No evidence that frailty modifies the positive impact of antihypertensive treatment in very elderly people: An investigation of the impact of frailty upon treatment effect in the HYpertension in the Very Elderly Trial (HYVET) study, a double-blind, placebo-controlled study of antihypertensives in people with hypertension aged 80 and over

BMC Medicine

Volumn 13, Issue 1, 2015, Pages

  Warwick, Jane ^a   Falaschetti, Emanuela ^b   Rockwood, Kenneth ^c   Mitnitski, Arnold ^d   Thijs, Lutgarde ^e   Beckett, Nigel ^f   Bulpitt, Christopher ^f   Peters, Ruth ^b  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c DALHOUSIE UNIVERSITY   (Canada)

^d DALHOUSIE UNIVERSITY   (Canada)

^e UNIVERSITY OF LEUVEN   (Belgium)

^f IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Ageing; Antihypertensives; Frailty; Hypertension

Indexed keywords

INDAPAMIDE; PERINDOPRIL; PLACEBO; ANTIHYPERTENSIVE AGENT;

AGED; ANTIHYPERTENSIVE THERAPY; ARTICLE; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; CONTROLLED CLINICAL TRIAL (TOPIC); CONTROLLED STUDY; FEMALE; FOLLOW UP; FRAIL ELDERLY; FRAILTY INDEX; GERIATRIC ASSESSMENT; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MENTAL HEALTH; MORTALITY; QUALITY OF LIFE; RISK ASSESSMENT; THERAPY EFFECT; TREATMENT OUTCOME; VERY ELDERLY; BLOOD PRESSURE; COMORBIDITY; DOUBLE BLIND PROCEDURE; DRUG COMBINATION; DRUG EFFECTS; INCIDENCE; RANDOMIZED CONTROLLED TRIAL; STROKE;

AGED, 80 AND OVER; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; COMORBIDITY; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FEMALE; FRAIL ELDERLY; HUMANS; HYPERTENSION; INCIDENCE; INDAPAMIDE; MALE; PERINDOPRIL; QUALITY OF LIFE; STROKE;

EID: 84928041055     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/s12916-015-0328-1     Document Type: Article

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