Ursolic acid-loaded chitosan nanoparticles induce potent anti-angiogenesis in tumor

Applied Microbiology and Biotechnology

Volumn 100, Issue 15, 2016, Pages 6643-6652

  Jin, Hua ^a,b   Pi, Jiang ^a   Yang, Fen ^a   Wu, Chaomin ^c   Cheng, Xueli ^d   Bai, Haihua ^d   Huang, Dan ^b   Jiang, Jinhuan ^a   Cai, Jiye ^a   Chen, Zheng W ^b  

^a MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Macao)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c FUDAN UNIVERSITY   (China)

^d SAE Technologies Development (Dongguan) Co Ltd   (China)

Author keywords

Anti angiogenesis; Anti tumor activity; Chicken chorioallantoic membrane model; H22 xenografts mouse model; Ursolic acid loaded chitosan nanoparticles

Indexed keywords

ANIMALS; CARBOXYLIC ACIDS; CELL DEATH; CELL MEMBRANES; CHITOSAN; ENDOTHELIAL CELLS; MITOCHONDRIA; NANOPARTICLES; TUMORS;

ANGIOGENESIS; ANTI-TUMOR ACTIVITIES; CHICKEN CHORIOALLANTOIC MEMBRANES; CHITOSAN NANOPARTICLES; MOUSE MODELS;

DRUG DELIVERY;

ALPHA TUBULIN; CHITOSAN NANOPARTICLE; F ACTIN; FIBROBLAST GROWTH FACTOR 2; LACTATE DEHYDROGENASE; RHODAMINE B; URSOLIC ACID; ANGIOGENESIS INHIBITOR; CHITOSAN; DRUG CARRIER; NANOPARTICLE; TRITERPENE;

APOPTOSIS; BIOGENIC MATERIAL; BIOTECHNOLOGY; CANCER; CELLS AND CELL COMPONENTS; DISEASE TREATMENT; DRUG DEVELOPMENT; NANOPARTICLE; ORGANIC COMPOUND; OXYGEN; POULTRY; RODENT; TUMOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER MODEL; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CHICK EMBRYO; CHICKEN; CHORIOALLANTOIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG MEGADOSE; DRUG POTENCY; EMBRYO; ENZYME RELEASE; FEMALE; FLOW CYTOMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC50; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIVER CELL CARCINOMA; LYSOSOME; LYSOSOME MEMBRANE; MIGRATION INHIBITION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; MOUSE MODEL; MTT ASSAY; NONHUMAN; TUMOR XENOGRAFT; UMBILICAL VEIN ENDOTHELIAL CELL; ZETA POTENTIAL; ANIMAL; BAGG ALBINO MOUSE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; METABOLISM; NEOVASCULARIZATION, PATHOLOGIC; TUMOR CELL LINE; VASCULARIZATION; WOUND HEALING;

ANGIOGENESIS INHIBITORS; ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHICK EMBRYO; CHITOSAN; CHORIOALLANTOIC MEMBRANE; DRUG CARRIERS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED BALB C; MITOCHONDRIA; NANOPARTICLES; NEOVASCULARIZATION, PATHOLOGIC; TRITERPENES; WOUND HEALING; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84958773511     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-016-7360-8     Document Type: Article

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