메뉴 건너뛰기




Volumn 64, Issue 2, 2016, Pages 386-393

Patient-reported outcomes of elderly adults with chronic hepatitis C treated with interferon- and ribavirin-free regimens

Author keywords

chronic hepatitis C; CLDQ HCV; health related quality of life; LDV SOF; older adults; WPAI:SHP

Indexed keywords

LEDIPASVIR PLUS SOFOSBUVIR; PEGINTERFERON; RIBAVIRIN; SOFOSBUVIR; ANTIVIRUS AGENT; BENZIMIDAZOLE DERIVATIVE; FLUORENE DERIVATIVE; INTERFERON; LEDIPASVIR;

EID: 84958870076     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/jgs.13928     Document Type: Article
Times cited : (34)

References (40)
  • 1
    • 84894354149 scopus 로고    scopus 로고
    • Prevalence and estimation of hepatitis B and C infections in the WHO European Region: A review of data focusing on the countries outside the European Union and the European Free Trade Association
    • Hope VD, Eramova I, Capurro D, et al., Prevalence and estimation of hepatitis B and C infections in the WHO European Region: A review of data focusing on the countries outside the European Union and the European Free Trade Association. Epidemiol Infect 2014; 142: 270-286.
    • (2014) Epidemiol Infect , vol.142 , pp. 270-286
    • Hope, V.D.1    Eramova, I.2    Capurro, D.3
  • 2
    • 84876149257 scopus 로고    scopus 로고
    • Global epidemiology of hepatitis C virus infection: New estimates of age-specific antibody to HCV seroprevalence
    • Kharyriyyah MH, Groeger J, Flaxman AD, et al., Global epidemiology of hepatitis C virus infection: New estimates of age-specific antibody to HCV seroprevalence. Hepatol 2013; 57: 1333-1342.
    • (2013) Hepatol , vol.57 , pp. 1333-1342
    • Kharyriyyah, M.H.1    Groeger, J.2    Flaxman, A.D.3
  • 3
    • 75149163334 scopus 로고    scopus 로고
    • Aging of hepatitis C virus (HCV)-infected persons in the United States: A multiple cohort model of HCV prevalence and disease progression
    • Davis GL, Alter MJ, El-Serag H, et al., Aging of hepatitis C virus (HCV)-infected persons in the United States: A multiple cohort model of HCV prevalence and disease progression. Gastroenterol 2010; 138: 513-521.
    • (2010) Gastroenterol , vol.138 , pp. 513-521
    • Davis, G.L.1    Alter, M.J.2    El-Serag, H.3
  • 4
    • 84868212975 scopus 로고    scopus 로고
    • Impact of disease severity on healthcare costs in patients with chronic hepatitis C (CHC) virus infection
    • Gordon SC, Pockros PJ, Terrault NA, et al., Impact of disease severity on healthcare costs in patients with chronic hepatitis C (CHC) virus infection. Hepatology 2012; 56: 1651-1660.
    • (2012) Hepatology , vol.56 , pp. 1651-1660
    • Gordon, S.C.1    Pockros, P.J.2    Terrault, N.A.3
  • 5
    • 77949755595 scopus 로고    scopus 로고
    • Hepatitis C Virus-related chronic liver disease in elderly patients: An Italian cross-sectional study
    • Gramenzi A, Conti F, Felline F, et al., Hepatitis C Virus-related chronic liver disease in elderly patients: An Italian cross-sectional study. J Viral Hepat 2009; 17: 360-366.
    • (2009) J Viral Hepat , vol.17 , pp. 360-366
    • Gramenzi, A.1    Conti, F.2    Felline, F.3
  • 6
    • 84885180331 scopus 로고    scopus 로고
    • The impact of chronic hepatitis C on resource utilisation and in-patient mortality for Medicare beneficiaries between 2005 and 2010
    • Younossi ZM, Stepanova M, Mishra A, et al., The impact of chronic hepatitis C on resource utilisation and in-patient mortality for Medicare beneficiaries between 2005 and 2010. Aliment Pharmacol Ther 2013; 38: 1065-1075.
    • (2013) Aliment Pharmacol Ther , vol.38 , pp. 1065-1075
    • Younossi, Z.M.1    Stepanova, M.2    Mishra, A.3
  • 7
    • 0035133564 scopus 로고    scopus 로고
    • The effects of interferon alpha 2-b in combination with ribavirin and health related quality of life and productivity
    • McHutchison JG, Ware JE, Bayliss MS, et al., The effects of interferon alpha 2-b in combination with ribavirin and health related quality of life and productivity. J Hepatol 2001; 34: 140-147.
    • (2001) J Hepatol , vol.34 , pp. 140-147
    • McHutchison, J.G.1    Ware, J.E.2    Bayliss, M.S.3
  • 8
    • 84879113095 scopus 로고    scopus 로고
    • Chronic hepatitis C virus (HCV) disease burden and cost in the United States
    • Razavi H, Elkhoury AC, Elbasha E, et al., Chronic hepatitis C virus (HCV) disease burden and cost in the United States. Hepatology 2013; 57: 2164-2170.
    • (2013) Hepatology , vol.57 , pp. 2164-2170
    • Razavi, H.1    Elkhoury, A.C.2    Elbasha, E.3
  • 9
    • 0037387851 scopus 로고    scopus 로고
    • Projecting future complications of chronic hepatitis C in the United States
    • Davis GL, Albright JE, Cook SF, et al., Projecting future complications of chronic hepatitis C in the United States. Liver Transpl 2003; 9: 331-338.
    • (2003) Liver Transpl , vol.9 , pp. 331-338
    • Davis, G.L.1    Albright, J.E.2    Cook, S.F.3
  • 10
    • 33846209454 scopus 로고    scopus 로고
    • Factors influencing health-related quality of life in chronic liver disease
    • Sobhonslidsuk A, Silpakit C, Kongsakon R, et al., Factors influencing health-related quality of life in chronic liver disease. World J Gastroenterol 2006; 12: 7786-7791.
    • (2006) World J Gastroenterol , vol.12 , pp. 7786-7791
    • Sobhonslidsuk, A.1    Silpakit, C.2    Kongsakon, R.3
  • 12
    • 0036911895 scopus 로고    scopus 로고
    • Assessment of fatigue in patients with chronic hepatitis C using the Fatigue Impact Scale
    • Hassoun Z, Willems B, Deslauriers J, et al., Assessment of fatigue in patients with chronic hepatitis C using the Fatigue Impact Scale. Dig Dis Sci 2002; 47: 2674-2681.
    • (2002) Dig Dis Sci , vol.47 , pp. 2674-2681
    • Hassoun, Z.1    Willems, B.2    Deslauriers, J.3
  • 13
    • 34547912777 scopus 로고    scopus 로고
    • Fatigue and health-related quality of life (HRQL) in chronic hepatitis C virus infection
    • Kallman J, O'Neil MM, Larive B, et al., Fatigue and health-related quality of life (HRQL) in chronic hepatitis C virus infection. Dig Dis Sci 2007; 52: 2531-2539.
    • (2007) Dig Dis Sci , vol.52 , pp. 2531-2539
    • Kallman, J.1    O'Neil, M.M.2    Larive, B.3
  • 14
    • 84901628185 scopus 로고    scopus 로고
    • Multiple factors predict physical performance in people with chronic liver disease
    • Loria A, Doyle K, Weinstein AA, et al., Multiple factors predict physical performance in people with chronic liver disease. Am J Phys Med Rehabil. 2014; 93: 470-6.
    • (2014) Am J Phys Med Rehabil , vol.93 , pp. 470-476
    • Loria, A.1    Doyle, K.2    Weinstein, A.A.3
  • 15
    • 0035175607 scopus 로고    scopus 로고
    • Chronic liver disease and health-related quality of life
    • Younossi ZM,. Chronic liver disease and health-related quality of life. Gastroenterology 2001; 120: 305-307.
    • (2001) Gastroenterology , vol.120 , pp. 305-307
    • Younossi, Z.M.1
  • 16
    • 68249122450 scopus 로고    scopus 로고
    • Predictors of health-related quality of life in patients with chronic liver disease
    • Afendy A1, Kallman JB, Stepanova M, et al., Predictors of health-related quality of life in patients with chronic liver disease. Aliment Pharmacol Ther 2009; 30: 469-476.
    • (2009) Aliment Pharmacol Ther , vol.30 , pp. 469-476
    • Afendy, A.1    Kallman, J.B.2    Stepanova, M.3
  • 17
    • 77949950915 scopus 로고    scopus 로고
    • Psychological determinants of health-related quality of life in patients with chronic liver disease
    • Gutteling JJ, Duivenvoorden HJ, Busschbach JJ, et al., Psychological determinants of health-related quality of life in patients with chronic liver disease. Psychosomatics. 2010; 51: 157-165.
    • (2010) Psychosomatics. , vol.51 , pp. 157-165
    • Gutteling, J.J.1    Duivenvoorden, H.J.2    Busschbach, J.J.3
  • 18
    • 84867288022 scopus 로고    scopus 로고
    • Recommendations for the identification of chronic hepatitis C Virus infection among persons born during 1945-1965
    • Smith BD, Morgan RL, Beckett GA, et al., Recommendations for the identification of chronic hepatitis C Virus infection among persons born during 1945-1965. MMWR Recomm Rep 2012; 4: 1-32.
    • (2012) MMWR Recomm Rep , vol.4 , pp. 1-32
    • Smith, B.D.1    Morgan, R.L.2    Beckett, G.A.3
  • 19
    • 84870405295 scopus 로고    scopus 로고
    • Hepatitis C Virus testing of persons born during 1945-1965: Recommendations from the centers for disease control and prevention
    • Smith BD, Morgan RL, Beckett GA, et al., Hepatitis C Virus testing of persons born during 1945-1965: Recommendations from the centers for disease control and prevention. Ann Intern Med 2012; 157: 817-822.
    • (2012) Ann Intern Med , vol.157 , pp. 817-822
    • Smith, B.D.1    Morgan, R.L.2    Beckett, G.A.3
  • 20
    • 84877730954 scopus 로고    scopus 로고
    • Sofosbuvir for previously untreated chronic hepatitis C infection
    • Lawitz E, Mangia A, Wyles D, et al., Sofosbuvir for previously untreated chronic hepatitis C infection. N Engl J Med 2013; 368: 1878-1887.
    • (2013) N Engl J Med , vol.368 , pp. 1878-1887
    • Lawitz, E.1    Mangia, A.2    Wyles, D.3
  • 21
    • 84894068078 scopus 로고    scopus 로고
    • Impact of interferon free regimens on clinical and cost outcomes for chronic hepatitis C genotype 1 patients
    • Younossi ZM, Singer ME, Mir HM, et al., Impact of interferon free regimens on clinical and cost outcomes for chronic hepatitis C genotype 1 patients. J Hepatol 2014; 60: 530-537.
    • (2014) J Hepatol , vol.60 , pp. 530-537
    • Younossi, Z.M.1    Singer, M.E.2    Mir, H.M.3
  • 22
    • 84943230055 scopus 로고    scopus 로고
    • The changing landscape of hepatitis C virus therapy: Focus on interferon-free treatment
    • Lam BP, Jeffers T, Younoszai Z, Fazel Y, Younossi ZM,. The changing landscape of hepatitis C virus therapy: focus on interferon-free treatment. Therap Adv Gastroenterol. 2015; 8: 298-312.
    • (2015) Therap Adv Gastroenterol , vol.8 , pp. 298-312
    • Lam, B.P.1    Jeffers, T.2    Younoszai, Z.3    Fazel, Y.4    Younossi, Z.M.5
  • 23
    • 84877739274 scopus 로고    scopus 로고
    • Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options
    • POSITRON Study; FUSION Study.
    • Jacobson IM, Gordon SC, Kowdley KV, et al.,; POSITRON Study; FUSION Study. Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options. N Engl J Med 2013; 368: 1867-1877.
    • (2013) N Engl J Med , vol.368 , pp. 1867-1877
    • Jacobson, I.M.1    Gordon, S.C.2    Kowdley, K.V.3
  • 24
    • 84900339263 scopus 로고    scopus 로고
    • Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection
    • ION-1 Investigators.
    • Afdhal N, Zeuzem S, Kwo P, et al.,; ION-1 Investigators. Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection. N Engl J Med 2014; 370: 1889-1898.
    • (2014) N Engl J Med , vol.370 , pp. 1889-1898
    • Afdhal, N.1    Zeuzem, S.2    Kwo, P.3
  • 25
    • 84898669547 scopus 로고    scopus 로고
    • Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection
    • ION-2 Investigators.
    • Afdhal N, Reddy KR, Nelson DR, et al.,; ION-2 Investigators. Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection. N Engl J Med 2014; 370: 1483-1493.
    • (2014) N Engl J Med , vol.370 , pp. 1483-1493
    • Afdhal, N.1    Reddy, K.R.2    Nelson, D.R.3
  • 26
    • 84900992889 scopus 로고    scopus 로고
    • Sofosbuvir and ribavirin in HCV genotypes 2 and 3
    • VALENCE Investigators.
    • Zeuzem S, Dusheiko GM, Salupere R, et al.,; VALENCE Investigators. Sofosbuvir and ribavirin in HCV genotypes 2 and 3. N Engl J Med 2014; 370: 1993-2001.
    • (2014) N Engl J Med , vol.370 , pp. 1993-2001
    • Zeuzem, S.1    Dusheiko, G.M.2    Salupere, R.3
  • 27
    • 84900326091 scopus 로고    scopus 로고
    • Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis
    • ION-3 Investigators.
    • Kowdley KV, Gordon SC, Reddy KR, et al.,; ION-3 Investigators. Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis. N Engl J Med 2014; 370: 1879-1888.
    • (2014) N Engl J Med , vol.370 , pp. 1879-1888
    • Kowdley, K.V.1    Gordon, S.C.2    Reddy, K.R.3
  • 28
    • 84892751187 scopus 로고    scopus 로고
    • Sofosbuvir+Ribavirin for 12 or 24 Weeks for Patients with HCV Genotype 2 or 3: The VALENCE trial
    • Zeuzem S, Dusheiko G, Salupere R, et al., Sofosbuvir+Ribavirin for 12 or 24 Weeks for Patients with HCV Genotype 2 or 3: The VALENCE trial. Hepatology 2013; 58: 1085.
    • (2013) Hepatology , vol.58 , pp. 1085
    • Zeuzem, S.1    Dusheiko, G.2    Salupere, R.3
  • 29
    • 0035185005 scopus 로고    scopus 로고
    • Interpreting SF-36 summary health measures: A response
    • Ware JE, Kosinski M,. Interpreting SF-36 summary health measures: A response. Qual Life Res 2001; 10: 405-413.
    • (2001) Qual Life Res , vol.10 , pp. 405-413
    • Ware, J.E.1    Kosinski, M.2
  • 30
    • 1542323315 scopus 로고    scopus 로고
    • The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: Validation of version 4 of the core questionnaire
    • Webster K, Odom L, Peterman A, et al., The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: Validation of version 4 of the core questionnaire. Qual Life Res 1999; 8: 604.
    • (1999) Qual Life Res , vol.8 , pp. 604
    • Webster, K.1    Odom, L.2    Peterman, A.3
  • 31
    • 0032864860 scopus 로고    scopus 로고
    • Development of a disease specific questionnaire to measure health related quality of life in patients with chronic liver disease
    • Younossi ZM, Guyatt G, Kiwi M, et al., Development of a disease specific questionnaire to measure health related quality of life in patients with chronic liver disease. Gut 1999; 45: 295-300.
    • (1999) Gut , vol.45 , pp. 295-300
    • Younossi, Z.M.1    Guyatt, G.2    Kiwi, M.3
  • 32
    • 0027693577 scopus 로고
    • The validity and reproducibility of a work productivity and activity impairment instrument
    • Reilly MC, Zbrozek AS, Dukes EM,. The validity and reproducibility of a work productivity and activity impairment instrument. Pharmacoeconomics 1993; 4: 353-365.
    • (1993) Pharmacoeconomics , vol.4 , pp. 353-365
    • Reilly, M.C.1    Zbrozek, A.S.2    Dukes, E.M.3
  • 33
    • 84906281539 scopus 로고    scopus 로고
    • Patients' preferences and health utility assessment with SF-6D and EQ-5D in patients with chronic hepatitis C treated with sofosbuvir regimens
    • Stepanova M, Nader F, Cure S, et al., Patients' preferences and health utility assessment with SF-6D and EQ-5D in patients with chronic hepatitis C treated with sofosbuvir regimens. Aliment Pharmacol Ther. 2014; 40: 676-85.
    • (2014) Aliment Pharmacol Ther , vol.40 , pp. 676-685
    • Stepanova, M.1    Nader, F.2    Cure, S.3
  • 34
    • 84904381202 scopus 로고    scopus 로고
    • Effects of sofosbuvir-based treatment, with and without interferon, on outcome and productivity of patients with chronic hepatitis C
    • Younossi ZM, Stepanova M, Henry L, et al., Effects of sofosbuvir-based treatment, with and without interferon, on outcome and productivity of patients with chronic hepatitis C. Clin Gastroenterol Hepatol. 2014; 12: 1349-5.
    • (2014) Clin Gastroenterol Hepatol , vol.12 , pp. 1349-1355
    • Younossi, Z.M.1    Stepanova, M.2    Henry, L.3
  • 35
    • 84901439598 scopus 로고    scopus 로고
    • Patient-reported outcomes in chronic hepatitis C patients with cirrhosis treated with sofosbuvir-containing regimens
    • Younossi ZM, Stepanova M, Nader F, et al., Patient-reported outcomes in chronic hepatitis C patients with cirrhosis treated with sofosbuvir-containing regimens. Hepatology 2014; 59: 2161-2169.
    • (2014) Hepatology , vol.59 , pp. 2161-2169
    • Younossi, Z.M.1    Stepanova, M.2    Nader, F.3
  • 36
    • 84904730054 scopus 로고    scopus 로고
    • Patient-reported outcomes assessment in chronic hepatitis C treated with sofosbuvir and ribavirin: The VALENCE Study
    • Younossi ZM, Stepanova M, Zeuzem S, et al., Patient-reported outcomes assessment in chronic hepatitis C treated with sofosbuvir and ribavirin: The VALENCE Study. J Hepatol. 2014; 61: 228-34.
    • (2014) J Hepatol , vol.61 , pp. 228-234
    • Younossi, Z.M.1    Stepanova, M.2    Zeuzem, S.3
  • 37
    • 84929607189 scopus 로고    scopus 로고
    • Treatment with ledipasvir and sofosbuvir improves patient-reported outcomes: Results from the ION-1, -2, and -3 clinical trials
    • Younossi ZM, Stepanova M, Marcellin P, et al., Treatment with ledipasvir and sofosbuvir improves patient-reported outcomes: Results from the ION-1, -2, and -3 clinical trials. Hepatology. 2015; 61: 1798-808.
    • (2015) Hepatology , vol.61 , pp. 1798-1808
    • Younossi, Z.M.1    Stepanova, M.2    Marcellin, P.3
  • 38
    • 84925028249 scopus 로고    scopus 로고
    • Resource utilization and survival among Medicare patients with advanced liver disease
    • Otgonsuren M, Henry L, Hunt S, et al., Resource utilization and survival among Medicare patients with advanced liver disease. Dig Dis Sci 2015; 60: 320-332.
    • (2015) Dig Dis Sci , vol.60 , pp. 320-332
    • Otgonsuren, M.1    Henry, L.2    Hunt, S.3
  • 39
    • 74849128654 scopus 로고    scopus 로고
    • The healthcare burden imposed by liver disease in aging Baby Boomers
    • Davis GL, Roberts WL,. The healthcare burden imposed by liver disease in aging Baby Boomers. Curr Gastroenterol Rep 2010; 12: 1-6.
    • (2010) Curr Gastroenterol Rep , vol.12 , pp. 1-6
    • Davis, G.L.1    Roberts, W.L.2
  • 40
    • 2542465496 scopus 로고    scopus 로고
    • Obtained from the world wide web at. Last accessed on 5 Dec 2015.
    • Food and Drug Administration- Hepatitis B and C treatments. Obtained from the world wide web at http://www.fda.gov/ForPatients/Illness/HepatitisBC/ucm408658.htm. Last accessed on 5 Dec 2015.
    • Food and Drug Administration- Hepatitis B and C Treatments


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.