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Volumn 55, Issue 3, 2016, Pages 313-358

A Qualitative Review on the Pharmacokinetics of Antibiotics in Saliva: Implications on Clinical Pharmacokinetic Monitoring in Humans

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; AMOXICILLIN; AMPICILLIN; ANTIBIOTIC AGENT; AZITHROMYCIN; CEFADROXIL; CEFALEXIN; CEFIXIME; CEFOTIAM; CEFUROXIME; CEPHALOSPORIN DERIVATIVE; CIPROFLOXACIN; CLARITHROMYCIN; CLOXACILLIN; DOXYCYCLINE; ENOXACIN; ERYTHROMYCIN; GENTAMICIN; MACROLIDE; MOXIFLOXACIN; NORFLOXACIN; OFLOXACIN; PEFLOXACIN; PENICILLIN DERIVATIVE; QUINOLONE DERIVATIVE; ROXITHROMYCIN; STREPTOMYCIN; TETRACYCLINE DERIVATIVE; TOBRAMYCIN; UNINDEXED DRUG; ANTIINFECTIVE AGENT;

EID: 84959125561     PISSN: 03125963     EISSN: 11791926     Source Type: Journal    
DOI: 10.1007/s40262-015-0321-z     Document Type: Review
Times cited : (24)

References (85)
  • 1
    • 46649089336 scopus 로고    scopus 로고
    • The preferences of adult outpatients in medical or dental care settings for giving saliva, urine or blood for clinical testing
    • PID: 18519997
    • Koka S, Beebe TJ, Merry SP, et al. The preferences of adult outpatients in medical or dental care settings for giving saliva, urine or blood for clinical testing. J Am Dent Assoc. 2008;139:735–40.
    • (2008) J Am Dent Assoc. , vol.139 , pp. 735-740
    • Koka, S.1    Beebe, T.J.2    Merry, S.P.3
  • 2
    • 84883551516 scopus 로고    scopus 로고
    • Utility of noninvasive biomatrices in pharmacokinetic studies
    • COI: 1:CAS:528:DC%2BC3sXht1CrurnO, PID: 23939915
    • Raju KS, Taneja I, Singh SP, et al. Utility of noninvasive biomatrices in pharmacokinetic studies. Biomed Chromatogr. 2013;27:1354–66.
    • (2013) Biomed Chromatogr. , vol.27 , pp. 1354-1366
    • Raju, K.S.1    Taneja, I.2    Singh, S.P.3
  • 3
    • 59949083369 scopus 로고    scopus 로고
    • Measurement of xenobiotics in saliva: is saliva an attractive alternative matrix? Case studies and analytical perspectives
    • COI: 1:CAS:528:DC%2BD1MXns1agsA%3D%3D, PID: 18816455
    • Mullangi R, Agrawal S, Srinivas NR. Measurement of xenobiotics in saliva: is saliva an attractive alternative matrix? Case studies and analytical perspectives. Biomed Chromatogr. 2009;23:3–25.
    • (2009) Biomed Chromatogr. , vol.23 , pp. 3-25
    • Mullangi, R.1    Agrawal, S.2    Srinivas, N.R.3
  • 4
    • 0026668614 scopus 로고
    • Therapeutic drug monitoring in saliva: an update
    • COI: 1:STN:280:DyaK3s7itFKktA%3D%3D, PID: 1478004
    • Drobitch RK, Svensson CK. Therapeutic drug monitoring in saliva: an update. Clin Pharmacokinet. 1992;23:365–79.
    • (1992) Clin Pharmacokinet. , vol.23 , pp. 365-379
    • Drobitch, R.K.1    Svensson, C.K.2
  • 5
    • 24144501128 scopus 로고    scopus 로고
    • Review: the physiology of saliva and transfer of drugs into saliva
    • COI: 1:CAS:528:DC%2BD2MXltFejs70%3D, PID: 15944052
    • Aps JK, Martens LC. Review: the physiology of saliva and transfer of drugs into saliva. Forensic Sci Int. 2005;150:119–31.
    • (2005) Forensic Sci Int. , vol.150 , pp. 119-131
    • Aps, J.K.1    Martens, L.C.2
  • 6
    • 65349132081 scopus 로고    scopus 로고
    • Mechanism and implication of cephalosporin penetration into oropharyngeal mucosa
    • COI: 1:CAS:528:DC%2BD1MXltVagsbw%3D, PID: 19396515
    • Najjar TA, Alkharfy KM, Saad SY. Mechanism and implication of cephalosporin penetration into oropharyngeal mucosa. J Infect Chemother. 2009;15:70–4.
    • (2009) J Infect Chemother. , vol.15 , pp. 70-74
    • Najjar, T.A.1    Alkharfy, K.M.2    Saad, S.Y.3
  • 7
    • 84872839875 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of antiepileptic drugs by use of saliva
    • COI: 1:CAS:528:DC%2BC3sXhtV2hurw%3D, PID: 23288091
    • Patsalos PN, Berry DJ. Therapeutic drug monitoring of antiepileptic drugs by use of saliva. Ther Drug Monit. 2013;35:4–29.
    • (2013) Ther Drug Monit. , vol.35 , pp. 4-29
    • Patsalos, P.N.1    Berry, D.J.2
  • 8
    • 70449701839 scopus 로고    scopus 로고
    • Oral fluid testing for drugs of abuse
    • COI: 1:CAS:528:DC%2BD1MXhsVSkurbF, PID: 19745062
    • Bosker WM, Huestis MA. Oral fluid testing for drugs of abuse. Clin Chem. 2009;55:1910–31.
    • (2009) Clin Chem. , vol.55 , pp. 1910-1931
    • Bosker, W.M.1    Huestis, M.A.2
  • 9
    • 79952463386 scopus 로고    scopus 로고
    • Bioanalytical issues in patient-friendly sampling methods for therapeutic drug monitoring: focus on antiretroviral drugs
    • PID: 21083054
    • ter Heine R, Bejinen JH, Huitema AD. Bioanalytical issues in patient-friendly sampling methods for therapeutic drug monitoring: focus on antiretroviral drugs. Bioanalysis. 2009;1:1329–38.
    • (2009) Bioanalysis. , vol.1 , pp. 1329-1338
    • ter Heine, R.1    Bejinen, J.H.2    Huitema, A.D.3
  • 10
    • 84904957808 scopus 로고    scopus 로고
    • A comprehensive review on the pharmacokinetics of antibiotics in interstitial fluid spaces in humans: implications on dosing and clinical pharmacokinetic monitoring
    • COI: 1:CAS:528:DC%2BC2cXhtVOis7rF, PID: 24972859
    • Kiang TK, Hafeli UO, Ensom MH. A comprehensive review on the pharmacokinetics of antibiotics in interstitial fluid spaces in humans: implications on dosing and clinical pharmacokinetic monitoring. Clin Pharmacokinet. 2014;53:695–730.
    • (2014) Clin Pharmacokinet. , vol.53 , pp. 695-730
    • Kiang, T.K.1    Hafeli, U.O.2    Ensom, M.H.3
  • 11
    • 84868213774 scopus 로고    scopus 로고
    • Therapeutic drug monitoring in interstitial fluid: a feasibility study using a comprehensive panel of drugs
    • COI: 1:CAS:528:DC%2BC38Xht1yksLzN, PID: 22941939
    • Kiang TK, Schmitt V, Ensom MH, et al. Therapeutic drug monitoring in interstitial fluid: a feasibility study using a comprehensive panel of drugs. J Pharm Sci. 2012;101:4642–52.
    • (2012) J Pharm Sci. , vol.101 , pp. 4642-4652
    • Kiang, T.K.1    Schmitt, V.2    Ensom, M.H.3
  • 12
    • 0031811505 scopus 로고    scopus 로고
    • Clinical relevance of therapeutic drug monitoring of digoxin and gentamicin in the saliva of children
    • COI: 1:CAS:528:DyaK1cXjvVChs7Y%3D, PID: 9631920
    • Berkovitch M, Bistritzer T, Aladjem M, et al. Clinical relevance of therapeutic drug monitoring of digoxin and gentamicin in the saliva of children. Ther Drug Monit. 1998;20:253–6.
    • (1998) Ther Drug Monit. , vol.20 , pp. 253-256
    • Berkovitch, M.1    Bistritzer, T.2    Aladjem, M.3
  • 13
    • 0033840689 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of once daily gentamicin in serum and saliva of children
    • COI: 1:CAS:528:DC%2BD3cXlsVWqs74%3D, PID: 11014472
    • Berkovitch M, Goldman M, Siliverman R, et al. Therapeutic drug monitoring of once daily gentamicin in serum and saliva of children. Eur J Pediatr. 2000;159:697–8.
    • (2000) Eur J Pediatr. , vol.159 , pp. 697-698
    • Berkovitch, M.1    Goldman, M.2    Siliverman, R.3
  • 14
    • 0021848453 scopus 로고
    • Measurement of tobramycin concentrations in saliva
    • COI: 1:STN:280:DyaL2M3jtVSmtA%3D%3D, PID: 4006728
    • Hendeles L, Hill M, Lafrate RP. Measurement of tobramycin concentrations in saliva. Drug Intell Clin Pharm. 1985;19:378–80.
    • (1985) Drug Intell Clin Pharm. , vol.19 , pp. 378-380
    • Hendeles, L.1    Hill, M.2    Lafrate, R.P.3
  • 15
    • 13644255949 scopus 로고    scopus 로고
    • Determination of tobramycin in saliva is not suitable for therapeutic drug monitoring of patients with cystic fibrosis
    • COI: 1:CAS:528:DC%2BD2MXhtVejsLc%3D, PID: 15698943
    • Madsen V, Lind A, Rasmussen M, et al. Determination of tobramycin in saliva is not suitable for therapeutic drug monitoring of patients with cystic fibrosis. J Cyst Fibros. 2004;3:249–51.
    • (2004) J Cyst Fibros. , vol.3 , pp. 249-251
    • Madsen, V.1    Lind, A.2    Rasmussen, M.3
  • 16
    • 0008390642 scopus 로고
    • Studies on excretion of antibiotics in human saliva. I. Penicillin and streptomycin
    • COI: 1:CAS:528:DyaG3sXhs1KgsA%3D%3D, PID: 13022255
    • Bender IB, Pressman RS, Tashman SG. Studies on excretion of antibiotics in human saliva. I. Penicillin and streptomycin. J Am Dent Assoc. 1953;46:164–70.
    • (1953) J Am Dent Assoc. , vol.46 , pp. 164-170
    • Bender, I.B.1    Pressman, R.S.2    Tashman, S.G.3
  • 17
    • 23944517983 scopus 로고    scopus 로고
    • Measurement of tobramycin and gentamicin in saliva is not suitable for therapeutic drug monitoring of patients with cystic fibrosis
    • PID: 15994133
    • Spencer H, Kozlowska W, Davies JC, et al. Measurement of tobramycin and gentamicin in saliva is not suitable for therapeutic drug monitoring of patients with cystic fibrosis. J Cyst Fibros. 2005;4:209.
    • (2005) J Cyst Fibros. , vol.4 , pp. 209
    • Spencer, H.1    Kozlowska, W.2    Davies, J.C.3
  • 18
    • 0022618160 scopus 로고
    • Tissue penetration of ciprofloxacin after single and multiple doses
    • COI: 1:CAS:528:DyaL28Xhs1Wnu7g%3D, PID: 2940974
    • LeBel M, Vallee F, Bergeron MG. Tissue penetration of ciprofloxacin after single and multiple doses. Antimicrob Agents Chemother. 1986;29:501–5.
    • (1986) Antimicrob Agents Chemother. , vol.29 , pp. 501-505
    • LeBel, M.1    Vallee, F.2    Bergeron, M.G.3
  • 19
    • 0022590709 scopus 로고
    • Pharmacokinetics of ciprofloxacin in elderly subjects
    • COI: 1:STN:280:DyaL283jt1OmsA%3D%3D, PID: 2940518
    • LeBel M, Barbeau G, Bergeron MG, et al. Pharmacokinetics of ciprofloxacin in elderly subjects. Pharmacotherapy. 1986;6:87–91.
    • (1986) Pharmacotherapy. , vol.6 , pp. 87-91
    • LeBel, M.1    Barbeau, G.2    Bergeron, M.G.3
  • 20
    • 0025176079 scopus 로고
    • Levels of rifampin and ciprofloxacin in nasal secretions: correlation with MIC90 and eradication of nasopharyngeal carriage of bacteria
    • COI: 1:CAS:528:DyaK3MXlsFamtA%3D%3D, PID: 2121836
    • Darouiche R, Perkins B, Musher D, et al. Levels of rifampin and ciprofloxacin in nasal secretions: correlation with MIC90 and eradication of nasopharyngeal carriage of bacteria. J Infect Dis. 1990;162:1124–7.
    • (1990) J Infect Dis. , vol.162 , pp. 1124-1127
    • Darouiche, R.1    Perkins, B.2    Musher, D.3
  • 21
    • 0029807796 scopus 로고    scopus 로고
    • Relation between plasma and saliva concentrations of enoxacin, ciprofloxacin, and theophylline
    • COI: 1:CAS:528:DyaK2sXot1yj, PID: 8946663
    • Zhai S, Wei X, Parker BM, et al. Relation between plasma and saliva concentrations of enoxacin, ciprofloxacin, and theophylline. Ther Drug Monit. 1996;18:666–71.
    • (1996) Ther Drug Monit. , vol.18 , pp. 666-671
    • Zhai, S.1    Wei, X.2    Parker, B.M.3
  • 22
    • 0032817107 scopus 로고    scopus 로고
    • Kinetics of 4-fluoroquinolones permeation into saliva
    • COI: 1:CAS:528:DyaK1MXltFCgsL0%3D, PID: 10440793
    • Kozjek F, Suturkova LJ, Antolic G, et al. Kinetics of 4-fluoroquinolones permeation into saliva. Biopharm Drug Dispos. 1999;20:183–91.
    • (1999) Biopharm Drug Dispos. , vol.20 , pp. 183-191
    • Kozjek, F.1    Suturkova, L.J.2    Antolic, G.3
  • 23
    • 0036896404 scopus 로고    scopus 로고
    • Target site concentrations of ciprofloxacin after single intravenous and oral doses
    • COI: 1:CAS:528:DC%2BD38XptVyntro%3D, PID: 12435668
    • Brunner M, Stabeta H, Moller JG, et al. Target site concentrations of ciprofloxacin after single intravenous and oral doses. Antimicrob Agents Chemother. 2002;46:3724–30.
    • (2002) Antimicrob Agents Chemother. , vol.46 , pp. 3724-3730
    • Brunner, M.1    Stabeta, H.2    Moller, J.G.3
  • 24
    • 0028822282 scopus 로고
    • Effect of probenecid on the distribution and elimination of ciprofloxacin in humans
    • COI: 1:CAS:528:DyaK28XktlGltA%3D%3D, PID: 7586947
    • Jaehde U, Sorgel F, Reiter A, et al. Effect of probenecid on the distribution and elimination of ciprofloxacin in humans. Clin Pharmacol Ther. 1995;58:532–41.
    • (1995) Clin Pharmacol Ther. , vol.58 , pp. 532-541
    • Jaehde, U.1    Sorgel, F.2    Reiter, A.3
  • 25
    • 0021684622 scopus 로고
    • Multiple-dose pharmacokinetics and safety of ciprofloxacin in normal volunteers
    • COI: 1:CAS:528:DyaL2MXjvFCmsw%3D%3D, PID: 6517556
    • Gonzalez MA, Uribe F, Moisen SD, et al. Multiple-dose pharmacokinetics and safety of ciprofloxacin in normal volunteers. Antimicrob Agents Chemother. 1984;26:741–4.
    • (1984) Antimicrob Agents Chemother. , vol.26 , pp. 741-744
    • Gonzalez, M.A.1    Uribe, F.2    Moisen, S.D.3
  • 26
    • 0031004190 scopus 로고    scopus 로고
    • Utilization of salivary concentrations of ciprofloxacin in subjects with cystic fibrosis
    • COI: 1:CAS:528:DyaK2sXjt1aqsrw%3D, PID: 9108186
    • Smith A, Weber A, Pandher R, et al. Utilization of salivary concentrations of ciprofloxacin in subjects with cystic fibrosis. Infection. 1997;25:106–8.
    • (1997) Infection. , vol.25 , pp. 106-108
    • Smith, A.1    Weber, A.2    Pandher, R.3
  • 27
    • 0031903272 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and tolerability of ascending single doses of moxifloxacin, a new 8-methoxy quinolone, administered to healthy subjects
    • COI: 1:CAS:528:DyaK1cXltFKrsLo%3D, PID: 9687407
    • Stass H, Dalhoff A, Kubitza D, et al. Pharmacokinetics, safety, and tolerability of ascending single doses of moxifloxacin, a new 8-methoxy quinolone, administered to healthy subjects. Antimicrob Agents Chemother. 1998;42:2060–5.
    • (1998) Antimicrob Agents Chemother. , vol.42 , pp. 2060-2065
    • Stass, H.1    Dalhoff, A.2    Kubitza, D.3
  • 28
    • 0344721496 scopus 로고    scopus 로고
    • Penetration of moxifloxacin into peripheral compartments in humans
    • COI: 1:CAS:528:DyaK1MXms1Kqsr0%3D, PID: 10508004
    • Muller M, Stass H, Brunner M, et al. Penetration of moxifloxacin into peripheral compartments in humans. Antimicrob Agents Chemother. 1999;43:2345–9.
    • (1999) Antimicrob Agents Chemother. , vol.43 , pp. 2345-2349
    • Muller, M.1    Stass, H.2    Brunner, M.3
  • 29
    • 0036990101 scopus 로고    scopus 로고
    • Single- and multiple-dose pharmacokinetics of oral moxifloxacin and clarithromycin, and concentrations in serum, saliva and faeces
    • COI: 1:CAS:528:DC%2BD3sXit1Chtg%3D%3D
    • Burkhardt O, Borner K, Stass H, et al. Single- and multiple-dose pharmacokinetics of oral moxifloxacin and clarithromycin, and concentrations in serum, saliva and faeces. Scand J Respir Dis. 2002;34:898–903.
    • (2002) Scand J Respir Dis. , vol.34 , pp. 898-903
    • Burkhardt, O.1    Borner, K.2    Stass, H.3
  • 30
    • 0033853040 scopus 로고    scopus 로고
    • Impact of moxifloxacin versus clarithromycin on normal oropharyngeal microflora
    • COI: 1:CAS:528:DC%2BD3cXnvFSjs74%3D
    • Beyer G, Hiemer-Bau M, Ziege S, et al. Impact of moxifloxacin versus clarithromycin on normal oropharyngeal microflora. Eur J Clin Microbiol Infec Dis. 2000;19:548–50.
    • (2000) Eur J Clin Microbiol Infec Dis. , vol.19 , pp. 548-550
    • Beyer, G.1    Hiemer-Bau, M.2    Ziege, S.3
  • 31
    • 33749379014 scopus 로고    scopus 로고
    • Moxifloxacin distribution in the interstitial space of infected decubitus ulcer tissue of patients with spinal cord injury measured by in vivo microdialysis
    • COI: 1:CAS:528:DC%2BD28Xht1WjtLzP, PID: 17008236
    • Burkhardt O, Derendorf H, Jager D, et al. Moxifloxacin distribution in the interstitial space of infected decubitus ulcer tissue of patients with spinal cord injury measured by in vivo microdialysis. Scand J Infect Dis. 2006;38:904–8.
    • (2006) Scand J Infect Dis. , vol.38 , pp. 904-908
    • Burkhardt, O.1    Derendorf, H.2    Jager, D.3
  • 32
    • 0344721496 scopus 로고    scopus 로고
    • Penetration of moxifloxacin into peripheral compartments in humans
    • COI: 1:CAS:528:DyaK1MXms1Kqsr0%3D
    • Muller M, Stass H, Brunner M, et al. Penetration of moxifloxacin into peripheral compartments in humans. Antimicrob Agnets Chemother. 1999;43:2345–9.
    • (1999) Antimicrob Agnets Chemother. , vol.43 , pp. 2345-2349
    • Muller, M.1    Stass, H.2    Brunner, M.3
  • 33
    • 0029783256 scopus 로고    scopus 로고
    • Column-switching high-performance liquid chromatography of ofloxacin in human saliva and correlation of ofloxacin level in saliva and serum
    • COI: 1:CAS:528:DyaK28XmsFWitr0%3D, PID: 8885126
    • Ohkubo T, Suno M, Kudo M, et al. Column-switching high-performance liquid chromatography of ofloxacin in human saliva and correlation of ofloxacin level in saliva and serum. Ther Drug Monit. 1996;18:598–603.
    • (1996) Ther Drug Monit. , vol.18 , pp. 598-603
    • Ohkubo, T.1    Suno, M.2    Kudo, M.3
  • 34
    • 0036855248 scopus 로고    scopus 로고
    • Dose related pharmacokinetics of ofloxacin in healthy volunteers
    • COI: 1:STN:280:DC%2BD38jht1KqtA%3D%3D, PID: 12475149
    • Immanuel C, Hemanthkumar AK, Gurumurthy P, et al. Dose related pharmacokinetics of ofloxacin in healthy volunteers. Int J Tuberc Lung Dis. 2002;6:1017–22.
    • (2002) Int J Tuberc Lung Dis. , vol.6 , pp. 1017-1022
    • Immanuel, C.1    Hemanthkumar, A.K.2    Gurumurthy, P.3
  • 35
    • 0025194052 scopus 로고
    • Multiple-dose pharmacokinetics of ofloxacin in serum, saliva, and skin blister fluid of healthy volunteers
    • COI: 1:CAS:528:DyaK3cXptFWluw%3D%3D, PID: 2327762
    • Warlich R, Korting HC, Schafer-Korting M, et al. Multiple-dose pharmacokinetics of ofloxacin in serum, saliva, and skin blister fluid of healthy volunteers. Antimicrob Agents Chemother. 1990;34:78–81.
    • (1990) Antimicrob Agents Chemother. , vol.34 , pp. 78-81
    • Warlich, R.1    Korting, H.C.2    Schafer-Korting, M.3
  • 36
    • 0023612496 scopus 로고
    • Ofloxacin for prevention of bacterial infections in granulocytopenic patients
    • COI: 1:STN:280:DyaL1c7jvVCrsQ%3D%3D, PID: 3481358
    • Kern W, Kurrle E, Vanek E. Ofloxacin for prevention of bacterial infections in granulocytopenic patients. Infection. 1987;15:427–33.
    • (1987) Infection. , vol.15 , pp. 427-433
    • Kern, W.1    Kurrle, E.2    Vanek, E.3
  • 37
    • 0026544495 scopus 로고
    • Secretion of ofloxacin into saliva in patients with respiratory tract infection
    • COI: 1:STN:280:DyaK383gtF2luw%3D%3D, PID: 1551745
    • Takagi K, Hasegawa T, Yamaki K, et al. Secretion of ofloxacin into saliva in patients with respiratory tract infection. Int J Clin Pharmacol Ther Toxicol. 1992;30:46–50.
    • (1992) Int J Clin Pharmacol Ther Toxicol. , vol.30 , pp. 46-50
    • Takagi, K.1    Hasegawa, T.2    Yamaki, K.3
  • 38
    • 0028318192 scopus 로고
    • Effective monitoring of concentrations of ofloxacin in saliva of patients with chronic respiratory tract infections
    • COI: 1:STN:280:DyaK2czks1yhsg%3D%3D, PID: 8067752
    • Koizumi F, Ohnishi A, Takemura H, et al. Effective monitoring of concentrations of ofloxacin in saliva of patients with chronic respiratory tract infections. Antimicrob Agents Chemother. 1994;38:1140–3.
    • (1994) Antimicrob Agents Chemother. , vol.38 , pp. 1140-1143
    • Koizumi, F.1    Ohnishi, A.2    Takemura, H.3
  • 39
    • 0029126005 scopus 로고
    • Pharmacokinetics of ofloxacin: measurement of drug concentration in saliva of patients with impaired renal function
    • COI: 1:CAS:528:DyaK2MXptVSgt7g%3D, PID: 8549345
    • Fujita K, Matsuoka N, Takenaka I, et al. Pharmacokinetics of ofloxacin: measurement of drug concentration in saliva of patients with impaired renal function. Drugs. 1995;49:312–3.
    • (1995) Drugs. , vol.49 , pp. 312-313
    • Fujita, K.1    Matsuoka, N.2    Takenaka, I.3
  • 40
    • 0029078630 scopus 로고
    • Ofloxacin concentrations in serum, saliva and pleural effusion of patients with pulmonary tuberculosis and lung cancer
    • COI: 1:STN:280:DyaK28%2FjvVShsQ%3D%3D, PID: 7563589
    • Miya T, Hamakubo S, Goya T, et al. Ofloxacin concentrations in serum, saliva and pleural effusion of patients with pulmonary tuberculosis and lung cancer. Jpn J Antibiot. 1995;48:960–4.
    • (1995) Jpn J Antibiot. , vol.48 , pp. 960-964
    • Miya, T.1    Hamakubo, S.2    Goya, T.3
  • 41
    • 0028934495 scopus 로고
    • Hepatic cytochrome P450 enzyme imprinting in adult rat by neonatal benzo[a]pyrene administration
    • COI: 1:CAS:528:DyaK2MXlslClsrY%3D, PID: 7603785
    • Fujita I, Sindhu RK, Kikkawa Y. Hepatic cytochrome P450 enzyme imprinting in adult rat by neonatal benzo[a]pyrene administration. Pediatr Res. 1995;37:646–51.
    • (1995) Pediatr Res. , vol.37 , pp. 646-651
    • Fujita, I.1    Sindhu, R.K.2    Kikkawa, Y.3
  • 42
    • 0035986259 scopus 로고    scopus 로고
    • Multiple-dose pharmacokinetics and excretion balance of gatifloxacin, a new fluoroquinolone antibiotic, following oral administration to healthy Caucasian volunteers
    • COI: 1:CAS:528:DC%2BD38XlsFOnsr8%3D, PID: 12138326
    • Mignot A, Guillaume M, Brault M, et al. Multiple-dose pharmacokinetics and excretion balance of gatifloxacin, a new fluoroquinolone antibiotic, following oral administration to healthy Caucasian volunteers. Chemotherapy. 2002;48:116–21.
    • (2002) Chemotherapy. , vol.48 , pp. 116-121
    • Mignot, A.1    Guillaume, M.2    Brault, M.3
  • 43
    • 0023158756 scopus 로고
    • Effect of norfloxacin on human oropharyngeal and colonic microflora and multiple-dose pharmacokinetics
    • COI: 1:STN:280:DyaL2s7nslyjsg%3D%3D
    • Edlund C, Bergan T, Josefsson K, et al. Effect of norfloxacin on human oropharyngeal and colonic microflora and multiple-dose pharmacokinetics. Scand J Infec Dis. 1987;19:113–21.
    • (1987) Scand J Infec Dis. , vol.19 , pp. 113-121
    • Edlund, C.1    Bergan, T.2    Josefsson, K.3
  • 44
    • 0023628555 scopus 로고
    • Recovery of pefloxacin in saliva and feces and its action on oral and fecal floras of healthy volunteers
    • COI: 1:CAS:528:DyaL1cXhsFyltQ%3D%3D, PID: 3481248
    • Janin N, Meugnier H, Desnottes JF, et al. Recovery of pefloxacin in saliva and feces and its action on oral and fecal floras of healthy volunteers. Antimicrob Agents Chemother. 1987;31:1665–8.
    • (1987) Antimicrob Agents Chemother. , vol.31 , pp. 1665-1668
    • Janin, N.1    Meugnier, H.2    Desnottes, J.F.3
  • 45
    • 6844250096 scopus 로고    scopus 로고
    • Periodontal tissue disposition of azithromycin
    • COI: 1:CAS:528:DyaK1cXktlyhtg%3D%3D, PID: 9444596
    • Malizia T, Tejada MR, Ghelardi E, et al. Periodontal tissue disposition of azithromycin. J Periodontol. 1997;68:1206–9.
    • (1997) J Periodontol. , vol.68 , pp. 1206-1209
    • Malizia, T.1    Tejada, M.R.2    Ghelardi, E.3
  • 46
    • 0032875787 scopus 로고    scopus 로고
    • Periodontal tissue disposition of azithromycin in patients affected by chronic inflammatory periodontal diseases
    • COI: 1:CAS:528:DyaK1MXmsFOntbk%3D, PID: 10505797
    • Blandizzi C, Malizia T, Lupetti A, et al. Periodontal tissue disposition of azithromycin in patients affected by chronic inflammatory periodontal diseases. J Periodontol. 1999;70:960–6.
    • (1999) J Periodontol. , vol.70 , pp. 960-966
    • Blandizzi, C.1    Malizia, T.2    Lupetti, A.3
  • 47
    • 18244429752 scopus 로고    scopus 로고
    • Interaction between piroxicam and azithromycin during distribution to human periodontal tissues
    • COI: 1:CAS:528:DC%2BD3MXnsVCmu7w%3D, PID: 11577945
    • Malizia T, Batoni G, Ghelardi E, et al. Interaction between piroxicam and azithromycin during distribution to human periodontal tissues. J Periodontol. 2001;72:1151–6.
    • (2001) J Periodontol. , vol.72 , pp. 1151-1156
    • Malizia, T.1    Batoni, G.2    Ghelardi, E.3
  • 48
    • 84864697218 scopus 로고    scopus 로고
    • Saliva versus plasma pharmacokinetics: theory and application of a salivary excretion classification system
    • COI: 1:CAS:528:DC%2BC38XhtVShs7nJ, PID: 22784220
    • Idkaidek N, Arafat T. Saliva versus plasma pharmacokinetics: theory and application of a salivary excretion classification system. Mol Pharm. 2012;9:2358–63.
    • (2012) Mol Pharm. , vol.9 , pp. 2358-2363
    • Idkaidek, N.1    Arafat, T.2
  • 49
    • 0027203475 scopus 로고
    • Penetration of clarithromycin into human saliva
    • COI: 1:STN:280:DyaK3szotVekug%3D%3D, PID: 8370320
    • Wust J, Hardegger U. Penetration of clarithromycin into human saliva. Chemotherapy. 1993;39:293–6.
    • (1993) Chemotherapy. , vol.39 , pp. 293-296
    • Wust, J.1    Hardegger, U.2
  • 50
    • 0029024243 scopus 로고
    • Serum and cellular pharmacokinetics of clarithromycin 500 mg q.d. and 250 mg b.i.d. in volunteers
    • COI: 1:CAS:528:DyaK2MXnsF2mt7s%3D, PID: 7499006
    • Kees F, Wellenhofer M, Grobecker H. Serum and cellular pharmacokinetics of clarithromycin 500 mg q.d. and 250 mg b.i.d. in volunteers. Infection. 1995;23:168–72.
    • (1995) Infection. , vol.23 , pp. 168-172
    • Kees, F.1    Wellenhofer, M.2    Grobecker, H.3
  • 51
    • 0030017760 scopus 로고    scopus 로고
    • Effect of omeprazole on the distribution of metronidazole, amoxicillin, and clarithromycin in human gastric juice
    • COI: 1:CAS:528:DyaK28XkvFOnsLk%3D, PID: 8690200
    • Goddard AF, Jessa MJ, Barrett DA, et al. Effect of omeprazole on the distribution of metronidazole, amoxicillin, and clarithromycin in human gastric juice. Gastroenterology. 1996;111:358–67.
    • (1996) Gastroenterology. , vol.111 , pp. 358-367
    • Goddard, A.F.1    Jessa, M.J.2    Barrett, D.A.3
  • 52
    • 84880283669 scopus 로고    scopus 로고
    • Clinical validation of the analysis of linezolid and clarithromycin in oral fluid of patients with multidrug-resistant tuberculosis
    • COI: 1:CAS:528:DC%2BC3sXht1Wgtb7E, PID: 23689722
    • Bolhuis MS, van Altena R, van Hateren K, et al. Clinical validation of the analysis of linezolid and clarithromycin in oral fluid of patients with multidrug-resistant tuberculosis. Antimicrob Agents Chemother. 2013;57:3676–80.
    • (2013) Antimicrob Agents Chemother. , vol.57 , pp. 3676-3680
    • Bolhuis, M.S.1    van Altena, R.2    van Hateren, K.3
  • 53
    • 0018287596 scopus 로고
    • Plasma and saliva concentrations for a new formulation of erythromycin stearate
    • COI: 1:CAS:528:DyaE1MXlvFyrtrY%3D, PID: 467089
    • Berend N, Rutland J, Marlin GE. Plasma and saliva concentrations for a new formulation of erythromycin stearate. Curr Med Res Opin. 1979;6:118–23.
    • (1979) Curr Med Res Opin. , vol.6 , pp. 118-123
    • Berend, N.1    Rutland, J.2    Marlin, G.E.3
  • 54
    • 0019167813 scopus 로고
    • Plasma and salivary concentrations of erythromycin after administration of three different formulations
    • COI: 1:CAS:528:DyaL3MXntFelsg%3D%3D, PID: 7220406
    • Henry J, Turner P, Garland M, et al. Plasma and salivary concentrations of erythromycin after administration of three different formulations. Postgrad Med J. 1980;56:707–10.
    • (1980) Postgrad Med J. , vol.56 , pp. 707-710
    • Henry, J.1    Turner, P.2    Garland, M.3
  • 55
    • 0019846393 scopus 로고
    • The pharmacokinetics of two erythromycin esters in plasma and in saliva following oral administration in humans
    • COI: 1:CAS:528:DyaL38XhsV2muw%3D%3D, PID: 7298242
    • Ducci M, Scalori V, Del Tacca M, et al. The pharmacokinetics of two erythromycin esters in plasma and in saliva following oral administration in humans. Int J Clin Pharmacol Ther Toxicol. 1981;19:494–7.
    • (1981) Int J Clin Pharmacol Ther Toxicol. , vol.19 , pp. 494-497
    • Ducci, M.1    Scalori, V.2    Del Tacca, M.3
  • 56
    • 0018866474 scopus 로고
    • Factors determining the passage of drugs from blood into saliva
    • COI: 1:CAS:528:DyaL3cXhsVSgtbY%3D, PID: 7356893
    • Stephen KW, McCrossan J, Mackenzie D, et al. Factors determining the passage of drugs from blood into saliva. Br J Clin Pharmacol. 1980;9:51–5.
    • (1980) Br J Clin Pharmacol. , vol.9 , pp. 51-55
    • Stephen, K.W.1    McCrossan, J.2    Mackenzie, D.3
  • 57
    • 0030784932 scopus 로고    scopus 로고
    • Comparative pharmacokinetics of dirithromycin and erythromycin in normal volunteers with special regard to accumulation in polymorphonuclear leukocytes and in saliva
    • COI: 1:CAS:528:DyaK2sXnsVWqurw%3D, PID: 9403284
    • Geerdes-Fenge HF, Goetschi B, Rau M, et al. Comparative pharmacokinetics of dirithromycin and erythromycin in normal volunteers with special regard to accumulation in polymorphonuclear leukocytes and in saliva. Eur J Clin Pharmacol. 1997;53:127–33.
    • (1997) Eur J Clin Pharmacol. , vol.53 , pp. 127-133
    • Geerdes-Fenge, H.F.1    Goetschi, B.2    Rau, M.3
  • 58
    • 0027273204 scopus 로고
    • Penetration of penicillin V to tonsillar surface fluid in healthy individuals and in patients with acute tonsillitis
    • COI: 1:STN:280:DyaK3szgvVCmsg%3D%3D, PID: 8320515
    • Stjernquist-Desatnik A, Samuelsson P, Walder M. Penetration of penicillin V to tonsillar surface fluid in healthy individuals and in patients with acute tonsillitis. J Laryngol Otol. 1993;107:309–12.
    • (1993) J Laryngol Otol. , vol.107 , pp. 309-312
    • Stjernquist-Desatnik, A.1    Samuelsson, P.2    Walder, M.3
  • 59
    • 0025073754 scopus 로고
    • Roxithromycin penetration into gingiva and alveolar bone of odontoiatric patients
    • PID: 2119954
    • Del Tacca M, Danesi R, Bernardini N, et al. Roxithromycin penetration into gingiva and alveolar bone of odontoiatric patients. Chemotherapy. 1990;36:332–6.
    • (1990) Chemotherapy. , vol.36 , pp. 332-336
    • Del Tacca, M.1    Danesi, R.2    Bernardini, N.3
  • 60
    • 34948813706 scopus 로고    scopus 로고
    • Plasma and salivary amoxicillin concentrations and effect against oral microorganisms
    • COI: 1:CAS:528:DC%2BD2sXhtlWjsL3M, PID: 17966841
    • Baglie S, Del Ruenis AP, Motta RH, et al. Plasma and salivary amoxicillin concentrations and effect against oral microorganisms. Int J Clin Pharmacol Ther. 2007;45:556–62.
    • (2007) Int J Clin Pharmacol Ther. , vol.45 , pp. 556-562
    • Baglie, S.1    Del Ruenis, A.P.2    Motta, R.H.3
  • 61
    • 0035999156 scopus 로고    scopus 로고
    • Amoxicillin and ampicillin are not transferred to gastric juice irrespective of Helicobacter pylori status or acid blockade by omeprazole
    • COI: 1:CAS:528:DC%2BD38XlslSisb8%3D
    • Ortiz RA, Calafatti SA, Corazzi A, et al. Amoxicillin and ampicillin are not transferred to gastric juice irrespective of Helicobacter pylori status or acid blockade by omeprazole. Ailment Pharmacol Ther. 2002;16:1163–70.
    • (2002) Ailment Pharmacol Ther. , vol.16 , pp. 1163-1170
    • Ortiz, R.A.1    Calafatti, S.A.2    Corazzi, A.3
  • 62
    • 0025396914 scopus 로고
    • Concentrations of ampicillin in human serum and mixed saliva following a single oral administration of lenampicillin, and relationship between serum and mixed saliva concentrations
    • COI: 1:CAS:528:DyaK3cXltVyltbs%3D, PID: 2345375
    • Akimoto Y, Mochizuki Y, Uda A, et al. Concentrations of ampicillin in human serum and mixed saliva following a single oral administration of lenampicillin, and relationship between serum and mixed saliva concentrations. J Nihon Univ Sch Dent. 1990;32:14–8.
    • (1990) J Nihon Univ Sch Dent. , vol.32 , pp. 14-18
    • Akimoto, Y.1    Mochizuki, Y.2    Uda, A.3
  • 63
    • 0015116171 scopus 로고
    • Comparison of human serum, parotid and mixed saliva levels of phenoxymethylpenicillin, ampicillin, cloxacillin and cephalexin
    • COI: 1:CAS:528:DyaE38XjtVKksA%3D%3D
    • Speirs CF, Stenhouse D, Stephen KW, et al. Comparison of human serum, parotid and mixed saliva levels of phenoxymethylpenicillin, ampicillin, cloxacillin and cephalexin. Br J Clin Pharmacol. 1971;43:242–7.
    • (1971) Br J Clin Pharmacol. , vol.43 , pp. 242-247
    • Speirs, C.F.1    Stenhouse, D.2    Stephen, K.W.3
  • 64
    • 85018167179 scopus 로고
    • Treatment of chronic bronchitis with ampicillin: some pharmacological observation
    • May JR, Delves DM. Treatment of chronic bronchitis with ampicillin: some pharmacological observation. Lancet. 1965;1:233.
    • (1965) Lancet. , vol.1 , pp. 233
    • May, J.R.1    Delves, D.M.2
  • 65
    • 0014791817 scopus 로고
    • Ampicillin levels in sputum, serum, and saliva
    • COI: 1:STN:280:DyaE3c3mvVeltA%3D%3D, PID: 4318047
    • Stewart SM, Fisher M, Young JE, et al. Ampicillin levels in sputum, serum, and saliva. Thorax. 1970;25:304–11.
    • (1970) Thorax. , vol.25 , pp. 304-311
    • Stewart, S.M.1    Fisher, M.2    Young, J.E.3
  • 66
    • 0023611471 scopus 로고
    • Concentrations of phenoxymethylpenicillin and cefadroxil in tonsillar tissue and tonsillar surface fluid
    • COI: 1:STN:280:DyaL1c7jslamug%3D%3D, PID: 3125047
    • Stromberg A, Friberg U, Cars O. Concentrations of phenoxymethylpenicillin and cefadroxil in tonsillar tissue and tonsillar surface fluid. Eur J Clin Microbiol. 1987;6:525–9.
    • (1987) Eur J Clin Microbiol. , vol.6 , pp. 525-529
    • Stromberg, A.1    Friberg, U.2    Cars, O.3
  • 67
    • 0023239393 scopus 로고
    • Penicillin concentration in saliva and its influence on bacterial interference
    • COI: 1:STN:280:DyaL2s3ptFyrsg%3D%3D, PID: 3112934
    • Grahn E, Holm SE. Penicillin concentration in saliva and its influence on bacterial interference. Scand J Infect Dis. 1987;19:235–41.
    • (1987) Scand J Infect Dis. , vol.19 , pp. 235-241
    • Grahn, E.1    Holm, S.E.2
  • 68
    • 0032437953 scopus 로고    scopus 로고
    • Saliva-resistant coating of tablets prevents oral release of penicillin: plasma but not saliva equivalence
    • COI: 1:CAS:528:DyaK1cXnvVyntbg%3D, PID: 9923579
    • Quiding H, Arwidsson HG, Grahn E, et al. Saliva-resistant coating of tablets prevents oral release of penicillin: plasma but not saliva equivalence. Eur J Clin Pharmacol. 1998;54:749–52.
    • (1998) Eur J Clin Pharmacol. , vol.54 , pp. 749-752
    • Quiding, H.1    Arwidsson, H.G.2    Grahn, E.3
  • 69
    • 0025962974 scopus 로고
    • Pharmacokinetics of cefotiam in plasma, parotid saliva and mixed saliva in healthy adults
    • COI: 1:CAS:528:DyaK3MXitl2rtLg%3D, PID: 1867664
    • Zerfowski M, Schlegel P, Maier H. Pharmacokinetics of cefotiam in plasma, parotid saliva and mixed saliva in healthy adults. Arzneimittelforschung. 1991;41:257–9.
    • (1991) Arzneimittelforschung. , vol.41 , pp. 257-259
    • Zerfowski, M.1    Schlegel, P.2    Maier, H.3
  • 70
    • 84861230289 scopus 로고    scopus 로고
    • Saliva and blood concentration of cefuroxime in patients undergoing maxillofacial surgery
    • PID: 22459228
    • Venetis G, Chatzika K, Pitsiou G, et al. Saliva and blood concentration of cefuroxime in patients undergoing maxillofacial surgery. J Oral Maxillofac Surg. 2012;70:1398–403.
    • (2012) J Oral Maxillofac Surg. , vol.70 , pp. 1398-1403
    • Venetis, G.1    Chatzika, K.2    Pitsiou, G.3
  • 71
    • 0018888055 scopus 로고
    • Sputum and blood concentrations of cefuroxime in lower respiratory tract infection
    • COI: 1:STN:280:DyaL3M%2Fls1yktQ%3D%3D, PID: 7434289
    • Havard CW, Bax RP, Samanta TC, et al. Sputum and blood concentrations of cefuroxime in lower respiratory tract infection. Thorax. 1980;35:379–83.
    • (1980) Thorax. , vol.35 , pp. 379-383
    • Havard, C.W.1    Bax, R.P.2    Samanta, T.C.3
  • 72
    • 0016044636 scopus 로고
    • Entry of four tetracyclines into saliva and tears
    • COI: 1:CAS:528:DyaE2cXktV2murY%3D, PID: 4840441
    • Hoeprich PD, Warshauer DM. Entry of four tetracyclines into saliva and tears. Antimicrob Agents Chemother. 1974;5:330–6.
    • (1974) Antimicrob Agents Chemother. , vol.5 , pp. 330-336
    • Hoeprich, P.D.1    Warshauer, D.M.2
  • 73
    • 0031792083 scopus 로고    scopus 로고
    • The pharmacokinetic profile of a biodegradable controlled-release delivery system containing doxycycline compared to systemically delivered doxycycline in gingival crevicular fluid, saliva, and serum
    • COI: 1:CAS:528:DyaK1cXntFGitr4%3D, PID: 9802705
    • Stoller NH, Johnson LR, Trapnell S, et al. The pharmacokinetic profile of a biodegradable controlled-release delivery system containing doxycycline compared to systemically delivered doxycycline in gingival crevicular fluid, saliva, and serum. J Periodontol. 1998;69:1085–91.
    • (1998) J Periodontol. , vol.69 , pp. 1085-1091
    • Stoller, N.H.1    Johnson, L.R.2    Trapnell, S.3
  • 74
    • 0033627769 scopus 로고    scopus 로고
    • Concentration of 3 tetracyclines in plasma, gingival crevice fluid and saliva
    • COI: 1:CAS:528:DC%2BD3cXmsV2gsA%3D%3D, PID: 10674962
    • Sakellari D, Goodson JM, Kolokotronis A, et al. Concentration of 3 tetracyclines in plasma, gingival crevice fluid and saliva. J Clin Periodontol. 2000;27:53–60.
    • (2000) J Clin Periodontol. , vol.27 , pp. 53-60
    • Sakellari, D.1    Goodson, J.M.2    Kolokotronis, A.3
  • 75
    • 84455173000 scopus 로고    scopus 로고
    • Penetration of doripenem into skeletal muscle and subcutaneous adipose tissue in healthy volunteers
    • COI: 1:CAS:528:DC%2BC38Xjt1Kiuw%3D%3D
    • Burian B, Zeitlinger M, Donath O, et al. Penetration of doripenem into skeletal muscle and subcutaneous adipose tissue in healthy volunteers. Antimicrob Agnets Chemother. 2012;56:532–5.
    • (2012) Antimicrob Agnets Chemother. , vol.56 , pp. 532-535
    • Burian, B.1    Zeitlinger, M.2    Donath, O.3
  • 76
    • 84959113546 scopus 로고    scopus 로고
    • Hara S, Uchiyama M, Toshinari M, et al. A simple high-performance liquid chromatography for the determination of linezolid in human plasma and saliva. Biomed Chromatogr. 2015:3441–2 (Epub ahead of print)
    • Hara S, Uchiyama M, Toshinari M, et al. A simple high-performance liquid chromatography for the determination of linezolid in human plasma and saliva. Biomed Chromatogr. 2015:3441–2 (Epub ahead of print).
  • 77
    • 0022873593 scopus 로고
    • Metronidazole concentrations in human plasma, saliva, and gingival crevice fluid after a single dose
    • PID: 3097094
    • Van Oosten MA, Notten FJ, Mikx FH. Metronidazole concentrations in human plasma, saliva, and gingival crevice fluid after a single dose. J Dent Res. 1986;65:1420–3.
    • (1986) J Dent Res. , vol.65 , pp. 1420-1423
    • Van Oosten, M.A.1    Notten, F.J.2    Mikx, F.H.3
  • 78
    • 0028523037 scopus 로고
    • Kinetics of spiramycin/metronidazole (Rodogyl) in human gingival crevicular fluid, saliva and blood
    • COI: 1:STN:280:DyaK2M7gsFemsA%3D%3D, PID: 7806675
    • Rotzetter PA, Le Liboux A, Pichard E, et al. Kinetics of spiramycin/metronidazole (Rodogyl) in human gingival crevicular fluid, saliva and blood. J Clin Periodontol. 1994;21:595–600.
    • (1994) J Clin Periodontol. , vol.21 , pp. 595-600
    • Rotzetter, P.A.1    Le Liboux, A.2    Pichard, E.3
  • 79
    • 14844290295 scopus 로고    scopus 로고
    • Metronidazole concentrations in plasma, saliva and periodontal pockets in patients with periodontitis
    • PID: 15691346
    • Pahkla ER, Koppel T, Saaq M, et al. Metronidazole concentrations in plasma, saliva and periodontal pockets in patients with periodontitis. J Clin Periodontol. 2005;32:163–6.
    • (2005) J Clin Periodontol. , vol.32 , pp. 163-166
    • Pahkla, E.R.1    Koppel, T.2    Saaq, M.3
  • 80
    • 85047689732 scopus 로고
    • Rifampin. Levels in serum and saliva and effect on the meningococcal carrier state
    • COI: 1:STN:280:DyaE3M%2FhvVGqug%3D%3D, PID: 4990906
    • Devine LF, Johnson DP, Hagerman CR, et al. Rifampin. Levels in serum and saliva and effect on the meningococcal carrier state. JAMA. 1970;214:1055–9.
    • (1970) JAMA. , vol.214 , pp. 1055-1059
    • Devine, L.F.1    Johnson, D.P.2    Hagerman, C.R.3
  • 81
    • 0015011370 scopus 로고
    • Rifampin: effect of two-day treatment on the meningococcal carrier state and the relationship to the levels of drug in sera and saliva
    • COI: 1:STN:280:DyaE3M7lt1Kqtg%3D%3D, PID: 5550138
    • Devine LF, Johnson DP, Rhode SL, et al. Rifampin: effect of two-day treatment on the meningococcal carrier state and the relationship to the levels of drug in sera and saliva. Am J Med Sci. 1971;261:79–83.
    • (1971) Am J Med Sci. , vol.261 , pp. 79-83
    • Devine, L.F.1    Johnson, D.P.2    Rhode, S.L.3
  • 82
    • 0018953735 scopus 로고
    • Pharmacokinetics of rifampin in infants and children: relevance to prophylaxis against Haemophilus influenzae type b disease
    • PID: 6967586
    • McCracken GH, Ginsburg CM, Zweighaft RC, et al. Pharmacokinetics of rifampin in infants and children: relevance to prophylaxis against Haemophilus influenzae type b disease. Pediatrics. 1980;66:17–21.
    • (1980) Pediatrics. , vol.66 , pp. 17-21
    • McCracken, G.H.1    Ginsburg, C.M.2    Zweighaft, R.C.3
  • 83
    • 5444248130 scopus 로고    scopus 로고
    • Some plasma and saliva pharmacokinetics parameters of rifampicin in the presence of pefloxacin
    • PID: 15266220
    • Orisakwe OE, Akunyili DN, Agbasi PU, et al. Some plasma and saliva pharmacokinetics parameters of rifampicin in the presence of pefloxacin. Am J Ther. 2004;11:283–7.
    • (2004) Am J Ther. , vol.11 , pp. 283-287
    • Orisakwe, O.E.1    Akunyili, D.N.2    Agbasi, P.U.3
  • 84
    • 84921438379 scopus 로고    scopus 로고
    • Effect of ofloxacin and norfloxacin on rifampicin pharmacokinetics in man
    • PID: 23817346
    • Ezejiofor NA, Brown S, Barikpoar E, et al. Effect of ofloxacin and norfloxacin on rifampicin pharmacokinetics in man. Am J Ther. 2015;22:29–36.
    • (2015) Am J Ther. , vol.22 , pp. 29-36
    • Ezejiofor, N.A.1    Brown, S.2    Barikpoar, E.3
  • 85
    • 67849109992 scopus 로고    scopus 로고
    • A fast reverse-phase high performance liquid chromatographic tandem mass spectrometry assay for the quantification of clindamycin in plasma and saliva using a rapid resolution package
    • COI: 1:CAS:528:DC%2BD1MXpt1Kgtb0%3D, PID: 19269123
    • Catena E, Perez G, Sadaba B, et al. A fast reverse-phase high performance liquid chromatographic tandem mass spectrometry assay for the quantification of clindamycin in plasma and saliva using a rapid resolution package. J Pharm Biomed Anal. 2009;50:649–54.
    • (2009) J Pharm Biomed Anal. , vol.50 , pp. 649-654
    • Catena, E.1    Perez, G.2    Sadaba, B.3


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