Diminished effort on a progressive ratio task in both unipolar and bipolar depression

Journal of Affective Disorders

Volumn 196, Issue , 2016, Pages 97-100

  Hershenberg, Rachel ^a,b   Satterthwaite, Theodore D ^b   Daldal, Aylin ^b   Katchmar, Natalie ^b   Moore, Tyler M ^b   Kable, Joseph W ^b   Wolf, Daniel H ^b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Anhedonia; Depression; Effort; Motivation; Progressive ratio; Reward

Indexed keywords

ADOLESCENT; ADULT; ANHEDONIA; BIPOLAR DISORDER; CASE CONTROL STUDY; FEMALE; HUMAN; MAJOR DEPRESSION; MALE; MIDDLE AGED; MOTIVATION; PSYCHOLOGY; REWARD; YOUNG ADULT;

ADOLESCENT; ADULT; ANHEDONIA; BIPOLAR DISORDER; CASE-CONTROL STUDIES; DEPRESSIVE DISORDER, MAJOR; FEMALE; HUMANS; MALE; MIDDLE AGED; MOTIVATION; REWARD; YOUNG ADULT;

EID: 84959343035     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2016.02.003     Document Type: Article

References (33)

1. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR 2000 American Psychiatric Publishing Arlington, VA
2. J. Audrain-McGovern, E.P. Wileyto, R. Ashare, J. Cuevas, and A.A. Strasser Reward and affective regulation in depression-prone smokers Biol. Psychiatry 76 2014 689 697
3. A.T. Beck, and R.A. Steer Manual for the Beck Depression Inventory 1993 Psychological Corporation San Antonio, TX
4. D.J. Bond, G. Hadjipavlou, R.W. Lam, R.S. McIntyre, S. Beaulieu, A. Schaffer, and M. Weiss The Canadian network for mood and anxiety treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid attention-deficit/hyperactivity disorder Ann. Clin. Psychiatry 24 2012 23 37
5. J.R. Calabrese, M. Fava, G. Garibaldi, H. Grunze, A.D. Krystal, T. Laughren, W. Macfadden, R. Marin, A.A. Nierenberg, and M. Tohen Methodological approaches and magnitude of the clinical unmet need associated with amotivation in mood disorders J. Affect. Disord. 168 2014 439 451
6. H.W. Chase, R. Nusslock, J.R. Almeida, E.E. Forbes, E.J. LaBarbara, and M.L. Phillips Dissociable patterns of abnormal frontal cortical activation during anticipation of an uncertain reward or loss in bipolar versus major depression Bipolar Disord. 15 2013 839 854
7. A. Der-Avakian, and A. Markou The neurobiology of anhedonia and other reward-related deficits Trends Neurosci. 35 2012 68 77
8. G.S. Dichter Anhedonia in unipolar major depressive disorder: a review Open Psychiatry J. 4 2010 1 9
9. G. Foussias, I. Siddiqui, G. Fervaha, O. Agid, and G. Remington Dissecting negative symptoms in schizophrenia: opportunities for translation into new treatments J. Psychopharmacol. 29 2015 116 126
10. J.F. Goldberg, K.E. Burdick, and C.J. Endick Preliminary randomized, double-blind, placebo-controlled trial of pramipexole added to mood stabilizers for treatment-resistant bipolar depression Am. J. Psychiatry 161 2004 564 566
11. C. Hägele, F. Schlagenhauf, M. Rapp, P. Sterzer, A. Beck, F. Bermpohl, M. Stoy, A. Ströhle, H.-U. Wittchen, and R.J. Dolan Dimensional psychiatry: reward dysfunction and depressive mood across psychiatric disorders Psychopharmacology 232 2015 331 341
12. W. Hodos Progressive ratio as a measure of reward strength Science 134 1961 943 944
13. J.R. Hughes, C.N. Pleasants, and R.W. Pickens Measurement of reinforcement in depression: a pilot study J. Behav. Ther. Exp. Psychiatry 16 1985 231 236
14. I. Pacchiarotti, D.J. Bond, R.J. Baldessarini, W.A. Nolen, H. Grunze, R.W. Licht, R.M. Post, M. Berk, G.M. Goodwin, and G.S. Sachs The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders Am. J. Psychiatry 11 2013 1249 1262
15. D.A. Pizzagalli, E. Goetz, M. Ostacher, D.V. Iosifescu, and R.H. Perlis Euthymic patients with bipolar disorder show decreased reward learning in a probabilistic reward task Biol. Psychiatry 64 2008 162 168
16. D.A. Pizzagalli, D. Iosifescu, L.A. Hallett, K.G. Ratner, and M. Fava Reduced hedonic capacity in major depressive disorder: evidence from a probabilistic reward task J. Psychiatr. Res. 43 2008 76 87
17. R.M. Post The impact of bipolar depression J. Clin. Psychiatry 66 2004 5 10
18. L.C. Quilty, L. Mackew, and R.M. Bagby Distinct profiles of behavioral inhibition and activation system sensitivity in unipolar vs. bipolar mood disorders Psychiatry Res. 219 2014 228 231
19. J.D. Salamone, M. Correa, A. Farrar, and S.M. Mingote Effort-related functions of nucleus accumbens dopamine and associated forebrain circuits Psychopharmacology 191 2007 461 482
20. J.D. Salamone, M.S. Cousins, L.D. McCullough, D.L. Carriero, and R.J. Berkowitz Nucleus accumbens dopamine release increases during instrumental lever pressing for food but not free food consumption Pharmacol. Biochem. Behav. 49 1994 25 31
21. T.D. Satterthwaite, J.W. Kable, L. Vandekar, N. Katchmar, D.S. Bassett, C.F. Baldassano, K. Ruparel, M.A. Elliott, Y.I. Sheline, and R.C. Gur Common and dissociable dysfunction of the reward system in bipolar and unipolar depression Neuropsychopharmacology 40 2015 2258 2268
22. S. Scheggi, T. Pelliccia, A. Ferrari, M.G. De Montis, and C. Gambarana Impramine, fluoxetine and clozapine differently affected reactivity to positive and negative stimuli in a model of motivational anhedonia in rats Neuroscience 291 2015 189 202
23. R.L. Spitzer, J.B.W. Williams, M. Gibbon, and M. First Structured Clinical Interview for DSM-IV (SCID-IV) 1995 Biometrics Research, New York State Psychiatric Institute New York
24. M.T. Treadway, N.A. Bossaller, R.C. Shelton, and D.H. Zald Effort-based decision-making in major depressive disorder: a translational model of motivational anhedonia J. Abnorm. Psychol. 121 2012 553 558
25. M.T. Treadway, J.W. Buckholtz, A.N. Schwartzman, W.E. Lambert, and D.H. Zald Worth the 'EEfRT'? The effort expenditure for rewards task as an objective measure of motivation and anhedonia PLoS One 4 2009 e6598
26. M.T. Treadway, and D.H. Zald Reconsidering anhedonia in depression: lessons from translational neuroscience Neurosci. Biobehav. Rev. 35 2011 537 555
27. M.T. Treadway, and D.H. Zald Parsing anhedonia: translational models of reward-processing deficits in psychopathology Curr. Dir. Psychol. Sci. 22 2013 244 249
28. A.E. Whitton, M.T. Treadway, and D.A. Pizzagalli Reward processing dysfunction in major depression, bipolar disorder and schizophrenia Curr. Opin. Psychiatry 28 2015 7 12
29. P. Willner, D. Benton, E. Brown, S. Cheeta, G. Davies, J. Morgan, and M. Morgan "Depression" increases "craving" for sweet rewards in animal and human models of depression and craving Psychopharmacology 136 1998 272 283
30. P. Willner, M. Field, K. Pitts, and G. Reeve Mood, cue and gender influences on motivation, craving and liking for alcohol in recreational drinkers Behav. Pharmacol. 9 1998 631 642
31. D.H. Wolf, T.D. Satterthwaite, J.J. Kantrowitz, N. Katchmar, L. Vandekar, M.A. Elliott, and K. Ruparel Amotivation in schizophrenia: integrated assessment with behavioral, clinical, and imaging measures Schizophr. Bull. 40 2014 1328 1337
32. X.-h Yang, J. Huang, C.-y Zhu, Y.-f Wang, E.F. Cheung, R.C. Chan, and G.-r Xie Motivational deficits in effort-based decision making in individuals with subsyndromal depression, first-episode and remitted depression patients Psychiatry Res. 220 2014 874 882
33. L.N. Yatham, J.M. Goldstein, E. Vieta, C.L. Bowden, H. Grunze, R.M. Post, T. Suppes, and J.R. Calabrese Atypical antipsychotics in bipolar depression: potential mechanisms of action J. Clin. Psychiatry 66 2005 40 48