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Volumn 24, Issue 2, 2016, Pages 230-239

Virus-mediated EpoR76E therapy slows optic nerve axonopathy in experimental glaucoma

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; ERYTHROPOIETIN RECEPTOR 76E; PARVOVIRUS VECTOR; UNCLASSIFIED DRUG; EPO PROTEIN, HUMAN;

EID: 84959465031     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2015.198     Document Type: Article
Times cited : (37)

References (41)
  • 1
    • 1842556467 scopus 로고    scopus 로고
    • Current management of glaucoma
    • Schwartz, K and Budenz, D (2004). Current management of glaucoma. Curr Opin Ophthalmol 15: 119-126.
    • (2004) Curr Opin Ophthalmol , vol.15 , pp. 119-126
    • Schwartz, K.1    Budenz, D.2
  • 2
    • 20144369022 scopus 로고    scopus 로고
    • Noncompliance with ocular hypotensive treatment in patients with glaucoma or ocular hypertension an evidence-based review
    • Olthoff, CM, Schouten, JS, van de Borne, BW and Webers, CA (2005). Noncompliance with ocular hypotensive treatment in patients with glaucoma or ocular hypertension an evidence-based review. Ophthalmology 112: 953-961.
    • (2005) Ophthalmology , vol.112 , pp. 953-961
    • Olthoff, C.M.1    Schouten, J.S.2    Van De Borne, B.W.3    Webers, C.A.4
  • 3
    • 84874557004 scopus 로고    scopus 로고
    • Erythropoietin: Multiple targets, actions and modifying influences for biological and clinical consideration
    • Broxmeyer, HE (2013). Erythropoietin: multiple targets, actions and modifying influences for biological and clinical consideration. J Exp Med 210: 205-208.
    • (2013) J Exp Med , vol.210 , pp. 205-208
    • Broxmeyer, H.E.1
  • 5
    • 84919435787 scopus 로고    scopus 로고
    • Evidence that erythropoietin modulates neuroinflammation through differential action on neurons, astrocytes and microglia
    • Bond, WS and Rex, TS (2014). Evidence that erythropoietin modulates neuroinflammation through differential action on neurons, astrocytes and microglia. Front Immunol 5: 523.
    • (2014) Front Immunol , vol.5 , pp. 523
    • Bond, W.S.1    Rex, T.S.2
  • 6
    • 0025368286 scopus 로고
    • The pharmacokinetics of recombinant human erythropoietin after intravenous and subcutaneous administration to healthy subjects
    • Salmonson, T, Danielson, BG and Wikström, B (1990). The pharmacokinetics of recombinant human erythropoietin after intravenous and subcutaneous administration to healthy subjects. Br J Clin Pharmacol 29: 709-713.
    • (1990) Br J Clin Pharmacol , vol.29 , pp. 709-713
    • Salmonson, T.1    Danielson, B.G.2    Wikström, B.3
  • 7
    • 80055093372 scopus 로고    scopus 로고
    • Systemic adeno-Associated virus-mediated gene therapy preserves retinal ganglion cells and visual function in DBA/2J glaucomatous mice
    • Sullivan, TA, Geisert, EE, Hines-Beard, J and Rex, TS (2011). Systemic adeno-Associated virus-mediated gene therapy preserves retinal ganglion cells and visual function in DBA/2J glaucomatous mice. Hum Gene Ther 22: 1191-1200.
    • (2011) Hum Gene Ther , vol.22 , pp. 1191-1200
    • Sullivan, T.A.1    Geisert, E.E.2    Hines-Beard, J.3    Rex, T.S.4
  • 8
    • 79954574434 scopus 로고    scopus 로고
    • Systemic gene delivery protects the photoreceptors in the retinal degeneration slow mouse
    • Sullivan, T, Kodali, K and Rex, TS (2011). Systemic gene delivery protects the photoreceptors in the retinal degeneration slow mouse. Neurochem Res 36: 613-618.
    • (2011) Neurochem Res , vol.36 , pp. 613-618
    • Sullivan, T.1    Kodali, K.2    Rex, T.S.3
  • 9
    • 84857796123 scopus 로고    scopus 로고
    • Dose-Dependent treatment of optic nerve crush by exogenous systemic mutant erythropoietin
    • Sullivan, TA, Geisert, EE, Templeton, JP and Rex, TS (2012). Dose-Dependent treatment of optic nerve crush by exogenous systemic mutant erythropoietin. Exp Eye Res 96: 36-41.
    • (2012) Exp Eye Res , vol.96 , pp. 36-41
    • Sullivan, T.A.1    Geisert, E.E.2    Templeton, J.P.3    Rex, T.S.4
  • 10
    • 7044228129 scopus 로고    scopus 로고
    • Systemic but not intraocular Epo gene transfer protects the retina from light-And genetic-induced degeneration
    • Rex, TS, Allocca, M, Domenici, L, Surace, EM, Maguire, AM, Lyubarsky, A, et al. (2004). Systemic but not intraocular Epo gene transfer protects the retina from light-And genetic-induced degeneration. Mol Ther 10: 855-861.
    • (2004) Mol Ther , vol.10 , pp. 855-861
    • Rex, T.S.1    Allocca, M.2    Domenici, L.3    Surace, E.M.4    Maguire, A.M.5    Lyubarsky, A.6
  • 11
    • 84874189407 scopus 로고    scopus 로고
    • A single intramuscular injection of rAAV-mediated mutant erythropoietin protects against MPTP-induced parkinsonism
    • Dhanushkodi, A, Akano, EO, Roguski, EE, Xue, Y, Rao, SK, Matta, SG, et al. (2013). A single intramuscular injection of rAAV-mediated mutant erythropoietin protects against MPTP-induced parkinsonism. Genes Brain Behav 12: 224-233.
    • (2013) Genes Brain Behav , vol.12 , pp. 224-233
    • Dhanushkodi, A.1    Akano, E.O.2    Roguski, E.E.3    Xue, Y.4    Rao, S.K.5    Matta, S.G.6
  • 12
    • 84888126198 scopus 로고    scopus 로고
    • Identification of a therapeutic dose of continuously delivered erythropoietin in the eye using an inducible promoter system
    • Hines-Beard, J, Desai, S, Haag, R, Esumi, N, D'Surney, L, Parker, S, et al. (2013). Identification of a therapeutic dose of continuously delivered erythropoietin in the eye using an inducible promoter system. Curr Gene Ther 13: 275-281.
    • (2013) Curr Gene Ther , vol.13 , pp. 275-281
    • Hines-Beard, J.1    Desai, S.2    Haag, R.3    Esumi, N.4    D'Surney, L.5    Parker, S.6
  • 13
    • 75749149418 scopus 로고    scopus 로고
    • The microbead occlusion model: A paradigm for induced ocular hypertension in rats and mice
    • Carlson, BJ, Crish, SD and Calkins, DJ.
    • Sappington, RM, Carlson, BJ, Crish, SD and Calkins, DJ (2010). The microbead occlusion model: a paradigm for induced ocular hypertension in rats and mice. Invest Ophthalmol Vis Sci 51: 207-216.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 207-216
    • Sappington, R.M.1
  • 14
    • 84894415477 scopus 로고    scopus 로고
    • Absence of transient receptor potential vanilloid-1 accelerates stress-induced axonopathy in the optic projection
    • Ward, NJ, Ho, KW, Lambert, WS, Weitlauf, C and Calkins, DJ (2014). Absence of transient receptor potential vanilloid-1 accelerates stress-induced axonopathy in the optic projection. J Neurosci 34: 3161-3170.
    • (2014) J Neurosci , vol.34 , pp. 3161-3170
    • Ward, N.J.1    Ho, K.W.2    Lambert, W.S.3    Weitlauf, C.4    Calkins, D.J.5
  • 15
    • 0037853141 scopus 로고    scopus 로고
    • By altering ocular immune privilege, bone marrow-Derived cells pathogenically contribute to DBA/2J pigmentary glaucoma
    • Mo, JS, Anderson, MG, Gregory, M, Smith, RS, Savinova, OV, Serreze, DV, et al. (2003). By altering ocular immune privilege, bone marrow-Derived cells pathogenically contribute to DBA/2J pigmentary glaucoma. J Exp Med 197: 1335-1344.
    • (2003) J Exp Med , vol.197 , pp. 1335-1344
    • Mo, J.S.1    Anderson, M.G.2    Gregory, M.3    Smith, R.S.4    Savinova, O.V.5    Serreze, D.V.6
  • 16
    • 40849088250 scopus 로고    scopus 로고
    • Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma
    • Buckingham, BP, Inman, DM, Lambert, W, Oglesby, E, Calkins, DJ, Steele, MR, et al. (2008). Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma. J Neurosci 28: 2735-2744.
    • (2008) J Neurosci , vol.28 , pp. 2735-2744
    • Buckingham, B.P.1    Inman, D.M.2    Lambert, W.3    Oglesby, E.4    Calkins, D.J.5    Steele, M.R.6
  • 18
    • 84867400662 scopus 로고    scopus 로고
    • Critical pathogenic events underlying progression of neurodegeneration in glaucoma
    • Calkins, DJ (2012). Critical pathogenic events underlying progression of neurodegeneration in glaucoma. Prog Retin Eye Res 31: 702-719.
    • (2012) Prog Retin Eye Res , vol.31 , pp. 702-719
    • Calkins, D.J.1
  • 21
    • 84870812784 scopus 로고    scopus 로고
    • Failure of axonal transport induces a spatially coincident increase in astrocyte BDNF prior to synapse loss in a central target
    • Crish, SD, Dapper, JD, MacNamee, SE, Balaram, P, Sidorova, TN, Lambert, WS, et al. (2013). Failure of axonal transport induces a spatially coincident increase in astrocyte BDNF prior to synapse loss in a central target. Neuroscience 229: 55-70.
    • (2013) Neuroscience , vol.229 , pp. 55-70
    • Crish, S.D.1    Dapper, J.D.2    MacNamee, S.E.3    Balaram, P.4    Sidorova, T.N.5    Lambert, W.S.6
  • 22
    • 84881116180 scopus 로고    scopus 로고
    • Proximal inhibition of p38 MAPK stress signaling prevents distal axonopathy
    • Dapper, JD, Crish, SD, Pang, IH and Calkins, DJ (2013). Proximal inhibition of p38 MAPK stress signaling prevents distal axonopathy. Neurobiol Dis 59: 26-37.
    • (2013) Neurobiol Dis , vol.59 , pp. 26-37
    • Dapper, J.D.1    Crish, S.D.2    Pang, I.H.3    Calkins, D.J.4
  • 23
    • 78651286291 scopus 로고    scopus 로고
    • Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons
    • Lambert, WS, Ruiz, L, Crish, SD, Wheeler, LA and Calkins, DJ (2011). Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons. Mol Neurodegener 6: 4.
    • (2011) Mol Neurodegener , vol.6 , pp. 4
    • Lambert, W.S.1    Ruiz, L.2    Crish, S.D.3    Wheeler, L.A.4    Calkins, D.J.5
  • 24
    • 44349170706 scopus 로고    scopus 로고
    • Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection
    • Zincarelli, C, Soltys, S, Rengo, G and Rabinowitz, JE (2008). Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection. Mol Ther 16: 1073-1080.
    • (2008) Mol Ther , vol.16 , pp. 1073-1080
    • Zincarelli, C.1    Soltys, S.2    Rengo, G.3    Rabinowitz, J.E.4
  • 25
    • 33645420956 scopus 로고    scopus 로고
    • Quantitative correlation of optic nerve pathology with ocular pressure and corneal thickness in the DBA/2 mouse model of glaucoma
    • Inman, DM, Sappington, RM, Horner, PJ and Calkins, DJ (2006). Quantitative correlation of optic nerve pathology with ocular pressure and corneal thickness in the DBA/2 mouse model of glaucoma. Invest Ophthalmol Vis Sci 47: 986-996.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 986-996
    • Inman, D.M.1    Sappington, R.M.2    Horner, P.J.3    Calkins, D.J.4
  • 26
    • 80051733360 scopus 로고    scopus 로고
    • Postnatal elongation of eye size in DBA/2J mice compared with C57BL/6J mice: In vivo analysis with whole-Eye OCT
    • Chou, TH, Kocaoglu, OP, Borja, D, Ruggeri, M, Uhlhorn, SR, Manns, F, et al. (2011). Postnatal elongation of eye size in DBA/2J mice compared with C57BL/6J mice: in vivo analysis with whole-Eye OCT. Invest Ophthalmol Vis Sci 52: 3604-3612.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 3604-3612
    • Chou, T.H.1    Kocaoglu, O.P.2    Borja, D.3    Ruggeri, M.4    Uhlhorn, S.R.5    Manns, F.6
  • 27
    • 15444363036 scopus 로고    scopus 로고
    • High-Dose radiation with bone marrow transfer prevents neurodegeneration in an inherited glaucoma
    • Anderson, MG, Libby, RT, Gould, DB, Smith, RS and John, SW (2005). High-Dose radiation with bone marrow transfer prevents neurodegeneration in an inherited glaucoma. Proc Natl Acad Sci USA 102: 4566-4571.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4566-4571
    • Anderson, M.G.1    Libby, R.T.2    Gould, D.B.3    Smith, R.S.4    John, S.W.5
  • 28
    • 33750381831 scopus 로고    scopus 로고
    • Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric
    • Schlamp, CL, Li, Y, Dietz, JA, Janssen, KT and Nickells, RW (2006). Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric. BMC Neurosci 7: 66.
    • (2006) BMC Neurosci , vol.7 , pp. 66
    • Schlamp, C.L.1    Li, Y.2    Dietz, J.A.3    Janssen, K.T.4    Nickells, R.W.5
  • 29
    • 33746690523 scopus 로고    scopus 로고
    • Interleukin-6 protects retinal ganglion cells from pressure-induced death
    • Sappington, RM, Chan, M and Calkins, DJ (2006). Interleukin-6 protects retinal ganglion cells from pressure-induced death. Invest Ophthalmol Vis Sci 47: 2932-2942.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 2932-2942
    • Sappington, R.M.1    Chan, M.2    Calkins, D.J.3
  • 30
    • 84859726329 scopus 로고    scopus 로고
    • Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma
    • Howell, GR, Soto, I, Zhu, X, Ryan, M, Macalinao, DG, Sousa, GL, et al. (2012). Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma. J Clin Invest 122: 1246-1261.
    • (2012) J Clin Invest , vol.122 , pp. 1246-1261
    • Howell, G.R.1    Soto, I.2    Zhu, X.3    Ryan, M.4    MacAlinao, D.G.5    Sousa, G.L.6
  • 31
    • 84921511309 scopus 로고    scopus 로고
    • Radiation pretreatment does not protect the rat optic nerve from elevated intraocular pressureinduced injury
    • Johnson, EC, Cepurna, WO, Choi, D, Choe, TE and Morrison, JC (2015). Radiation pretreatment does not protect the rat optic nerve from elevated intraocular pressureinduced injury. Invest Ophthalmol Vis Sci 56: 412-419.
    • (2015) Invest Ophthalmol Vis Sci , vol.56 , pp. 412-419
    • Johnson, E.C.1    Cepurna, W.O.2    Choi, D.3    Choe, T.E.4    Morrison, J.C.5
  • 35
    • 77950804863 scopus 로고    scopus 로고
    • Oxidative stress markers in patients with primary open-Angle glaucoma
    • Ghanem, AA, Arafa, LF and El-Baz, A (2010). Oxidative stress markers in patients with primary open-Angle glaucoma. Curr Eye Res 35: 295-301.
    • (2010) Curr Eye Res , vol.35 , pp. 295-301
    • Ghanem, A.A.1    Arafa, L.F.2    El-Baz, A.3
  • 37
    • 56549118858 scopus 로고    scopus 로고
    • Risk factors for glaucoma onset and progression
    • Coleman, AL and Miglior, S (2008). Risk factors for glaucoma onset and progression. Surv Ophthalmol 53 (suppl. 1): S3-10.
    • (2008) Surv Ophthalmol , vol.53 , pp. S3-S10
    • Coleman, A.L.1    Miglior, S.2
  • 38
    • 78751489896 scopus 로고    scopus 로고
    • Early microglia activation in a mouse model of chronic glaucoma
    • Bosco, A, Steele, MR and Vetter, ML (2011). Early microglia activation in a mouse model of chronic glaucoma. J Comp Neurol 519: 599-620.
    • (2011) J Comp Neurol , vol.519 , pp. 599-620
    • Bosco, A.1    Steele, M.R.2    Vetter, M.L.3
  • 40
    • 84929043462 scopus 로고    scopus 로고
    • Safety and angiogenic effects of systemic gene delivery of a modified erythropoietin
    • de Lucas Cerrillo, AM, Bond, WS and Rex, TS (2015). Safety and angiogenic effects of systemic gene delivery of a modified erythropoietin. Gene Ther 22: 365-373.
    • (2015) Gene Ther , vol.22 , pp. 365-373
    • De Lucas Cerrillo, A.M.1    Bond, W.S.2    Rex, T.S.3
  • 41
    • 17544383607 scopus 로고    scopus 로고
    • Gene transfer into skeletal muscle using novel AAV serotypes
    • Louboutin, JP, Wang, L and Wilson, JM (2005). Gene transfer into skeletal muscle using novel AAV serotypes. J Gene Med 7: 442-451.
    • (2005) J Gene Med , vol.7 , pp. 442-451
    • Louboutin, J.P.1    Wang, L.2    Wilson, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.