Post-H1N1 flu vaccination narcolepsy in Switzerland: A retrospective survey in the 30 sleep-certified Swiss centers

European Neurology

Volumn 75, Issue 3-4, 2016, Pages 105-108

  Kallweit, Ulf ^a   Mathis, Johannes ^a   Jenni, Oskar G ^b   Heinzer, Raphaël ^d   Haba Rubio, José ^d   Baumann, Christian R ^c   Cervena, Katerina ^e   Bassetti, Claudio L A ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^e GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Certified sleep centers; Hypocretin; Narcolepsy; Post H1N1 narcolepsy; Vaccination

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CATAPLEXY; CHILD; CLINICAL ARTICLE; FEMALE; HEALTH SURVEY; HUMAN; INFLUENZA A (H1N1); INFLUENZA VACCINATION; MALE; NARCOLEPSY; NIGHT SLEEP; POLYSOMNOGRAPHY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SOMNOLENCE; SWITZERLAND; ADVERSE EFFECTS; INCIDENCE; INFLUENZA A VIRUS (H1N1); QUESTIONNAIRE; VACCINATION;

INFLUENZA VACCINE;

ADULT; CATAPLEXY; CHILD; HUMANS; INCIDENCE; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA VACCINES; NARCOLEPSY; RETROSPECTIVE STUDIES; SURVEYS AND QUESTIONNAIRES; SWITZERLAND; VACCINATION;

EID: 84959204762     PISSN: 00143022     EISSN: 14219913     Source Type: Journal    
DOI: 10.1159/000444318     Document Type: Article

References (21)

1. Ohayon MM, Priest RG, Zulley J, Smirne S, Paiva T. Prevalence of narcolepsy symptomatology and diagnosis in the European general population. Neurology 2002; 58: 1826-1833.
2. Dauvilliers Y, Arnulf I, Mignot E. Narcolepsy with cataplexy. Lancet 2007; 369: 499-511.
3. Aran A, Lin L, Nevsimalova S, et al. Elevated anti-streptococcal antibodies in patients with recent narcolepsy onset. Sleep 2009; 32: 979-983.
4. Nohynek H, Jokinen J, Partinen M, et al. AS03 adjuvanted AH1N1 vaccine associated with an abrupt increase in the incidence of childhood narcolepsy in Finland. PLoS One 2012; 7:e33536.
5. Wijnans L, Lecomte C, de Vries C, et al. The incidence of narcolepsy in Europe: before, during, and after the influenza A(H1N1) pdm09 pandemic and vaccination campaigns. Vaccine 2013; 31: 1246-1254.
6. Fontana A, Gast H, Reith W, Recher M, Birchler T, Bassetti CL. Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss?. Brain 2010; 133: 1300-1311.
7. Montplaisir J, Petit D, Quinn MJ, Ouakki M, Deceuninck G, Desautels A, Mignot E, De Wals P. Risk of narcolepsy associated with inactivated adjuvanted (AS03) A/H1N1 (2009) pandemic influenza vaccine in Quebec. PLoS One 2014; 9:e108489.
8. Winstone AM, Stellitano L, Verity C, Andrews N, Miller E, Stowe J, Shneerson J. Clinical features of narcolepsy in children vaccinated with AS03 adjuvanted pandemic A/ H1N1 2009 influenza vaccine in England. Dev Med Child Neurol 2013; 56: 1117-1123.
9. Dauvilliers Y, Montplaisir J, Cochen V, et al. Post-H1N1 narcolepsy-cataplexy. Sleep 2010; 33: 1428-1430.
10. Partinen M, Kornum BR, Plazzi G, Jennum P, Julkunen I, Vaarala O. Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination. Lancet Neurol 2014; 13: 600-613.
11. Han F, Lin L, Warby SC, et al. Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in China. Ann Neurol 2011; 70: 410-417.
12. Vaarala O, Vuorela A, Partinen M, et al. Antigenic differences between AS03 adjuvanted influenza A (H1N1) pandemic vaccines: implications for pandemrix-Associated narcolepsy risk. PLoS One 2014; 9:e114361.
13. Haba-Rubio J, Rossetti AO, Tafti M, Heinzer R: [Narcolepsy with cataplexy associated with H1N1 vaccination]. Rev Neurol (Paris) 2011; 167: 563-566.
14. Mathis J, Strozzi S. Narkolepsie, eine Folge der H1N1-Grippeimpfung?. Schweiz Med Forum 2012; 12: 8-10.
15. Swissmedic: Abschlussbericht Analyse der Datenbank PaniFlow über vermutete unerwünschte Wirkungen nach Impfungen gegen die pandemische Grippe (H1N1) 2009 in der Schweiz. Swissmedic, 2010.
16. American Academy of Sleep Medicine: International Classification of Sleep Disorders, ed 3. Darien, American Academy of Sleep Medicine, 2014.
17. Dauvilliers Y, Arnulf I, Lecendreux M, et al. Increased risk of narcolepsy in children and adults after pandemic H1N1 vaccination in France. Brain 2013; 136: 2486-2496.
18. Oberle D, Drechsel-Bäuerle U, Schmidtmann I, Mayer G, Keller-Stanislawski B. Incidence of narcolepsy in Germany. Sleep 2015; 38: 1619-1628.
19. Partinen M, Saarenpää-Heikkilä O, Ilveskoski I, et al. Increased incidence and clinical picture of childhood narcolepsy following the 2009 H1N1 pandemic vaccination campaign in Finland. PLoS One 2012; 7:e33723.
20. Pizza F, Peltola H, Sarkanen T, Moghadam KK, Plazzi G, Partinen M. Childhood narcolepsy with cataplexy: comparison between post-H1N1 vaccination and sporadic cases. Sleep Med 2014; 15: 262-265.
21. Pizza F, Franceschini C, Peltola H, et al. Clinical and polysomnographic course of childhood narcolepsy with cataplexy. Brain 2013; 136: 3787-3795.