Association of HLA-G 3' untranslated region variants with type 1 diabetes mellitus

Human Immunology

Volumn 77, Issue 4, 2016, Pages 358-364

  de Albuquerque, Rafael S ^a,b   Mendes Junior, Celso Teixeira ^a   Lucena Silva, Norma ^c   da Silva, Camila Leal Lopes ^a   Rassi, Diane Meire ^a   Veiga Castelli, Luciana C ^a   Foss Freitas, Maria Cristina ^a   Foss, Milton César ^a   Deghaide, Neifi Hassan Saloum ^a   Moreau, Philippe ^d   Gregori, Silvia ^b   Castelli, Erick C ^e   Donadi, Eduardo Antônio ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

^d DIF   (France)

^e SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

3' untranslated region; Brazilians; Gene regulation; HLA G; Type 1 diabetes mellitus

Indexed keywords

HLA G ANTIGEN; 3' UNTRANSLATED REGION;

3' UNTRANSLATED REGION; ADOLESCENT; ADULT; ANTIGEN EXPRESSION; ARTICLE; BRAZILIAN; CHILD; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RNA PROCESSING; ALLELE; CASE CONTROL STUDY; GENETIC VARIATION; GENETICS; GENOTYPE; MIDDLE AGED; ODDS RATIO; SINGLE NUCLEOTIDE POLYMORPHISM; YOUNG ADULT;

3' UNTRANSLATED REGIONS; ADOLESCENT; ADULT; ALLELES; CASE-CONTROL STUDIES; CHILD; DIABETES MELLITUS, TYPE 1; FEMALE; GENE FREQUENCY; GENETIC VARIATION; GENOTYPE; HLA-G ANTIGENS; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

EID: 84959228474     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2016.02.001     Document Type: Article

References (38)

1. Klein J., Sato A. The HLA system. First of two parts. N. Engl. J. Med. 2000, 343:702-709.
2. Klein J., Sato A. The HLA system. First of two parts. N. Engl. J. Med. 2000, 343:782-786.
3. Kanga U., Vaidyanathan B., Jaini R., Menon P.S., Mehra N.K. HLA haplotypes associated with type 1 diabetes mellitus in North Indian children. Hum. Immunol. 2004, 65:47-53.
4. Gorodezky C., Alaez C., Murguía A., Rodríguez A., Balladares S., et al. HLA and autoimmune diseases: Type 1 diabetes (T1D) as an example. Autoimmun. Rev. 2006, 5:187-194.
5. Eike M.C., Becker T., Humphreys K., Olsson M., Lie B.A. Conditional analyses on the T1DGC MHC dataset: novel associations with type 1 diabetes around HLA-G and confirmation of HLA-B. Genes Immun. 2009, 10:56-67.
6. Solini A.1, Muscelli E., Stignani M., Melchiorri L., Santini E., Rossi C., Astiarraga B.D., Rizzo R., Baricordi O.R. Soluble human leukocyte antigen-g expression and glucose tolerance in subjects with different degrees of adiposity. J. Clin. Endocrinol. Metab. 2010, 95:3342-3346.
7. Carosella E.D., Moreau P., Le Maoult J., Le Discorde M., Dausset J., Rouas-Freiss HLA-G molecules: from maternal-fetal tolerance to tissue acceptance. Adv. Immunol. 2003, 81:199-252.
8. Carosella E.D., Favier B., Rouas-Freiss N., Moreau P., Lemaoult J. Beyond the increasing complexity of the immunomodulatory HLA-G molecule. Blood 2008, 111:4862-4870.
9. Sullivan L.C., Hoare H.L., McCluskey J., Rossjohn J., Brooks A.G. A structural perspective on MHC class Ib molecules in adaptive immunity. Trends Immnunol 2006, 27:413-420.
10. King A., Hiby S.E., Gardner L., Joseph S., Bowen J.M., Verma S., et al. Recognition of trophoblasts HLA class I molecules by decidual NK cell receptors-a review. Placenta 2006, 21:81-85.
11. Cirulli V., Zalatan J., MCmaster M., Prinsen R., Salomon D.R., et al. The class I HLA repertoire of pancreatic islets comprises the nonclassical class Ib antigen HLA-G. Diabetes 2006, 55:1214-1222.
12. Shiroishi M., Tsumoto K., Amano K., Shirakihara Y., Colonna M., et al. Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:8856-8861.
13. Wastowski I.J., Sampaio-Barros P.D., Amstalden E.M., Palomino G.M., Marques-Neto J.F., et al. HLA-G expression in the skin of patients with systemic sclerosis. J. Rheumatol. 2009, 36:1230-1234.
14. Boyson J.E., Erskine R., Whitman M.C., Chiu M., Lau J.M., et al. Disulfide bond-mediated dimerization of HLA-G on the cell surface. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:16180-16185.
15. Donadi E.A., Castelli E.C., Arnaiz-Villena A., Roger M., Rey D., Moreau P. Implications of the polymorphism of HLA-G on its function, regulation, evolution and disease association. Cell. Mol. Life Sci. 2011, 68:369-395.
16. Ober C., Billstrand C., Kuldanek S., Tan Z. The miscarriage associated HLA-G -725G allele influences transcription rates in JEG-3 cells. Hum. Reprod. 2006, 21:1743-1748.
17. Castelli E.C., Mendes-Junior C.T., Veiga-Castelli L.C., Roger M., et al. A comprehensive study of polymorphic sites along the HLA-G gene: implication for gene regulation and evolution. Mol. Biol. Evol. 2011, 28:3069-3086.
18. Rousseau P., Le Discorde M., Mouillot G., Marcou C., Carosella E.D., Moreau P. The 14 bp deletion-insertion polymorphism in the 3' UT region of the HLA-G gene influences HLA-G mRNA stability. Hum. Immunol. 2003, 64:1005-1010.
19. Castelli E.C., Mendes-Junior C.T., Deghaide N.H., de Albuquerque R.S., Muniz Y.C., et al. The genetic structure of 3'untranslated region of the HLA-G gene: polymorphisms and haplotypes. Genes Immun. 2010, 11:134-141.
20. Martelli-Palomino G., Pancotto J.A., Muniz Y.C., Mendes-Junior C.T., Castelli E.C., et al. Polymorphic sites at the 3' untranslated region of the HLA-G gene are associated with differential hla-g soluble levels in the Brazilian and French population. PLoS ONE 2013, 8:e71742.
21. Tan Z., Randall G., Fan J., Camoretti-Mercado B., Brockman-Schneider R., Pan L., et al. Allele-specific targeting of microRNAs to HLA-G and risk of asthma. Am. J. Hum. Genet. 2007, 81:829-834.
22. Yie S.M., Li L.H., Xiao R., Librach C.L. A single base-pair mutation in the 3'-untranslated region of HLA-G mRNA is associated with pre-eclampsia. Mol. Hum. Reprod. 2008, 14:649-653.
23. Castelli E.C., Moreau P., Oya e Chiromatzo A., Mendes-Junior C.T., Veiga-Castelli L.C., et al. In silico analysis of microRNAS targeting the HLA-G 3' untranslated region alleles and haplotypes. Hum. Immunol. 2009, 70:1020-1025.
24. Miller S.A., Dykes D.D. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988, 16:1215.
25. Excoffier L., Slatkin M. Incorporating genotypes of relatives into a test of linkage disequilibrium. Am. J. Hum. Genet. 1998, 62:171-180.
26. Excoffier L., Lischer H. Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol. Ecol. Resour. 2010, 10:564-567.
27. Rousset F. GENEPOP'007: a complete re-implementation of the GENEPOP software for Windows and Linux. Mol. Ecol. Resour. 2008, 8:103-106.
28. Guo S.W., Thompson E.A. Performing the exact test of Hardy-Weinberg proportion for multiple alleles. Biometrics 1992, 48:361-372.
29. Excoffier L., Slatkin M. Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol. Biol. Evol. 1995, 12:921-927.
30. Stephens M., Smith N.J., Donnelly P. New statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet. 2001, 68:978-989.
31. Qin Z.S., Niu T., Liu J.S. Partition-ligation-expectation-maximization algorithm for haplotype inference with single-nucleotide polymorphisms. Am. J. Hum. Genet. 2002, 71:1242-1247.
32. Sabbagh A., Luisi P., Castelli E.C., Gineau L., Courtin D., et al. Worldwide genetic variation at the 3' untranslated region of the HLA-G gene: balancing selection influencing genetic diversity. Genes Immun. 2014, 15:95-106.
33. Svejgaard A., Jakobsen B.K., Platz P., Ryder L.P., Nerup J., et al. HLA associations in insulin-dependent diabetes: search for heterogeneity in different groups of patients from a homogeneous population. Tissue Antigens 1986, 28:237-244.
34. Alvarez M., Piedade J., Balseiro S., Ribas G., Regateiro F. HLA-G 3'-UTR SNP and 14-bp deletion polymorphisms in Portuguese and Guinea-Bissau populations. Int. J. Immunogenet. 2009, 36:361-366.
35. Lucena-Silva N., Monteiro A.R., de Albuquerque R.S., Gomes R.G., Mendes-Junior C.T., et al. Haplotype frequencies based on eight polymorphic sites at the 3' untranslated region of the HLA-G gene in individuals from two different geographical regions of Brazil. Tissue Antigens 2012, 79:272-278.
36. Fernandes A.P., Louzada-Junior P., Foss M.C., DonadI E.A. HLA-DRB1, DQB1, and DQA1 allele profile in Brazilian patients with type 1 diabetes mellitus. Ann. N. Y. Acad. Sci. 2002, 958:305-308.
37. Van Der Werf N., Kroese F.G., Rozing J., Hillebrands J.L. Viral infections as potential triggers of type 1 diabetes. Diabetes Metab. Res. Rev. 2007, 23:169-183.
38. Grommé M., Neefjes J. Antigen degradation or presentation by MHC class I molecules via classical and non-classical pathways. Mol. Immunol. 2002, 39:181-202.