Heat shock protein 27 plays a pivotal role in myofibroblast differentiation and in the development of bleomycin-induced pulmonary fibrosis

PLoS ONE

Volumn 11, Issue 2, 2016, Pages

  Park, Ah Mee ^a   Kanai, Kyosuke ^a   Itoh, Tatsuki ^a   Sato, Takao ^a   Tsukui, Tatsuya ^b   Inagaki, Yutaka ^c   Selman, Moises ^d   Matsushima, Kouji ^b   Yoshie, Osamu ^a  

^a KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BLEOMYCIN; COLLAGEN TYPE 1; FIBRONECTIN; HEAT SHOCK PROTEIN 27; OSTEOPONTIN; PEPTIDES AND PROTEINS; PROSURFACTANT PROTEIN C; PROTEIN F4 80; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UVOMORULIN; ACTA2 PROTEIN, HUMAN; ACTIN;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; FIBROSING ALVEOLITIS; GENE SILENCING; HSP27 GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG FIBROBLAST; MALE; MOUSE; MYOFIBROBLAST; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; UPREGULATION; ANIMAL; CELL LINE; CHEMICALLY INDUCED; DRUG EFFECTS; FIBROBLAST; LUNG FIBROSIS; PATHOPHYSIOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION;

ACTINS; AGED; ANIMALS; BLEOMYCIN; CELL DIFFERENTIATION; CELL LINE; COLLAGEN TYPE I; FEMALE; FIBROBLASTS; FIBRONECTINS; GENE KNOCKDOWN TECHNIQUES; HSP27 HEAT-SHOCK PROTEINS; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; MALE; MICE; MYOFIBROBLASTS; OSTEOPONTIN; POLYMERASE CHAIN REACTION; PULMONARY FIBROSIS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84959199481     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0148998     Document Type: Article

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