Levosimendan for prevention of acute kidney injury after cardiac surgery: A meta-analysis of randomized controlled trials

American Journal of Kidney Diseases

Volumn 67, Issue 3, 2016, Pages 408-416

  Zhou, Chenghui ^a   Gong, Junsong ^a   Chen, Dong ^a   Wang, Weipeng ^a   Liu, Mingzheng ^a   Liu, Bin ^b  

^a FUWAI HOSPITAL   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; DOBUTAMINE; LEVOSIMENDAN; MILRINONE; HYDRAZONE DERIVATIVE; PROTECTIVE AGENT; PYRIDAZINE DERIVATIVE; SIMENDAN; VASODILATOR AGENT;

ACUTE KIDNEY FAILURE; ARTICLE; ARTIFICIAL VENTILATION; CONTINUOUS INFUSION; COUNTERPULSATION; CREATININE BLOOD LEVEL; HEART SURGERY; HOSPITALIZATION; HUMAN; INTENSIVE CARE UNIT; INTRAAORTIC BALLOON PUMP; LENGTH OF STAY; LOADING DRUG DOSE; META ANALYSIS; PERIOPERATIVE PERIOD; RANDOMIZED CONTROLLED TRIAL (TOPIC); RENAL REPLACEMENT THERAPY; SENSITIVITY ANALYSIS; SURGICAL MORTALITY; ACUTE KIDNEY INJURY; ADULT; ADVERSE EFFECTS; DRUG EFFECTS; KIDNEY; OUTCOME ASSESSMENT; POSTOPERATIVE COMPLICATIONS; PROCEDURES;

ACUTE KIDNEY INJURY; ADULT; CARDIAC SURGICAL PROCEDURES; HUMANS; HYDRAZONES; KIDNEY; OUTCOME ASSESSMENT (HEALTH CARE); POSTOPERATIVE COMPLICATIONS; PROTECTIVE AGENTS; PYRIDAZINES; RANDOMIZED CONTROLLED TRIALS AS TOPIC; VASODILATOR AGENTS;

EID: 84958888586     PISSN: 02726386     EISSN: 15236838     Source Type: Journal    
DOI: 10.1053/j.ajkd.2015.09.015     Document Type: Article

References (51)

1. F. Ryckwaert, G. Boccara, J.M. Frappier, and P.H. Colson Incidence, risk factors, and prognosis of a moderate increase in plasma creatinine early after cardiac surgery Crit Care Med 30 2002 1495 1498
2. M. Stafford-Smith, M. Podgoreanu, M. Swaminathan, and et al. Association of genetic polymorphisms with risk of renal injury after coronary bypass graft surgery Am J Kidney Dis 45 2005 519 530
3. J.R. Brown, R.P. Cochran, L.J. Dacey, and et al. Perioperative increases in serum creatinine are predictive of increased 90-day mortality after coronary artery bypass graft surgery Circulation 114 2006 I409 I413
4. J.L. Koyner, M.R. Bennett, E.M. Worcester, and et al. Urinary cystatin C as an early biomarker of acute kidney injury following adult cardiothoracic surgery Kidney Int 74 2008 1059 1069
5. C.E. Hobson, S. Yavas, M.S. Segal, and et al. Acute kidney injury is associated with increased long-term mortality after cardiothoracic surgery Circulation 119 2009 2444 2453
6. R.F. Zimmerman, P.U. Ezeanuna, J.C. Kane, and et al. Ischemic preconditioning at a remote site prevents acute kidney injury in patients following cardiac surgery Kidney Int 80 2011 861 867
7. A. Lassnigg, D. Schmidlin, M. Mouhieddine, and et al. Minimal changes of serum creatinine predict prognosis in patients after cardiothoracic surgery: a prospective cohort study J Am Soc Nephrol 15 2004 1597 1605
8. A. Lassnigg, E.R. Schmid, M. Hiesmayr, and et al. Impact of minimal increases in serum creatinine on outcome in patients after cardiothoracic surgery: do we have to revise current definitions of acute renal failure? Crit Care Med 36 2008 1129 1137
9. J.W. Pickering, M.T. James, and S.C. Palmer Acute kidney injury and prognosis after cardiopulmonary bypass: a meta-analysis of cohort studies Am J Kidney Dis 65 2015 283 293
10. T.B. Ferguson Jr., B.G. Hammill, E.D. Peterson, E.R. DeLong, and F.L. Grover A decade of change-risk profiles and outcomes for isolated coronary artery bypass grafting procedures, 1990-1999: a report from the STS National Database Committee and the Duke Clinical Research Institute. Society of Thoracic Surgeons Ann Thorac Surg 73 2002 480 489 discussion 489-490
11. A.M. Gaffney, and R.N. Sladen Acute kidney injury in cardiac surgery Curr Opin Anaesthesiol 28 2015 50 59
12. K.E. Burns, M.W. Chu, R.J. Novick, and et al. Perioperative N-acetylcysteine to prevent renal dysfunction in high-risk patients undergoing CABG surgery: a randomized controlled trial JAMA 294 2005 342 350
13. T. Bove, A. Zangrillo, F. Guarracino, and et al. Effect of fenoldopam on use of renal replacement therapy among patients with acute kidney injury after cardiac surgery: a randomized clinical trial JAMA 312 2014 2244 2253
14. M. Haase, A. Haase-Fielitz, M. Plass, and et al. Prophylactic perioperative sodium bicarbonate to prevent acute kidney injury following open heart surgery: a multicenter double-blinded randomized controlled trial PLoS Med 10 2013 e1001426
15. F. Follath, J.G. Cleland, H. Just, and et al. Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): a randomised double-blind trial Lancet 360 2002 196 202
16. V.S. Moiseyev, P. Poder, N. Andrejevs, and et al. Safety and efficacy of a novel calcium sensitizer, levosimendan, in patients with left ventricular failure due to an acute myocardial infarction. A randomized, placebo-controlled, double-blind study (RUSSLAN) Eur Heart J 23 2002 1422 1432
17. R.A. Zager, A.C. Johnson, S. Lund, S.Y. Hanson, and C.K. Abrass Levosimendan protects against experimental endotoxemic acute renal failure Am J Physiol Renal Physiol 290 2006 F1453 F1462
18. N. Yakut, H. Yasa, B. Bahriye Lafci, and et al. The influence of levosimendan and iloprost on renal ischemia-reperfusion: an experimental study Interact Cardiovasc Thorac Surg 7 2008 235 239
19. E. Grossini, C. Molinari, P. Pollesello, and et al. Levosimendan protection against kidney ischemia/reperfusion injuries in anesthetized pigs J Pharmacol Exp Ther 342 2012 376 388
20. E. Al-Shawaf, A. Ayed, I. Vislocky, B. Radomir, N. Dehrab, and R. Tarazi Levosimendan or milrinone in the type 2 diabetic patient with low ejection fraction undergoing elective coronary artery surgery J Cardiothorac Vasc Anesth 20 2006 353 357
21. S.G. De Hert, S. Lorsomradee, S. Cromheecke, and P.J. Van der Linden The effects of levosimendan in cardiac surgery patients with poor left ventricular function Anesth Analg 104 2007 766 773
22. L. Tritapepe, V. De Santis, D. Vitale, and et al. Levosimendan pre-treatment improves outcomes in patients undergoing coronary artery bypass graft surgery Br J Anaesth 102 2009 198 204
23. D. Moher, A. Liberati, J. Tetzlaff, and D.G. Altman Preferred Reporting Items for Systematic Reviews and Meta-analyses: the PRISMA statement PLoS Med 6 2009 e1000097
24. S.P. Hozo, B. Djulbegovic, and I. Hozo Estimating the mean and variance from the median, range, and the size of a sample BMC Med Res Methodol 5 2005 13
25. P. Sharma, A. Malhotra, S. Gandhi, P. Garg, A. Bishnoi, and H. Gandhi Preoperative levosimendan in ischemic mitral valve repair Asian Cardiovasc Thorac Ann 22 2013 539 545
26. G. Bragadottir, B. Redfors, and S.E. Ricksten Effects of levosimendan on glomerular filtration rate, renal blood flow, and renal oxygenation after cardiac surgery with cardiopulmonary bypass: a randomized placebo-controlled study Crit Care Med 41 2013 2328 2335
27. P. Lahtinen, O. Pitkanen, P. Polonen, A. Turpeinen, V. Kiviniemi, and A. Uusaro Levosimendan reduces heart failure after cardiac surgery: a prospective, randomized, placebo-controlled trial Crit Care Med 39 2011 2263 2270
28. R. Levin, M. Degrange, C. Del Mazo, E. Tanus, and R. Porcile Preoperative levosimendan decreases mortality and the development of low cardiac output in high-risk patients with severe left ventricular dysfunction undergoing coronary artery bypass grafting with cardiopulmonary bypass Exp Clin Cardiol 17 2012 125 130
29. B. Shah, P. Sharma, A. Brahmbhatt, and et al. Study of levosimendan during off-pump coronary artery bypass grafting in patients with LV dysfunction: a double-blind randomized study Indian J Pharmacol 46 2014 29 34
30. A. Baysal, M. Yanartas, M. Dogukan, N. Gundogus, T. Kocak, and C. Koksal Levosimendan improves renal outcome in cardiac surgery: a randomized trial J Cardiothorac Vasc Anesth 28 2014 586 594
31. A. Ristikankare, R. Poyhia, H. Eriksson, M. Valtonen, K. Leino, and M. Salmenpera Effects of levosimendan on renal function in patients undergoing coronary artery surgery J Cardiothorac Vasc Anesth 26 2012 591 595
32. R.L. Levin, M.A. Degrange, R. Porcile, and et al. [The calcium sensitizer levosimendan gives superior results to dobutamine in postoperative low cardiac Output Syndrome] Rev Esp Cardiol 61 2008 471 479
33. R. Levin, R. Rafael Porcile, F. Salvagio, and et al. Levosimendan reduces mortality in postoperative low cardiac output syndrome after coronary surgery. Annual Meeting of American Heart Association Circulation 120 suppl 18 2009 S987 S988
34. J. Erb, T. Beutlhauser, A. Feldheiser, and et al. Influence of levosimendan on organ dysfunction in patients with severely reduced left ventricular function undergoing cardiac surgery J Int Med Res 42 2014 750 764
35. A.M. O'Hare, J. Feinglass, A.N. Sidawy, and et al. Impact of renal insufficiency on short-term morbidity and mortality after lower extremity revascularization: data from the Department of Veterans Affairs' National Surgical Quality Improvement Program J Am Soc Nephrol 14 2003 1287 1295
36. J.M. Vieira Jr., I. Castro, A. Curvello-Neto, and et al. Effect of acute kidney injury on weaning from mechanical ventilation in critically ill patients Crit Care Med 35 2007 184 191
37. J.F. Dasta, S.L. Kane-Gill, A.J. Durtschi, D.S. Pathak, and J.A. Kellum Costs and outcomes of acute kidney injury (AKI) following cardiac surgery Nephrol Dial Transplant 23 2008 1970 1974
38. A. Falvo, H.M. Horst, I. Rubinfeld, and et al. Acute renal failure in cardiothoracic surgery patients: what is the best definition of this common and potent predictor of increased morbidity and mortality Am J Surg 196 2008 379 383
39. Z.Z. Niu, S.M. Wu, W.Y. Sun, W.M. Hou, and Y.F. Chi Perioperative levosimendan therapy is associated with a lower incidence of acute kidney injury after cardiac surgery: a meta-analysis J Cardiovasc Pharmacol 63 2014 107 112
40. M. Schetz, T. Bove, A. Morelli, S. Mankad, C. Ronco, and J.A. Kellum Prevention of cardiac surgery-associated acute kidney injury Int J Artific Organs 31 2008 179 189
41. P.G. Metnitz, C.G. Krenn, H. Steltzer, and et al. Effect of acute renal failure requiring renal replacement therapy on outcome in critically ill patients Crit Care Med 30 2002 2051 2058
42. M. Che, Y. Li, X. Liang, and et al. Prevalence of acute kidney injury following cardiac surgery and related risk factors in Chinese patients Nephron Clin Pract 117 2011 c305 c311
43. K. Dickstein, A. Cohen-Solal, G. Filippatos, and et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM) Eur Heart J 29 2008 2388 2442
44. G. Landoni, G. Biondi-Zoccai, M. Greco, and et al. Effects of levosimendan on mortality and hospitalization. A meta-analysis of randomized controlled studies Crit Care Med 40 2012 634 646
45. W. Toller, L. Algotsson, F. Guarracino, and et al. Perioperative use of levosimendan: best practice in operative settings J Cardiothorac Vasc Anesth 27 2013 361 366
46. Z. Papp, I. Edes, S. Fruhwald, and et al. Levosimendan: molecular mechanisms and clinical implications: consensus of experts on the mechanisms of action of levosimendan Int J Cardiol 159 2012 82 87
47. F.J. Abelha, M. Botelho, V. Fernandes, and H. Barros Determinants of postoperative acute kidney injury Crit Care 13 2009 R79
48. Y. Hu, Z. Li, J. Chen, C. Shen, Y. Song, and Q. Zhong Risk factors for acute kidney injury in patients undergoing same admission coronary angiography and valve replacement J Cardiac Surg 28 2013 627 631
49. W.H. Kim, M.H. Park, H.J. Kim, and et al. Potentially modifiable risk factors for acute kidney injury after surgery on the thoracic aorta: a propensity score matched case-control study Medicine (Baltimore) 94 2015 e273
50. J. Cai, R. Xu, X. Yu, Y. Fang, and X. Ding Volatile anesthetics in preventing acute kidney injury after cardiac surgery: a systematic review and meta-analysis J Thorac Cardiovasc Surg 148 2014 3127 3136
51. I. Singh, S. Rajagopalan, A. Srinivasan, and et al. Preoperative statin therapy is associated with lower requirement of renal replacement therapy in patients undergoing cardiac surgery: a meta-analysis of observational studies Interact Cardiovasc Thorac Surg 17 2013 345 352