-
1
-
-
84919418334
-
Updating the natural history of diabetic nephropathy
-
Pugliese G. Updating the natural history of diabetic nephropathy. Acta Diabetol. 2014;51:905-915.
-
(2014)
Acta Diabetol
, vol.51
, pp. 905-915
-
-
Pugliese, G.1
-
2
-
-
84867576816
-
Podocyte detachment and reduced glomerular capillary endothelial fenestration promote kidney disease in type 2 diabetic nephropathy
-
Weil EJ, Lemley KV, Mason CC, et al. Podocyte detachment and reduced glomerular capillary endothelial fenestration promote kidney disease in type 2 diabetic nephropathy. Kidney Int. 2012;82: 1010-1017.
-
(2012)
Kidney Int
, vol.82
, pp. 1010-1017
-
-
Weil, E.J.1
Lemley, K.V.2
Mason, C.C.3
-
3
-
-
84906939393
-
Diabetic nephropathy-emerging epigenetic mechanisms
-
Kato M, Natarajan R. Diabetic nephropathy-emerging epigenetic mechanisms. Nat Rev Nephrol. 2014;10:517-530.
-
(2014)
Nat Rev Nephrol
, vol.10
, pp. 517-530
-
-
Kato, M.1
Natarajan, R.2
-
4
-
-
68149170224
-
Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes
-
Ninomiya T, Perkovic V, de Galan BE, et al. Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes. J Am Soc Nephrol. 2009;20:1813-1821.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 1813-1821
-
-
Ninomiya, T.1
Perkovic, V.2
De Galan, B.E.3
-
5
-
-
80051947708
-
Clinical significance of nonalbuminuric renal impairment in type 2 diabetes
-
Penno G, Solini A, Bonora E, et al. Clinical significance of nonalbuminuric renal impairment in type 2 diabetes. J Hypertens. 2011; 29:1802-1809.
-
(2011)
J Hypertens
, vol.29
, pp. 1802-1809
-
-
Penno, G.1
Solini, A.2
Bonora, E.3
-
6
-
-
84928137435
-
A high-performance liquid chromatography-tandem mass spectrometry-based targeted metabolomics kidney dysfunction marker panel in human urine
-
Klepacki J, Klawitter J, Klawitter J, Thurman JM, Christians U. A high-performance liquid chromatography-tandem mass spectrometry-based targeted metabolomics kidney dysfunction marker panel in human urine. Clin Chim Acta. 2015;446:43-53.
-
(2015)
Clin Chim Acta
, vol.446
, pp. 43-53
-
-
Klepacki, J.1
Klawitter, J.2
Klawitter, J.3
Thurman, J.M.4
Christians, U.5
-
7
-
-
84901191182
-
Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease
-
Nkuipou-Kenfack E, Duranton F, Gayrard N, et al. Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease. PLoS One. 2014;9:e96955.
-
(2014)
PLoS One
, vol.9
, pp. e96955
-
-
Nkuipou-Kenfack, E.1
Duranton, F.2
Gayrard, N.3
-
8
-
-
84923773052
-
Serum metabolomic profiling and incident CKD among African Americans
-
Yu B, Zheng Y, Nettleton JA, Alexander D, Coresh J, Boerwinkle E. Serum metabolomic profiling and incident CKD among African Americans. Clin J Am Soc Nephrol. 2014;9:1410-1417.
-
(2014)
Clin J Am Soc Nephrol
, vol.9
, pp. 1410-1417
-
-
Yu, B.1
Zheng, Y.2
Nettleton, J.A.3
Alexander, D.4
Coresh, J.5
Boerwinkle, E.6
-
9
-
-
65649142017
-
A new equation to estimate glomerular filtration rate
-
Levey AS, Stevens LA, Schmid CH, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150:604-612.
-
(2009)
Ann Intern Med
, vol.150
, pp. 604-612
-
-
Levey, A.S.1
Stevens, L.A.2
Schmid, C.H.3
-
10
-
-
79952741730
-
Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome
-
Reitman ZJ, Jin G, Karoly ED, et al. Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome. Proc Natl Acad Sci USA. 2011;108:3270-3275.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 3270-3275
-
-
Reitman, Z.J.1
Jin, G.2
Karoly, E.D.3
-
11
-
-
0035478854
-
Random forests
-
Breiman L. Random forests. Machine Learning. 2001;45:5-32.
-
(2001)
Machine Learning
, vol.45
, pp. 5-32
-
-
Breiman, L.1
-
12
-
-
0242490780
-
Cytoscape: A software environment for integrated models of biomolecular interaction networks
-
Shannon P, Markiel A, Ozier O, et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res. 2003;13:2498-2504.
-
(2003)
Genome Res
, vol.13
, pp. 2498-2504
-
-
Shannon, P.1
Markiel, A.2
Ozier, O.3
-
13
-
-
84906224684
-
Urine and plasma metabolites predict the development of diabetic nephropathy in individuals with type 2 diabetes mellitus
-
Pena MJ, Lambers Heerspink HJ, Hellemons ME, et al. Urine and plasma metabolites predict the development of diabetic nephropathy in individuals with type 2 diabetes mellitus. Diabet Med. 2014; 31:1138-1147.
-
(2014)
Diabet Med
, vol.31
, pp. 1138-1147
-
-
Pena, M.J.1
Lambers Heerspink, H.J.2
Hellemons, M.E.3
-
14
-
-
84887108045
-
Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease
-
Sharma K, Karl B, Mathew AV, et al. Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease. J Am Soc Nephrol. 2013;24:1901-1912.
-
(2013)
J Am Soc Nephrol
, vol.24
, pp. 1901-1912
-
-
Sharma, K.1
Karl, B.2
Mathew, A.V.3
-
15
-
-
84870947792
-
Metabolic profiling reveals new serum biomarkers for differentiating diabetic nephropathy
-
Hirayama A, Nakashima E, Sugimoto M, et al. Metabolic profiling reveals new serum biomarkers for differentiating diabetic nephropathy. Anal Bioanal Chem. 2012;404:3101-3109.
-
(2012)
Anal Bioanal Chem
, vol.404
, pp. 3101-3109
-
-
Hirayama, A.1
Nakashima, E.2
Sugimoto, M.3
-
16
-
-
84899913633
-
Uremic solutes and risk of end-stage renal disease in type 2 diabetes: Metabolomic study
-
Niewczas MA, Sirich TL, Mathew AV, et al. Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study. Kidney Int. 2014;85:1214-1224.
-
(2014)
Kidney Int
, vol.85
, pp. 1214-1224
-
-
Niewczas, M.A.1
Sirich, T.L.2
Mathew, A.V.3
-
17
-
-
80053922229
-
Albuminuria and estimated glomerular filtration rate as predictors of diabetic end-stage renal disease and death
-
Berhane AM, Weil EJ, Knowler WC, Nelson RG, Hanson RL. Albuminuria and estimated glomerular filtration rate as predictors of diabetic end-stage renal disease and death. Clin J Am Soc Nephrol. 2011;6:2444-2451.
-
(2011)
Clin J Am Soc Nephrol
, vol.6
, pp. 2444-2451
-
-
Berhane, A.M.1
Weil, E.J.2
Knowler, W.C.3
Nelson, R.G.4
Hanson, R.L.5
-
18
-
-
84875152321
-
The synergistic relationship between estimated GFR and microalbuminuria in predicting long-term progression to ESRD or death in patients with diabetes: Results from the Kidney Early Evaluation Program (KEEP)
-
Amin AP, Whaley-Connell AT, Li S, et al. The synergistic relationship between estimated GFR and microalbuminuria in predicting long-term progression to ESRD or death in patients with diabetes: results from the Kidney Early Evaluation Program (KEEP). Am J Kidney Dis. 2013;61(4 suppl 2):S12-S23.
-
(2013)
Am J Kidney Dis
, vol.61
, Issue.4
, pp. S12-S23
-
-
Amin, A.P.1
Whaley-Connell, A.T.2
Li, S.3
-
19
-
-
0026605276
-
Pseudouridine excretion in healthy subjects and its accumulation in renal failure
-
Dzúrik R, Lajdová I, Spustová V, Opatrný K Jr. Pseudouridine excretion in healthy subjects and its accumulation in renal failure. Nephron. 1992;61:64-67.
-
(1992)
Nephron
, vol.61
, pp. 64-67
-
-
Dzúrik, R.1
Lajdová, I.2
Spustová, V.3
Opatrný, K.4
-
20
-
-
80655132169
-
ClusterMaker: A multialgorithm clustering plugin for Cytoscape
-
Morris JH, Apeltsin L, Newman AM, et al. ClusterMaker: a multialgorithm clustering plugin for Cytoscape. BMC Bioinformatics. 2011;12:436.
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 436
-
-
Morris, J.H.1
Apeltsin, L.2
Newman, A.M.3
-
21
-
-
84882248502
-
Aberrant Notch1-dependent effects on glomerular parietal epithelial cells promotes collapsing focal segmental glomerulosclerosis with progressive podocyte loss
-
Ueno T, Kobayashi N, Nakayama M, et al. Aberrant Notch1-dependent effects on glomerular parietal epithelial cells promotes collapsing focal segmental glomerulosclerosis with progressive podocyte loss. Kidney Int. 2013;83:1065-1075.
-
(2013)
Kidney Int
, vol.83
, pp. 1065-1075
-
-
Ueno, T.1
Kobayashi, N.2
Nakayama, M.3
-
22
-
-
84879393432
-
Angiotensin II contributes to diabetic renal dysfunction in rodents and humans via Notch1/Snail pathway
-
Gagliardini E, Perico N, Rizzo P, et al. Angiotensin II contributes to diabetic renal dysfunction in rodents and humans via Notch1/Snail pathway. Am J Pathol. 2013;183:119-130.
-
(2013)
Am J Pathol
, vol.183
, pp. 119-130
-
-
Gagliardini, E.1
Perico, N.2
Rizzo, P.3
-
23
-
-
84900549190
-
Renal tubular Notch signaling triggers a prosenescent state after acute kidney injury
-
Sörensen-Zender I, Rong S, Susnik N, et al. Renal tubular Notch signaling triggers a prosenescent state after acute kidney injury. AmJ Physiol Renal Physiol. 2014;306:F907-F915.
-
(2014)
AmJ Physiol Renal Physiol
, vol.306
, pp. F907-F915
-
-
Sörensen-Zender, I.1
Rong, S.2
Susnik, N.3
-
24
-
-
0035865836
-
Tryptophan glycoconjugate as a novel marker of renal function
-
Takahira R, Yonemura K, Yonekawa O, et al. Tryptophan glycoconjugate as a novel marker of renal function. Am J Med. 2001; 110:192-197.
-
(2001)
Am J Med
, vol.110
, pp. 192-197
-
-
Takahira, R.1
Yonemura, K.2
Yonekawa, O.3
-
25
-
-
1642463463
-
The diagnostic value of serum concentrations of 2-(-mannopyranosyl)-L-tryptophan for normal renal function
-
Yonemura K, Takahira R, Yonekawa O, Wada N, Hishida A. The diagnostic value of serum concentrations of 2-(-mannopyranosyl)-L-tryptophan for normal renal function. Kidney Int. 2004;65:1395-1399.
-
(2004)
Kidney Int
, vol.65
, pp. 1395-1399
-
-
Yonemura, K.1
Takahira, R.2
Yonekawa, O.3
Wada, N.4
Hishida, A.5
-
26
-
-
0033826593
-
Mechanism of increases in L-kynurenine and quinolinic acid in renal insufficiency
-
Saito K, Fujigaki S, Heyes MP, et al. Mechanism of increases in L-kynurenine and quinolinic acid in renal insufficiency. Am J Physiol Renal Physiol. 2000;279:F565-F572.
-
(2000)
Am J Physiol Renal Physiol
, vol.279
, pp. F565-F572
-
-
Saito, K.1
Fujigaki, S.2
Heyes, M.P.3
-
27
-
-
0035527466
-
Accumulation of toxic products degradation of kynurenine in hemodialyzed patients
-
Pawlak D, Pawlak K, Malyszko J, Mysliwiec M, Buczko W. Accumulation of toxic products degradation of kynurenine in hemodialyzed patients. Int Urol Nephrol. 2001;33:399-404.
-
(2001)
Int Urol Nephrol
, vol.33
, pp. 399-404
-
-
Pawlak, D.1
Pawlak, K.2
Malyszko, J.3
Mysliwiec, M.4
Buczko, W.5
-
28
-
-
84897868717
-
The aryl hydrocarbon receptor-activating effect of uremic toxins from tryptophan metabolism: A new concept to understand cardiovascular complications of chronic kidney disease
-
Sallée M, Dou L, Cerini C, Poitevin S, Brunet P, Burtey S. The aryl hydrocarbon receptor-activating effect of uremic toxins from tryptophan metabolism: a new concept to understand cardiovascular complications of chronic kidney disease. Toxins (Basel). 2014;6: 934-949.
-
(2014)
Toxins (Basel)
, vol.6
, pp. 934-949
-
-
Sallée, M.1
Dou, L.2
Cerini, C.3
Poitevin, S.4
Brunet, P.5
Burtey, S.6
-
29
-
-
84896719312
-
Proteomic analysis of post-nuclear supernatant fraction and percollpurified membranes prepared from brain cortex of rats exposed to increasing doses of morphine
-
Ujcikova H, Eckhardt A, Kagan D, Roubalova L, Svoboda P. Proteomic analysis of post-nuclear supernatant fraction and percollpurified membranes prepared from brain cortex of rats exposed to increasing doses of morphine. Proteome Sci. 2014;12:11.
-
(2014)
Proteome Sci
, vol.12
, pp. 11
-
-
Ujcikova, H.1
Eckhardt, A.2
Kagan, D.3
Roubalova, L.4
Svoboda, P.5
-
30
-
-
41349110662
-
Mechanisms of disease: The hypoxic tubular hypothesis of diabetic nephropathy
-
Singh DK, Winocour P, Farrington K. Mechanisms of disease: the hypoxic tubular hypothesis of diabetic nephropathy. Nat Clin Pract Nephrol. 2008;4:216-226.
-
(2008)
Nat Clin Pract Nephrol
, vol.4
, pp. 216-226
-
-
Singh, D.K.1
Winocour, P.2
Farrington, K.3
-
31
-
-
84897845228
-
Rap1 ameliorates renal tubular injury in diabetic nephropathy
-
Xiao L, Zhu X, Yang S, et al. Rap1 ameliorates renal tubular injury in diabetic nephropathy. Diabetes. 2014;63:1366-1380.
-
(2014)
Diabetes
, vol.63
, pp. 1366-1380
-
-
Xiao, L.1
Zhu, X.2
Yang, S.3
-
32
-
-
57149107838
-
Rap1b GTPase ameliorates glucoseinduced mitochondrial dysfunction
-
Sun L, Xie P, Wada J, et al. Rap1b GTPase ameliorates glucoseinduced mitochondrial dysfunction. J Am Soc Nephrol. 2008;19: 2293-2301.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 2293-2301
-
-
Sun, L.1
Xie, P.2
Wada, J.3
-
33
-
-
84863023552
-
Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells
-
Wang W, Wang Y, Long J, et al. Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells. Cell Metab. 2012;15:186-200.
-
(2012)
Cell Metab
, vol.15
, pp. 186-200
-
-
Wang, W.1
Wang, Y.2
Long, J.3
-
34
-
-
69449100055
-
Expression and phosphorylation of the Na-Clcotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1
-
Vallon V, Schroth J, Lang F, Kuhl D, Uchida S. Expression and phosphorylation of the Na-Clcotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1. Am J Physiol Renal Physiol. 2009;297:F704-F712.
-
(2009)
Am J Physiol Renal Physiol
, vol.297
, pp. F704-F712
-
-
Vallon, V.1
Schroth, J.2
Lang, F.3
Kuhl, D.4
Uchida, S.5
-
35
-
-
84910625084
-
UnderstanDing genes identified by genome-wide association studies for type 2 diabetes
-
Dorothy Hodgkin Lecture 2014
-
Rutter GA. Dorothy Hodgkin Lecture 2014. UnderstanDing genes identified by genome-wide association studies for type 2 diabetes. Diabet Med. 2014;31:1480-1487.
-
(2014)
Diabet Med
, vol.31
, pp. 1480-1487
-
-
Rutter, G.A.1
|