메뉴 건너뛰기




Volumn 67, Issue 4, 2016, Pages 417-419

Genetic Causality in Complex Traits the Case of Uric Acid

Author keywords

association studies; causality; genetics; Mendelian randomization; single nucleotide variants; uric acid

Indexed keywords

URIC ACID;

EID: 84959319372     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2015.09.109     Document Type: Editorial
Times cited : (5)

References (16)
  • 1
    • 84872042939 scopus 로고    scopus 로고
    • Use of Mendelian randomisation to assess potential benefit of clinical intervention
    • S. Burgess, A. Butterworth, A. Malarstig, and S.G. Thompson Use of Mendelian randomisation to assess potential benefit of clinical intervention Br Med J 345 2012 e7325
    • (2012) Br Med J , vol.345 , pp. e7325
    • Burgess, S.1    Butterworth, A.2    Malarstig, A.3    Thompson, S.G.4
  • 2
    • 84897112970 scopus 로고    scopus 로고
    • Causality in genetics: The gradient of genetic effects and back to Koch's postulates of causality
    • A.J. Marian Causality in genetics: the gradient of genetic effects and back to Koch's postulates of causality Circ Res 114 2014 e18 e21
    • (2014) Circ Res , vol.114 , pp. e18-e21
    • Marian, A.J.1
  • 3
    • 84899476119 scopus 로고    scopus 로고
    • Guidelines for investigating causality of sequence variants in human disease
    • D.G. MacArthur, T.A. Manolio, D.P. Dimmock, and et al. Guidelines for investigating causality of sequence variants in human disease Nature 508 2014 469 476
    • (2014) Nature , vol.508 , pp. 469-476
    • MacArthur, D.G.1    Manolio, T.A.2    Dimmock, D.P.3
  • 4
    • 79957506175 scopus 로고    scopus 로고
    • Strategic approaches to unraveling genetic causes of cardiovascular diseases
    • A.J. Marian, and J. Belmont Strategic approaches to unraveling genetic causes of cardiovascular diseases Circ Res 108 2011 1252 1269
    • (2011) Circ Res , vol.108 , pp. 1252-1269
    • Marian, A.J.1    Belmont, J.2
  • 5
    • 42249087308 scopus 로고    scopus 로고
    • The complete genome of an individual by massively parallel DNA sequencing
    • D.A. Wheeler, M. Srinivasan, M. Egholm, and et al. The complete genome of an individual by massively parallel DNA sequencing Nature 452 2008 872 876
    • (2008) Nature , vol.452 , pp. 872-876
    • Wheeler, D.A.1    Srinivasan, M.2    Egholm, M.3
  • 6
    • 35648976118 scopus 로고    scopus 로고
    • The diploid genome sequence of an individual human
    • S. Levy, G. Sutton, P.C. Ng, and et al. The diploid genome sequence of an individual human PLoS Biol 5 2007 e254
    • (2007) PLoS Biol , vol.5 , pp. e254
    • Levy, S.1    Sutton, G.2    Ng, P.C.3
  • 7
    • 77449112270 scopus 로고    scopus 로고
    • Nature's genetic gradients and the clinical phenotype
    • A.J. Marian Nature's genetic gradients and the clinical phenotype Circ Cardiovasc Genet 2 2009 537 539
    • (2009) Circ Cardiovasc Genet , vol.2 , pp. 537-539
    • Marian, A.J.1
  • 8
    • 54949100735 scopus 로고    scopus 로고
    • Uric acid and cardiovascular risk
    • D.I. Feig, D.H. Kang, and R.J. Johnson Uric acid and cardiovascular risk N Engl J Med 359 2008 1811 1821
    • (2008) N Engl J Med , vol.359 , pp. 1811-1821
    • Feig, D.I.1    Kang, D.H.2    Johnson, R.J.3
  • 9
    • 84959420157 scopus 로고    scopus 로고
    • Causal assessment of serum urate levels in cardiometabolic diseases: Through a Mendelian Randomization study
    • T. Keenan, W. Zhao, A. Rasheed, and et al. Causal assessment of serum urate levels in cardiometabolic diseases: through a Mendelian Randomization study J Am Coll Cardiol 67 2016 407 416
    • (2016) J Am Coll Cardiol , vol.67 , pp. 407-416
    • Keenan, T.1    Zhao, W.2    Rasheed, A.3
  • 10
    • 47249137081 scopus 로고    scopus 로고
    • 'Mendelian randomization' equals instrumental variable analysis with genetic instruments
    • G.L. Wehby, R.L. Ohsfeldt, and J.C. Murray 'Mendelian randomization' equals instrumental variable analysis with genetic instruments Stat Med 27 2008 2745 2749
    • (2008) Stat Med , vol.27 , pp. 2745-2749
    • Wehby, G.L.1    Ohsfeldt, R.L.2    Murray, J.C.3
  • 11
    • 84855853297 scopus 로고    scopus 로고
    • Molecular genetic studies of complex phenotypes
    • A.J. Marian Molecular genetic studies of complex phenotypes Transl Res 159 2012 64 79
    • (2012) Transl Res , vol.159 , pp. 64-79
    • Marian, A.J.1
  • 12
    • 84881442965 scopus 로고    scopus 로고
    • Association of plasma uric acid with ischaemic heart disease and blood pressure: Mendelian randomisation analysis of two large cohorts
    • T.M. Palmer, B.G. Nordestgaard, M. Benn, and et al. Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts Br Med J 347 2013 f4262
    • (2013) Br Med J , vol.347 , pp. f4262
    • Palmer, T.M.1    Nordestgaard, B.G.2    Benn, M.3
  • 13
    • 84941971658 scopus 로고    scopus 로고
    • Uric acid and cardiovascular events: A Mendelian randomization study
    • M.E. Kleber, G. Delgado, T.B. Grammer, and et al. Uric acid and cardiovascular events: a Mendelian randomization study J Am Soc Nephrol 26 2015 2831 2838
    • (2015) J Am Soc Nephrol , vol.26 , pp. 2831-2838
    • Kleber, M.E.1    Delgado, G.2    Grammer, T.B.3
  • 14
  • 15
    • 84935487980 scopus 로고    scopus 로고
    • Effects of xanthine oxidase inhibition in hyperuricemic heart failure patients: The Xanthine Oxidase Inhibition for Hyperuricemic Heart Failure Patients (EXACT-HF) study
    • M.M. Givertz, K.J. Anstrom, M.M. Redfield, and et al. Effects of xanthine oxidase inhibition in hyperuricemic heart failure patients: the Xanthine Oxidase Inhibition for Hyperuricemic Heart Failure Patients (EXACT-HF) study Circulation 131 2015 1763 1771
    • (2015) Circulation , vol.131 , pp. 1763-1771
    • Givertz, M.M.1    Anstrom, K.J.2    Redfield, M.M.3
  • 16
    • 84878932271 scopus 로고    scopus 로고
    • Uric acid induces oxidative stress and growth inhibition by activating adenosine monophosphate-activated protein kinase and extracellular signal-regulated kinase signal pathways in pancreatic beta cells
    • Y. Zhang, T. Yamamoto, I. Hisatome, and et al. Uric acid induces oxidative stress and growth inhibition by activating adenosine monophosphate-activated protein kinase and extracellular signal-regulated kinase signal pathways in pancreatic beta cells Mol Cell Endocrinol 375 2013 89 96
    • (2013) Mol Cell Endocrinol , vol.375 , pp. 89-96
    • Zhang, Y.1    Yamamoto, T.2    Hisatome, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.