All Ribosomes Are Created Equal. Really?

Trends in Biochemical Sciences

Volumn 41, Issue 2, 2016, Pages 121-123

  Preiss, Thomas ^a,b  

^a Australian National University   (Australia)

^b VICTOR CHANG CARDIAC RESEARCH INSTITUTE   (Australia)

Author keywords

Mass spectrometry; Molecular machine; Post transcriptional regulation; Protein synthesis; Ribosome

Indexed keywords

INITIATION FACTOR; MESSENGER RNA; MUTANT PROTEIN; RIBOSOME RNA; RNA BINDING PROTEIN;

BACTERIAL CELL; CATALYSIS; CELL STRUCTURE; DNA TEMPLATE; EMBRYONIC STEM CELL; EUKARYOTE; GENETIC DISORDER; HUMAN; MALIGNANT NEOPLASTIC DISEASE; MALIGNANT TRANSFORMATION; MASS SPECTROMETRY; MOLECULAR BIOLOGY; MONOSOME; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; POLYSOME; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN SYNTHESIS; RIBOSOME; RIBOSOMOPATHY; RNA TRANSLATION; SACCHAROMYCES CEREVISIAE; SHORT SURVEY; STOICHIOMETRY; TISSUE DIFFERENTIATION; ULTRACENTRIFUGATION; X RAY CRYSTALLOGRAPHY; EUKARYOTIC CELL; METABOLISM;

EUKARYOTIC CELLS; PROTEIN BIOSYNTHESIS; RIBOSOMES;

EID: 84959252826     PISSN: 09680004     EISSN: 13624326     Source Type: Journal    
DOI: 10.1016/j.tibs.2015.11.009     Document Type: Short Survey

References (9)

1. Slavov N., et al. Differential Stoichiometry among Core Ribosomal Proteins. Cell Rep. 2015, 13:1-31.
2. Palade G.E. A small particulate component of the cytoplasm. J. Biophys. Biochem. Cytol. 1955, 1:59-68.
3. Ramakrishnan V. The ribosome emerges from a black box. Cell 2014, 159:979-984.
4. Jackson R.J., et al. The mechanism of eukaryotic translation initiation and principles of its regulation. Nat. Rev. Mol. Cell Biol. 2010, 11:113-127.
5. Gebauer F., et al. From cis-regulatory elements to complex RNPs and back. Cold Spring Harb. Perspect. Biol. 2012, 4. a012245.
6. Mauro V.P., Edelman G.M. The ribosome filter hypothesis. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:12031-12036.
7. Shi Z., Barna M. Translating the genome in time and space: specialized ribosomes, RNA regulons, and RNA-binding proteins. Annu. Rev. Cell Dev. Biol. 2015, 31:31-54.
8. Gilbert W.V. Functional specialization of ribosomes?. Trends Biochem. Sci. 2011, 36:127-132.
9. De Keersmaecker K., et al. Ribosomopathies and the paradox of cellular hypo- to hyperproliferation. Blood 2015, 125:1377-1382.