Small-molecule inhibitors prevent the genotoxic and protumoural effects induced by colibactin-producing bacteria

Gut

Volumn 65, Issue 2, 2016, Pages 278-285

  Cougnoux, Antony ^a   Delmas, Julien ^a,b   Gibold, Lucie ^a,b   Faïs, Tiphanie ^a   Romagnoli, Chiara ^c   Robin, Frederic ^a,b   Cuevas Ramos, Gabriel ^d   Oswald, Eric ^d,e,f   Darfeuille Michaud, Arlette ^a   Prati, Fabio ^c   Dalmasso, Guillaume ^a   Bonnet, Richard ^a,b  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b UNIVERSITY HOSPITAL OF CLERMONT FERRAND   (France)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^d UNIVERSITÉ DE TOULOUSE   (France)

^e UNIVERSITÉ PAUL SABATIER   (France)

^f CHU PURPAN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BACTERIAL TOXIN; BORONIC ACID; COLIBACTIN; PROTECTIVE AGENT; UNCLASSIFIED DRUG; BORONIC ACID DERIVATIVE; CALCIUM BINDING PROTEIN; LIGAND; MUTAGENIC AGENT; PEPTIDE; POLYKETIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BACTERIUM IDENTIFICATION; CARCINOGENESIS; CELL PROLIFERATION; COLORECTAL CANCER; COMPLEX FORMATION; CRYSTAL STRUCTURE; DISEASE ACTIVITY; DISEASE CONTROL; DNA DAMAGE; DRUG DETERMINATION; DRUG MECHANISM; DRUG STRUCTURE; ESCHERICHIA COLI; GENOTOXICITY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INTESTINE EPITHELIUM CELL; MOLECULAR DOCKING; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BAGG ALBINO MOUSE; COLORECTAL NEOPLASMS; DRUG EFFECTS; METABOLISM; MICROBIOLOGY; PHYSIOLOGY;

ANIMALS; BORONIC ACIDS; CALCIUM-BINDING PROTEINS; COLORECTAL NEOPLASMS; DNA DAMAGE; ESCHERICHIA COLI; LIGANDS; MICE; MICE, INBRED BALB C; MUTAGENS; PEPTIDES; POLYKETIDES;

EID: 84958840355     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2014-307241     Document Type: Article

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