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Volumn 146, Issue 2, 2016, Pages 456S-459S

Pharmacokinetics of S-Allyl-L-cysteine in rats is characterized by high oral absorption and extensive renal reabsorption

Author keywords

Aged garlic extract; Oral absorption; Pharmacokinetics; Renal reabsorption; S allyl L cysteine

Indexed keywords

DRUG METABOLITE; GARLIC EXTRACT; N ACETYL S ALLYLCYSTEINE; N ACETYL S ALLYLCYSTEINE SULFOXIDE; S ALLYLCYSTEINE; SULFUR AMINO ACID; UNCLASSIFIED DRUG; ALLIIN; CYSTEINE; N-ACETYL-S-ALLYLCYSTEINE; PLANT EXTRACT; S-ALLYLCYSTEINE;

EID: 84959294054     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.114.201749     Document Type: Article
Times cited : (22)

References (20)
  • 1
    • 0035126826 scopus 로고    scopus 로고
    • Historical perspective on the use of garlic
    • Rivlin RS. Historical perspective on the use of garlic. J Nutr 2001;131 (Suppl):951S-4S.
    • (2001) J Nutr , vol.131 , pp. 951S-954S
    • Rivlin, R.S.1
  • 2
    • 0029828635 scopus 로고    scopus 로고
    • A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids
    • Steiner M, Khan AH, Holbert D, Lin RI. A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids. Am J Clin Nutr 1996;64:866-70.
    • (1996) Am J Clin Nutr , vol.64 , pp. 866-870
    • Steiner, M.1    Khan, A.H.2    Holbert, D.3    Lin, R.I.4
  • 3
    • 4744340348 scopus 로고    scopus 로고
    • Inhibiting progression of coronary calcification using aged garlic extract in patients receiving statin therapy: a preliminary study
    • BudoffMJ, Takasu J, Flores FR, Niihara Y, Lu B, Lau BH, Rosen RT, Amagase H. Inhibiting progression of coronary calcification using aged garlic extract in patients receiving statin therapy: a preliminary study. Prev Med 2004;39:985-91.
    • (2004) Prev Med , vol.39 , pp. 985-991
    • Budoff, M.J.1    Takasu, J.2    Flores, F.R.3    Niihara, Y.4    Lu, B.5    Lau, B.H.6    Rosen, R.T.7    Amagase, H.8
  • 4
    • 70349295182 scopus 로고    scopus 로고
    • Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: a randomized clinical trial
    • BudoffMJ, Ahmadi N, Gul KM, Liu ST, Flores FR, Tiano J, Takasu J, Miller E, Tsimikas S. Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: a randomized clinical trial. Prev Med 2009;49:101-7.
    • (2009) Prev Med , vol.49 , pp. 101-107
    • Budoff, M.J.1    Ahmadi, N.2    Gul, K.M.3    Liu, S.T.4    Flores, F.R.5    Tiano, J.6    Takasu, J.7    Miller, E.8    Tsimikas, S.9
  • 5
    • 77956649139 scopus 로고    scopus 로고
    • Aged garlic extract lowers blood pressure in patients with treated but uncontrolled hypertension: a randomized controlled trial
    • Ried K, Frank OR, Stocks NP. Aged garlic extract lowers blood pressure in patients with treated but uncontrolled hypertension: a randomized controlled trial. Maturitas 2010;67:144-50.
    • (2010) Maturitas , vol.67 , pp. 144-150
    • Ried, K.1    Frank, O.R.2    Stocks, N.P.3
  • 6
    • 84861339537 scopus 로고    scopus 로고
    • Supplementation with aged garlic extract improves both NK and gd-T cell function and reduces the severity of cold and flu symptoms: a randomized, double-blind, placebo-controlled nutrition intervention
    • Nantz MP, Rowe CA, Muller CE, Creasy RA, Stanilka JM, Percival SS. Supplementation with aged garlic extract improves both NK and gd-T cell function and reduces the severity of cold and flu symptoms: a randomized, double-blind, placebo-controlled nutrition intervention. Clin Nutr 2012;31:337-44.
    • (2012) Clin Nutr , vol.31 , pp. 337-344
    • Nantz, M.P.1    Rowe, C.A.2    Muller, C.E.3    Creasy, R.A.4    Stanilka, J.M.5    Percival, S.S.6
  • 9
    • 33749254924 scopus 로고    scopus 로고
    • Pharmacokinetics and tissue distribution of S-allylcysteine in rats
    • Yan CK, Zeng FD. Pharmacokinetics and tissue distribution of S-allylcysteine in rats. Asian J Drug Metab Pharmacok. 2005;5:61-9.
    • (2005) Asian J Drug Metab Pharmacok , vol.5 , pp. 61-69
    • Yan, C.K.1    Zeng, F.D.2
  • 10
    • 0036786389 scopus 로고    scopus 로고
    • Sulfoxides as urinary metabolites of S-allyl-L-cysteine in rats: evidence for the involvement of flavincontaining monooxygenases
    • Krause RJ, Glocke SC, Elfarra AA. Sulfoxides as urinary metabolites of S-allyl-L-cysteine in rats: evidence for the involvement of flavincontaining monooxygenases. Drug Metab Dispos 2002;30:1137-42.
    • (2002) Drug Metab Dispos , vol.30 , pp. 1137-1142
    • Krause, R.J.1    Glocke, S.C.2    Elfarra, A.A.3
  • 14
    • 0027275566 scopus 로고
    • Physiological parameters in laboratory animals and humans
    • Davies B, Morris T. Physiological parameters in laboratory animals and humans. Pharm Res 1993;10:1093-5.
    • (1993) Pharm Res , vol.10 , pp. 1093-1095
    • Davies, B.1    Morris, T.2
  • 15
    • 0034029294 scopus 로고    scopus 로고
    • Inhibition of cholesterol biosynthesis by organosulfur compounds derived from garlic
    • Liu L, Yeh YY. Inhibition of cholesterol biosynthesis by organosulfur compounds derived from garlic. Lipids 2000;35:197-203.
    • (2000) Lipids , vol.35 , pp. 197-203
    • Liu, L.1    Yeh, Y.Y.2
  • 16
    • 28844505085 scopus 로고    scopus 로고
    • Protective effect of S-allyl cysteine and S-propyl cysteine on acetaminophen-induced hepatotoxicity in mice
    • Hsu CC, Lin CC, Liao TS, Yin MC. Protective effect of S-allyl cysteine and S-propyl cysteine on acetaminophen-induced hepatotoxicity in mice. Food Chem Toxicol 2006;44:393-7.
    • (2006) Food Chem Toxicol , vol.44 , pp. 393-397
    • Hsu, C.C.1    Lin, C.C.2    Liao, T.S.3    Yin, M.C.4
  • 17
    • 0030222364 scopus 로고    scopus 로고
    • Attenuation of rat ischemic brain damage by aged garlic extracts: a possible protecting mechanism as antioxidants
    • Numagami Y, Sato S, Ohnishi ST. Attenuation of rat ischemic brain damage by aged garlic extracts: a possible protecting mechanism as antioxidants. Neurochem Int 1996;29:135-43.
    • (1996) Neurochem Int , vol.29 , pp. 135-143
    • Numagami, Y.1    Sato, S.2    Ohnishi, S.T.3
  • 18
    • 0028313439 scopus 로고
    • Amino acid transport in the small intestine
    • Munck LK, Munck BG. Amino acid transport in the small intestine. Physiol Res 1995;44:335-46.
    • (1995) Physiol Res , vol.44 , pp. 335-346
    • Munck, L.K.1    Munck, B.G.2
  • 19
    • 38349170961 scopus 로고    scopus 로고
    • Amino acid transport across mammalian intestinal and renal epithelia
    • Bröer S. Amino acid transport across mammalian intestinal and renal epithelia. Physiol Rev 2008;88:249-86.
    • (2008) Physiol Rev , vol.88 , pp. 249-286
    • Bröer, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.