메뉴 건너뛰기




Volumn 63, Issue 5, 2014, Pages 761-770

Colonic mucosa-associated diffusely adherent afaC+ Escherichia coli expressing lpfA and pks are increased in inflammatory bowel disease and colon cancer

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; VASCULOTROPIN;

EID: 84897964236     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2013-304739     Document Type: Article
Times cited : (176)

References (56)
  • 1
    • 79960863193 scopus 로고    scopus 로고
    • Bacteria in the pathogenesis of inflammatory bowel disease
    • Flanagan P, Campbell BJ, Rhodes JM. Bacteria in the pathogenesis of inflammatory bowel disease. Biochem Soc Trans 2011;39:1067-72.
    • (2011) Biochem Soc Trans , vol.39 , pp. 1067-1072
    • Flanagan, P.1    Campbell, B.J.2    Rhodes, J.M.3
  • 3
    • 33751556362 scopus 로고    scopus 로고
    • Abnormal microbiota composition in the ileocolonic mucosa of Crohn's disease patients as revealed by polymerase chain reaction-denaturing gradient gel electrophoresis
    • DOI 10.1097/01.mib.0000235828.09305.0c, PII 0005472520061200000007
    • Martinez-Medina M, Aldeguer X, Gonzalez-Huix F, et al. Abnormal microbiota composition in the ileocolonic mucosa of Crohn's disease patients as revealed by PCR-denaturing gradient gel electrophoresis. Infl amm Bowel Dis 2006;12:1136-45. (Pubitemid 44847471)
    • (2006) Inflammatory Bowel Diseases , vol.12 , Issue.12 , pp. 1136-1145
    • Martinez-Medina, M.1    Aldeguer, X.2    Gonzalez-Huix, F.3    Acero, D.4    Garcia-Gil, L.J.5
  • 4
    • 67649509224 scopus 로고    scopus 로고
    • Molecular diversity of Escherichia coli in the human gut: New ecological evidence supporting the role of adherent-invasive E. Coli (AIEC) in Crohn's disease
    • Martinez-Medina M, Aldeguer X, Lopez-Siles M, et al. Molecular diversity of Escherichia coli in the human gut: new ecological evidence supporting the role of adherent-invasive E. coli (AIEC) in Crohn's disease. Inflamm Bowel Dis 2009;15:872-82.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 872-882
    • Martinez-Medina, M.1    Aldeguer, X.2    Lopez-Siles, M.3
  • 6
    • 18944382323 scopus 로고    scopus 로고
    • Molecular characterization of rectal mucosa-associated bacterial flora in infl ammatory bowel disease
    • Mylonaki M, Rayment NB, Rampton DS, et al. Molecular characterization of rectal mucosa-associated bacterial flora in infl ammatory bowel disease. Inflamm Bowel Dis 2005;11:481-7.
    • (2005) Inflamm Bowel Dis , vol.11 , pp. 481-487
    • Mylonaki, M.1    Rayment, N.B.2    Rampton, D.S.3
  • 7
    • 66249129571 scopus 로고    scopus 로고
    • Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease
    • Willing B, Halfvarson J, Dicksved J, et al. Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohn's disease. Inflamm Bowel Dis 2009;15:653-60.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 653-660
    • Willing, B.1    Halfvarson, J.2    Dicksved, J.3
  • 10
    • 34247500287 scopus 로고    scopus 로고
    • High prevalence of Escherichia coli belonging to the B2+D phylogenetic group in inflammatory bowel disease
    • DOI 10.1136/gut.2006.099796
    • Kotlowski R, Bernstein CN, Sepheri S, et al. High prevalence of Escherichia coli belonging to the B2 and D phylogenetic groups in infl ammatory bowel disease. Gut 2007;56:669-75. (Pubitemid 46662933)
    • (2007) Gut , vol.56 , Issue.5 , pp. 669-675
    • Kotlowski, R.1    Bernstein, C.N.2    Sepehri, S.3    Krause, D.O.4
  • 11
    • 34250375140 scopus 로고    scopus 로고
    • Microbial diversity of inflamed and noninflamed gut biopsy tissues in inflammatory bowel disease
    • DOI 10.1002/ibd.20101
    • Sepehri S, Kotlowski R, Bernstein CN, et al. Microbial diversity of inflamed and non-inflamed gut biopsy tissues in inflammatory bowel disease. Inflamm Bowel Dis 2007;13:675-83. (Pubitemid 46909981)
    • (2007) Inflammatory Bowel Diseases , vol.13 , Issue.6 , pp. 675-683
    • Sepehri, S.1    Kotlowski, R.2    Bernstein, C.N.3    Krause, D.O.4
  • 12
    • 0034873344 scopus 로고    scopus 로고
    • Adherent invasive Escherichia coli strains from patients with Crohn's disease survive and replicate within macrophages without inducing host cell death
    • DOI 10.1128/IAI.69.9.5529-5537.2001
    • Glasser AL, Boudeau J, Barnich N, et al. Adherent invasive Escherichia coli strains from patients with Crohn's disease survive and replicate within macrophages without inducing host cell death. Infect Immun 2001;69:5529-37. (Pubitemid 32786488)
    • (2001) Infection and Immunity , vol.69 , Issue.9 , pp. 5529-5537
    • Glasser, A.-L.1    Boudeau, J.2    Barnich, N.3    Perruchot, M.-H.4    Colombel, J.-F.5    Darfeuille-Michaud, A.6
  • 16
    • 77958603351 scopus 로고    scopus 로고
    • Complete genome sequence of Crohn's disease-associated adherent-invasive E. Coli strain LF82
    • Miquel S, Peyretaillade E, Claret L, et al. Complete genome sequence of Crohn's disease-associated adherent-invasive E. coli strain LF82. PLoS ONE 2010;5:e12714.
    • (2010) PLoS ONE , vol.5
    • Miquel, S.1    Peyretaillade, E.2    Claret, L.3
  • 17
    • 12844262949 scopus 로고    scopus 로고
    • HtrA stress protein is involved in intramacrophagic replication of adherent and invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease
    • DOI 10.1128/IAI.73.2.712-721.2005
    • Bringer MA, Barnich N, Glasser AL, et al. HtrA stress protein is involved in intramacrophagic replication of adherent, invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease. Infect Immun 2005;73:712-21. (Pubitemid 40165726)
    • (2005) Infection and Immunity , vol.73 , Issue.2 , pp. 712-721
    • Bringer, M.-A.1    Barnich, N.2    Glasser, A.-L.3    Bardot, O.4    Darfeuille-Michaud, A.5
  • 18
    • 34347368520 scopus 로고    scopus 로고
    • The oxidoreductase DsbA plays a key role in the ability of the Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 to resist macrophage killing
    • DOI 10.1128/JB.00233-07
    • Bringer MA, Rolhion N, Glasser AL, et al. The oxidoreductase DsbA plays a key role in the ability of the Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 to resist macrophage killing. J Bacteriol 2007;189:4860-71. (Pubitemid 47025598)
    • (2007) Journal of Bacteriology , vol.189 , Issue.13 , pp. 4860-4871
    • Bringer, M.-A.1    Rolhion, N.2    Glasser, A.-L.3    Darfeuille-Michaud, A.4
  • 19
    • 79952230127 scopus 로고    scopus 로고
    • Crohn disease-associated adherent-invasive E. Coli bacteria target mouse and human Peyer's patches via long polar fimbriae
    • Chassaing B, Rolhion N, Vallee A, et al. Crohn disease-associated adherent-invasive E. coli bacteria target mouse and human Peyer's patches via long polar fimbriae. J Clin Invest 2011;121:966-75.
    • (2011) J Clin Invest , vol.121 , pp. 966-975
    • Chassaing, B.1    Rolhion, N.2    Vallee, A.3
  • 20
    • 17444409988 scopus 로고    scopus 로고
    • Pathogenesis of Afa/Dr diffusely adhering Escherichia coli
    • DOI 10.1128/CMR.18.2.264-292.2005
    • Servin AL. Pathogenesis of Afa/Dr diffusely-adhering Escherichia coli. Clin Microbiol Rev 2005;18:264-92. (Pubitemid 40548294)
    • (2005) Clinical Microbiology Reviews , vol.18 , Issue.2 , pp. 264-292
    • Servin, A.L.1
  • 21
    • 0036258843 scopus 로고    scopus 로고
    • Adhesion and entry of uropathogenic Escherichia coli
    • DOI 10.1046/j.1462-5822.2002.00193.x
    • Mulvey MA. Adhesion and entry of uropathogenic Escherichia coli. Cell Microbiol 2002;4:257-71. (Pubitemid 34567594)
    • (2002) Cellular Microbiology , vol.4 , Issue.5 , pp. 257-271
    • Mulvey, M.A.1
  • 22
    • 84867192879 scopus 로고    scopus 로고
    • Intestinal inflammation targets cancer-inducing activity of the microbiota
    • Arthur JC, Perez-Chanona E, Mühlbauer M, et al. Intestinal inflammation targets cancer-inducing activity of the microbiota. Science 2012;338:120-3.
    • (2012) Science , vol.338 , pp. 120-123
    • Arthur, J.C.1    Perez-Chanona, E.2    Mühlbauer, M.3
  • 23
    • 84874007506 scopus 로고    scopus 로고
    • High prevalence of mucosa-associated E. Coli producing cyclomodulin and genotoxin in colon cancer
    • Buc E, Dubois D, Sauvanet P, et al. High prevalence of mucosa-associated E. coli producing cyclomodulin and genotoxin in colon cancer. PLoS ONE 2013;8:e56964.
    • (2013) PLoS ONE , vol.8
    • Buc, E.1    Dubois, D.2    Sauvanet, P.3
  • 25
    • 0024413254 scopus 로고
    • Molecular characterization of a fimbrial adhesin, F1845, mediating diffuse adherence of diarrhea-associated Escherichia coli to HEp-2 cells
    • Bilge SS, Clausen CR, Lau W, et al. Molecular characterization of a fimbrial adhesin, F1845, mediating diffuse adherence of diarrhea-associated Escherichia coli to HEp-2 cells. J Bacteriol 1989;171:4281-9. (Pubitemid 19190321)
    • (1989) Journal of Bacteriology , vol.171 , Issue.8 , pp. 4281-4289
    • Bilge, S.S.1    Clausen, C.R.2    Lau, W.3    Moseley, S.L.4
  • 28
    • 77957201539 scopus 로고    scopus 로고
    • Translocation of Crohn's disease Escherichia coli across M-cells: Contrasting effects of soluble plant fibres and emulsifiers
    • Roberts CL, Keita AV, Duncan SH, et al. Translocation of Crohn's disease Escherichia coli across M-cells: contrasting effects of soluble plant fibres and emulsifiers. Gut 2010;59:1331-9.
    • (2010) Gut , vol.59 , pp. 1331-1339
    • Roberts, C.L.1    Keita, A.V.2    Duncan, S.H.3
  • 29
    • 77954295386 scopus 로고    scopus 로고
    • HIF-1alpha mediates the induction of IL-8 and VEGF expression on infection with Afa/Dr diffusely adhering E. Coli and promotes EMT-like behaviour
    • Cane G, Ginouves A, Marchetti S, et al. HIF-1alpha mediates the induction of IL-8 and VEGF expression on infection with Afa/Dr diffusely adhering E. coli and promotes EMT-like behaviour. Cell Microbiol 2010;12:640-53.
    • (2010) Cell Microbiol , vol.12 , pp. 640-653
    • Cane, G.1    Ginouves, A.2    Marchetti, S.3
  • 30
    • 78650407055 scopus 로고    scopus 로고
    • VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer
    • Waldner MJ, Wirtz S, Jefremow A, et al. VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer. J Exp Med 2010;207:2855-68.
    • (2010) J Exp Med , vol.207 , pp. 2855-2868
    • Waldner, M.J.1    Wirtz, S.2    Jefremow, A.3
  • 31
    • 0022262779 scopus 로고
    • Genetic organization of the afimbrial adhesin operon and nucleotide sequence from a uropathogenic Escherichia coli gene encoding an afimbrial adhesin
    • Labigne-Roussel A, Schmidt MA, Walz W, et al. Genetic organization of the afimbrial adhesin operon and nucleotide sequence from a uropathogenic Escherichia coli gene encoding an afimbrial adhesin. J Bacteriol 1985;162:1285-92. (Pubitemid 15012296)
    • (1985) Journal of Bacteriology , vol.162 , Issue.3 , pp. 1285-1292
    • Labigne-Roussel, A.1    Schmidt, M.A.2    Walz, W.3    Falkow, S.4
  • 32
    • 33644820670 scopus 로고    scopus 로고
    • Diffusely adherent Escherichia coli strains expressing Afa/Dr adhesins (Afa/Dr DAEC): Hitherto unrecognized pathogens
    • DOI 10.1111/j.1574-6968.2006.00144.x
    • Le Bouguenec C, Servin AL. Diffusely adherent Escherichia coli strains expressing Afa/Dr adhesins (Afa/Dr DAEC): hitherto unrecognized pathogens. FEMS Microbiol Letts 2006;256:185-94. (Pubitemid 43356788)
    • (2006) FEMS Microbiology Letters , vol.256 , Issue.2 , pp. 185-194
    • Le, B.C.1    Servin, A.L.2
  • 33
    • 0032792638 scopus 로고    scopus 로고
    • M cells as ports of entry for enteroinvasive pathogens: Mechanisms of interaction, consequences for the disease process
    • DOI 10.1006/smim.1999.0175
    • Sansonetti PJ, Phalipon A. M cells as ports of entry for enteroinvasive pathogens: mechanisms of interaction, consequences for the disease process. Semin Immunol 1999;11:193-203. (Pubitemid 29358578)
    • (1999) Seminars in Immunology , vol.11 , Issue.3 , pp. 193-203
    • Sansonetti, P.J.1    Phalipon, A.2
  • 34
    • 70449653428 scopus 로고    scopus 로고
    • Uptake through glycoprotein 2 of FimH(+) bacteria by M-cells initiates mucosal immune response
    • Hase K, Kawano K, Nochi T, et al. Uptake through glycoprotein 2 of FimH(+) bacteria by M-cells initiates mucosal immune response. Nature 2009;462:226-30.
    • (2009) Nature , vol.462 , pp. 226-230
    • Hase, K.1    Kawano, K.2    Nochi, T.3
  • 35
    • 0029948461 scopus 로고    scopus 로고
    • Pathogenesis of aphthoid ulcers in Crohn's disease: Correlative findings by magnifying colonoscopy, electron microscopy, and immunohistochemistry
    • Fujimura Y, Kamoi R, Iida M. Pathogenesis of aphthoid ulcers in Crohn's disease: correlative findings by magnifying colonoscopy, electron microscopy, and immunohistochemistry. Gut 1996;38:724-32. (Pubitemid 26167481)
    • (1996) Gut , vol.38 , Issue.5 , pp. 724-732
    • Fujimura, Y.1    Kamoi, R.2    Iida, M.3
  • 36
    • 84864307060 scopus 로고    scopus 로고
    • Characterization of lymphoid follicles with red ring signs as first manifestation of early Crohn's disease by conventional histopathology and confocal laser endomicroscopy
    • Krauss A, Agaimy A, Neumann H, et al. Characterization of lymphoid follicles with red ring signs as first manifestation of early Crohn's disease by conventional histopathology and confocal laser endomicroscopy. Int J Clin Exp Pathol 2012;5:411-21.
    • (2012) Int J Clin Exp Pathol , vol.5 , pp. 411-421
    • Krauss, A.1    Agaimy, A.2    Neumann, H.3
  • 37
    • 0033849561 scopus 로고    scopus 로고
    • Early vascular changes in Crohn's disease: An endoscopic fluorescence study
    • Maunory V, Mordon S, Geboes K, et al. Early vascular changes in Crohn's disease: an endoscopic fluorescence study. Endoscopy 2000;32:700-5.
    • (2000) Endoscopy , vol.32 , pp. 700-705
    • Maunory, V.1    Mordon, S.2    Geboes, K.3
  • 38
    • 77955046881 scopus 로고    scopus 로고
    • Abnormal CEACAM6 expression in Crohn disease patients favors gut colonization and inflammation by adherent-invasive E. Coli
    • Barnich N, Darfeuille-Michaud A. Abnormal CEACAM6 expression in Crohn disease patients favors gut colonization and inflammation by adherent-invasive E. coli. Virulence 2010;1:281-2.
    • (2010) Virulence , vol.1 , pp. 281-282
    • Barnich, N.1    Darfeuille-Michaud, A.2
  • 40
    • 0030024046 scopus 로고    scopus 로고
    • Differential expression of complement proteins and regulatory decay accelerating factor in relation to differentiation of cultured human colon adenocarcinoma cell lines
    • Bernet-Camard MF, Coconnier MH, Hudault S, et al. Differential expression of complement proteins and regulatory decay accelerating factor in relation to differentiation of cultured human colon adenocarcinoma cell lines. Gut 1996;38:248-53. (Pubitemid 26046822)
    • (1996) Gut , vol.38 , Issue.2 , pp. 248-253
    • Bernet-Camard, M.-F.1    Coconnier, M.-H.2    Hudault, S.3    Servin, A.L.4
  • 41
    • 51949106120 scopus 로고    scopus 로고
    • Escherichia coli DraE adhesin-associated bacterial internalization by epithelial cells is promoted independently by decay-accelerating factor and carcinoembryonic antigen-related cell adhesion molecule binding and does not require the DraD invasin
    • Korotkova N, Yarova-Yarovaya Y, Tchesnokova V, et al. Escherichia coli DraE adhesin-associated bacterial internalization by epithelial cells is promoted independently by decay-accelerating factor and carcinoembryonic antigen-related cell adhesion molecule binding and does not require the DraD invasin. Infect Immun 2008;76:3869-80.
    • (2008) Infect Immun , vol.76 , pp. 3869-3880
    • Korotkova, N.1    Yarova-Yarovaya, Y.2    Tchesnokova, V.3
  • 42
    • 0030991257 scopus 로고    scopus 로고
    • Dr fimbriae operon of uropathogenic Escherichia coli mediate microtubule-dependent invasion to the HeLa epithelial cell line
    • Goluszko P, Popov V, Selvarangan R, et al. Dr fimbriae operon of uropathogenic Escherichia coli mediate microtubule-dependent invasion to the HeLa epithelial cell-line. J Infect Dis 1997;176:158-67. (Pubitemid 27272864)
    • (1997) Journal of Infectious Diseases , vol.176 , Issue.1 , pp. 158-167
    • Goluszko, P.1    Popov, V.2    Selvarangan, R.3    Nowicki, S.4    Pham, T.5    Nowicki, B.J.6
  • 43
    • 0034075292 scopus 로고    scopus 로고
    • Recruitment of CD55 and CD66e brush border-associated glycosylphosphatidylinositol-anchored proteins by members of the Afa/Dr diffusely adhering family of Escherichia coli that infect the human polarized intestinal Caco-2/TC7 cells
    • DOI 10.1128/IAI.68.6.3554-3563.2000
    • Guignot J, Peiffer I, Bernet-Camard MF, et al. Recruitment of CD55 and CD66e brush border-associated glycosylphosphatidylinositol-anchored proteins by members of the Afa/Dr diffusely adhering family of Escherichia coli that infect the human polarized intestinal Caco-2/TC7 cells. Infect Immun 2000;68:3554-63. (Pubitemid 30340457)
    • (2000) Infection and Immunity , vol.68 , Issue.6 , pp. 3554-3563
    • Guignot, J.1    Peiffer, I.2    Bernet-Camard, M.-F.3    Lublin, D.M.4    Carnoy, C.5    Moseley, S.L.6    Servin, A.L.7
  • 44
    • 0031925365 scopus 로고    scopus 로고
    • Expression of cell membrane complement regulatory glycoproteins along the normal and diseased human gastrointestinal tract
    • Berstad AE, Brandtzaeg P. Expression of cell membrane complement regulatory glycoproteins along the normal and diseased human gastrointestinal tract. Gut 1998;42:522-9. (Pubitemid 28186570)
    • (1998) Gut , vol.42 , Issue.4 , pp. 522-529
    • Berstad, A.E.1    Brandtzaeg, P.2
  • 45
    • 0026442537 scopus 로고
    • Decay-accelerating factor (DAF, CD55) in normal colorectal mucosa, adenomas and carcinomas
    • Koretz K, Bruderlein S, Henne C, et al. Decay-accelerating factor (DAF, CD55) in normal colorectal mucosa, adenomas and carcinomas. Br J Cancer 1992;66:810-14.
    • (1992) Br J Cancer , vol.66 , pp. 810-814
    • Koretz, K.1    Bruderlein, S.2    Henne, C.3
  • 46
    • 0345268672 scopus 로고    scopus 로고
    • Afa/Dr diffusely adhering Escherichia coli infection in T84 cell monolayers induces increased neutrophil transepithelial migration, which in turn promotes cytokine-dependent upregulation of decay-accelerating factor (CD55), the receptor for Afa/Dr adhesins
    • DOI 10.1128/IAI.71.4.1774-1783.2003
    • Betis F, Brest P, Hofman V, et al. Afa/Dr diffusely adhering Escherichia coli infection in T84 cell monolayers induces increased neutrophil transepithelial migration, which in turn promotes cytokine-dependent upregulation of decay-accelerating factor (CD55), the receptor for Afa/Dr adhesins. Infect Immun 2003;71:1774-83. (Pubitemid 36368706)
    • (2003) Infection and Immunity , vol.71 , Issue.4 , pp. 1774-1783
    • Betis, F.1    Brest, P.2    Hofman, V.3    Guignot, J.4    Kansau, I.5    Rossi, B.6    Servin, A.7    Hofman, P.8
  • 47
    • 4644313098 scopus 로고    scopus 로고
    • Increased rate of apoptosis and diminished phagocytic ability of human neutrophils infected with Afa/Dr diffusely adhering Escherichia coli strains
    • DOI 10.1128/IAI.72.10.5741-5749.2004
    • Brest P, Betis F, Cuburu N, et al. Increased rate of apoptosis and diminished phagocytic ability of human neutrophils infected with Afa/Dr diffusely adhering Escherichia coli strains. Infect Immun 2004;72:5741-9. (Pubitemid 39303684)
    • (2004) Infection and Immunity , vol.72 , Issue.10 , pp. 5741-5749
    • Brest, P.1    Betis, F.2    Cuburu, N.3    Selva, E.4    Herrant, M.5    Servin, A.6    Auberger, P.7    Hofman, P.8
  • 48
    • 0028859007 scopus 로고
    • Nonlethal adherence to human neutrophils mediated by Dr antigen-specific adhesins of Escherichia coli
    • Johnson JR, Skubitz KM, Nowicki BJ, et al. Nonlethal adherence to human neutrophils mediated by Dr antigen-specific adhesins of Escherichia coli. Infect Immun 1995;63:309-16.
    • (1995) Infect Immun , vol.63 , pp. 309-316
    • Johnson, J.R.1    Skubitz, K.M.2    Nowicki, B.J.3
  • 49
    • 72549109556 scopus 로고    scopus 로고
    • Identification of GP2, the major zymogen granule membrane glycoprotein, as the autoantigen of pancreatic antibodies in Crohn's disease
    • Roggenbuck D, Hausdorf G, Martinez-Gamboa L, et al. Identification of GP2, the major zymogen granule membrane glycoprotein, as the autoantigen of pancreatic antibodies in Crohn's disease. Gut 2009;58:1620-28.
    • (2009) Gut , vol.58 , pp. 1620-1628
    • Roggenbuck, D.1    Hausdorf, G.2    Martinez-Gamboa, L.3
  • 50
    • 79958799781 scopus 로고    scopus 로고
    • Characterization of Escherichia coli isolated from gut biopsies of newly diagnosed patients with inflammatory bowel disease
    • Sepehri S, Khafipour E, Bernstein CN, et al. Characterization of Escherichia coli isolated from gut biopsies of newly diagnosed patients with inflammatory bowel disease. Inflamm Bowel Dis 2011;17:1451-63.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1451-1463
    • Sepehri, S.1    Khafipour, E.2    Bernstein, C.N.3
  • 51
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY, et al. Epithelial-mesenchymal transitions in development and disease. Cell 2009;139:871-90.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3
  • 52
    • 59249092718 scopus 로고    scopus 로고
    • Evidence for a role of epithelial mesenchymal transition during pathogenesis of fistulae in Crohn's disease
    • Bataille F, Rohrmeier C, Bates R, et al. Evidence for a role of epithelial mesenchymal transition during pathogenesis of fistulae in Crohn's disease. Inflamm Bowel Dis 2008;14:1514-27.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 1514-1527
    • Bataille, F.1    Rohrmeier, C.2    Bates, R.3
  • 53
    • 77953769774 scopus 로고    scopus 로고
    • Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis
    • Flier SN, Tanjore H, Kokkotou EG, et al. Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis. J Biol Chem 2010;285:20202-12.
    • (2010) J Biol Chem , vol.285 , pp. 20202-20212
    • Flier, S.N.1    Tanjore, H.2    Kokkotou, E.G.3
  • 54
    • 0036138686 scopus 로고    scopus 로고
    • Inflammation and colorectal cancer: IBD-associated and sporadic cancer compared
    • DOI 10.1016/S1471-4914(01)02194-3, PII S1471491401021943
    • Rhodes JM, Campbell BJ. Inflammation and colorectal cancer: IBD-associated and sporadic cancer compared. Trends Mol Med 2002;8:10-16. (Pubitemid 34044673)
    • (2002) Trends in Molecular Medicine , vol.8 , Issue.1 , pp. 10-16
    • Rhodes, J.M.1    Campbell, B.J.2
  • 55
    • 4043088499 scopus 로고    scopus 로고
    • IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • DOI 10.1016/j.cell.2004.07.013, PII S0092867404006713
    • Greten FR, Eckmann L, Greten TF, et al. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 2004;118:285-96. (Pubitemid 39061110)
    • (2004) Cell , vol.118 , Issue.3 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3    Park, J.M.4    Li, Z.-W.5    Egan, L.J.6    Kagnoff, M.F.7    Karin, M.8
  • 56
    • 34447296425 scopus 로고    scopus 로고
    • Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88
    • DOI 10.1126/science.1140488
    • Rakoff-Nahoum S, Medzhitov R. Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science 2007;317:124-7. (Pubitemid 47056471)
    • (2007) Science , vol.317 , Issue.5834 , pp. 124-127
    • Rakoff-Nahoum, S.1    Medzhitov, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.