Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk

Circulation: Cardiovascular Genetics

Volumn 9, Issue 1, 2016, Pages 64-70

  Yu, Bing ^a   Pulit, Sara L ^b   Hwang, Shih Jen ^c   Brody, Jennifer A ^e   Amin, Najaf ^f   Auer, Paul L ^g   Bis, Joshua C ^h   Boerwinkle, Eric ^e   Burke, Gregory L ^c,v   Chakravarti, Aravinda ^d,w   Correa, Adolfo ^e   Dreisbach, Albert W ^c   Franco, Oscar H ^e   Ehret, Georg B ^b   Franceschini, Nora ^e,i   Hofman, Albert ^c,t   Lin, Dan Yu ^e,u   Metcalf, Ginger A ^f,g   Musani, Solomon K ^j   Muzny, Donna ^k   Palmas, Walter ^l,q   Raffel, Leslie ^c   Reiner, Alex ^e,g   Rice, Ken ^g,p   Rotter, Jerome I ^m   Veeraraghavan, Narayanan ⁿ   Fox, Ervin ^e   Guo, Xiuqing ^f,r   North, Kari E ^o   Gibbs, Richard A ^g   Van Duijn, Cornelia M ^g,s   Psaty, Bruce M ^d   Levy, Daniel ^e   Newton Cheh, Christopher ^g   Morrison, Alanna C ^a   more..

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d FRAMINGHAM HEART STUDY   (United States)

^e NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^f Cardiovascular Health Research Unit   (United States)

^g Department of Biostatistics ^*  (United States)

^h UNIVERSITY OF WASHINGTON   (United States)

ⁱ ERASMUS MEDICAL CENTER   (Netherlands)

^j UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^k BAYLOR COLLEGE OF MEDICINE   (United States)

^l WAKE FOREST SCHOOL OF MEDICINE   (United States)

^m JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁿ UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^o GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^p IL   (United States)

^q NewYork Presbyterian Hospital   (United States)

^r UNIVERSITY OF CALIFORNIA   (United States)

^s Fred Hutchinson Cancer Research Center   (United States)

^t UCLA MEDICAL CENTER   (United States)

^u CENTER FOR HEALTH STUDIES   (United States)

^v BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^w MASSACHUSETTS GENERAL HOSPITAL   (United States)

more..

Author keywords

blood pressure; exome; genetic variation; genome wide association study; hypertension

Indexed keywords

ADULT; ARTICLE; BLOOD PRESSURE REGULATION; CARDIAC PATIENT; CARDIOVASCULAR RISK; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE FREQUENCY; GENE SEQUENCE; GENETIC CODE; GENETIC SCREENING; GENETIC VARIABILITY; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PULSE PRESSURE; ALLELE; BLACK PERSON; BLOOD PRESSURE; CAUCASIAN; EXOME; FEMALE; GENETICS; MALE; META ANALYSIS; RISK FACTOR;

CHLORIDE CHANNEL; CLCN6 PROTEIN, HUMAN;

AFRICAN CONTINENTAL ANCESTRY GROUP; ALLELES; BLOOD PRESSURE; CHLORIDE CHANNELS; EUROPEAN CONTINENTAL ANCESTRY GROUP; EXOME; FEMALE; GENE FREQUENCY; HUMANS; HYPERTENSION; MALE; RISK FACTORS;

EID: 84959482057     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.115.001215     Document Type: Article

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