A novel Flt3-deficient HIS mouse model with selective enhancement of human DC development

European Journal of Immunology

Volumn 46, Issue 5, 2016, Pages 1291-1299

  Li, Yan ^a,b   Mention, Jean Jacques ^a,b   Court, Nathalie ^a,b   Masse Ranson, Guillemette ^a,b   Toubert, Antoine ^c   Spits, Hergen ^d   Legrand, Nicolas ^e   Corcuff, Erwan ^e   Strick Marchand, Helene ^a,b   Di Santo, James P ^a,b  

^a INSTITUT PASTEUR   (France)

^b INSTITUT PASTEUR   (France)

^c SAINT LOUIS HOSPITAL   (France)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

^e Axenis S A S   (France)

Author keywords

Adjuvants; Cytokines; Dendritic cells; Humanized mice; Innate immunity

Indexed keywords

CD135 ANTIGEN; CD34 ANTIGEN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 12; INTERLEUKIN 2 RECEPTOR GAMMA; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; PROTEIN; PROTEIN FLK2; RAG2 PROTEIN; RANTES; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; FLT3 PROTEIN, MOUSE; IMMUNOLOGICAL ADJUVANT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CD3+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; HUMAN IMMUNE SYSTEM; IMMUNE SYSTEM; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; MOUSE; MOUSE MODEL; MOUSE STRAIN; NATURAL KILLER CELL; NATURAL KILLER T CELL; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; T LYMPHOCYTE; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL DIFFERENTIATION; DEFICIENCY; GENETICS; HOMEOSTASIS; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; PHYSIOLOGY; TRANSGENIC MOUSE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CELL DIFFERENTIATION; DENDRITIC CELLS; FMS-LIKE TYROSINE KINASE 3; HOMEOSTASIS; HUMANS; IMMUNITY, INNATE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; MYELOID CELLS; NATURAL KILLER T-CELLS; T-LYMPHOCYTES;

EID: 84959473195     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201546132     Document Type: Article

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