Farnesol increases the susceptibility of Burkholderia pseudomallei biofilm to antimicrobials used to treat melioidosis

Journal of Applied Microbiology

Volumn 120, Issue 3, 2016, Pages 600-606

  Castelo Branco, D S C M ^a   Riello, G B ^a   Vasconcelos, D C ^a   Guedes, G M M ^a   Serpa, R ^a   Bandeira, T J P G ^a   Monteiro, A J ^a   Cordeiro, R A ^a   Rocha, M F G ^a,b   Sidrim, J J C ^a   Brilhante, R S N ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b STATE UNIVERSITY OF CEARÁ   (Brazil)

Author keywords

Burkholderia pseudomallei; Biofilm; Farnesol; Melioidosis; Susceptibility

Indexed keywords

MICROORGANISMS;

AMOXICILLIN; ANTIBACTERIAL DRUGS; BURKHOLDERIA PSEUDOMALLEI; CEFTAZIDIME; DOXYCYCLINE; FARNESOL; MELIOIDOSIS; SULFAMETHOXAZOLE; SUSCEPTIBILITY; TRIMETHOPRIM;

BIOFILMS;

AMOXICILLIN; CEFTAZIDIME; COTRIMOXAZOLE; DOXYCYCLINE; FARNESOL; RESAZURIN; ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; BACTERIUM; BIOFILM; DISEASE TREATMENT; DRUG; DYE; INFECTIOUS DISEASE; MICROBIAL ACTIVITY; ORGANIC COMPOUND; OXIDATION; REDUCTION;

ANTIBIOTIC SENSITIVITY; ARTICLE; BIOFILM; BROTH DILUTION; BURKHOLDERIA PSEUDOMALLEI; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; MELIOIDOSIS; MINIMUM BIOFILM ERADICATION CONCENTRATION; NONHUMAN; DRUG EFFECTS; HUMAN; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; PHYSIOLOGY; PROCEDURES;

BURKHOLDERIA PSEUDOMALLEI;

AMOXICILLIN; ANTI-BACTERIAL AGENTS; BIOFILMS; BURKHOLDERIA PSEUDOMALLEI; CEFTAZIDIME; FARNESOL; HUMANS; MELIOIDOSIS; MICROBIAL SENSITIVITY TESTS; TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION;

EID: 84959055191     PISSN: 13645072     EISSN: 13652672     Source Type: Journal    
DOI: 10.1111/jam.13027     Document Type: Article

References (32)

1. Allison, D.G. and Sutherland, I.W. (1984) A staining technique for attached bacteria and its correlation to extracellular carbohydrate production. J Microbiol Methods 2, 93-99.
2. Bandeira, T.J.P.G., Moreira, C.A., Brilhante, R.S.N., Castelo-Branco, D.S.C.M., Neto, M.P.A., Cordeiro, R.A., Rodrigues, T.J.S., Rocha, M.F.G. et al. (2013) In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei. Antimicrob Agents Chemother 57, 5771-5773.
3. Bell, S. and Chappell, J. (2014) Now playing: farnesol in the biofilm. Chem Biol 21, 1421-1422.
4. Brilhante, R.S.N., Bandeira, T.J.P.G., Cordeiro, R.A., Grangeiro, T.B., Lima, R.A.C., Ribeiro, J.F., Castelo-Branco, D.S.C.M., Rodrigues, J.L.N. et al. (2012a) Clinical-epidemiological features of 13 cases of melioidosis in Brazil. J Clin Microbiol 50, 3349-3352.
5. Brilhante, R.S.N., Valente, L.G.A., Rocha, M.F.G., Bandeira, T.J.P.G., Cordeiro, R.A., Lima, R.A.C., Leite, J.J.G., Ribeiro, J.F. et al. (2012b) Sesquiterpene farnesol contributes to increased susceptibility to β-lactams in strains of Burkholderia pseudomallei. Antimicrob Agents Chemother 56, 2198-2200.
6. Cerca, N., Gomes, F., Pereira, S., Teixeira, P. and Oliveira, R. (2012) Confocal laser scanning microscopy analysis of S. epidermidis biofilms exposed to farnesol, vancomycin and rifampicin. BMC Res Notes, 5, 244.
7. Chen, Y.S., Shieh, W.J., Goldsmith, C.S., Metcalfe, M.G., Greer, P.W., Zaki, S.R., Chang, H.H., Chan, H. et al. (2014) Alteration of the phenotypic and pathogenic Patterns of Burkholderia pseudomallei that persist in a soil environment. Am J Trop Med Hyg 90, 469-479.
8. CLSI. (2010) Methods for Antimicrobial Dilution and Disk Susceptibility Testing of Infrequently Isolated or Fastidious Bacteria. CLSI document M45-A2. Wayne, PA, USA: Clinical and Laboratory Standards Institute.
9. CLSI. (2012a) Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically. CLSI document M7-A9. Wayne, PA, USA: Clinical and Laboratory Standards Institute.
10. CLSI. (2012b) Performance Standards for Antimicrobial Susceptibility Testing?; Twenty-Second Informational Supplement. CLSI document M100-S22. Wayne, PA, USA: Clinical and Laboratory Standards Institute.
11. Currie, B.J. (2015) Melioidosis: evolving concepts in epidemiology, pathogenesis, and treatment. Semin Respir Crit Care Med 36, 111-125.
12. Dance, D. (2014) Treatment and prophylaxis of melioidosis. Int J Antimicrob Agents 43, 310-318.
13. Foong, Y.C., Tan, M. and Bradbury, R.S. (2014) Melioidosis: a review. Rural Remote Health 14, 2763.
14. Hengzhuang, W., Ciofu, O., Yang, L., Wu, H., Song, Z., Oliver, A. and Høibya, N. (2013) High β-lactamase levels change the pharmacodynamics of β-lactam antibiotics in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother 57, 196-204.
15. Heydorn, A., Nielsen, A.T., Morten Hentzer, M., Sternberg, C., Givskov, M., Ersbøll, B.J. and Molin, S. (2000) Quantification of biofilm structures by the novel computer program COMSTAT. Image Process 146, 2395-2407.
16. Horev, B., Klein, M.I., Hwang, G., Li, Y., Kim, D., Koo, H. and Benoit, D.S.W. (2015) pH-activated nanoparticles for controlled topical delivery of farnesol to disrupt oral biofilm virulence. ACS Nano, 9, 2390-2404.
17. Jin, J., Zhang, J., Guo, N., Sheng, H., Li, L., Liang, J.C., Wang, X.L., Li, Y. et al. (2010) Farnesol, a potential efflux pump inhibitor in Mycobacterium smegmatis. Molecules 15, 7750-7762.
18. Katragkou, A., Mccarthy, M., Alexander, E.L., Antachopoulos, C., Meletiadis, J., Jabra-Rizk, M.A., Petraitis, V., Roilides, E. et al. (2014) In vitro interactions between farnesol and fluconazole, amphotericin B or micafungin against Candida albicans biofilms. J Antimicrob Chemother 70, 470-478.
19. Koh, S., Tay, S. and Puthucheary, S. (2013) Colonial morphotypes and biofilm forming ability of Burkholderia pseudomallei. Trop Biomed 30, 428-433.
20. Kuroda, M., Nagasaki, S. and Ohta, T. (2007) Sesquiterpene farnesol inhibits recycling of the C 55 lipid carrier of the murein monomer precursor contributing to increased susceptibility to β-lactams in methicillin-resistant Staphylococcus aureus. J Antimicrob Chemother 59, 425-432.
21. Lazar, A.N.R., Dean, R.E., Saint, R.J., Stevens, M.P., Prior, J.L., Atkins, T.P. and Galyov, E.E. (2013) Identification of a predicted trimeric autotransporter adhesin required for biofilm formation of Burkholderia pseudomallei. PLoS ONE 8, e79461.
22. Limmathurotsakul, D., Paeyao, A., Wongratanacheewin, S., Saiprom, N., Takpho, N., Thaipadungpanit, J., Chantratita, N., Wuthiekanun, V. et al. (2014) Role of Burkholderia pseudomallei biofilm formation and lipopolysaccharide in relapse of melioidosis Introduction. Clin Microbiol Infect, 20, O854-O856.
23. Macedo, R.N., Rocha, F.A., Rolim, D.B., Vilar, D.C.L.F., Araújo, F.M.D.C., Vieira, N.N., Teixeira, J.R., Carvalho, M.C. et al. (2012) Severe coinfection of melioidosis and dengue fever in northeastern Brazil: first case report. Rev Soc Bras Med Trop 45, 132-133.
24. Mima, T. and Schweizer, H.P. (2010) The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. Antimicrob Agents Chemother 54, 3113-3120.
25. Peeters, E., Nelis, H.J. and Coenye, T. (2008) Comparison of multiple methods for quantification of microbial biofilms grown in microtiter plates. J Microbiol Methods 72, 157-165.
26. Rolim, D.B., Vilar, D.C.F.L., De Goés Cavalcanti, L.P., Freitas, L.B.N., Inglis, T.J.J., Rodrigues, J.L.N. and Nagao-Dias, A.T. (2011) Burkholderia pseudomallei antibodies in individuals living in endemic regions in Northeastern Brazil. Am J Trop Med Hyg 84, 302-305.
27. Roveta, S., Schito, A.M., Marchese, A. and Schito, G.C. (2007) Activity of moxifloxacin on biofilms produced in vitro by bacterial pathogens involved in acute exacerbations of chronic bronchitis. Int J Antimicrob Agents 30, 415-421.
28. Saini, H., Chhibber, S. and Harjai, K. (2014) Azithromycin and ciprofloxacin: a possible synergistic combination against Pseudomonas aeruginosa biofilm-associated urinary tract infections. Int J Antimicrob Agents, 45, 359-367.
29. Sarovich, D.S., Price, E.P., Limmathurotsakul, D., Cook, J.M., von Schulze, A.T., Wolken, S.R., Keim, P., Refidaff, C. et al. (2012) Development of ceftazidime resistance in an acute Burkholderia pseudomallei infection. Infect Drug Resist 5, 129-132.
30. Sharma, M. and Prasad, R. (2011) The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans. Antimicrob Agents Chemother 55, 4834-4843.
31. Tran, P.L., Hammond, A.A., Mosley, T., Cortez, J., Gray, T., Colmer-Hamood, J.A., Shashtri, M., Spallholz, J.E. et al. (2009) Organoselenium coating on cellulose inhibits the formation of biofilms by Pseudomonas aeruginosa and Staphylococcus aureus. Appl Environ Microbiol 75, 3586-3592.
32. Yu, H.G., Chung, H., Young, S., Seo, J.M. and Heo, J.W. (2003) A new rapid and non-radioactive assay for monitoring and determining the proliferation of retinal pigment epithelial cells. Korean J Ophthalmol 17, 29-34.