Effects of levosimendan on renal function in patients undergoing coronary artery surgery

Journal of Cardiothoracic and Vascular Anesthesia

Volumn 26, Issue 4, 2012, Pages 591-595

  Ristikankare, Anne ^a   Pöyhiä, Reino ^a   Eriksson, Heidi ^a   Valtonen, Mika ^b   Leino, Kari ^b   Salmenperä, Markku ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b TURKU UNIVERSITY HOSPITAL   (Finland)

Author keywords

acute kidney injury; coronary artery surgery; levosimendan

Indexed keywords

CREATININE; CYSTATIN C; EPHEDRINE; INSULIN; LEVOSIMENDAN; MILRINONE; N ACETYL BETA GLUCOSAMINIDASE; PHENYLEPHRINE; PLACEBO; PROPOFOL; ROCURONIUM; SUFENTANIL; VASOPRESSIN;

ACUTE KIDNEY FAILURE; ANESTHESIA INDUCTION; AORTA CLAMPING; ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; CORONARY ARTERY BYPASS SURGERY; CREATININE BLOOD LEVEL; DISEASE MARKER; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG INFUSION; GLOMERULUS FILTRATION RATE; HUMAN; HYPOTENSION; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MULTIPLE ORGAN FAILURE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; URINE LEVEL;

ACETYLGLUCOSAMINIDASE; ACUTE KIDNEY INJURY; ADULT; CARDIOPULMONARY BYPASS; CARDIOTONIC AGENTS; CORONARY ARTERY BYPASS; CREATININE; CYSTATIN C; DOUBLE-BLIND METHOD; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; HYDRAZONES; KIDNEY; MALE; PROSPECTIVE STUDIES; PYRIDAZINES;

EID: 84863492112     PISSN: 10530770     EISSN: 15328422     Source Type: Journal    
DOI: 10.1053/j.jvca.2012.01.035     Document Type: Article

References (24)

1. M.H. Rosner, M.D. Okusa Acute kidney injury associated with cardiac surgery Clin J Am Soc Nephrol 1 2006 19 32
2. A. Lassnigg, D. Schmidlin, M. Mouhieddine Minimal changes of serum creatinine predict prognosis in patients after cardiothoracic surgery: A prospective cohort study J Am Soc Nephrol 15 2004 1597 1605 (Pubitemid 38679685)
3. B.G. Loef, A.H. Epema, T.D. Smilde Immediate postoperative renal function deterioration in cardiac surgical patients predicts in-hospital mortality and long-term survival J Am Soc Nephrol 16 2005 195 200 (Pubitemid 43073173)
4. K. Karkouti, D.N. Wijeysundera, T.M. Yau Acute kidney injury after cardiac surgery: Focus on modifiable risk factors Circulation 119 2009 495 502
5. B.G. Loef, A.H. Epema, G. Navis Postoperative renal dysfunction and preoperative left ventricular dysfunction predispose patients to increased long-term mortality after coronary artery bypass graft surgery Br J Anaesth 102 2009 749 755
6. J. Lilleberg, M.S. Nieminen, J. Akkila Effects of a new calcium sensitizer, levosimendan, on haemodynamics, coronary blood flow and myocardial substrate utilization early after coronary artery bypass grafting Eur Heart J 19 1998 660 668 (Pubitemid 28224690)
7. J.R. Kersten, M.W. Montgomery, P.S. Pagel Levosimendan, a new positive inotropic drug, decreases myocardial infarct size via activation of K(ATP) channels Anesth Analg 90 2000 5 11 (Pubitemid 30022959)
8. G. Landoni, A. Mizzi, G. Biondi-Zoccai Levosimendan reduces mortality in critically ill patients A meta-analysis of randomized controlled studies Minerva Anestesiol 76 2010 276 286
9. G. Landoni, A. Mizzi, G. Biondi-Zoccai Reducing mortality in cardiac surgery with levosimendan: a meta-analysis of randomized controlled trials J Cardiothorac Vasc Anesth 24 2010 51 57
10. J. Puttonen, S. Kantele, M. Kivikko Effect of severe renal failure and haemodialysis on the pharmacokinetics of levosimendan and its metabolites Clin Pharmacokinet 46 2007 235 246 (Pubitemid 46425649)
11. M.B. Yilmaz, K. Yalta, C. Yontar Levosimendan improves renal function in patients with acute decompensated heart failure: Comparison with dobutamine Cardiovasc Drugs Ther 21 2007 431 435 (Pubitemid 350231513)
12. R.A. Zager, A.C. Johnson, S. Lund Levosimendan protects against experimental endotoxemic acute renal failure Am J Physiol Ren Physiol 290 2006 F1453 F1462
13. H.I. Eriksson, J.R. Jalonen, L.O. Heikkinen Levosimendan facilitates weaning from cardiopulmonary bypass in patients undergoing coronary artery bypass grafting with impaired left ventricular function Ann Thorac Surg 87 2009 448 454
14. R. Bellomo, C. Ronco, J.A. Kellum Acute renal failure - Definition, outcome measures, animal models, fluid therapy and information technology needs: The Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group Crit Care 8 2004 R204 R212
15. A. Haase-Fielitz, R. Bellomo, P. Devarajan Novel and conventional serum biomarkers predicting acute kidney injury in adult cardiac surgery - A prospective cohort study Crit Care Med 37 2009 553 560
16. M. Haase, R. Bellomo, P. Devarajan Novel biomarkers early predict the severity of acute kidney injury after cardiac surgery in adults Ann Thorac Surg 88 2009 124 130
17. S.M. Jakob, E. Ruokonen, J. Takala Effects of dopamine on systemic and regional blood flow and metabolism in septic and cardiac surgery patients Shock 18 2002 8 13
18. P.S. Pagel, D.A. Hettrick, D.C. Warltier Influence of levosimendan, pimobendan, and milrinone on the regional distribution of cardiac output in anaesthetized dogs Br J Pharmacol 119 1996 609 615 (Pubitemid 26335328)
19. J.F. Buckley, M. Singer, L.H. Clapp Role of KATP channels in sepsis Cardiovasc Res 72 2006 220 230
20. K. Pompermayer, D.G. Souza, G.G. Lara The ATP-sensitive potassium channel blocker glibenclamide prevents renal ischemia/reperfusion injury in rats Kidney Int 67 2005 1785 1796 (Pubitemid 40577713)
21. M. Salmenperä, H. Eriksson Levosimendan in perioperative and critical care patients Curr Opin Anaesthesiol 22 2009 496 501
22. V. Faivre, H. Kaskos, J. Callebert Cardiac and renal effects of levosimendan, arginine vasopressin, and norepinephrine in lipopolysaccharide- treated rabbits Anesthesiology 103 2005 514 521 (Pubitemid 41243413)
23. A. Oldner, D. Konrad, E. Weitzberg Effects of levosimendan, a novel inotropic calcium-sensitizing drug, in experimental septic shock Crit Care Med 29 2001 2185 2193 (Pubitemid 33063549)
24. A. Morelli, S. De Castro, J.L. Teboul Effects of levosimendan on systemic and regional hemodynamics in septic myocardial depression Intensive Care Med 31 2005 638 644 (Pubitemid 40684980)