Quantitative and Comparative Contents of Nitrate and Nitrite in Beta vulgaris L. by Reversed-Phase High-Performance Liquid Chromatography-Fluorescence

Food Analytical Methods

Volumn 9, Issue 4, 2016, Pages 1002-1008

  dos Santos Baião, Diego ^a   Conte Junior, Carlos Adam ^b   Paschoalin, Vânia Margaret Flosi ^a   Alvares, Thiago Silveira ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

Author keywords

Beetroot; Food composition; High performance liquid chromatography; Nitrate; Nitrite

Indexed keywords

CHROMATOGRAPHY; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUIDS; NITRATES; NITRIC OXIDE;

BEETROOT; BLOOD PERFUSION; ENDOTHELIAL FUNCTION; FLUORESCENCE DETECTION; FOOD COMPOSITIONS; NITRATE CONTENTS; NITRITE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

LIQUID CHROMATOGRAPHY;

EID: 84959168674     PISSN: 19369751     EISSN: 1936976X     Source Type: Journal    
DOI: 10.1007/s12161-015-0275-7     Document Type: Article

References (28)

1. 2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans. J Appl Physiol 107:1144–1155. doi:10.1152/japplphysiol.00722.2009
2. Cermak NM, Res P, Stinkens R, Lundberg JO, Gibala MJ et al (2012) No improvement in endurance performance after a single dose of beetroot juice. Int J Sport Nutr Exerc Metab 22:470–478, PMD: 23212319
3. Cheng CF, Tsang CW (1998) Simultaneous determination of nitrite, nitrate and ascorbic acid in canned vegetable juices by reverse-phase ion-interaction HPLC. Food Addit Contam 15:753–758. doi:10.1080/02652039809374706
4. Fulford J, Winyard PG, Vanhatalo A, Bailey SJ, Blackwell JR et al (2013) Influence of dietary nitrate supplementation on human skeletal muscle metabolism and force production during maximum voluntary contractions. Pflugers Arch 465:517–528. doi:10.1007/s00424-013-1220-5
5. Gilchrist M, Winyard PG, Aizawa K, Anning C, Shore A et al (2013) Effect of dietary nitrate on blood pressure, endothelial function, and insulin sensitivity in type 2 diabetes. Free Radic Biol Med 60:89–97. doi:10.1016/j.freeradbiomed.2013.01.024
6. Habermeyer M, Roth A, Guth S, Diel P, Engel KH et al (2015) Nitrate and nitrite in the diet: how to assess their benefit and risk for human health. Mol Nutr Food Res 59:106–128. doi:10.1002/mnfr.201400286
7. Hetrick EM, Schoenfisch MH (2009) Analytical chemistry of nitric oxide. Annu Rev Anal Chem 2:409–433. doi:10.1146/annurev-anchem-060908-155146
8. Hobbs DA, Kaffa N, George TW, Methven L, Lovegrove JA (2012) Blood pressure-lowering effects of beetroot juice and novel beetroot-enriched bread products in normotensive male subjects. Br J Nutr 108:2066–2074. doi:10.1017/S0007114512000190
9. Jimidar M, Hartmann C, Cousement N, Massart DL (1995) Determination of nitrate and nitrite in vegetables by capillary electrophoresis with indirect detection. J Chromatogr A 706:479–492. doi:10.1016/0021-9673(94)01290-U
10. Jobgen WS, Jobgen SC, Li H, Meininger CJ, Wu G (2007) Analysis of nitrite and nitrate in biological samples using high-performance liquid chromatography. J Chromatogr B Anal Technol Biomed Life Sci 851:71–82. doi:10.1016/j.jchromb.2006.07.018
11. Kapil V, Milsom AB, Okorie M, Maleki-Toyserkani S, Akram F et al (2010) Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO. Hypertension 56:274–281. doi:10.1161/HYPERTENSIONAHA.110.153536
12. 2 uptake kinetics, and muscle and cognitive function in older adults. Am J Physiol Regul Integr Comp Physiol 304:R73–R83. doi:10.1152/ajpregu.00406.2012
13. 2 cost of walking and running: a placebo-controlled study. J Appl Physiol 110:591–600. doi:10.1152/japplphysiol.01070.2010
14. Lidder S, Webb AJ (2013) Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate-nitrite-nitric oxide pathway. Br J Clin Pharmacol 75:677–696. doi:10.1111/j.1365-2125.2012.04420.x
15. Murphy M, Eliot K, Heuertz RM, Weiss E (2012) Whole beetroot consumption acutely improves running performance. J Acad Nutr Diet 112:548–552. doi:10.1016/j.jand.2011.12.002
16. Pennington JAT (1998) Dietary exposure models for nitrates and nitrites. Food Control 9:385–395. doi:10.1016/S0956-7135(98)00019-X
17. Pussemier L, Larondelle Y, Van Peteghem C, Huyghebaert A (2006) Chemical safety of conventionally and organically produced foodstuffs: a tentative comparison under Belgian conditions. Food Control 17:14–21. doi:10.1016/j.foodcont.2004.08.003
18. Santamaría P (2006) Nitrate in vegetables: toxicity, content, intake and EC regulation. J Sci Food Agric 86:10–17. doi:10.1002/jsfa.2351
19. Siu DC, Henshall A (1998) Ion chromatographic determination of nitrate and nitrite in meat products. J Chromatogr A 804:157–160. doi:10.1016/S0021-9673(97)01245-4
20. Stokes KY, Dugas TR, Tang Y, Garg H, Guidry E et al (2009) Dietary nitrite prevents hypercholesterolemic microvascular inflammation and reverses endothelial dysfunction. Am J Physiol Heart Circ Physiol 296:H1281–H1288. doi:10.1152/ajpheart.01291.2008
21. Tamme T, Reinik M, Roasto M, Juhkam K, Tenno T et al (2006) Nitrates and nitrites in vegetables and vegetable-based products and their intakes by the Estonian population. Food Addit Contam 23:355–361. doi:10.1080/02652030500482363
22. Tsikas D (2007) Analysis of nitrite and nitrate in biological fluids by assays based on griess reaction: appraisal of the griess reaction in the l-arginine/nitric oxide area of research. J Chromatogr B Anal Technol Biomed Life Sci 851:51–70. doi:10.1016/j.jchromb.2006.07.054
23. Tullio JA, Otto RF, Boer A, Ohse S (2013) Beetroot cropping in natural and protected environments in summer. Rev Bras Eng Agríc Ambient 17:1074–1079. doi:10.1590/S1415-43662013001000008
24. Vanhatalo A, Bailey SJ, Blackwell JR, DiMenna FJ, Pavey TG et al (2010) Acute and chronic effects of dietary nitrate supplementation on blood pressure and the physiological responses to moderate-intensity and incremental exercise. Am J Physiol Regul Integr Comp Physiol 299:1121–1131. doi:10.1152/ajpregu.00206.2010
25. Vanhatalo A, Fulford J, Bailey SJ, Balckwell JR, Winyard PG et al (2011) Dietary nitrate reduces muscle metabolic perturbation and improves exercise tolerance in hypoxia. J Physiol 589:5517–5528. doi:10.1113/jphysiol.2011.216341
26. Watada AE, Ko NP, Minott DA (1996) Factors affecting quality of fresh-cut horticultural produce. Postharvest Biol Technol 9:115–193. doi:10.1016/S0925-5214(96)00041-5
27. Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z et al (2008) Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension 51:784–790. doi:10.1161/hypertensionaha.107.103523
28. Wylie LJ, Kelly J, Bailey SJ, Blackwell JR, Skiba PF et al (2013) Beetroot juice and exercise: pharmacodynamic and dose–response relationships. J Appl Physiol 115:325–336. doi:10.1152/japplphysiol.00372.2013