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Volumn 21, Issue 15, 2015, Pages 3384-3392

The evolution of T-cell therapies for solid malignancies

Author keywords

[No Author keywords available]

Indexed keywords

ADOPTIVE TRANSFER; ANTINEOPLASTIC ACTIVITY; CANCER CHEMOTHERAPY; CANCER IMMUNOTHERAPY; CELL KILLING; HUMAN; NONHUMAN; PRIMARY TUMOR; PRIORITY JOURNAL; REVIEW; SIDE EFFECT; SOLID TUMOR; T LYMPHOCYTE; TREATMENT RESPONSE; TUMOR CELL; TUMOR MICROENVIRONMENT; TUMOR RECURRENCE; TUMOR RESISTANCE; ADOPTIVE IMMUNOTHERAPY; DRUG RESISTANCE; GENETICS; IMMUNOLOGY; NEOPLASMS; TRANSPLANTATION;

EID: 84942899415     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-14-2675     Document Type: Review
Times cited : (73)

References (61)
  • 2
    • 34249868241 scopus 로고    scopus 로고
    • Adoptive T cell therapy for cancer in the clinic
    • June CH Adoptive T cell therapy for cancer in the clinic. J Clin Invest 2007; 117: 1466-76.
    • (2007) J Clin Invest , vol.117 , pp. 1466-1476
    • June, C.H.1
  • 3
    • 76949100884 scopus 로고    scopus 로고
    • Accelerated production of antigen-specific T cells for preclinical and clinical applications using gas-permeable rapid expansion cultureware (G-Rex)
    • Vera JF, Brenner LJ, Gerdemann U, Ngo MC, Sili U, Liu H, et al. Accelerated production of antigen-specific T cells for preclinical and clinical applications using gas-permeable rapid expansion cultureware (G-Rex). J Immunother 2010; 33: 305-15.
    • (2010) J Immunother , vol.33 , pp. 305-315
    • Vera, J.F.1    Brenner, L.J.2    Gerdemann, U.3    Ngo, M.C.4    Sili, U.5    Liu, H.6
  • 4
    • 0024166189 scopus 로고
    • Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma: A preliminary report
    • Rosenberg SA, Packard BS, Aebersold PM, Solomon D, Topalian SL, Toy ST, et al. Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma: a preliminary report. N Engl J Med 1988; 319: 1676-80.
    • (1988) N Engl J Med , vol.319 , pp. 1676-1680
    • Rosenberg, S.A.1    Packard, B.S.2    Aebersold, P.M.3    Solomon, D.4    Topalian, S.L.5    Toy, S.T.6
  • 5
    • 84890239280 scopus 로고    scopus 로고
    • Adoptive immunotherapy for cancer
    • Ruella M, Kalos M. Adoptive immunotherapy for cancer. Immunol Rev 2014; 257: 14-38.
    • (2014) Immunol Rev , vol.257 , pp. 14-38
    • Ruella, M.1    Kalos, M.2
  • 6
    • 55949125601 scopus 로고    scopus 로고
    • Adoptive cell therapy for patients with metastatic melanoma: Evaluation of intensive myeloablative chemoradiation preparative regimens
    • Dudley ME, Yang JC, Sherry R, Hughes MS, Royal R, Kammula U, et al. Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens. J Clin Oncol 2008; 26: 5233-9.
    • (2008) J Clin Oncol , vol.26 , pp. 5233-5239
    • Dudley, M.E.1    Yang, J.C.2    Sherry, R.3    Hughes, M.S.4    Royal, R.5    Kammula, U.6
  • 7
    • 79960299888 scopus 로고    scopus 로고
    • Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy
    • Rosenberg SA, Yang JC, Sherry RM, Kammula US, Hughes MS, Phan GQ, et al. Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy. Clin Cancer Res 2011; 17: 4550-7.
    • (2011) Clin Cancer Res , vol.17 , pp. 4550-4557
    • Rosenberg, S.A.1    Yang, J.C.2    Sherry, R.M.3    Kammula, U.S.4    Hughes, M.S.5    Phan, G.Q.6
  • 8
    • 78349255049 scopus 로고    scopus 로고
    • Transduction of tumor-specific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responses
    • Peng W, Ye Y, Rabinovich BA, Liu C, Lou Y, Zhang M, et al. Transduction of tumor-specific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responses. Clin Cancer Res 2010; 16: 5458-68.
    • (2010) Clin Cancer Res , vol.16 , pp. 5458-5468
    • Peng, W.1    Ye, Y.2    Rabinovich, B.A.3    Liu, C.4    Lou, Y.5    Zhang, M.6
  • 9
    • 35549008976 scopus 로고    scopus 로고
    • Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer
    • Bollard CM, Gottschalk S, Leen AM, Weiss H, Straathof KC, Carrum G, et al. Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer. Blood 2007; 110: 2838-45.
    • (2007) Blood , vol.110 , pp. 2838-2845
    • Bollard, C.M.1    Gottschalk, S.2    Leen, A.M.3    Weiss, H.4    Straathof, K.C.5    Carrum, G.6
  • 10
    • 0028816546 scopus 로고
    • Use of genemodified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation
    • Rooney CM, Smith CA, Ng CY, Loftin S, Li C, Krance RA, et al. Use of genemodified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation. Lancet 1995; 345: 9-13.
    • (1995) Lancet , vol.345 , pp. 9-13
    • Rooney, C.M.1    Smith, C.A.2    Ng, C.Y.3    Loftin, S.4    Li, C.5    Krance, R.A.6
  • 11
    • 20144365643 scopus 로고    scopus 로고
    • Treatment of nasopharyngeal carcinoma with Epstein-Barr virus-specific T lymphocytes
    • Straathof KC, Bollard CM, Popat U, Huls MH, Lopez T, Morriss MC, et al. Treatment of nasopharyngeal carcinoma with Epstein-Barr virus-specific T lymphocytes. Blood 2005; 105: 1898-904.
    • (2005) Blood , vol.105 , pp. 1898-1904
    • Straathof, K.C.1    Bollard, C.M.2    Popat, U.3    Huls, M.H.4    Lopez, T.5    Morriss, M.C.6
  • 12
    • 84856845120 scopus 로고    scopus 로고
    • Generation of polyclonal CMV-specific T cells for the adoptive immunotherapy of glioblastoma
    • Ghazi A, Ashoori A, Hanley PJ, Brawley VS, Shaffer DR, Kew Y, et al. Generation of polyclonal CMV-specific T cells for the adoptive immunotherapy of glioblastoma. J Immunother 2012; 35: 159-68.
    • (2012) J Immunother , vol.35 , pp. 159-168
    • Ghazi, A.1    Ashoori, A.2    Hanley, P.J.3    Brawley, V.S.4    Shaffer, D.R.5    Kew, Y.6
  • 13
    • 84903621256 scopus 로고    scopus 로고
    • Autologous T-cell therapy forcytomegalovirus as a consolidative treatment for recurrent glioblastoma
    • Schuessler A, Smith C, Beagley L, Boyle GM, Rehan S, Matthews K, et al. Autologous T-cell therapy forcytomegalovirus as a consolidative treatment for recurrent glioblastoma. Cancer Res 2014; 74: 3466-76.
    • (2014) Cancer Res , vol.74 , pp. 3466-3476
    • Schuessler, A.1    Smith, C.2    Beagley, L.3    Boyle, G.M.4    Rehan, S.5    Matthews, K.6
  • 14
    • 0037829421 scopus 로고    scopus 로고
    • Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients
    • Dudley ME, Wunderlich JR, Shelton TE, Even J, Rosenberg SA. Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients. J Immunother 2003; 26: 332-42.
    • (2003) J Immunother , vol.26 , pp. 332-342
    • Dudley, M.E.1    Wunderlich, J.R.2    Shelton, T.E.3    Even, J.4    Rosenberg, S.A.5
  • 18
    • 79952304769 scopus 로고    scopus 로고
    • Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NYESO-1
    • Robbins PF, Morgan RA, Feldman SA, Yang JC, Sherry RM, Dudley ME, et al. Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NYESO-1. J Clin Oncol 2011; 29: 917-24.
    • (2011) J Clin Oncol , vol.29 , pp. 917-924
    • Robbins, P.F.1    Morgan, R.A.2    Feldman, S.A.3    Yang, J.C.4    Sherry, R.M.5    Dudley, M.E.6
  • 19
    • 33845985925 scopus 로고    scopus 로고
    • Efficiency of T-cell receptor expression in dual-specific T cells is controlled by the intrinsic qualities of the TCR chains within the TCR-CD3 complex
    • Heemskerk MH, Hagedoorn RS, van der Hoorn MA, van der Veken LT, Hoogeboom M, Kester MG, et al. Efficiency of T-cell receptor expression in dual-specific T cells is controlled by the intrinsic qualities of the TCR chains within the TCR-CD3 complex. Blood 2007; 109: 235-43.
    • (2007) Blood , vol.109 , pp. 235-243
    • Heemskerk, M.H.1    Hagedoorn, R.S.2    Van Der Hoorn, M.A.3    Van Der Veken, L.T.4    Hoogeboom, M.5    Kester, M.G.6
  • 21
    • 33947217494 scopus 로고    scopus 로고
    • Facilitating matched pairing and expression of TCR chains introduced into human T cells
    • Kuball J, Dossett ML, Wolfl M, Ho WY, Voss RH, Fowler C, et al. Facilitating matched pairing and expression of TCR chains introduced into human T cells. Blood 2007; 109: 2331-8.
    • (2007) Blood , vol.109 , pp. 2331-2338
    • Kuball, J.1    Dossett, M.L.2    Wolfl, M.3    Ho, W.Y.4    Voss, R.H.5    Fowler, C.6
  • 22
    • 47249100641 scopus 로고    scopus 로고
    • Human TCR that incorporate CD3z induce highly preferred pairing between TCRα and β chains following gene transfer
    • Sebestyen Z, Schooten E, Sals T, Zaldivar I, San Jose E, Alarcon B, et al. Human TCR that incorporate CD3z induce highly preferred pairing between TCRα and β chains following gene transfer. J Immunol 2008; 180: 7736-46.
    • (2008) J Immunol , vol.180 , pp. 7736-7746
    • Sebestyen, Z.1    Schooten, E.2    Sals, T.3    Zaldivar, I.4    San Jose, E.5    Alarcon, B.6
  • 24
    • 84891076242 scopus 로고    scopus 로고
    • Immunotherapy with TCR-redirected Tcells: Comparison of TCR-transduced and TCR-engineered hematopoietic stem cell-derived T cells
    • Starck L, Popp K, Pircher H, Uckert W. Immunotherapy with TCR-redirected Tcells: comparison of TCR-transduced and TCR-engineered hematopoietic stem cell-derived T cells. J Immunol 2014; 192: 206-13.
    • (2014) J Immunol , vol.192 , pp. 206-213
    • Starck, L.1    Popp, K.2    Pircher, H.3    Uckert, W.4
  • 25
    • 84860681545 scopus 로고    scopus 로고
    • Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer
    • Provasi E, Genovese P, Lombardo A, Magnani Z, Liu PQ, Reik A, et al. Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer. Nat Med 2012; 18: 807-15.
    • (2012) Nat Med , vol.18 , pp. 807-815
    • Provasi, E.1    Genovese, P.2    Lombardo, A.3    Magnani, Z.4    Liu, P.Q.5    Reik, A.6
  • 26
    • 0027471898 scopus 로고
    • Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors
    • Eshhar Z, Waks T, Gross G, Schindler DG. Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors. Proc Natl Acad Sci U S A 1993; 90: 720-4.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 720-724
    • Eshhar, Z.1    Waks, T.2    Gross, G.3    Schindler, D.G.4
  • 27
    • 84890181067 scopus 로고    scopus 로고
    • Design and development of therapies using chimeric antigen receptor-expressing T cells
    • Dotti G, Gottschalk S, Savoldo B, Brenner MK. Design and development of therapies using chimeric antigen receptor-expressing T cells. Immunol Rev 2014; 257: 107-26.
    • (2014) Immunol Rev , vol.257 , pp. 107-126
    • Dotti, G.1    Gottschalk, S.2    Savoldo, B.3    Brenner, M.K.4
  • 28
    • 84899631361 scopus 로고    scopus 로고
    • Antibody-modified T cells: CARs take the front seat for hematologic malignancies
    • Maus MV, Grupp SA, Porter DL, June CH. Antibody-modified T cells: CARs take the front seat for hematologic malignancies. Blood 2014; 123: 2625-35.
    • (2014) Blood , vol.123 , pp. 2625-2635
    • Maus, M.V.1    Grupp, S.A.2    Porter, D.L.3    June, C.H.4
  • 29
    • 79955517235 scopus 로고    scopus 로고
    • CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients
    • Savoldo B, Ramos CA, Liu E, Mims MP, Keating MJ, Carrum G, et al. CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients. J Clin Invest 2011; 121: 1822-6.
    • (2011) J Clin Invest , vol.121 , pp. 1822-1826
    • Savoldo, B.1    Ramos, C.A.2    Liu, E.3    Mims, M.P.4    Keating, M.J.5    Carrum, G.6
  • 31
    • 84920691639 scopus 로고    scopus 로고
    • Engager T cells: A new class of antigen-specific T cells that redirect bystander T cells
    • Iwahori K, Kakarla S, Velasquez MP, Yu F, Yi Z, Gerken C, et al. Engager T cells: a new class of antigen-specific T cells that redirect bystander T cells. Mol Ther 2015; 23: 171-8.
    • (2015) Mol Ther , vol.23 , pp. 171-178
    • Iwahori, K.1    Kakarla, S.2    Velasquez, M.P.3    Yu, F.4    Yi, Z.5    Gerken, C.6
  • 32
    • 84887471195 scopus 로고    scopus 로고
    • Combinational targeting offsets antigen escape and enhances effector functions of adoptively transferred T cells in glioblastoma
    • Hegde M, Corder A, Chow KK, Mukherjee M, Ashoori A, Kew Y, et al. Combinational targeting offsets antigen escape and enhances effector functions of adoptively transferred T cells in glioblastoma. Mol Ther 2013; 21: 2087-101.
    • (2013) Mol Ther , vol.21 , pp. 2087-2101
    • Hegde, M.1    Corder, A.2    Chow, K.K.3    Mukherjee, M.4    Ashoori, A.5    Kew, Y.6
  • 34
    • 84881312673 scopus 로고    scopus 로고
    • Antitumor effects of chimeric receptor engineered human T cells directed to tumor stroma
    • Kakarla S, Chow KK, Mata M, Shaffer DR, Song XT, Wu MF, et al. Antitumor effects of chimeric receptor engineered human T cells directed to tumor stroma. Mol Ther 2013; 21: 1611-20.
    • (2013) Mol Ther , vol.21 , pp. 1611-1620
    • Kakarla, S.1    Chow, K.K.2    Mata, M.3    Shaffer, D.R.4    Song, X.T.5    Wu, M.F.6
  • 35
    • 55249117972 scopus 로고    scopus 로고
    • Antitumor activity of EBV-specific T lymphocytes transduced with a dominant negative TGF-b receptor
    • Foster AE, Dotti G, Lu A, Khalil M, Brenner MK, Heslop HE, et al. Antitumor activity of EBV-specific T lymphocytes transduced with a dominant negative TGF-b receptor. J Immunother 2008; 31: 500-5.
    • (2008) J Immunother , vol.31 , pp. 500-505
    • Foster, A.E.1    Dotti, G.2    Lu, A.3    Khalil, M.4    Brenner, M.K.5    Heslop, H.E.6
  • 37
    • 19944426039 scopus 로고    scopus 로고
    • New frontiers in translational research in neuro-oncology and the blood-brain barrier: Report of the tenth annual Blood-Brain Barrier Disruption Consortium Meeting
    • Doolittle ND, Abrey LE, Bleyer WA, Brem S, Davis TP, Dore-Duffy P, et al. New frontiers in translational research in neuro-oncology and the blood-brain barrier: report of the tenth annual Blood-Brain Barrier Disruption Consortium Meeting. Clin Cancer Res 2005; 11: 421-8.
    • (2005) Clin Cancer Res , vol.11 , pp. 421-428
    • Doolittle, N.D.1    Abrey, L.E.2    Bleyer, W.A.3    Brem, S.4    Davis, T.P.5    Dore-Duffy, P.6
  • 38
    • 84927574518 scopus 로고    scopus 로고
    • Immune modulation for cancer therapy
    • Naidoo J, Page DB, Wolchok JD. Immune modulation for cancer therapy. Br J Cancer 2014; 111: 2214-9.
    • (2014) Br J Cancer , vol.111 , pp. 2214-2219
    • Naidoo, J.1    Page, D.B.2    Wolchok, J.D.3
  • 39
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012; 12: 252-64.
    • (2012) Nat Rev Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 43
    • 70149114880 scopus 로고    scopus 로고
    • Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
    • Johnson LA, Morgan RA, Dudley ME, Cassard L, Yang JC, Hughes MS, et al. Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen. Blood 2009; 114: 535-46.
    • (2009) Blood , vol.114 , pp. 535-546
    • Johnson, L.A.1    Morgan, R.A.2    Dudley, M.E.3    Cassard, L.4    Yang, J.C.5    Hughes, M.S.6
  • 44
    • 84880730689 scopus 로고    scopus 로고
    • Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma
    • Linette GP, Stadtmauer EA, Maus MV, Rapoport AP, Levine BL, Emery L, et al. Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma. Blood 2013; 122: 863-71.
    • (2013) Blood , vol.122 , pp. 863-871
    • Linette, G.P.1    Stadtmauer, E.A.2    Maus, M.V.3    Rapoport, A.P.4    Levine, B.L.5    Emery, L.6
  • 45
    • 77950475517 scopus 로고    scopus 로고
    • Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
    • Morgan RA, Yang JC, Kitano M, Dudley ME, Laurencot CM, Rosenberg SA. Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol Ther 2010; 18: 843-51.
    • (2010) Mol Ther , vol.18 , pp. 843-851
    • Morgan, R.A.1    Yang, J.C.2    Kitano, M.3    Dudley, M.E.4    Laurencot, C.M.5    Rosenberg, S.A.6
  • 47
    • 65349157330 scopus 로고    scopus 로고
    • Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): A non-randomised phase I-II study
    • Ciceri F, Bonini C, Stanghellini MT, Bondanza A, Traversari C, Salomoni M, et al. Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study. Lancet Oncol 2009; 10: 489-500.
    • (2009) Lancet Oncol , vol.10 , pp. 489-500
    • Ciceri, F.1    Bonini, C.2    Stanghellini, M.T.3    Bondanza, A.4    Traversari, C.5    Salomoni, M.6
  • 49
    • 84872196489 scopus 로고    scopus 로고
    • Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells
    • Kloss CC, Condomines M, Cartellieri M, Bachmann M, Sadelain M. Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells. Nat Biotechnol 2013; 31: 71-5.
    • (2013) Nat Biotechnol , vol.31 , pp. 71-75
    • Kloss, C.C.1    Condomines, M.2    Cartellieri, M.3    Bachmann, M.4    Sadelain, M.5
  • 50
    • 84904097189 scopus 로고    scopus 로고
    • Current concepts in the diagnosis and management of cytokine release syndrome
    • Lee DW, Gardner R, Porter DL, Louis CU, Ahmed N, Jensen M, et al. Current concepts in the diagnosis and management of cytokine release syndrome. Blood 2014; 124: 188-95.
    • (2014) Blood , vol.124 , pp. 188-195
    • Lee, D.W.1    Gardner, R.2    Porter, D.L.3    Louis, C.U.4    Ahmed, N.5    Jensen, M.6
  • 51
    • 0029688251 scopus 로고    scopus 로고
    • Adoptive cellular immunotherapy of cancer in mice using allogeneic T-cells
    • Bartels CJ, Rosenberg SA, Yang JC. Adoptive cellular immunotherapy of cancer in mice using allogeneic T-cells. Ann Surg Oncol 1996; 3: 67-73.
    • (1996) Ann Surg Oncol , vol.3 , pp. 67-73
    • Bartels, C.J.1    Rosenberg, S.A.2    Yang, J.C.3
  • 52
    • 34250844475 scopus 로고    scopus 로고
    • Regression of experimental medulloblastoma following transfer of HER2specific T cells
    • Ahmed N, Ratnayake M, Savoldo B, Perlaky L, Dotti G, Wels WS, et al. Regression of experimental medulloblastoma following transfer of HER2specific T cells. Cancer Res 2007; 67: 5957-64.
    • (2007) Cancer Res , vol.67 , pp. 5957-5964
    • Ahmed, N.1    Ratnayake, M.2    Savoldo, B.3    Perlaky, L.4    Dotti, G.5    Wels, W.S.6
  • 53
    • 74549196076 scopus 로고    scopus 로고
    • HER2specific T cells target primary glioblastoma stem cells and induce regression of autologous experimental tumors
    • Ahmed N, Salsman VS, Kew Y, Shaffer D, Powell S, Zhang YJ, et al. HER2specific T cells target primary glioblastoma stem cells and induce regression of autologous experimental tumors. Clin Cancer Res 2010; 16: 474-85.
    • (2010) Clin Cancer Res , vol.16 , pp. 474-485
    • Ahmed, N.1    Salsman, V.S.2    Kew, Y.3    Shaffer, D.4    Powell, S.5    Zhang, Y.J.6
  • 54
    • 70349852616 scopus 로고    scopus 로고
    • Immunotherapy for osteosarcoma: Genetic modification of T cells overcomes low levels of tumor antigen expression
    • Ahmed N, Salsman VS, Yvon E, Louis CU, Perlaky L, Wels WS, et al. Immunotherapy for osteosarcoma: genetic modification of T cells overcomes low levels of tumor antigen expression. Mol Ther 2009; 17: 1779-87.
    • (2009) Mol Ther , vol.17 , pp. 1779-1787
    • Ahmed, N.1    Salsman, V.S.2    Yvon, E.3    Louis, C.U.4    Perlaky, L.5    Wels, W.S.6
  • 55
    • 84859820456 scopus 로고    scopus 로고
    • Stem-like tumor-initiating cells isolated from IL13Ra2 expressing gliomas are targeted and killed by IL13-zetakine-redirected T Cells
    • Brown CE, Starr R, Aguilar B, Shami AF, Martinez C, D'Apuzzo M, et al. Stem-like tumor-initiating cells isolated from IL13Ra2 expressing gliomas are targeted and killed by IL13-zetakine-redirected T Cells. Clin Cancer Res 2012; 18: 2199-209.
    • (2012) Clin Cancer Res , vol.18 , pp. 2199-2209
    • Brown, C.E.1    Starr, R.2    Aguilar, B.3    Shami, A.F.4    Martinez, C.5    D'Apuzzo, M.6
  • 57
    • 84911213409 scopus 로고    scopus 로고
    • Genetic modification of T cells with a novel bispecific chimeric antigen receptor to enhance the control of high-grade glioma (HGG)
    • 10027
    • Hegde M, Wakefield A, Brawley VS, Grada Z, Byrd TT, Chow KK, et al. Genetic modification of T cells with a novel bispecific chimeric antigen receptor to enhance the control of high-grade glioma (HGG). J Clin Oncol 32: 15s, 2014. (suppl; abstr 10027).
    • (2014) J Clin Oncol , vol.32 , pp. 15s
    • Hegde, M.1    Wakefield, A.2    Brawley, V.S.3    Grada, Z.4    Byrd, T.T.5    Chow, K.K.6
  • 58
    • 79952187823 scopus 로고    scopus 로고
    • T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis
    • Parkhurst MR, Yang JC, Langan RC, Dudley ME, Nathan DA, Feldman SA, et al. T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis. Mol Ther 2011; 19: 620-6.
    • (2011) Mol Ther , vol.19 , pp. 620-626
    • Parkhurst, M.R.1    Yang, J.C.2    Langan, R.C.3    Dudley, M.E.4    Nathan, D.A.5    Feldman, S.A.6
  • 59
    • 84933513655 scopus 로고    scopus 로고
    • Human epidermal growth factor receptor 2 (HER2) -specific chimeric antigen receptor-modified T cells for the immunotherapy of HER2-positive sarcoma
    • Ahmed N, Brawley VS, Hegde M, Robertson C, Ghazi A, Gerken C, et al. Human epidermal growth factor receptor 2 (HER2) -specific chimeric antigen receptor-modified T cells for the immunotherapy of HER2-positive sarcoma. J Clin Oncol 2015; 33: 1688-96.
    • (2015) J Clin Oncol , vol.33 , pp. 1688-1696
    • Ahmed, N.1    Brawley, V.S.2    Hegde, M.3    Robertson, C.4    Ghazi, A.5    Gerken, C.6
  • 60
    • 82955207691 scopus 로고    scopus 로고
    • Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma
    • Louis CU, Savoldo B, Dotti G, Pule M, Yvon E, Myers GD, et al. Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma. Blood 2011; 118: 6050-6.
    • (2011) Blood , vol.118 , pp. 6050-6056
    • Louis, C.U.1    Savoldo, B.2    Dotti, G.3    Pule, M.4    Yvon, E.5    Myers, G.D.6
  • 61
    • 55549145071 scopus 로고    scopus 로고
    • Virusspecific Tcells engineered to coexpress tumor-specific receptors: Persistence and antitumor activity in individuals with neuroblastoma
    • Pule MA, Savoldo B, Myers GD, Rossig C, Russell HV, Dotti G, et al. Virusspecific Tcells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma. Nat Med 2008; 14: 1264-70.
    • (2008) Nat Med , vol.14 , pp. 1264-1270
    • Pule, M.A.1    Savoldo, B.2    Myers, G.D.3    Rossig, C.4    Russell, H.V.5    Dotti, G.6


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