Rapid and sensitive analysis of reduced and oxidized coenzyme Q10 in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and application to studies in healthy human subjects

Annals of Clinical Biochemistry

Volumn 53, Issue 2, 2016, Pages 265-273

  Claessens, Adam J ^a   Yeung, Catherine K ^a,b   Risler, Linda J ^a   Phillips, Brian R ^a   Himmelfarb, Jonathan ^b   Shen, Danny D ^a,c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c Fred Hutchinson Cancer Research Center   (United States)

Author keywords

oxidized CoQ10; plasma concentrations; reduced Coq10; stability; UPLC MS MS

Indexed keywords

1,4 BENZOQUINONE; ALCOHOL; ANTICOAGULANT AGENT; COENZYME Q9; PROPANOL; SOLVENT; UBIDECARENONE; UNCLASSIFIED DRUG; UBIQUINONE;

ACCURACY; ARTICLE; BLOOD SAMPLING; COENZYME; CONTROLLED STUDY; FLOW RATE; HUMAN; LIMIT OF QUANTITATION; OXIDATION; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SOLVENT EXTRACTION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANALOGS AND DERIVATIVES; BLOOD; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; NORMAL HUMAN; OXIDATION REDUCTION REACTION; PROCEDURES; SPECIMEN HANDLING; VALIDATION STUDY;

CHROMATOGRAPHY, LIQUID; HEALTHY VOLUNTEERS; HUMANS; LIMIT OF DETECTION; OXIDATION-REDUCTION; SPECIMEN HANDLING; TANDEM MASS SPECTROMETRY; UBIQUINONE;

EID: 84959110074     PISSN: 00045632     EISSN: 17581001     Source Type: Journal    
DOI: 10.1177/0004563215593097     Document Type: Article

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