anthracis; Bacterial primase; Staphylococcus aureus; Tilorone

Indexed keywords

9 FLUORENONE DERIVATIVE; ANTIINFECTIVE AGENT; FLUORENONE DERIVATIVE; TILORONE; UNCLASSIFIED DRUG; DNA PRIMASE; ENZYME INHIBITOR; FLUORENE DERIVATIVE;

ARTICLE; BACILLUS ANTHRACIS; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BURKHOLDERIA THAILANDENSIS; DRUG SYNTHESIS; FRANCISELLA TULARENSIS; GROWTH INHIBITION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; ANTAGONISTS AND INHIBITORS; BACTERIUM; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; HIGH THROUGHPUT SCREENING; METABOLISM; MICROBIAL SENSITIVITY TEST; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTI-BACTERIAL AGENTS; BACTERIA; DNA PRIMASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FLUORENES; HIGH-THROUGHPUT SCREENING ASSAYS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84959528648     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2016.02.087     Document Type: Article

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