Inflammatory cells, ceramides, and expression of proteases in perivascular adipose tissue adjacent to human abdominal aortic aneurysms

Journal of Vascular Surgery

Volumn 65, Issue 4, 2017, Pages 1171-1179.e1

  Folkesson, Maggie ^a   Vorkapic, Emina ^a   Gulbins, Erich ^b,c   Japtok, Lukasz ^d   Kleuser, Burkhard ^d   Welander, Martin ^a,e   Länne, Toste ^a,e   Wågsäter, Dick ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

^c UNIVERSITY OF CINCINNATI   (United States)

^d UNIVERSITY OF POTSDAM   (Germany)

^e Department of Clinical Immunology and Transfusion Medicine   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; CASPASE 3; CATHEPSIN K; CATHEPSIN S; CD68 ANTIGEN; CERAMIDE; CHYMASE; GELATINASE A; GELATINASE B; INTERLEUKIN 6; MACROPHAGE ELASTASE; MESSENGER RNA; NEUTROPHIL COLLAGENASE; PERILIPIN; PROTEINASE; TRYPTASE; TUMOR NECROSIS FACTOR; CEACAM8 PROTEIN, HUMAN; CELL ADHESION MOLECULE; CYTOKINE; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; LEUKOCYTE ANTIGEN; PEPTIDE HYDROLASE;

ABDOMINAL AORTA ANEURYSM; ADIPOCYTE; ADIPOSE TISSUE; ADVENTITIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTERY; CELL DEATH; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE RELEASE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MALE; MASS SPECTROMETRY; MAST CELL; MOUSE; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PERIVASCULAR ADIPOSE TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; ABDOMINAL AORTIC ANEURYSM; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; NECROSIS; PATHOLOGY;

ADIPOCYTES; ADIPOSE TISSUE; ANTIGENS, CD; AORTIC ANEURYSM, ABDOMINAL; CELL ADHESION MOLECULES; CERAMIDES; CYTOKINES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GPI-LINKED PROTEINS; HUMANS; MACROPHAGES; MAST CELLS; NECROSIS; NEUTROPHILS; PEPTIDE HYDROLASES; T-LYMPHOCYTES;

EID: 84959498261     PISSN: 07415214     EISSN: 10976809     Source Type: Journal    
DOI: 10.1016/j.jvs.2015.12.056     Document Type: Conference Paper

References (37)

1. 1 Svensjo, S., Bjorck, M., Wanhainen, A., Update on screening for abdominal aortic aneurysm: a topical review. Eur J Vasc Endovasc Surg 48 (2014), 659–667.
2. 2 Lederle, F.A., Abdominal aortic aneurysm: still no pill. Ann Intern Med 159 (2013), 852–853.
3. 3 Zatina, M.A., Zarins, C.K., Gewertz, B.L., Glagov, S., Role of medial lamellar architecture in the pathogenesis of aortic aneurysms. J Vasc Surg 1 (1984), 442–448.
4. 4 Michel, J.B., Martin-Ventura, J.L., Egido, J., Sakalihasan, N., Treska, V., Lindholt, J., et al. Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans. Cardiovasc Res 90 (2011), 18–27.
5. 5 Folkesson, M., Silveira, A., Eriksson, P., Swedenborg, J., Protease activity in the multi-layered intra-luminal thrombus of abdominal aortic aneurysms. Atherosclerosis 218 (2011), 294–299.
6. 6 Sakalihasan, N., Limet, R., Defawe, O.D., Abdominal aortic aneurysm. Lancet 365 (2005), 1577–1589.
7. 7 Chatterjee, T.K., Stoll, L.L., Denning, G.M., Harrelson, A., Blomkalns, A.L., Idelman, G., et al. Proinflammatory phenotype of perivascular adipocytes: influence of high-fat feeding. Circ Res 104 (2009), 541–549.
8. 8 Wolinsky, H., Glagov, S., Comparison of abdominal and thoracic aortic medial structure in mammals. Deviation of man from the usual pattern. Circ Res 25 (1969), 677–686.
9. 9 Sano, M., Sasaki, T., Hirakawa, S., Sakabe, J., Ogawa, M., Baba, S., et al. Lymphangiogenesis and angiogenesis in abdominal aortic aneurysm. PLoS One, 9, 2014, e89830.
10. 10 Satta, J., Soini, Y., Mosorin, M., Juvonen, T., Angiogenesis is associated with mononuclear inflammatory cells in abdominal aortic aneurysms. Ann Chir Gynaecol 87 (1998), 40–42.
11. 11 Villacorta, L., Chang, L., The role of perivascular adipose tissue in vasoconstriction, arterial stiffness, and aneurysm. Horm Mol Biol Clin Investig 21 (2015), 137–147.
12. 12 Gu, P., Xu, A., Interplay between adipose tissue and blood vessels in obesity and vascular dysfunction. Rev Endocr Metab Disord 14 (2013), 49–58.
13. 13 Verhagen, S.N., Visseren, F.L., Perivascular adipose tissue as a cause of atherosclerosis. Atherosclerosis 214 (2011), 3–10.
14. 14 Lehman, S.J., Massaro, J.M., Schlett, C.L., O'Donnell, C.J., Hoffmann, U., Fox, C.S., Periaortic fat, cardiovascular disease risk factors, and aortic calcification: the Framingham Heart Study. Atherosclerosis 210 (2010), 656–661.
15. 15 Thanassoulis, G., Massaro, J.M., Corsini, E., Rogers, I., Schlett, C.L., Meigs, J.B., et al. Periaortic adipose tissue and aortic dimensions in the Framingham Heart Study. J Am Heart Assoc, 1, 2012, e000885.
16. 16 Lee, H.Y., Despres, J.P., Koh, K.K., Perivascular adipose tissue in the pathogenesis of cardiovascular disease. Atherosclerosis 230 (2013), 177–184.
17. 17 Takagi, H., Watanabe, T., Mizuno, Y., Kawai, N., Umemoto, T., All-Literature Investigation of Cardiovascular Evidence Group. Circulating interleukin-6 levels are associated with abdominal aortic aneurysm presence: a meta-analysis and meta-regression of case-control studies. Ann Vasc Surg 28 (2014), 1913–1922.
18. 18 Kolak, M., Westerbacka, J., Velagapudi, V.R., Wagsater, D., Yetukuri, L., Makkonen, J., et al. Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity. Diabetes 56 (2007), 1960–1968.
19. 19 Shah, C., Yang, G., Lee, I., Bielawski, J., Hannun, Y.A., Samad, F., Protection from high fat diet-induced increase in ceramide in mice lacking plasminogen activator inhibitor 1. J Biol Chem 283 (2008), 13538–13548.
20. 20 Auge, N., Negre-Salvayre, A., Salvayre, R., Levade, T., Sphingomyelin metabolites in vascular cell signaling and atherogenesis. Prog Lipid Res 39 (2000), 207–229.
21. 21 Hetz, C.A., Hunn, M., Rojas, P., Torres, V., Leyton, L., Quest, A.F., Caspase-dependent initiation of apoptosis and necrosis by the Fas receptor in lymphoid cells: onset of necrosis is associated with delayed ceramide increase. J Cell Sci 115 (2002), 4671–4683.
22. 22 Gulbins, E., Li, P.L., Physiological and pathophysiological aspects of ceramide. Am J Physiol Regul Integr Comp Physiol 290 (2006), R11–R26.
23. 23 Auge, N., Maupas-Schwalm, F., Elbaz, M., Thiers, J.C., Waysbort, A., Itohara, S., et al. Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation. Circulation 110 (2004), 571–578.
24. 24 Vorkapic, E., Lundberg, A.M., Mayranpaa, M.I., Eriksson, P., Wagsater, D., TRIF adaptor signaling is important in abdominal aortic aneurysm formation. Atherosclerosis 241 (2015), 561–568.
25. 25 Pewzner-Jung, Y., Tavakoli Tabazavareh, S., Grassme, H., Becker, K.A., Japtok, L., Steinmann, J., et al. Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa. EMBO Mol Med 6 (2014), 1205–1214.
26. 26 Braunersreuther, V., Mach, F., Steffens, S., The specific role of chemokines in atherosclerosis. Thromb Haemost 97 (2007), 714–721.
27. 27 Mayranpaa, M.I., Trosien, J.A., Fontaine, V., Folkesson, M., Kazi, M., Eriksson, P., et al. Mast cells associate with neovessels in the media and adventitia of abdominal aortic aneurysms. J Vasc Surg 50 (2009), 388–395 discussion: 395-6.
28. 28 Shi, H.T., Wang, Y., Jia, L.X., Qin, Y.W., Liu, Y., Li, H.H., et al. Cathepsin S contributes to macrophage migration via degradation of elastic fibre integrity to facilitate vein graft neointimal hyperplasia. Cardiovasc Res 101 (2014), 454–463.
29. 29 Sun, J., Sukhova, G.K., Zhang, J., Chen, H., Sjoberg, S., Libby, P., et al. Cathepsin L activity is essential to elastase perfusion-induced abdominal aortic aneurysms in mice. Arterioscler Thromb Vasc Biol 31 (2011), 2500–2508.
30. 30 Rossi, C., Santini, E., Chiarugi, M., Salvati, A., Comassi, M., Vitolo, E., et al. The complex P2X7 receptor/inflammasome in perivascular fat tissue of heavy smokers. Eur J Clin Invest 44 (2014), 295–302.
31. 31 Maceyka, M., Spiegel, S., Sphingolipid metabolites in inflammatory disease. Nature 510 (2014), 58–67.
32. 32 Jiang, X.C., Paultre, F., Pearson, T.A., Reed, R.G., Francis, C.K., Lin, M., et al. Plasma sphingomyelin level as a risk factor for coronary artery disease. Arterioscler Thromb Vasc Biol 20 (2000), 2614–2618.
33. 33 Kasumov, T., Li, L., Li, M., Gulshan, K., Kirwan, J.P., Liu, X., et al. Ceramide as a mediator of non-alcoholic Fatty liver disease and associated atherosclerosis. PLoS One, 10, 2015, e0126910.
34. 34 Haimovitz-Friedman, A., Cordon-Cardo, C., Bayoumy, S., Garzotto, M., McLoughlin, M., Gallily, R., et al. Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation. J Exp Med 186 (1997), 1831–1841.
35. 35 Guzik, T.J., Hoch, N.E., Brown, K.A., McCann, L.A., Rahman, A., Dikalov, S., et al. Role of the T-cell in the genesis of angiotensin II induced hypertension and vascular dysfunction. J Exp Med 204 (2007), 2449–2460.
36. 36 Siegmann, N., Worbs, D., Effinger, F., Bormann, T., Gebhardt, M., Ulrich, M., et al. Invariant natural killer T (iNKT) cells prevent autoimmunity, but induce pulmonary inflammation in cystic fibrosis. Cell Physiol Biochem 34 (2014), 56–70.
37. 37 Kazi, M., Thyberg, J., Religa, P., Roy, J., Eriksson, P., Hedin, U., et al. Influence of intraluminal thrombus on structural and cellular composition of abdominal aortic aneurysm wall. J Vasc Surg 38 (2003), 1283–1292.