The synergistic relationship between estimated GFR and microalbuminuria in predicting long-term progression to ESRD or death in patients with diabetes: Results from the kidney early evaluation program (KEEP)

American Journal of Kidney Diseases

Volumn 61, Issue 4 SUPPL.2, 2013, Pages

  Amin, Amit P ^a   Whaley Connell, Adam T ^b   Li, Suying ^c   Chen, Shu Cheng ^c   McCullough, Peter A ^d   Kosiborod, Mikhail N ^e  

^a WASHINGTON UNIVERSITY   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

^c MINNEAPOLIS MEDICAL RESEARCH FOUNDATION   (United States)

^d PROVIDENCE HOSPITAL   (United States)

^e UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

Albuminuria; chronic kidney disease; diabetes mellitus; end stage renal disease; glomerular filtration rate; mortality; nonalbuminuric chronic kidney disease

Indexed keywords

ALBUMIN; CREATININE;

ADULT; AGED; ALBUMIN BLOOD LEVEL; ARTICLE; COHORT ANALYSIS; CREATININE BLOOD LEVEL; DEATH; DIABETES MELLITUS; DISEASE COURSE; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; HUMAN; INCIDENCE; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; MORTALITY; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PROGNOSIS; SURVIVAL PREDICTION;

AGED; ALBUMINURIA; COHORT STUDIES; CREATININE; DIABETIC NEPHROPATHIES; DISEASE PROGRESSION; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; KAPLAN-MEIER ESTIMATE; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROGRAM DEVELOPMENT; PROPORTIONAL HAZARDS MODELS; RISK ASSESSMENT; RISK FACTORS; UNITED STATES;

EID: 84875152321     PISSN: 02726386     EISSN: 15236838     Source Type: Journal    
DOI: 10.1053/j.ajkd.2013.01.005     Document Type: Article

References (51)

1. J.P. Vora, H.A. Ibrahim, G.L. Bakris Responding to the challenge of diabetic nephropathy: the historic evolution of detection, prevention and management J Hum Hypertens 14 10-11 2000 667 685
2. S. Dronavalli, I. Duka, G.L. Bakris The pathogenesis of diabetic nephropathy Nat Clin Pract Endocrinol Metab 4 8 2008 444 452
3. G. Soldatos, M.E. Cooper Diabetic nephropathy: important pathophysiologic mechanisms Diabetes Res Clin Pract 82 suppl 1 2008 S75 S79
4. G. Penno, A. Solini, E. Bonora Clinical significance of nonalbuminuric renal impairment in type 2 diabetes J Hypertens 29 9 2011 1802 1809
5. R.J. Macisaac, C. Tsalamandris, S. Panagiotopoulos, T.J. Smith, K.J. McNeil, G. Jerums Nonalbuminuric renal insufficiency in type 2 diabetes Diabetes Care 27 1 2004 195 200 (Pubitemid 38196732)
6. R.J. Macisaac, S. Panagiotopoulos, K.J. McNeil Is nonalbuminuric renal insufficiency in type 2 diabetes related to an increase in intrarenal vascular disease? Diabetes Care 29 7 2006 1560 1566 (Pubitemid 44127581)
7. H.J. Kramer, Q.D. Nguyen, G. Curhan, C.Y. Hsu Renal insufficiency in the absence of albuminuria and retinopathy among adults with type 2 diabetes mellitus JAMA 289 24 2003 3273 3277 (Pubitemid 37430080)
8. M.C. Thomas, R.J. Macisaac, G. Jerums Nonalbuminuric renal impairment in type 2 diabetic patients and in the general population (National Evaluation of the Frequency of Renal Impairment Co-existing With NIDDM [NEFRON] 11) Diabetes Care 32 8 2009 1497 1502
9. C.A. Johnson, A.S. Levey, J. Coresh, A. Levin, J. Lau, G. Eknoyan Clinical practice guidelines for chronic kidney disease in adults: part II Glomerular filtration rate, proteinuria, and other markers Am Fam Physician 70 6 2004 1091 1097 (Pubitemid 39274343)
10. A.S. Levey, K.U. Eckardt, Y. Tsukamoto Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO) Kidney Int 67 6 2005 2089 2100 (Pubitemid 41623371)
11. A.S. Levey, J. Coresh, E. Balk National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification Ann Intern Med 139 2 2003 137 147
12. A.M. Berhane, E.J. Weil, W.C. Knowler, R.G. Nelson, R.L. Hanson Albuminuria and estimated glomerular filtration rate as predictors of diabetic end-stage renal disease and death Clin J Am Soc Nephrol 6 10 2011 2444 2451
13. V. Rigalleau, C. Lasseur, C. Raffaitin Normoalbuminuric renal-insufficient diabetic patients: a lower-risk group Diabetes Care 30 8 2007 2034 2039 (Pubitemid 47219416)
14. S.E. Ohmit, J.M. Flack, R.M. Peters, W.W. Brown, R. Grimm Longitudinal study of the National Kidney Foundation's (NKF) Kidney Early Evaluation Program (KEEP) J Am Soc Nephrol 14 7 suppl 2 2003 S117 S121
15. W.W. Brown, R.M. Peters, S.E. Ohmit Early detection of kidney disease in community settings: the Kidney Early Evaluation Program (KEEP) Am J Kidney Dis 42 1 2003 22 35 (Pubitemid 36807651)
16. P.A. McCullough, S. Steigerwalt, K. Tolia Cardiovascular disease in chronic kidney disease: data from the Kidney Early Evaluation Program (KEEP) Curr Diabetes Rep 11 1 2011 47 55
17. P.A. McCullough, A. Whaley-Connell, W.W. Brown Cardiovascular risk modification in participants with coronary disease screened by the Kidney Early Evaluation Program Intern Med J 40 12 2010 833 841
18. A. Whaley-Connell, A.S. Bomback, S.I. McFarlane Diabetic cardiovascular disease predicts chronic kidney disease awareness in the Kidney Early Evaluation Program Cardiorenal Med 1 1 2011 45 52
19. E. von Elm, D.G. Altman, M. Egger, S.J. Pocock, P.C. Gotzsche, J.P. Vandenbroucke The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies Ann Intern Med 147 8 2007 573 577 (Pubitemid 351664504)
20. A.S. Levey, L.A. Stevens, C.H. Schmid A new equation to estimate glomerular filtration rate Ann Intern Med 150 9 2009 604 612
21. L.A. Stevens, S. Li, T.M. Kurella Comparison of the CKD Epidemiology Collaboration (CKD-EPI) and Modification of Diet in Renal Disease (MDRD) Study equations: risk factors for and complications of CKD and mortality in the Kidney Early Evaluation Program (KEEP) Am J Kidney Dis 57 3 suppl 2 2011 S9 S16
22. W.S. Cleveland Robust locally weighted regression and smoothing scatterplots J Am Stat Assoc 74 368 1979 829 836
23. B.C. Astor, S.I. Hallan, E.R. Miller III, E. Yeung, J. Coresh Glomerular filtration rate, albuminuria, and risk of cardiovascular and all-cause mortality in the US population Am J Epidemiol 167 10 2008 1226 1234 (Pubitemid 351670638)
24. K. Matsushita, M. van der Velde, B.C. Astor Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis Lancet 375 9731 2010 2073 2081
25. B.C. Astor, K. Matsushita, R.T. Gansevoort Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease A collaborative meta-analysis of kidney disease population cohorts Kidney Int 79 12 2011 1331 1340
26. P. Fioretto, M. Mauer, E. Brocco Patterns of renal injury in NIDDM patients with microalbuminuria Diabetologia 39 12 1996 1569 1576 (Pubitemid 26397369)
27. P. Gaede, P. Vedel, H.H. Parving, O. Pedersen Elevated levels of plasma von Willebrand factor and the risk of macro- and microvascular disease in type 2 diabetic patients with microalbuminuria Nephrol Dial Transplant 16 10 2001 2028 2033 (Pubitemid 32970565)
28. U.M. Vischer, J.J. Emeis, H.J. Bilo von Willebrand factor (vWf) as a plasma marker of endothelial activation in diabetes: improved reliability with parallel determination of the vWf propeptide (vWf:AgII) Thromb Haemost 80 6 1998 1002 1007 (Pubitemid 28556706)
29. T. Hirano, K. Ookubo, K. Kashiwazaki, H. Tajima, G. Yoshino, M. Adachi Vascular endothelial markers, von Willebrand factor and thrombomodulin index, are specifically elevated in type 2 diabetic patients with nephropathy: comparison of primary renal disease Clin Chim Acta 299 1-2 2000 65 75 (Pubitemid 30438790)
30. A. Upadhyay, M.G. Larson, C.Y. Guo Inflammation, kidney function and albuminuria in the Framingham Offspring cohort Nephrol Dial Transplant 26 3 2011 920 926
31. A.K. Bello, B. Hemmelgarn, A. Lloyd Associations among estimated glomerular filtration rate, proteinuria, and adverse cardiovascular outcomes Clin J Am Soc Nephrol 6 6 2011 1418 1426
32. M. Tonelli, S.W. Klarenbach, A.M. Lloyd Higher estimated glomerular filtration rates may be associated with increased risk of adverse outcomes, especially with concomitant proteinuria Kidney Int 80 12 2011 1306 1314
33. R.T. Gansevoort, F.L. Nauta, S.J. Bakker Albuminuria: all you need to predict outcomes in chronic kidney disease? Curr Opin Nephrol Hypertens 19 6 2010 513 518
34. D.E. Weiner, S. Tabatabai, H. Tighiouart Cardiovascular outcomes and all-cause mortality: exploring the interaction between CKD and cardiovascular disease Am J Kidney Dis 48 3 2006 392 401 (Pubitemid 44247251)
35. J. Arnlov, J.C. Evans, J.B. Meigs Low-grade albuminuria and incidence of cardiovascular disease events in nonhypertensive and nondiabetic individuals: the Framingham Heart Study Circulation 112 7 2005 969 975 (Pubitemid 41170264)
36. S.D. Solomon, J. Lin, C.G. Solomon Influence of albuminuria on cardiovascular risk in patients with stable coronary artery disease Circulation 116 23 2007 2687 2693 (Pubitemid 350301148)
37. A.M. Berhane, E.J. Weil, W.C. Knowler, R.G. Nelson, R.L. Hanson Albuminuria and estimated glomerular filtration rate as predictors of diabetic end-stage renal disease and death Clin J Am Soc Nephrol 6 10 2011 2444 2451
38. M.C. Foster, S.J. Hwang, M.G. Larson Cross-classification of microalbuminuria and reduced glomerular filtration rate: associations between cardiovascular disease risk factors and clinical outcomes Arch Intern Med 167 13 2007 1386 1392 (Pubitemid 47052437)
39. G. Cerasola, G. Mule, S. Cottone, E. Nardi, P. Cusimano Hypertension, microalbuminuria and renal dysfunction: the Renal Dysfunction in Hypertension (REDHY) Study J Nephrol 21 3 2008 368 373
40. R. Bouchi, T. Babazono, N. Yoshida Association of albuminuria and reduced estimated glomerular filtration rate with incident stroke and coronary artery disease in patients with type 2 diabetes Hypertens Res 33 12 2010 1298 1304
41. I. Ford, V. Bezlyak, D.J. Stott Reduced glomerular filtration rate and its association with clinical outcome in older patients at risk of vascular events: secondary analysis PLoS Med 6 1 2009 e16
42. M. van der Velde, K. Matsushita, J. Coresh Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality A collaborative meta-analysis of high-risk population cohorts Kidney Int 79 12 2011 1341 1352
43. H. Afghahi, J. Cederholm, B. Eliasson Risk factors for the development of albuminuria and renal impairment in type 2 diabetes - the Swedish National Diabetes Register (NDR) Nephrol Dial Transplant 26 4 2011 1236 1243
44. C.A. Peralta, F. Lin, M.G. Shlipak Race differences in prevalence of chronic kidney disease among young adults using creatinine-based glomerular filtration rate-estimating equations Nephrol Dial Transplant 25 12 2010 3934 3939
45. S.I. McFarlane, P.A. McCullough, J.R. Sowers Comparison of the CKD Epidemiology Collaboration (CKD-EPI) and Modification of Diet in Renal Disease (MDRD) Study equations: prevalence of and risk factors for diabetes mellitus in CKD in the Kidney Early Evaluation Program (KEEP) Am J Kidney Dis 57 3 suppl 2 2011 S24 S31
46. G. Pugliese, A. Solini, E. Bonora The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation provides a better definition of cardiovascular burden associated with CKD than the Modification of Diet in Renal Disease (MDRD) Study formula in subjects with type 2 diabetes Atherosclerosis 218 1 2011 194 199
47. L.A. Stevens, S. Li, T.M. Kurella Comparison of the CKD Epidemiology Collaboration (CKD-EPI) and Modification of Diet in Renal Disease (MDRD) Study equations: risk factors for and complications of CKD and mortality in the Kidney Early Evaluation Program (KEEP) Am J Kidney Dis 57 3)(suppl 2 2011 S9 S16
48. K. Matsushita, B.K. Mahmoodi, M. Woodward Comparison of risk prediction using the CKD-EPI equation and the MDRD Study equation for estimated glomerular filtration rate JAMA 307 18 2012 1941 1951
49. D.J. Newman, M.B. Mattock, A.B. Dawnay Systematic review on urine albumin testing for early detection of diabetic complications Health Technol Assess 9 30 2005 iii-163
50. G.F. Watts, N.A. Taub, J. Mazurkiewicz, K.M. Shaw An examination of the covariability of subclinical albuminuria in insulin-dependent diabetes mellitus: implications for monitoring microalbuminuria Diabetes Res Clin Pract 21 2-3 1993 177 185 (Pubitemid 23344264)
51. G.F. Watts, C. Kubal, S. Chinn Long-term variation of urinary albumin excretion in insulin-dependent diabetes mellitus: some practical recommendations for monitoring microalbuminuria Diabetes Res Clin Pract 9 2 1990 169 177 (Pubitemid 20185883)