Saliva versus plasma pharmacokinetics: Theory and application of a salivary excretion classification system

Molecular Pharmaceutics

Volumn 9, Issue 8, 2012, Pages 2358-2363

  Idkaidek, Nasir ^a   Arafat, Tawfiq ^a  

^a UNIVERSITY OF PETRA   (Jordan)

Author keywords

bioequivalence; effective permeability; pharmacokinetics; protein binding; Salivary Excretion Classification System; SimCYP

Indexed keywords

AZITHROMYCIN; CINACALCET; CLOXACILLIN; DIACEREIN; HYDROCHLOROTHIAZIDE; LORNOXICAM; LOSARTAN; METFORMIN; MONTELUKAST; ROSUVASTATIN; SITAGLIPTIN; TAMSULOSIN; TOLTERODINE;

ALGORITHM; AREA UNDER THE CURVE; ARTICLE; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; DRUG BLOOD LEVEL; DRUG DIFFUSION; DRUG EXCRETION; DRUG HALF LIFE; DRUG PENETRATION; DRUG PROTEIN BINDING; EFFECTIVE INTESTINAL PERMEABILITY; FEMALE; HUMAN; HUMAN EXPERIMENT; MAXIMUM PLASMA CONCENTRATION; NELDER MEAD METHOD; NORMAL HUMAN; PHARMACOKINETICS; PHYSICAL CHEMISTRY; PLASMA; PRIORITY JOURNAL; SALIVA; SALIVARY EXCRETION CLASSIFICATION SYSTEM; THEORETICAL MODEL; TIME TO MAXIMUM PLASMA CONCENTRATION;

ACETATES; ANTHRAQUINONES; AZITHROMYCIN; BENZHYDRYL COMPOUNDS; CLOXACILLIN; CRESOLS; FEMALE; FLUOROBENZENES; HUMANS; HYDROCHLOROTHIAZIDE; LOSARTAN; MALE; METFORMIN; NAPHTHALENES; PHENYLPROPANOLAMINE; PIROXICAM; PYRAZINES; PYRIMIDINES; QUINOLINES; SALIVA; SULFONAMIDES; TRIAZOLES;

EID: 84864697218     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300250r     Document Type: Article

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