Evidence of a Direct Effect of Myocardial Steatosis on LV Hypertrophy and Diastolic Dysfunction in Adult and Adolescent Obesity

JACC: Cardiovascular Imaging

Volumn 8, Issue 12, 2015, Pages 1468-1470

  Banerjee, Rajarshi ^b   Rial, Belen ^b   Holloway, Cameron J ^b   Lewandowski, Adam J ^b   Robson, Matthew D ^b   Osuchukwu, Chinwe ^b   Schneider, Jurgen E ^b   Leeson, Paul ^b   Rider, Oliver J ^a   Neubauer, Stefan ^b  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

TRIACYLGLYCEROL;

ADOLESCENT OBESITY; BODY MASS; DIASTOLIC DYSFUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HUMAN; LETTER; MYOCARDIAL DISEASE; MYOCARDIAL STEATOSIS; PRIORITY JOURNAL; SEX DIFFERENCE; SLEEP DISORDERED BREATHING; TRIACYLGLYCEROL BLOOD LEVEL; ADIPOSE TISSUE; ADOLESCENT; ADULT; AGE; CARDIAC MUSCLE; CHILD; COHORT ANALYSIS; COMPARATIVE STUDY; DIASTOLE; FEMALE; HYPERTROPHY, LEFT VENTRICULAR; MALE; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OBESITY; PEDIATRIC OBESITY; PHYSIOLOGY; PROCEDURES; PROGNOSIS; PROSPECTIVE STUDY; RISK ASSESSMENT;

ADIPOSE TISSUE; ADOLESCENT; ADULT; AGE FACTORS; BODY MASS INDEX; CHILD; COHORT STUDIES; DIASTOLE; FEMALE; HUMANS; HYPERTROPHY, LEFT VENTRICULAR; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MYOCARDIUM; OBESITY; PEDIATRIC OBESITY; PROGNOSIS; PROSPECTIVE STUDIES; RISK ASSESSMENT; SEX FACTORS;

EID: 84959193065     PISSN: 1936878X     EISSN: 18767591     Source Type: Journal    
DOI: 10.1016/j.jcmg.2014.12.019     Document Type: Letter

References (5)

1. K. Nyman, M. Graner, M.O. Pentikainen, and et al. Cardiac steatosis and left ventricular function in men with metabolic syndrome J Cardiovasc Magn Reson 15 2013 103
2. R.W. van der Meer, S. Hammer, J.W. Smit, and et al. Short-term caloric restriction induces accumulation of myocardial triglycerides and decreases left ventricular diastolic function in healthy subjects Diabetes 56 2007 2849 2853
3. L.S. Szczepaniak, R.L. Dobbins, G.J. Metzger, and et al. Myocardial triglycerides and systolic function in humans: in vivo evaluation by localized proton spectroscopy and cardiac imaging Magn Reson Med 49 2003 417 423
4. O.J. Rider, J.M. Francis, D. Tyler, and et al. Effects of weight loss on myocardial energetics and diastolic function in obesity Int J Cardiovasc Imaging 29 2013 1043 1050
5. B. Rial, M.D. Robson, S. Neubauer, and J.E. Schneider Rapid quantification of myocardial lipid content in humans using single breath-hold 1H MRS at 3 Tesla Magn Reson Med 66 2011 619 624