Sequential ionic and conformational signaling by calcium channels drives neuronal gene expression

Science

Volumn 351, Issue 6275, 2016, Pages 863-867

  Li, Boxing ^a   Tadross, Michael R ^b,c   Tsien, Richard W ^a,b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CHANNEL; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NIMODIPINE; PROTEIN KINASE C; PURINERGIC P2X2 RECEPTOR; SHORT HAIRPIN RNA; VOLTAGE GATED CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; L-TYPE CALCIUM CHANNEL ALPHA(1C);

CALCIUM; CELLS AND CELL COMPONENTS; ENZYME; GENE EXPRESSION; LIGAND; NEUROLOGY; PROTEIN; SYMPTOM;

ARTICLE; AUTISM; BIOACCUMULATION; CLINICAL ASSESSMENT; CONFORMATIONAL TRANSITION; CYTOSKELETON; GENE EXPRESSION; GENETIC ANALYSIS; HEART DISEASE; HUMAN; IMMUNOPRECIPITATION; MEMBRANE DEPOLARIZATION; MEMBRANE PERMEABILITY; MOLECULAR INTERACTION; NERVE CELL; NEUROPSYCHIATRY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TIMOTHY SYNDROME; ANIMAL; CALCIUM SIGNALING; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; HIPPOCAMPUS; LONG QT SYNDROME; METABOLISM; NERVE CELL PLASTICITY; PROTEIN CONFORMATION; RAT; SPRAGUE DAWLEY RAT; SYNAPSE; SYNDACTYLY;

PHLEUM PRATENSE;

ANIMALS; AUTISTIC DISORDER; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GENE EXPRESSION REGULATION; HEK293 CELLS; HIPPOCAMPUS; HUMANS; LONG QT SYNDROME; NEURONAL PLASTICITY; NEURONS; NIMODIPINE; PROTEIN CONFORMATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPSES; SYNDACTYLY;

EID: 84958979199     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aad3647     Document Type: Article

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