-
1
-
-
0032543607
-
Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo
-
Bolton S.J., Anthony D.C., Perry V.H. Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo. Neuroscience 1998, 86:1245-1257.
-
(1998)
Neuroscience
, vol.86
, pp. 1245-1257
-
-
Bolton, S.J.1
Anthony, D.C.2
Perry, V.H.3
-
2
-
-
79956328903
-
Molecular mechanisms and clinical applications of angiogenesis
-
Carmeliet P., Jain R.K. Molecular mechanisms and clinical applications of angiogenesis. Nature 2011, 473:298-307.
-
(2011)
Nature
, vol.473
, pp. 298-307
-
-
Carmeliet, P.1
Jain, R.K.2
-
3
-
-
84902156978
-
ARF6 inhibition stabilizes the vasculature and enhances survival during endotoxic shock
-
Davis C.T., Zhu W., Gibson C.C., Bowman-Kirigin J.A., Sorensen L., Ling J., Sun H., Navankasattusas S., Li D.Y. ARF6 inhibition stabilizes the vasculature and enhances survival during endotoxic shock. J. Immunol. 2014, 192:6045-6052.
-
(2014)
J. Immunol.
, vol.192
, pp. 6045-6052
-
-
Davis, C.T.1
Zhu, W.2
Gibson, C.C.3
Bowman-Kirigin, J.A.4
Sorensen, L.5
Ling, J.6
Sun, H.7
Navankasattusas, S.8
Li, D.Y.9
-
4
-
-
0036782278
-
VEGF and the quest for tumour angiogenesis factors
-
Ferrara N. VEGF and the quest for tumour angiogenesis factors. Nat. Rev. Cancer 2002, 2:795-803.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 795-803
-
-
Ferrara, N.1
-
5
-
-
48449098623
-
Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs
-
Gascoigne K.E., Taylor S.S. Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. Cancer Cell 2008, 14:111-122.
-
(2008)
Cancer Cell
, vol.14
, pp. 111-122
-
-
Gascoigne, K.E.1
Taylor, S.S.2
-
6
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
Gerlinger M., Rowan A.J., Horswell S., Larkin J., Endesfelder D., Gronroos E., Martinez P., Matthews N., Stewart A., Tarpey P., et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N. Engl. J. Med. 2012, 366:883-892.
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
Larkin, J.4
Endesfelder, D.5
Gronroos, E.6
Martinez, P.7
Matthews, N.8
Stewart, A.9
Tarpey, P.10
-
7
-
-
84875168586
-
The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis
-
ra14
-
Grossmann A.H., Yoo J.H., Clancy J., Sorensen L.K., Sedgwick A., Tong Z., Ostanin K., Rogers A., Grossmann K.F., Tripp S.R., et al. The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis. Sci. Signal. 2013, 6. ra14.
-
(2013)
Sci. Signal.
, vol.6
-
-
Grossmann, A.H.1
Yoo, J.H.2
Clancy, J.3
Sorensen, L.K.4
Sedgwick, A.5
Tong, Z.6
Ostanin, K.7
Rogers, A.8
Grossmann, K.F.9
Tripp, S.R.10
-
8
-
-
79151483638
-
An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients
-
Györffy B., Lanczky A., Eklund A.C., Denkert C., Budczies J., Li Q., Szallasi Z. An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients. Breast Cancer Res. Treat. 2010, 123:725-731.
-
(2010)
Breast Cancer Res. Treat.
, vol.123
, pp. 725-731
-
-
Györffy, B.1
Lanczky, A.2
Eklund, A.C.3
Denkert, C.4
Budczies, J.5
Li, Q.6
Szallasi, Z.7
-
9
-
-
0026497186
-
Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer
-
Horak E.R., Leek R., Klenk N., LeJeune S., Smith K., Stuart N., Greenall M., Stepniewska K., Harris A.L. Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer. Lancet 1992, 340:1120-1124.
-
(1992)
Lancet
, vol.340
, pp. 1120-1124
-
-
Horak, E.R.1
Leek, R.2
Klenk, N.3
LeJeune, S.4
Smith, K.5
Stuart, N.6
Greenall, M.7
Stepniewska, K.8
Harris, A.L.9
-
10
-
-
0036209165
-
Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis
-
Huminiecki L., Gorn M., Suchting S., Poulsom R., Bicknell R. Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis. Genomics 2002, 79:547-552.
-
(2002)
Genomics
, vol.79
, pp. 547-552
-
-
Huminiecki, L.1
Gorn, M.2
Suchting, S.3
Poulsom, R.4
Bicknell, R.5
-
11
-
-
41849131420
-
Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability
-
Jones C.A., London N.R., Chen H., Park K.W., Sauvaget D., Stockton R.A., Wythe J.D., Suh W., Larrieu-Lahargue F., Mukouyama Y.S., et al. Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability. Nat. Med. 2008, 14:448-453.
-
(2008)
Nat. Med.
, vol.14
, pp. 448-453
-
-
Jones, C.A.1
London, N.R.2
Chen, H.3
Park, K.W.4
Sauvaget, D.5
Stockton, R.A.6
Wythe, J.D.7
Suh, W.8
Larrieu-Lahargue, F.9
Mukouyama, Y.S.10
-
12
-
-
70449529782
-
Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity
-
Jones C.A., Nishiya N., London N.R., Zhu W., Sorensen L.K., Chan A.C., Lim C.J., Chen H., Zhang Q., Schultz P.G., et al. Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity. Nat. Cell Biol. 2009, 11:1325-1331.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1325-1331
-
-
Jones, C.A.1
Nishiya, N.2
London, N.R.3
Zhu, W.4
Sorensen, L.K.5
Chan, A.C.6
Lim, C.J.7
Chen, H.8
Zhang, Q.9
Schultz, P.G.10
-
13
-
-
34250365240
-
Mechanisms of adverse effects of anti-VEGF therapy for cancer
-
Kamba T., McDonald D.M. Mechanisms of adverse effects of anti-VEGF therapy for cancer. Br. J. Cancer 2007, 96:1788-1795.
-
(2007)
Br. J. Cancer
, vol.96
, pp. 1788-1795
-
-
Kamba, T.1
McDonald, D.M.2
-
14
-
-
78651433171
-
Robo4 maintains vessel integrity and inhibits angiogenesis by interacting with UNC5B
-
Koch A.W., Mathivet T., Larrivée B., Tong R.K., Kowalski J., Pibouin-Fragner L., Bouvrée K., Stawicki S., Nicholes K., Rathore N., et al. Robo4 maintains vessel integrity and inhibits angiogenesis by interacting with UNC5B. Dev. Cell 2011, 20:33-46.
-
(2011)
Dev. Cell
, vol.20
, pp. 33-46
-
-
Koch, A.W.1
Mathivet, T.2
Larrivée, B.3
Tong, R.K.4
Kowalski, J.5
Pibouin-Fragner, L.6
Bouvrée, K.7
Stawicki, S.8
Nicholes, K.9
Rathore, N.10
-
15
-
-
0021261333
-
Breast cancer: relationship between the size of the primary tumour and the probability of metastatic dissemination
-
Koscielny S., Tubiana M., Lê M.G., Valleron A.J., Mouriesse H., Contesso G., Sarrazin D. Breast cancer: relationship between the size of the primary tumour and the probability of metastatic dissemination. Br. J. Cancer 1984, 49:709-715.
-
(1984)
Br. J. Cancer
, vol.49
, pp. 709-715
-
-
Koscielny, S.1
Tubiana, M.2
Lê, M.G.3
Valleron, A.J.4
Mouriesse, H.5
Contesso, G.6
Sarrazin, D.7
-
16
-
-
77951836880
-
Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza
-
23ra19
-
London N.R., Zhu W., Bozza F.A., Smith M.C., Greif D.M., Sorensen L.K., Chen L., Kaminoh Y., Chan A.C., Passi S.F., et al. Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza. Sci. Transl. Med. 2010, 2. 23ra19.
-
(2010)
Sci. Transl. Med.
, vol.2
-
-
London, N.R.1
Zhu, W.2
Bozza, F.A.3
Smith, M.C.4
Greif, D.M.5
Sorensen, L.K.6
Chen, L.7
Kaminoh, Y.8
Chan, A.C.9
Passi, S.F.10
-
17
-
-
77953803209
-
Vascular Robo4 restricts proangiogenic VEGF signaling in breast
-
Marlow R., Binnewies M., Sorensen L.K., Monica S.D., Strickland P., Forsberg E.C., Li D.Y., Hinck L. Vascular Robo4 restricts proangiogenic VEGF signaling in breast. Proc. Natl. Acad. Sci. U. S. A 2010, 107:10520-10525.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A
, vol.107
, pp. 10520-10525
-
-
Marlow, R.1
Binnewies, M.2
Sorensen, L.K.3
Monica, S.D.4
Strickland, P.5
Forsberg, E.C.6
Li, D.Y.7
Hinck, L.8
-
18
-
-
63249115113
-
Loss of tight junction barrier function and its role in cancer metastasis
-
Martin T.A., Jiang W.G. Loss of tight junction barrier function and its role in cancer metastasis. Biochim. Biophys. Acta 2009, 1788:872-891.
-
(2009)
Biochim. Biophys. Acta
, vol.1788
, pp. 872-891
-
-
Martin, T.A.1
Jiang, W.G.2
-
19
-
-
0042663890
-
Robo4 is a vascular-specific receptor that inhibits endothelial migration
-
Park K.W., Morrison C.M., Sorensen L.K., Jones C.A., Rao Y., Chien C.B., Wu J.Y., Urness L.D., Li D.Y. Robo4 is a vascular-specific receptor that inhibits endothelial migration. Dev. Biol. 2003, 261:251-267.
-
(2003)
Dev. Biol.
, vol.261
, pp. 251-267
-
-
Park, K.W.1
Morrison, C.M.2
Sorensen, L.K.3
Jones, C.A.4
Rao, Y.5
Chien, C.B.6
Wu, J.Y.7
Urness, L.D.8
Li, D.Y.9
-
20
-
-
84937758440
-
Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization
-
Rama N., Dubrac A., Mathivet T., Ní Chárthaigh R.A., Genet G., Cristofaro B., Pibouin-Fragner L., Ma L., Eichmann A., Chédotal A. Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization. Nat. Med. 2015, 21:483-491.
-
(2015)
Nat. Med.
, vol.21
, pp. 483-491
-
-
Rama, N.1
Dubrac, A.2
Mathivet, T.3
Ní Chárthaigh, R.A.4
Genet, G.5
Cristofaro, B.6
Pibouin-Fragner, L.7
Ma, L.8
Eichmann, A.9
Chédotal, A.10
-
21
-
-
0034234623
-
Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression
-
Salcedo R., Ponce M.L., Young H.A., Wasserman K., Ward J.M., Kleinman H.K., Oppenheim J.J., Murphy W.J. Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression. Blood 2000, 96:34-40.
-
(2000)
Blood
, vol.96
, pp. 34-40
-
-
Salcedo, R.1
Ponce, M.L.2
Young, H.A.3
Wasserman, K.4
Ward, J.M.5
Kleinman, H.K.6
Oppenheim, J.J.7
Murphy, W.J.8
-
22
-
-
78650974913
-
Robo4 cooperates with CXCR4 to specify hematopoietic stem cell localization to bone marrow niches
-
Smith-Berdan S., Nguyen A., Hassanein D., Zimmer M., Ugarte F., Ciriza J., Li D., García-Ojeda M.E., Hinck L., Forsberg E.C. Robo4 cooperates with CXCR4 to specify hematopoietic stem cell localization to bone marrow niches. Cell Stem Cell 2011, 8:72-83.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 72-83
-
-
Smith-Berdan, S.1
Nguyen, A.2
Hassanein, D.3
Zimmer, M.4
Ugarte, F.5
Ciriza, J.6
Li, D.7
García-Ojeda, M.E.8
Hinck, L.9
Forsberg, E.C.10
-
23
-
-
0344465840
-
Potential role of MCP-1 in endothelial cell tight junction 'opening': signaling via Rho and Rho kinase
-
Stamatovic S.M., Keep R.F., Kunkel S.L., Andjelkovic A.V. Potential role of MCP-1 in endothelial cell tight junction 'opening': signaling via Rho and Rho kinase. J. Cell Sci. 2003, 116:4615-4628.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 4615-4628
-
-
Stamatovic, S.M.1
Keep, R.F.2
Kunkel, S.L.3
Andjelkovic, A.V.4
-
24
-
-
0037418208
-
IL-1 is required for tumor invasiveness and angiogenesis
-
Voronov E., Shouval D.S., Krelin Y., Cagnano E., Benharroch D., Iwakura Y., Dinarello C.A., Apte R.N. IL-1 is required for tumor invasiveness and angiogenesis. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:2645-2650.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 2645-2650
-
-
Voronov, E.1
Shouval, D.S.2
Krelin, Y.3
Cagnano, E.4
Benharroch, D.5
Iwakura, Y.6
Dinarello, C.A.7
Apte, R.N.8
-
25
-
-
0026083903
-
Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma
-
Weidner N., Semple J.P., Welch W.R., Folkman J. Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N. Engl. J. Med. 1991, 324:1-8.
-
(1991)
N. Engl. J. Med.
, vol.324
, pp. 1-8
-
-
Weidner, N.1
Semple, J.P.2
Welch, W.R.3
Folkman, J.4
-
26
-
-
84891051959
-
Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia
-
Zhao H., Anand A.R., Ganju R.K. Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia. J. Immunol. 2014, 192:385-393.
-
(2014)
J. Immunol.
, vol.192
, pp. 385-393
-
-
Zhao, H.1
Anand, A.R.2
Ganju, R.K.3
-
27
-
-
84898476721
-
Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis
-
Zhou W., Fong M.Y., Min Y., Somlo G., Liu L., Palomares M.R., Yu Y., Chow A., O'Connor S.T., Chin A.R., et al. Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis. Cancer Cell 2014, 25:501-515.
-
(2014)
Cancer Cell
, vol.25
, pp. 501-515
-
-
Zhou, W.1
Fong, M.Y.2
Min, Y.3
Somlo, G.4
Liu, L.5
Palomares, M.R.6
Yu, Y.7
Chow, A.8
O'Connor, S.T.9
Chin, A.R.10
-
28
-
-
84870993821
-
Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability
-
Zhu W., London N.R., Gibson C.C., Davis C.T., Tong Z., Sorensen L.K., Shi D.S., Guo J., Smith M.C., Grossmann A.H., et al. Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability. Nature 2012, 492:252-255.
-
(2012)
Nature
, vol.492
, pp. 252-255
-
-
Zhu, W.1
London, N.R.2
Gibson, C.C.3
Davis, C.T.4
Tong, Z.5
Sorensen, L.K.6
Shi, D.S.7
Guo, J.8
Smith, M.C.9
Grossmann, A.H.10
|