Recessive mutations in the cancer gene Ataxia Telangiectasia Mutated (ATM), at a locus previously associated with metformin response, cause dysglycaemia and insulin resistance

Diabetic Medicine

Volumn 33, Issue 3, 2016, Pages 371-375

  Connelly, P J ^a   Smith, N ^a   Chadwick, R ^b   Exley, A R ^b   Shneerson, J M ^b   Pearson, Ewan R ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b PAPWORTH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; GLUCOSE; INSULIN; METFORMIN; ATM PROTEIN, HUMAN; GLUCOSE BLOOD LEVEL; PHARMACOLOGICAL BIOMARKER;

ADULT; ARTICLE; ATAXIA TELANGIECTASIA; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DYSGLYCEMIA; FEMALE; GENE LOCUS; GENE MUTATION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; HUMAN; INSULIN BLOOD LEVEL; INSULIN METABOLISM; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; ORAL GLUCOSE TOLERANCE TEST; TUMOR GENE; CASE CONTROL STUDY; DISORDERS OF CARBOHYDRATE METABOLISM; DRUG EFFECTS; GENETICS; GLUCOSE TOLERANCE TEST; METABOLISM; RECESSIVE GENE; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ATAXIA TELANGIECTASIA MUTATED PROTEINS; BIOMARKERS, PHARMACOLOGICAL; BLOOD GLUCOSE; CASE-CONTROL STUDIES; FEMALE; GENES, NEOPLASM; GENES, RECESSIVE; GENETIC LOCI; GLUCOSE METABOLISM DISORDERS; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN RESISTANCE; MALE; METABOLIC NETWORKS AND PATHWAYS; METFORMIN; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84958757097     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/dme.13037     Document Type: Article

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