Short Communication: The Broad-Spectrum Histone Deacetylase Inhibitors Vorinostat and Panobinostat Activate Latent HIV in CD4+ T Cells in Part Through Phosphorylation of the T-Loop of the CDK9 Subunit of P-TEFb

AIDS Research and Human Retroviruses

Volumn 32, Issue 2, 2016, Pages 169-173

  Jamaluddin, Md Saha ^a   Hu, Pei Wen ^a   Jan, Yih ^a   Siwak, Edward B ^a   Rice, Andrew P ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CYCLIN DEPENDENT KINASE 9; CYCLIN T1; HISTONE H3; PANOBINOSTAT; ROMIDEPSIN; TACEDINALINE; VORINOSTAT; ACETYLDINALINE; CCNT1 PROTEIN, HUMAN; CDK9 PROTEIN, HUMAN; CYCLIN T; DEPSIPEPTIDE; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; INDOLE DERIVATIVE; PHENYLENEDIAMINE DERIVATIVE; POSITIVE TRANSCRIPTION ELONGATION FACTOR B;

ARTICLE; CD4+ T LYMPHOCYTE; ENZYME PHOSPHORYLATION; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HISTONE ACETYLATION; HUMAN IMMUNODEFICIENCY VIRUS; LATENT VIRUS INFECTION; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; VIRUS REACTIVATION; CELL CULTURE; DRUG EFFECTS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HIV INFECTIONS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; PHOSPHORYLATION; PROVIRUS; VIROLOGY; VIRUS ACTIVATION; VIRUS LATENCY; VIRUS REPLICATION;

ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CYCLIN T; CYCLIN-DEPENDENT KINASE 9; DEPSIPEPTIDES; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, VIRAL; HISTONE DEACETYLASE INHIBITORS; HIV INFECTIONS; HIV-1; HUMANS; HYDROXAMIC ACIDS; INDOLES; PHENYLENEDIAMINES; PHOSPHORYLATION; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; PROVIRUSES; VIRUS ACTIVATION; VIRUS LATENCY; VIRUS REPLICATION;

EID: 84958961184     PISSN: 08892229     EISSN: 19318405     Source Type: Journal    
DOI: 10.1089/aid.2015.0347     Document Type: Article

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