-
2
-
-
84918519117
-
Bevacizumab combined with chemotherapy for platinum-resistant recurrent ovarian cancer: the AURELIA open-label randomized phase III trial
-
This randomized phase 3 trail combined bevacizumab /single agent chemotherapy in platinunm refractory ovarian cancer patients and showed a significantly extended PFS compared to chemotherapy alone.
-
Pujade-Lauraine E et al. Bevacizumab combined with chemotherapy for platinum-resistant recurrent ovarian cancer: the AURELIA open-label randomized phase III trial. J Clin Oncol. 2014;32(13):302–8. This randomized phase 3 trail combined bevacizumab /single agent chemotherapy in platinunm refractory ovarian cancer patients and showed a significantly extended PFS compared to chemotherapy alone.
-
(2014)
J Clin Oncol
, vol.32
, Issue.13
, pp. 302-308
-
-
Pujade-Lauraine, E.1
-
3
-
-
0037448353
-
Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer
-
COI: 1:CAS:528:DC%2BD3sXksVehug%3D%3D, PID: 12529460, This study showed that the presence of intratumoral T cells in patients with advanced ovarian cancer correlated with improved clinical outcome
-
Zhang L et al. Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer. N Engl J Med. 2003;348(3):203–13. This study showed that the presence of intratumoral T cells in patients with advanced ovarian cancer correlated with improved clinical outcome.
-
(2003)
N Engl J Med
, vol.348
, Issue.3
, pp. 203-213
-
-
Zhang, L.1
-
4
-
-
81555228400
-
Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells
-
COI: 1:CAS:528:DC%2BC3MXhsFyqtr%2FO, PID: 21972293
-
Obermajer N et al. Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells. Blood. 2011;118(20):5498–505.
-
(2011)
Blood
, vol.118
, Issue.20
, pp. 5498-5505
-
-
Obermajer, N.1
-
5
-
-
84255170450
-
PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment
-
COI: 1:CAS:528:DC%2BC3MXhs1agtrrM, PID: 22025564
-
Obermajer N et al. PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment. Cancer Res. 2011;71(24):7463–70.
-
(2011)
Cancer Res
, vol.71
, Issue.24
, pp. 7463-7470
-
-
Obermajer, N.1
-
6
-
-
84872872011
-
Dynamics of T-cell infiltration during the course of ovarian cancer: the gradual shift from a Th17 effector cell response to a predominant infiltration by regulatory T-cells
-
COI: 1:CAS:528:DC%2BC38Xht1Ciur3O, PID: 22865582
-
Fialova A et al. Dynamics of T-cell infiltration during the course of ovarian cancer: the gradual shift from a Th17 effector cell response to a predominant infiltration by regulatory T-cells. Int J Cancer. 2013;132(5):1070–9.
-
(2013)
Int J Cancer
, vol.132
, Issue.5
, pp. 1070-1079
-
-
Fialova, A.1
-
7
-
-
84882609015
-
Impaired Th1 immunity in ovarian cancer patients is mediated by TNFR2+ Tregs within the tumor microenvironment
-
COI: 1:CAS:528:DC%2BC3sXhsVOkurbN, PID: 23948613
-
Govindaraj C et al. Impaired Th1 immunity in ovarian cancer patients is mediated by TNFR2+ Tregs within the tumor microenvironment. Clin Immunol. 2013;149(1):97–110.
-
(2013)
Clin Immunol
, vol.149
, Issue.1
, pp. 97-110
-
-
Govindaraj, C.1
-
8
-
-
84893573894
-
The ratios of CD8+ T cells to CD4 + CD25+ FOXP3+ and FOXP3- T cells correlate with poor clinical outcome in human serous ovarian cancer
-
PID: 24244610
-
Preston CC et al. The ratios of CD8+ T cells to CD4 + CD25+ FOXP3+ and FOXP3- T cells correlate with poor clinical outcome in human serous ovarian cancer. PLoS One. 2013;8(11):e80063.
-
(2013)
PLoS One
, vol.8
, Issue.11
, pp. e80063
-
-
Preston, C.C.1
-
9
-
-
84875171283
-
PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction
-
COI: 1:CAS:528:DC%2BC3sXktFKksLY%3D, PID: 23340297
-
Abiko K et al. PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction. Clin Cancer Res. 2013;19(6):1363–74.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.6
, pp. 1363-1374
-
-
Abiko, K.1
-
10
-
-
84938599283
-
Immunotherapy approaches in cancer treatment
-
COI: 1:CAS:528:DC%2BC2MXht1OmsLnF, PID: 26087990
-
Klener Jr P et al. Immunotherapy approaches in cancer treatment. Curr Pharm Biotechnol. 2015;16(9):771–81.
-
(2015)
Curr Pharm Biotechnol
, vol.16
, Issue.9
, pp. 771-781
-
-
Klener, P.1
-
11
-
-
0036605567
-
Generation of T-cell immunity to the HER-2/neu protein after active immunization with HER-2/neu peptide-based vaccines
-
COI: 1:CAS:528:DC%2BD38XkvF2mtr8%3D, PID: 12039923
-
Disis ML et al. Generation of T-cell immunity to the HER-2/neu protein after active immunization with HER-2/neu peptide-based vaccines. J Clin Oncol. 2002;20(11):2624–32.
-
(2002)
J Clin Oncol
, vol.20
, Issue.11
, pp. 2624-2632
-
-
Disis, M.L.1
-
12
-
-
34547915603
-
Vaccination with an NY-ESO-1 peptide of HLA class I/II specificities induces integrated humoral and T cell responses in ovarian cancer
-
COI: 1:CAS:528:DC%2BD2sXptVejtLo%3D, PID: 17652518
-
Odunsi K et al. Vaccination with an NY-ESO-1 peptide of HLA class I/II specificities induces integrated humoral and T cell responses in ovarian cancer. Proc Natl Acad Sci U S A. 2007;104(31):12837–42.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.31
, pp. 12837-12842
-
-
Odunsi, K.1
-
13
-
-
84870359509
-
Phase I trial of overlapping long peptides from a tumor self-antigen and poly-ICLC shows rapid induction of integrated immune response in ovarian cancer patients
-
COI: 1:CAS:528:DC%2BC38XhslKgurnM, PID: 23032745
-
Sabbatini P et al. Phase I trial of overlapping long peptides from a tumor self-antigen and poly-ICLC shows rapid induction of integrated immune response in ovarian cancer patients. Clin Cancer Res. 2012;18(23):6497–508.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.23
, pp. 6497-6508
-
-
Sabbatini, P.1
-
14
-
-
84901301005
-
Feasibility study of personalized peptide vaccination for recurrent ovarian cancer patients
-
COI: 1:CAS:528:DC%2BC2cXoslOrurY%3D, PID: 24773550
-
Kawano K et al. Feasibility study of personalized peptide vaccination for recurrent ovarian cancer patients. Immunopharmacol Immunotoxicol. 2014;36(3):224–36.
-
(2014)
Immunopharmacol Immunotoxicol
, vol.36
, Issue.3
, pp. 224-236
-
-
Kawano, K.1
-
15
-
-
84878265563
-
Potentiation of a p53-SLP vaccine by cyclophosphamide in ovarian cancer: a single-arm phase II study
-
Vermeij R et al. Potentiation of a p53-SLP vaccine by cyclophosphamide in ovarian cancer: a single-arm phase II study. Int J Cancer. 2011.
-
(2011)
Int J Cancer
-
-
Vermeij, R.1
-
16
-
-
70350435441
-
Concurrent trastuzumab and HER2/neu-specific vaccination in patients with metastatic breast cancer
-
COI: 1:CAS:528:DC%2BD1MXhtlGgtbnK, PID: 19720923
-
Disis ML et al. Concurrent trastuzumab and HER2/neu-specific vaccination in patients with metastatic breast cancer. J Clin Oncol. 2009;27(28):4685–92.
-
(2009)
J Clin Oncol
, vol.27
, Issue.28
, pp. 4685-4692
-
-
Disis, M.L.1
-
17
-
-
0034331218
-
Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells
-
COI: 1:CAS:528:DC%2BD3cXnslGnt7w%3D, PID: 11049990
-
Brossart P et al. Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells. Blood. 2000;96(9):3102–8.
-
(2000)
Blood
, vol.96
, Issue.9
, pp. 3102-3108
-
-
Brossart, P.1
-
18
-
-
0036181959
-
Vaccination with autologous tumour antigen-pulsed dendritic cells in advanced gynaecological malignancies: clinical and immunological evaluation of a phase I trial
-
COI: 1:CAS:528:DC%2BD38XjsVCns74%3D, PID: 11845259
-
Hernando JJ et al. Vaccination with autologous tumour antigen-pulsed dendritic cells in advanced gynaecological malignancies: clinical and immunological evaluation of a phase I trial. Cancer Immunol Immunother. 2002;51(1):45–52.
-
(2002)
Cancer Immunol Immunother
, vol.51
, Issue.1
, pp. 45-52
-
-
Hernando, J.J.1
-
19
-
-
70349456786
-
A phase I trial of immunotherapy with lapuleucel-T (APC8024) in patients with refractory metastatic tumors that express HER-2/neu
-
COI: 1:CAS:528:DC%2BD1MXhtFars7vM, PID: 19723649
-
Peethambaram PP et al. A phase I trial of immunotherapy with lapuleucel-T (APC8024) in patients with refractory metastatic tumors that express HER-2/neu. Clin Cancer Res. 2009;15(18):5937–44.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.18
, pp. 5937-5944
-
-
Peethambaram, P.P.1
-
20
-
-
84900541220
-
The feasibility and clinical effects of dendritic cell-based immunotherapy targeting synthesized peptides for recurrent ovarian cancer
-
PID: 25298213
-
Kobayashi M et al. The feasibility and clinical effects of dendritic cell-based immunotherapy targeting synthesized peptides for recurrent ovarian cancer. J Ovarian Res. 2014;7:48.
-
(2014)
J Ovarian Res
, vol.7
, pp. 48
-
-
Kobayashi, M.1
-
21
-
-
84862495613
-
Phase I/II randomized trial of dendritic cell vaccination with or without cyclophosphamide for consolidation therapy of advanced ovarian cancer in first or second remission
-
COI: 1:CAS:528:DC%2BC38XmtlCqsLg%3D, PID: 22021066
-
Chu CS et al. Phase I/II randomized trial of dendritic cell vaccination with or without cyclophosphamide for consolidation therapy of advanced ovarian cancer in first or second remission. Cancer Immunol Immunother. 2012;61(5):629–41.
-
(2012)
Cancer Immunol Immunother
, vol.61
, Issue.5
, pp. 629-641
-
-
Chu, C.S.1
-
22
-
-
0037089223
-
Flt3 ligand as a vaccine adjuvant in association with HER-2/neu peptide-based vaccines in patients with HER-2/neu-overexpressing cancers
-
COI: 1:CAS:528:DC%2BD38XivV2jsr4%3D, PID: 11929774
-
Disis ML et al. Flt3 ligand as a vaccine adjuvant in association with HER-2/neu peptide-based vaccines in patients with HER-2/neu-overexpressing cancers. Blood. 2002;99(8):2845–50.
-
(2002)
Blood
, vol.99
, Issue.8
, pp. 2845-2850
-
-
Disis, M.L.1
-
23
-
-
84859588335
-
Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY-ESO-1 antigen in ovarian cancer and melanoma patients
-
COI: 1:CAS:528:DC%2BC38XmtVOit7w%3D, PID: 22454499
-
Odunsi K et al. Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY-ESO-1 antigen in ovarian cancer and melanoma patients. Proc Natl Acad Sci U S A. 2012;109(15):5797–802.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.15
, pp. 5797-5802
-
-
Odunsi, K.1
-
24
-
-
3543071097
-
A phase I study of Adp53 (INGN 201; ADVEXIN) for patients with platinum- and paclitaxel-resistant epithelial ovarian cancer
-
COI: 1:CAS:528:DC%2BD2cXmsVeqt7s%3D, PID: 15297186
-
Wolf JK et al. A phase I study of Adp53 (INGN 201; ADVEXIN) for patients with platinum- and paclitaxel-resistant epithelial ovarian cancer. Gynecol Oncol. 2004;94(2):442–8.
-
(2004)
Gynecol Oncol
, vol.94
, Issue.2
, pp. 442-448
-
-
Wolf, J.K.1
-
25
-
-
70849115361
-
Regular dose of gemcitabine induces an increase in CD14+ monocytes and CD11c + dendritic cells in patients with advanced pancreatic cancer
-
PID: 19797418
-
Soeda A et al. Regular dose of gemcitabine induces an increase in CD14+ monocytes and CD11c + dendritic cells in patients with advanced pancreatic cancer. Jpn J Clin Oncol. 2009;39(12):797–806.
-
(2009)
Jpn J Clin Oncol
, vol.39
, Issue.12
, pp. 797-806
-
-
Soeda, A.1
-
26
-
-
79959733137
-
Gemcitabine depletes regulatory T-cells in human and mice and enhances triggering of vaccine-specific cytotoxic T-cells
-
COI: 1:CAS:528:DC%2BC3MXnvFansbo%3D, PID: 21710545
-
Rettig L et al. Gemcitabine depletes regulatory T-cells in human and mice and enhances triggering of vaccine-specific cytotoxic T-cells. Int J Cancer. 2011;129(4):832–8.
-
(2011)
Int J Cancer
, vol.129
, Issue.4
, pp. 832-838
-
-
Rettig, L.1
-
27
-
-
12144287745
-
Vaccination of patients with advanced ovarian carcinoma with the anti-idiotype ACA125: immunological response and survival (phase Ib/II)
-
COI: 1:CAS:528:DC%2BD2cXhvFClsLc%3D, PID: 15014007
-
Reinartz S et al. Vaccination of patients with advanced ovarian carcinoma with the anti-idiotype ACA125: immunological response and survival (phase Ib/II). Clin Cancer Res. 2004;10(5):1580–7.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.5
, pp. 1580-1587
-
-
Reinartz, S.1
-
28
-
-
84876529191
-
Abagovomab as maintenance therapy in patients with epithelial ovarian cancer: a phase III trial of the AGO OVAR, COGI, GINECO, and GEICO—the MIMOSA study
-
COI: 1:CAS:528:DC%2BC3sXnvVGgurc%3D, PID: 23478059, In this phase III study, maintenance abagovomab in ovarian cancer patients in first clinical remission, failed to demonstrate a benefit with regard to PFS or OS, despite a robust Ab3 response
-
Sabbatini P et al. Abagovomab as maintenance therapy in patients with epithelial ovarian cancer: a phase III trial of the AGO OVAR, COGI, GINECO, and GEICO—the MIMOSA study. J Clin Oncol. 2013;31(12):1554–61. In this phase III study, maintenance abagovomab in ovarian cancer patients in first clinical remission, failed to demonstrate a benefit with regard to PFS or OS, despite a robust Ab3 response.
-
(2013)
J Clin Oncol
, vol.31
, Issue.12
, pp. 1554-1561
-
-
Sabbatini, P.1
-
29
-
-
14244250598
-
A pilot phase 2 study of oregovomab murine monoclonal antibody to CA125 as an immunotherapeutic agent for recurrent ovarian cancer
-
COI: 1:STN:280:DC%2BD2Mnmt1WrtQ%3D%3D, PID: 16343178
-
Ehlen TG et al. A pilot phase 2 study of oregovomab murine monoclonal antibody to CA125 as an immunotherapeutic agent for recurrent ovarian cancer. Int J Gynecol Cancer. 2005;15(6):1023–34.
-
(2005)
Int J Gynecol Cancer
, vol.15
, Issue.6
, pp. 1023-1034
-
-
Ehlen, T.G.1
-
30
-
-
4444383336
-
Randomized, placebo-controlled study of oregovomab for consolidation of clinical remission in patients with advanced ovarian cancer
-
COI: 1:CAS:528:DC%2BD2cXpsVWku78%3D, PID: 15337799, This randomized phase III trial of maintenance oregovomab in patients with ovarian cancer in complete remission after laparotomy and adjuvant platinum-based chemotherapy failed to demonstrate clinical benefit
-
Berek JS et al. Randomized, placebo-controlled study of oregovomab for consolidation of clinical remission in patients with advanced ovarian cancer. J Clin Oncol. 2004;22(17):3507–16. This randomized phase III trial of maintenance oregovomab in patients with ovarian cancer in complete remission after laparotomy and adjuvant platinum-based chemotherapy failed to demonstrate clinical benefit.
-
(2004)
J Clin Oncol
, vol.22
, Issue.17
, pp. 3507-3516
-
-
Berek, J.S.1
-
31
-
-
77951596808
-
Catumaxomab: clinical development and future directions
-
PID: 20190561
-
Linke R, Klein A, Seimetz D. Catumaxomab: clinical development and future directions. MAbs. 2010;2(2):129–36.
-
(2010)
MAbs
, vol.2
, Issue.2
, pp. 129-136
-
-
Linke, R.1
Klein, A.2
Seimetz, D.3
-
32
-
-
77954676136
-
The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: results of a prospective randomized phase II/III trial
-
COI: 1:CAS:528:DC%2BC3cXhtFSisrbO, PID: 20473913
-
Heiss MM et al. The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: results of a prospective randomized phase II/III trial. Int J Cancer. 2010;127(9):2209–21.
-
(2010)
Int J Cancer
, vol.127
, Issue.9
, pp. 2209-2221
-
-
Heiss, M.M.1
-
33
-
-
84925943630
-
Catumaxomab for the treatment of malignant ascites in patients with chemotherapy-refractory ovarian cancer: a phase II study
-
PID: 25254563
-
Berek JS et al. Catumaxomab for the treatment of malignant ascites in patients with chemotherapy-refractory ovarian cancer: a phase II study. Int J Gynecol Cancer. 2014;24(9):1583–9.
-
(2014)
Int J Gynecol Cancer
, vol.24
, Issue.9
, pp. 1583-1589
-
-
Berek, J.S.1
-
34
-
-
84855401998
-
Immunomonitoring results of a phase II/III study of malignant ascites patients treated with the trifunctional antibody catumaxomab (anti-EpCAM x anti-CD3)
-
PID: 22044753
-
Jager M et al. Immunomonitoring results of a phase II/III study of malignant ascites patients treated with the trifunctional antibody catumaxomab (anti-EpCAM x anti-CD3). Cancer Res. 2012;72(1):24–32.
-
(2012)
Cancer Res
, vol.72
, Issue.1
, pp. 24-32
-
-
Jager, M.1
-
35
-
-
33749349945
-
Preclinical evaluation of an anti-alpha5beta1 integrin antibody as a novel anti-angiogenic agent
-
COI: 1:CAS:528:DC%2BD28XhtV2ru77K, PID: 17024968
-
Ramakrishnan V et al. Preclinical evaluation of an anti-alpha5beta1 integrin antibody as a novel anti-angiogenic agent. J Exp Ther Oncol. 2006;5(4):273–86.
-
(2006)
J Exp Ther Oncol
, vol.5
, Issue.4
, pp. 273-286
-
-
Ramakrishnan, V.1
-
36
-
-
78649356052
-
Phase II study comparing volociximab (an antiangiogenic antibody) and pegylated liposomal doxorubicin (PLD) with PLD alone in recurrent ovarian or primary peritoneal cancer
-
Vergote IB et al. Phase II study comparing volociximab (an antiangiogenic antibody) and pegylated liposomal doxorubicin (PLD) with PLD alone in recurrent ovarian or primary peritoneal cancer. J Clin Oncol. 2009;27(15):Abstract 5560.
-
(2009)
J Clin Oncol
, vol.27
, Issue.15
, pp. 5560
-
-
Vergote, I.B.1
-
37
-
-
84863483737
-
Farletuzumab, an anti-folate receptor alpha antibody, does not block binding of folate or anti-folates to receptor nor does it alter the potency of anti-folates in vitro
-
COI: 1:CAS:528:DC%2BC38XpsFajtL4%3D, PID: 22644798
-
Kamen BA, Smith AK. Farletuzumab, an anti-folate receptor alpha antibody, does not block binding of folate or anti-folates to receptor nor does it alter the potency of anti-folates in vitro. Cancer Chemother Pharmacol. 2012;70(1):113–20.
-
(2012)
Cancer Chemother Pharmacol
, vol.70
, Issue.1
, pp. 113-120
-
-
Kamen, B.A.1
Smith, A.K.2
-
38
-
-
78649926327
-
Efficacy and safety of farletuzumab, a humanized monoclonal antibody to folate receptor alpha, in platinum-sensitive relapsed ovarian cancer subjects: final data from a multicenter phase II study
-
In this phase II study the addition of farletuzumab to combination chemotherapy increased the duration of second remission compared to first remission
-
White AJ et al. Efficacy and safety of farletuzumab, a humanized monoclonal antibody to folate receptor alpha, in platinum-sensitive relapsed ovarian cancer subjects: final data from a multicenter phase II study. J Clin Oncol. 2010;28(15):Abstract 5001. In this phase II study the addition of farletuzumab to combination chemotherapy increased the duration of second remission compared to first remission.
-
(2010)
J Clin Oncol
, vol.28
, Issue.15
, pp. 5001
-
-
White, A.J.1
-
39
-
-
84904278154
-
Phase 3 double-blind, placebo-controlled study of weekly farletuzumab with carboplatin/taxane in subjects with platinum sensitive ovarian cancer in first relapse
-
In this randomized phase III study, farletuzumab in combination with carboplatin/taxane did not improve PFS compared to chemotherapy alone
-
Vergote I, Armstrong D. Phase 3 double-blind, placebo-controlled study of weekly farletuzumab with carboplatin/taxane in subjects with platinum sensitive ovarian cancer in first relapse. Int J Gynecol Cancer. 2013;23 Suppl 8:11. In this randomized phase III study, farletuzumab in combination with carboplatin/taxane did not improve PFS compared to chemotherapy alone.
-
(2013)
Int J Gynecol Cancer
, vol.23
, pp. 11
-
-
Vergote, I.1
Armstrong, D.2
-
40
-
-
84943764538
-
Targeting the folate receptor: diagnostic and therapeutic approaches to personalize cancer treatments
-
COI: 1:STN:280:DC%2BC2Mbis1ekuw%3D%3D, PID: 26063635
-
Ledermann JA, Canevari S, Thigpen T. Targeting the folate receptor: diagnostic and therapeutic approaches to personalize cancer treatments. Ann Oncol. 2015;26(10):2034–43.
-
(2015)
Ann Oncol
, vol.26
, Issue.10
, pp. 2034-2043
-
-
Ledermann, J.A.1
Canevari, S.2
Thigpen, T.3
-
41
-
-
84925456254
-
Role of the folate receptor in ovarian cancer treatment: evidence, mechanism, and clinical implications
-
COI: 1:CAS:528:DC%2BC2MXhtVKrs78%3D, PID: 25564455
-
Vergote IB, Marth C, Coleman RL. Role of the folate receptor in ovarian cancer treatment: evidence, mechanism, and clinical implications. Cancer Metastasis Rev. 2015;34(1):41–52.
-
(2015)
Cancer Metastasis Rev
, vol.34
, Issue.1
, pp. 41-52
-
-
Vergote, I.B.1
Marth, C.2
Coleman, R.L.3
-
42
-
-
84937681320
-
Immunotherapy of ovarian cancer: the role of checkpoint inhibitors
-
PID: 26236750
-
De Felice F et al. Immunotherapy of ovarian cancer: the role of checkpoint inhibitors. J Immunol Res. 2015;2015:191832.
-
(2015)
J Immunol Res
, vol.2015
, pp. 191832
-
-
De Felice, F.1
-
43
-
-
84905753981
-
Efficacy and safety of anti-PD-1 antibody (Nivolumab: BMS-936558, ONO-4538) in patients with platinum-resistant ovarian cancer
-
This abstracts reports efficacy data of nivolumab in patients with platinum-resistant ovarian cance
-
Hamanishi J et al. Efficacy and safety of anti-PD-1 antibody (Nivolumab: BMS-936558, ONO-4538) in patients with platinum-resistant ovarian cancer. J Clin Oncol. 2014;32(15):5511. This abstracts reports efficacy data of nivolumab in patients with platinum-resistant ovarian cance.
-
(2014)
J Clin Oncol
, vol.32
, Issue.15
, pp. 5511
-
-
Hamanishi, J.1
-
44
-
-
85026938366
-
-
Hamanishi J et al. Durable tumor remission in patients with platinum-resistant ovarian cancer receiving nivolumab. J Clin Oncol. 2015;33(15). This abstract reports durable remission to nivolumab in ovarian cancer patients.
-
Hamanishi J et al. Durable tumor remission in patients with platinum-resistant ovarian cancer receiving nivolumab. J Clin Oncol. 2015;33(15). This abstract reports durable remission to nivolumab in ovarian cancer patients.
-
-
-
-
45
-
-
84937721776
-
Antitumor activity and safety of pembrolizumab in patients (pts) with PD-L1 positive advanced ovarian cancer: interim results from a phase Ib study
-
This abstract presents the efficacy and safety of pembrolizumab in ovarian cancer patients of a large chort phase Ib study conducted in patients with advanced solid tumors
-
Varga A et al. Antitumor activity and safety of pembrolizumab in patients (pts) with PD-L1 positive advanced ovarian cancer: interim results from a phase Ib study. J Clin Oncol. 2015;33(15):Abstract 5510. This abstract presents the efficacy and safety of pembrolizumab in ovarian cancer patients of a large chort phase Ib study conducted in patients with advanced solid tumors.
-
(2015)
J Clin Oncol
, vol.33
, Issue.15
, pp. 5510
-
-
Varga, A.1
-
46
-
-
84937690774
-
Avelumab (MSB0010718C), an anti-PD-L1 antibody, in patients with previously treated, recurrent or refractory ovarian cancer: a phase Ib, open-label expansion trial
-
This study included a cohort of seventy-five patients with refractory or recurrent ovarian cancer treated with avelumab.
-
Disis ML et al. Avelumab (MSB0010718C), an anti-PD-L1 antibody, in patients with previously treated, recurrent or refractory ovarian cancer: a phase Ib, open-label expansion trial. J Clin Oncol. 2015;33(15):Abstract 5509. This study included a cohort of seventy-five patients with refractory or recurrent ovarian cancer treated with avelumab.
-
(2015)
J Clin Oncol
, vol.33
, Issue.15
, pp. 5509
-
-
Disis, M.L.1
-
47
-
-
84925545111
-
Clinical blockade of PD1 and LAG3-potential mechanisms of action
-
COI: 1:CAS:528:DC%2BC2cXitFKltb7I, PID: 25534622
-
Nguyen LT, Ohashi PS. Clinical blockade of PD1 and LAG3-potential mechanisms of action. Nat Rev Immunol. 2015;15(1):45–56.
-
(2015)
Nat Rev Immunol
, vol.15
, Issue.1
, pp. 45-56
-
-
Nguyen, L.T.1
Ohashi, P.S.2
-
48
-
-
84942899415
-
The evolution of T-cell therapies for solid malignancies
-
COI: 1:CAS:528:DC%2BC2MXht1yqtrjF, PID: 26240290
-
Fousek K, Ahmed N. The evolution of T-cell therapies for solid malignancies. Clin Cancer Res. 2015;21(15):3384–92.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.15
, pp. 3384-3392
-
-
Fousek, K.1
Ahmed, N.2
-
49
-
-
0024166189
-
Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report
-
COI: 1:STN:280:DyaL1M%2FntVKmsw%3D%3D, PID: 3264384
-
Rosenberg SA et al. Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report. N Engl J Med. 1988;319(25):1676–80.
-
(1988)
N Engl J Med
, vol.319
, Issue.25
, pp. 1676-1680
-
-
Rosenberg, S.A.1
-
50
-
-
0025859335
-
Use of adoptive transfer of tumor-infiltrating lymphocytes alone or in combination with cisplatin-containing chemotherapy in patients with epithelial ovarian cancer
-
COI: 1:STN:280:DyaK3M7mvVWksQ%3D%3D, PID: 2004379
-
Aoki Y et al. Use of adoptive transfer of tumor-infiltrating lymphocytes alone or in combination with cisplatin-containing chemotherapy in patients with epithelial ovarian cancer. Cancer Res. 1991;51(7):1934–9.
-
(1991)
Cancer Res
, vol.51
, Issue.7
, pp. 1934-1939
-
-
Aoki, Y.1
-
51
-
-
0029049890
-
Prolonged disease-free period in patients with advanced epithelial ovarian cancer after adoptive transfer of tumor-infiltrating lymphocytes
-
COI: 1:STN:280:DyaK1M%2FjsVynsw%3D%3D, PID: 9816009
-
Fujita K et al. Prolonged disease-free period in patients with advanced epithelial ovarian cancer after adoptive transfer of tumor-infiltrating lymphocytes. Clin Cancer Res. 1995;1(5):501–7.
-
(1995)
Clin Cancer Res
, vol.1
, Issue.5
, pp. 501-507
-
-
Fujita, K.1
-
52
-
-
44249118831
-
Recognition of naturally processed and ovarian cancer reactive CD8+ T cell epitopes within a promiscuous HLA class II T-helper region of NY-ESO-1
-
COI: 1:CAS:528:DC%2BD1cXmt1OisLs%3D, PID: 18253733
-
Matsuzaki J et al. Recognition of naturally processed and ovarian cancer reactive CD8+ T cell epitopes within a promiscuous HLA class II T-helper region of NY-ESO-1. Cancer Immunol Immunother. 2008;57(8):1185–95.
-
(2008)
Cancer Immunol Immunother
, vol.57
, Issue.8
, pp. 1185-1195
-
-
Matsuzaki, J.1
-
53
-
-
84928912377
-
A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: long-term follow-up and correlates with response
-
COI: 1:CAS:528:DC%2BC2MXjsF2itrc%3D, PID: 25538264
-
Robbins PF et al. A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: long-term follow-up and correlates with response. Clin Cancer Res. 2015;21(5):1019–27.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.5
, pp. 1019-1027
-
-
Robbins, P.F.1
-
54
-
-
85026941343
-
-
Merchant MS et al. Genetically engineered NY-ESO-1 specific T cells in HLA-A201 + patients with advanced cancers. J Clin Oncol. 2015;33(15).
-
Merchant MS et al. Genetically engineered NY-ESO-1 specific T cells in HLA-A201 + patients with advanced cancers. J Clin Oncol. 2015;33(15).
-
-
-
-
55
-
-
84877669593
-
The basic principles of chimeric antigen receptor design
-
COI: 1:CAS:528:DC%2BC3sXlvVCit7c%3D, PID: 23550147
-
Sadelain M, Brentjens R, Riviere I. The basic principles of chimeric antigen receptor design. Cancer Discov. 2013;3(4):388–98.
-
(2013)
Cancer Discov
, vol.3
, Issue.4
, pp. 388-398
-
-
Sadelain, M.1
Brentjens, R.2
Riviere, I.3
-
56
-
-
84879838880
-
Collaboration of chimeric antigen receptor (CAR)-expressing T cells and host T cells for optimal elimination of established ovarian tumors
-
PID: 23734311
-
Spear P, Barber A, Sentman CL. Collaboration of chimeric antigen receptor (CAR)-expressing T cells and host T cells for optimal elimination of established ovarian tumors. Oncoimmunology. 2013;2(4):e23564.
-
(2013)
Oncoimmunology
, vol.2
, Issue.4
, pp. e23564
-
-
Spear, P.1
Barber, A.2
Sentman, C.L.3
-
57
-
-
84864518399
-
A phase I clinical trial of adoptive transfer of folate receptor-alpha redirected autologous T cells for recurrent ovarian cancer
-
COI: 1:CAS:528:DC%2BC38XhvVShsr%2FI, PID: 22863016
-
Kandalaft LE, Powell Jr DJ, Coukos G. A phase I clinical trial of adoptive transfer of folate receptor-alpha redirected autologous T cells for recurrent ovarian cancer. J Transl Med. 2012;10:157.
-
(2012)
J Transl Med
, vol.10
, pp. 157
-
-
Kandalaft, L.E.1
Powell, D.J.2
Coukos, G.3
|