Echo time optimization for J-difference editing of glutathione at 3T

Magnetic Resonance in Medicine

Volumn 77, Issue 2, 2017, Pages 498-504

  Chan, Kimberly L ^a,b   Puts, Nicolaas A J ^a,b   Snoussi, Karim ^a,b   Harris, Ashley D ^a,b   Barker, Peter B ^a,b   Edden, Richard A E ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KENNEDY KRIEGER INSTITUTE   (United States)

Author keywords

brain; echo time; edited MRS; glutathione; GSH

Indexed keywords

BRAIN; MAGNETIC RESONANCE; PHANTOMS;

AMPLITUDE MODULATED; ECHO TIME; EDITED MRS; FREQUENCY MODULATED; GLUTATHIONES; IN-VIVO MEASUREMENT; INTERNATIONAL SOCIETY; TRANSVERSE RELAXATION;

PEPTIDES;

GLUTATHIONE;

ADULT; ARTICLE; CHEMICAL PARAMETERS; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; ECHO TIME; FEMALE; HUMAN; HUMAN EXPERIMENT; IMAGING PHANTOM; IN VIVO STUDY; INVESTIGATIVE PROCEDURES; J DIFFERENCE EDITING; MALE; NORMAL HUMAN; PROCESS MODEL; PROCESS OPTIMIZATION; SIGNAL PROCESSING; ALGORITHM; BRAIN CHEMISTRY; EVALUATION STUDY; MOLECULAR IMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

ADULT; ALGORITHMS; BRAIN CHEMISTRY; FEMALE; GLUTATHIONE; HUMANS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MOLECULAR IMAGING; PHANTOMS, IMAGING; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SIGNAL PROCESSING, COMPUTER-ASSISTED;

EID: 84959450399     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.26122     Document Type: Article

References (45)

1. Wood SJ, Berger GE, Wellard RM, Proffitt T-M, McConchie M, Berk M, McGorry PD, Pantelis C. Medial temporal lobe glutathione concentration in first episode psychosis: a 1H-MRS investigation. Neurobiol Dis 2009;33:354–357.
2. Cooper AJ, Kristal BS. Multiple roles of glutathione in the central nervous system. Biol Chem 1997;378:793–802.
3. Matsuzawa D, Obata T, Shirayama Y, Nonaka H, Kanazawa Y, Yoshitome E, Takanashi J, Matsuda T, Shimizu E, Ikehira H, et al. Negative correlation between brain glutathione level and negative symptoms in schizophrenia: a 3T 1H-MRS study. PLoS One 2008;3:e1944
4. Lavoie S, Murray MM, Deppen P, Knyazeva M, Berk M, Boulat O, Bovet P, Bush AI, Conus P, Copolov D, et al. Glutathione precursor, N-acetyl-cysteine, improves mismatch negativity in schizophrenia patients. Neuropsychopharmacology 2008;33:2187–2199.
5. Gysin R, Kraftsik R, Sandell J, Bovet P, Chappuis C, Conus P, Deppen P, Preisig M, Ruiz V, Steullet P, et al. Impaired glutathione synthesis in schizophrenia: convergent genetic and functional evidence. Proc Natl Acad Sci U S A 2007;104:16621–16626.
6. Rosa AR, Singh N, Whitaker E, de Brito M, Lewis AM, Vieta E, Churchill GC, Geddes JR, Goodwin GM. Altered plasma glutathione levels in bipolar disorder indicates higher oxidative stress; a possible risk factor for illness onset despite normal brain-derived neurotrophic factor (BDNF) levels. Psychol Med 2014;44:2409–2418.
7. Gawryluk JW, Wang J-F, Andreazza AC, Shao L, Young LT. Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders. Int J Neuropsychopharmacol 2011;14:123–130.
8. Kulak A, Cuenod M, Do KQ. Behavioral phenotyping of glutathione-deficient mice: relevance to schizophrenia and bipolar disorder. Behav Brain Res 2012;226:563–570.
9. Sofic E, Lange KW, Jellinger K, Riederer P. Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease. Neurosci Lett 1992;142:128–130.
10. Sian J, Dexter DT, Lees AJ, Daniel S, Agid Y, Javoy-Agid F, Jenner P, Marsden CD. Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann Neurol 1994;36:348–355.
11. Martin HL, Teismann P. Glutathione—a review on its role and significance in Parkinson's disease. FASEB J 2009;23:3263–3272.
12. Dringen R. Metabolism and functions of glutathione in brain. Prog Neurobiol 2000;62:649–671.
13. Pfeuffer J, Tkác I, Provencher SW, Gruetter R. Toward an in vivo neurochemical profile: quantification of 18 metabolites in short-echo-time (1)H NMR spectra of the rat brain. J Magn Reson 1999;141:104–120.
14. Choi C, Zhao C, Dimitrov I, Douglas D, Coupland NJ, Kalra S, Hawesa H, Davis J. Measurement of glutathione in human brain at 3T using an improved double quantum filter in vivo. J Magn Reson 2009;198:160–166.
15. Trabesinger A, Weber O, Duc C, Boesiger P. Detection of glutathione in the human brain in vivo by means of double quantum coherence filtering. Magn Reson Med 1999;42:283–289.
16. Terpstra M, Vaughan TJ, Ugurbil K, Lim KO, Schulz SC, Gruetter R. Validation of glutathione quantitation from STEAM spectra against edited 1H NMR spectroscopy at 4T: application to schizophrenia. MAGMA 2005;18:276–282.
17. Emir UE, Raatz S, McPherson S, Hodges JS, Torkelson C, Tawfik P, White T, Terpstra M. Noninvasive quantification of ascorbate and glutathione concentration in the elderly human brain. NMR Biomed 2011;24:888–894.
18. Govindaraju V, Young K, Maudsley AA. Proton NMR chemical shifts and coupling constants for brain metabolites. NMR Biomed 2000;13:129–153.
19. Terpstra M, Henry P-G, Gruetter R. Measurement of reduced glutathione (GSH) in human brain using LCModel analysis of difference-edited spectra. Magn Reson Med 2003;50:19–23.
20. Kaiser LG, Marjańska M, Matson GB, Iltis I, Bush SD, Soher BJ, Mueller S, Young K. (1)H MRS detection of glycine residue of reduced glutathione in vivo 1. J Magn Reson 2010;202:259–266.
21. Bogner W, Strasser B, Povazan M, Hangel G, Gagoski B, Gruber S, Rosen B, Trattnig S, Andronesi O. 3D Mapping of Glutathione in the Human Brain via Real-Time Motion Corrected MEGA-LASER MRSI. In Proceedings of the 23rd Annual Meeting of ISMRM, Toronto, Canada, 2015. Abstract 0988.
22. Sailasuta N, Iwata Y, Nakajima S, Chavez S, Caravaggio F, Plitman E, De Luca V, Chung JK, Gerretsen P, Remington G. Lower Glutathione Levels in the Anterior Cingulate Cortex of Patients with Schizophrenia: A Preliminary 3T 1H-MRS Study. In Proceedings of the 23rd Annual Meeting of ISMRM, Toronto, Canada, 2015. Abstract 3562.
23. Weiduschat N, Mao X, Hupf J, Armstrong N, Kang G, Lange DJ, Mitsumoto H, Shungu DC. Motor cortex glutathione deficit in ALS measured in vivo with the J-editing technique. Neuroscience Letters 2014;570:102–107.
24. Satoh T, Yoshioka Y. Contribution of reduced and oxidized glutathione to signals detected by magnetic resonance spectroscopy as indicators of local brain redox state. Neuroscience Res 2006;55:34–39.
25. An L, Zhang Y, Thomasson DM, Latour LL, Baker EH, Shen J, Warach S. Measurement of glutathione in normal volunteers and stroke patients at 3T using J-difference spectroscopy with minimized subtraction errors. J Magn Reson Imaging 2009;30:263–270.
26. Nehzad FS, Anton A, Deakin B, Williams S. Glutathione Cannot Be Quantified Reliably from Short Echo PRESS Spectra. In Proceedings of the 23rd Annual Meeting of ISMRM, Toronto, Canada, 2015. Abstract 1952.
27. Rothman DL, Petroff OA, Behar KL, Mattson RH. Localized 1H NMR measurements of gamma-aminobutyric acid in human brain in vivo. Proc Natl Acad Sci U S A 1993;90:5662–5666.
28. Mescher M, Merkle H, Kirsch J, Garwood M, Gruetter R. Simultaneous in vivo spectral editing and water suppression. NMR Biomed 1998;11:266–272.
29. Edden RAE, Barker PB. If J doesn't evolve, it won't J-resolve: J-PRESS with bandwidth-limited refocusing pulses. Magn Reson Med 2011;65:1509–1514.
30. Murdoch JB, Lent AH, Kritzer MR. Computer-optimized narrowband pulses for multislice imaging. 1987;74:226–263.
31. Near J, Evans CJ, Puts NAJ, Barker PB, Edden RAE. J-difference editing of gamma-aminobutyric acid (GABA): simulated and experimental multiplet patterns. Magn Reson Med 2013;70:1183–1191.
32. Yablonskiy DA, Neil JJ, Raichle ME, Ackerman JJ. Homonuclear J coupling effects in volume localized NMR spectroscopy: pitfalls and solutions. Magn Reson Med 1998;39:169–178.
33. Thompson RB, Allen PS. Sources of variability in the response of coupled spins to the PRESS sequence and their potential impact on metabolite quantification. Magn Reson Med 1999;41:1162–1169.
34. Yahya A, Mädler B, Fallone BG. Exploiting the chemical shift displacement effect in the detection of glutamate and glutamine (Glx) with PRESS. J Magn Reson 2008;191:120–127.
35. Kaiser LG, Young K, Meyerhoff DJ, Mueller SG, Matson GB. A detailed analysis of localized J-difference GABA editing: theoretical and experimental study at 4 T. NMR Biomed 2008;21:22–32.
36. Edden RAE, Barker PB. Spatial effects in the detection of gamma-aminobutyric acid: improved sensitivity at high fields using inner volume saturation. Magn Reson Med 2007;58:1276–1282.
37. Emir UE, Deelchand D, Henry P-G, Terpstra M. Noninvasive quantification of T2 and concentrations of ascorbate and glutathione in the human brain from the same double-edited spectra. NMR Biomed 2011;24:263–269.
38. Edden RAE, Intrapiromkul J, Zhu H, Cheng Y, Barker PB. Measuring T2 in vivo with J-difference editing: application to GABA at 3 Tesla. J Magn Reson Imaging 2012;35:229–234.
39. Henning A, Fuchs A, Murdoch JB, Boesiger P. Slice-selective FID acquisition, localized by outer volume suppression (FIDLOVS) for 1H-MRSI of the human brain at 7 T with minimal signal loss. 2009;22:683–696.
40. Tkáč I, Starčuk Z, Choi IY, Gruetter R. In vivo 1H NMR spectroscopy of rat brain at 1 ms echo time. Magn Reson Med 1999;41:649–656.
41. Edden RAE, Puts NAJ, Harris AD, Barker PB, Evans CJ. Gannet: a batch-processing tool for the quantitative analysis of gamma-aminobutyric acid-edited MR spectroscopy spectra. J Magn Reson Imaging 2014;1452:1445–1452.
42. Near J, Edden R, Evans CJ, Paquin R, Harris A, Jezzard P. Frequency and phase drift correction of magnetic resonance spectroscopy data by spectral registration in the time domain. Magn Reson Med 2014;50:44–50.
43. Soher BJ, Hurd RE, Sailasuta N, Barker PB. Quantitation of automated single-voxel proton MRS using cerebral water as an internal reference. Magn Reson Med 1996;36:335–339.
44. Edden RAE, Schär M, Hillis AE, Barker PB. Optimized detection of lactate at high fields using inner volume saturation. Magn Reson Med 2006;56:912–917.
45. Terpstra M, Marjanska M, Henry PG, Tkáč I, Gruetter R. Detection of an antioxidant profile in the human brain in vivo via double editing with MEGA-PRESS. Magn Reson Med 2006;56:1192–1199.