Tumor eosinophil infiltration and improved survival of colorectal cancer patients: Iowa Women's Health Study

Modern Pathology

Volumn 29, Issue 5, 2016, Pages 516-527

  Prizment, Anna E ^a,b   Vierkant, Robert A ^c   Smyrk, Thomas C ^c   Tillmans, Lori S ^c   Lee, James J ^d   Sriramarao, P ^e   Nelson, Heather H ^a,b   Lynch, Charles F ^f   Thibodeau, Stephen N ^c   Church, Timothy R ^a   Cerhan, James R ^c   Anderson, Kristin E ^a,b   Limburg, Paul J ^c  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c MAYO CLINIC   (United States)

^d MAYO GRADUATE SCHOOL   (United States)

^e UNIVERSITY OF MINNESOTA   (United States)

^f UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EOSINOPHIL PEROXIDASE; MOLECULAR MARKER;

ADULT; AGED; ARTICLE; BODY MASS; CANCER LOCALIZATION; CANCER MORTALITY; CANCER PATIENT; CANCER STAGING; CANCER SURVIVAL; CAUSE OF DEATH; CELL INFILTRATION; COLORECTAL CANCER; CYTOTOXIC T LYMPHOCYTE; DEGRANULATION; EOSINOPHIL; EOSINOPHIL COUNT; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; IOWA; LIFESTYLE; MAJOR CLINICAL STUDY; POSTMENOPAUSE; PRIORITY JOURNAL; SMOKING; TISSUE MICROARRAY; TUMOR INFILTRATING EOSINOPHIL; WOMEN'S HEALTH; COLORECTAL TUMOR; IMMUNOLOGY; KAPLAN MEIER METHOD; MIDDLE AGED; MORTALITY; PATHOLOGY; PROPORTIONAL HAZARDS MODEL;

AGED; COLORECTAL NEOPLASMS; EOSINOPHILS; FEMALE; HUMANS; IOWA; KAPLAN-MEIER ESTIMATE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS;

EID: 84959250314     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2016.42     Document Type: Article

References (46)

1. Chaput N, Svrcek M, Aupérin A, et al. Tumourinfiltrating CD68+ and CD57+ cells predict patient outcome in stage II-III colorectal cancer. Br J Cancer 2013; 109: 1013-1022
2. Shunyakov L, Ryan CK, Sahasrabudhe DM, et al. The influence of host response on colorectal cancer prognosis. Clin Colorectal Cancer 2004; 4: 38-45
3. Nosho K, Baba Y, Tanaka N, et al. Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: Cohort study and literature review. J Pathol 2010; 222: 350-366
4. Fridman WH, Pagès F, Sautès-Fridman C, et al. The immune contexture in human tumours: impact on clinical outcome. Nat Rev Cancer 2012; 12: 298-306
5. Tosolini M, Kirilovsky A, Mlecnik B, et al. Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, Th2, Treg, Th17) in patients with colorectal cancer. Cancer Res 2011; 71: 1263-1271
6. Ellyard J, Simson L, Parish C. Th2-mediated antitumour immunity: friend or foe? Tissue Antigens 2007; 70: 1-11
7. Hogan SP, Rosenberg HF, Moqbel R, et al. Eosinophils: Biological properties and role in health and disease. Clin Exp Allergy 2008; 38: 709-750
8. Kita H. Eosinophils: Multifaceted biological properties and roles in health and disease. Immunol Rev 2011; 242: 161-177
9. Lee JJ, Jacobsen EA, McGarry MP, et al. Eosinophils in health and disease: The LIAR hypothesis. Clin Exp Allergy 2010; 40: 563-575
10. Lotfi R, Lee JJ, Lotze MT. Eosinophilic granulocytes and damage-Associated molecular pattern molecules (DAMPs): Role in the inflammatory response within tumors. J Immunother 2007; 30: 16-28
11. Venge R, Byström J, Carlson M, et al. Eosinophil cationic protein (ECP): Molecular and biological properties and the use of ECP as a marker of eosinophil activation in disease. Clin Exp Allergy 1999; 29: 1172-1186
12. Legrand F, Driss V, Delbeke M, et al. Human eosinophils exert TNF-α and granzyme A-mediated tumoricidal activity toward colon carcinoma cells. J Immunol 2010; 185: 7443-7451
13. Carretero R, Sektioglu IM, Garbi N, et al. Eosinophils orchestrate cancer rejection by normalizing tumor vessels and enhancing infiltration of CD8 T cells. Nat Immunol 2015; 16: 609-617
14. Gatault S, Legrand F, Delbeke M, et al. Involvement of eosinophils in the anti-Tumor response. Cancer Immunol Immunother 2012; 61: 1527-1534
15. Davis BP, Rothenberg ME. Eosinophils and cancer. Cancer Immunol Res 2014; 2: 1-8
16. Van Driel WJ, Kievit-Tyson P, van den Broek LC, et al. Presence of an eosinophilic infiltrate in cervical squamous carcinoma results from a type 2 immune response. Gynecol Oncol 1999; 74: 188-195
17. Pinto A, Aldinucci D, Gloghini A, et al. The role of eosinophils in the pathobiology of Hodgkin's disease. Ann Oncol 1997; 8(Suppl 2): 89-96
18. Iwasaki K, Torisu M, Fujimura T. Malignant tumor and eosinophils. I. prognostic significance in gastric cancer. Cancer 1986; 58: 1321-1327
19. Ishibashi S, Ohashi Y, Suzuki T, et al. Tumor-Associated tissue eosinophilia in human esophageal squamous cell carcinoma. Anticancer Res 2006; 26: 1419-1424
20. Martinelli-Kly CP, Mendis BR, Lombardi T. Eosinophils and oral squamous cell carcinoma: a short review. J Oncol 2009; 2009: 310132
21. Moezzi J, Gopalswamy N, Haas RJ, et al. Stromal eosinophilia in colonic epithelial neoplasms. Am J Gastroenterol 2000; 95: 520-523
22. Nagtegaal I, Marijnen C, Kranenbarg EK, et al. Local and distant recurrences in rectal cancer patients are predicted by the nonspecific immune response; specific immune response has only a systemic effect-A histopathological and immunohistochemical study. BMC Cancer 2001; 1: 7
23. Kiziltaş S, Ramadan SS, Topuzoǧlu, et al. Does the severity of tissue eosinophilia of colonic neoplasms reflect their malignancy potential? Turk J Gastroenterol 2008; 19: 239-244
24. Fernandez-Aceero MJ, Galindo-Gallego M, Sanz J, et al. Prognostic influence of tumor-Associated eosinophilic infiltrate in colorectal carcinoma. Cancer 2000; 88: 1544-1548
25. Nielsen HJ, Hansen U, Christensen IJ, et al. Independent prognostic value of eosinophil and mast cell infiltration in colorectal cancer tissue. J Pathol 1999; 189: 487-495
26. Pretlow TP, Keith EF, Cryar AK, et al. Eosinophil infiltration of human colonic carcinomas as a prognostic indicator. Cancer Res 1983; 43: 2997-3000
27. Fisher ER, Paik S, Rockette H, et al. Prognostic significance of eosinophils and mast cells in rectal cancer: Findings from the national surgical adjuvant breast and bowel project (protocol R-01). Hum Pathol 1989; 20: 159-163
28. Harbaum L, Pollheimer MJ, Kornprat P, et al. Peritumoral eosinophils predict recurrence in colorectal cancer. Mod Pathol 2015; 28: 403-413
29. Willetts L, Parker K, Wesselius L, et al. Immunodetection of occult eosinophils in lung tissue biopsies may help predict survival in acute lung injury. Respir Res 2011; 12: 116
30. Protheroe C, Woodruff SA, de Petris G, et al. A novel histologic scoring system to evaluate mucosal biopsies from patients with eosinophilic esophagitis. Clin Gastroenterol Hepatol 2009; 7: 749-755.e11
31. Nunez-Nateras R, Castle EP, Protheroe CA, et al. Predicting response to bacillus Calmette-Guérin (BCG) in patients with carcinoma in situ of the bladder. Urol Oncol 2014; 32: 45.e23-45.e30
32. Zhang S, Folsom AR, Sellers TA, et al. Better breast cancer survival for postmenopausal women who are less overweight and eat less fat. The Iowa Women's Health Study. Cancer 1995; 76: 275-283
33. Folsom AR, Kushi LH, Anderson KE, et al. Associations of general and abdominal obesity with multiple health outcomes in older women: the Iowa Women's Health Study. Arch Intern Med 2000; 160: 2117-2128
34. Lee JE, Baba Y, Ng K, et al. Statin use and colorectal cancer risk according to molecular subtypes in two large prospective cohort studies. Cancer Prev Res 2011; 4: 1808-1815
35. Schernhammer ES, Giovannucci E, Baba Y, et al. B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP). PLoS One 2011; 6: e21102
36. Graham RP, Vierkant RA, Tillmans LS, et al. Tumor budding in colorectal carcinoma: Confirmation of prognostic significance and histologic cutoff in a population-based cohort. Am J Surg Pathol 2015; 39: 1340-1346
37. Limsui D, Vierkant RA, Tillmans LS, et al. Cigarette smoking and colorectal cancer risk by molecularly defined subtypes. J Natl Cancer Inst 2010; 102: 1012-1022
38. Woodruff SA, Masterson JC, Fillon S, et al. Role of eosinophils in inflammatory bowel and gastrointestinal diseases. J Pediatr Gastroenterol Nutr 2011; 52: 650-661
39. Tepper RI, Coffman RL, Leder P. An eosinophildependent mechanism for the antitumor effect of interleukin-4. Science 1992; 257: 548-551
40. Costain DJ, Guha AK, Liwski RS, et al. Murine hypodense eosinophils induce tumour cell apoptosis by a granzyme B-dependent mechanism. Cancer Immunol Immunother 2001; 50: 293-299
41. Simson L, Ellyard JI, Dent LA, et al. Regulation of carcinogenesis by IL-5 and CCL11: a potential role for eosinophils in tumor immune surveillance. J Immunol 2007; 178: 4222-4229
42. Mattes J, HulettM, XieWet al. Immunotherapy of cytotoxic T cell-resistant tumors by T helper 2 cells: an eotaxin and STAT6-dependent process. J Exp Med 2003; 197: 387-393
43. Clarke CA, Smith MA, Laniyan I, et al. Eosinophil MBP extract modulates oncogene expression in prostate tumor cells: a preliminary study with monolayer cultures. J Cancer Ther 2015; 6: 482-492
44. Sosman JA, Bartemes K, Offord KP, et al. Evidence for eosinophil activation in cancer patients receiving recombinant interleukin-4: Effects of interleukin-4 alone and following interleukin-2 administration. Clin Cancer Res 1995; 1: 805-812
45. Huland E, Huland H. Tumor-Associated eosinophilia in interleukin-2-Treated patients: evidence of toxic eosinophil degranulation on bladder cancer cells. J Cancer Res Clin Oncol 1992; 118: 463-467
46. Cormier S, Taranova A, Bedient C, et al. Pivotal advance: eosinophil infiltration of solid tumors is an early and persistent inflammatory host response. J Leukoc Biol 2006; 79: 1131-1139