-
1
-
-
84919999219
-
Management of hyperglycemia in type 2 diabetes, 2015: A patient-centered approach: Update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes
-
Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycemia in type 2 diabetes, 2015: A patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care. 2015;38:140-149
-
(2015)
Diabetes Care
, vol.38
, pp. 140-149
-
-
Inzucchi, S.E.1
Bergenstal, R.M.2
Buse, J.B.3
-
2
-
-
84877757399
-
The place of GLP-1-based therapy in diabetes management: Differences between DPP-4 inhibitors and GLP-1 receptor agonists
-
Eckerle Mize DL, Salehi M. The place of GLP-1-based therapy in diabetes management: differences between DPP-4 inhibitors and GLP-1 receptor agonists. Curr Diab Rep. 2013;13:307-318
-
(2013)
Curr Diab Rep.
, vol.13
, pp. 307-318
-
-
Eckerle Mize, D.L.1
Salehi, M.2
-
3
-
-
80052362968
-
Role of sodiumglucose cotransporter 2 (SGLT-2) inhibitors in the treatment of type 2 diabetes
-
Abdul-Ghani MA, Norton L, Defronzo RA. Role of sodiumglucose cotransporter 2 (SGLT-2) inhibitors in the treatment of type 2 diabetes. Endocr Rev. 2011;32:515-531
-
(2011)
Endocr Rev.
, vol.32
, pp. 515-531
-
-
Abdul-Ghani, M.A.1
Norton, L.2
Defronzo, R.A.3
-
4
-
-
34147189738
-
The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single dose administration in type 2 diabetic patients
-
Balas B, Baig MR, Watson C, et al. The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single dose administration in type 2 diabetic patients. J Clin Endocrinol Metab. 2007;92:1249-1255
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 1249-1255
-
-
Balas, B.1
Baig, M.R.2
Watson, C.3
-
5
-
-
84937971687
-
The efficacy and safety of DPP4 inhibitors compared to sulfonylureas as add-on therapy to metformin in patients with type 2 diabetes: A systematic review and meta-analysis
-
Mishriky BM, Cummings DM, Tanenberg RJ. The efficacy and safety of DPP4 inhibitors compared to sulfonylureas as add-on therapy to metformin in patients with type 2 diabetes: A systematic review and meta-analysis. Diabetes Res Clin Pract. 2015;109(2):378-388
-
(2015)
Diabetes Res Clin Pract.
, vol.109
, Issue.2
, pp. 378-388
-
-
Mishriky, B.M.1
Cummings, D.M.2
Tanenberg, R.J.3
-
6
-
-
84939229165
-
Sitagliptin in type 2 diabetes mellitus: Efficacy after five years of therapy
-
Derosa G, D'Angelo A, Maffioli P. Sitagliptin in type 2 diabetes mellitus: efficacy after five years of therapy. Pharmacol Res. 2015;100:127-134
-
(2015)
Pharmacol Res.
, vol.100
, pp. 127-134
-
-
Derosa, G.1
D'Angelo, A.2
Maffioli, P.3
-
7
-
-
84929964372
-
Cost effectiveness of dipeptidyl peptidase-4 inhibitors for type 2 diabetes
-
Geng J, Yu H, Mao Y, et al. Cost effectiveness of dipeptidyl peptidase-4 inhibitors for type 2 diabetes. Pharmacoeconomics. 2015;33(6):581-597
-
(2015)
Pharmacoeconomics
, vol.33
, Issue.6
, pp. 581-597
-
-
Geng, J.1
Yu, H.2
Mao, Y.3
-
8
-
-
84923791994
-
Pharmacodynamics, efficacy and safety of sodium-glucose co-transporter type 2 (SGLT2) inhibitors for the treatment of type 2 diabetes mellitus
-
Scheen AJ. Pharmacodynamics, efficacy and safety of sodium-glucose co-transporter type 2 (SGLT2) inhibitors for the treatment of type 2 diabetes mellitus. Drugs. 2015;75:33-59
-
(2015)
Drugs
, vol.75
, pp. 33-59
-
-
Scheen, A.J.1
-
9
-
-
84901198078
-
Blood pressure effects of sodium-glucose co-transport2 (SGLT2) inhibitors
-
Oliva RV, Bakris GL. Blood pressure effects of sodium-glucose co-transport2 (SGLT2) inhibitors. J Am Soc Hypertens. 2014;8(5):330-339
-
(2014)
J Am Soc Hypertens
, vol.8
, Issue.5
, pp. 330-339
-
-
Oliva, R.V.1
Bakris, G.L.2
-
10
-
-
84928426587
-
Longterm glycaemic response and tolerability of dapagliflozin versus a sulphonylurea as add-on therapy to metformin in patients with type 2 diabetes: 4-year data
-
Del Prato S, Nauck M, Durán-Garcia S, et al., et al. Longterm glycaemic response and tolerability of dapagliflozin versus a sulphonylurea as add-on therapy to metformin in patients with type 2 diabetes: 4-year data. Diabetes Obes Metab. 2015;17(6):581-590
-
(2015)
Diabetes Obes Metab
, vol.17
, Issue.6
, pp. 581-590
-
-
Del Prato, S.1
Nauck, M.2
Durán-Garcia, S.3
-
11
-
-
64649104158
-
Banting Lecture,From the triumvirate to the ominous octet: A new paradigm for the treatment of type 2 diabetes mellitus
-
DeFronzo RA. Banting Lecture. From the triumvirate to the ominous octet: A new paradigm for the treatment of type 2 diabetes mellitus. Diabetes. 2009;58:773-795
-
(2009)
Diabetes
, vol.58
, pp. 773-795
-
-
DeFronzo, R.A.1
-
12
-
-
84893827104
-
Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production
-
Merovci A, Solis-Herrera C, Daniele G, et al. Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production. J Clin Invest. 2014;124:509-514
-
(2014)
J Clin Invest.
, vol.124
, pp. 509-514
-
-
Merovci, A.1
Solis-Herrera, C.2
Daniele, G.3
-
13
-
-
84893872877
-
Metabolic response to sodium-glucose co-transporter 2 inhibition in type 2 diabetic patients
-
Ferrannini E, Muscelli E, Frascerra S, et al. Metabolic response to sodium-glucose co-transporter 2 inhibition in type 2 diabetic patients. J Clin Invest. 2014;124:499-508
-
(2014)
J Clin Invest.
, vol.124
, pp. 499-508
-
-
Ferrannini, E.1
Muscelli, E.2
Frascerra, S.3
-
14
-
-
84896816933
-
Changes in insulin sensitivity and insulin secretion with the sodium glucose cotransporter 2 inhibitor dapagliflozin
-
Mudaliar S, Henry RR, Boden G, et al. Changes in insulin sensitivity and insulin secretion with the sodium glucose cotransporter 2 inhibitor dapagliflozin. Diabetes Technol Ther. 2014;16(3):137-144
-
(2014)
Diabetes Technol Ther.
, vol.16
, Issue.3
, pp. 137-144
-
-
Mudaliar, S.1
Henry, R.R.2
Boden, G.3
-
15
-
-
0029976176
-
Effects of ingested fructose and infused glucagon on endogenous glucose production in obese NIDDM patients, obese non-diabetic subjects, and healthy subjects
-
Paquot N, Schneiter P, Jequier E, et al. Effects of ingested fructose and infused glucagon on endogenous glucose production in obese NIDDM patients, obese non-diabetic subjects, and healthy subjects. Diabetologia. 1996;39:580-586
-
(1996)
Diabetologia
, vol.39
, pp. 580-586
-
-
Paquot, N.1
Schneiter, P.2
Jequier, E.3
-
16
-
-
84917742055
-
Postprandial dynamics of plasma glucose, insulin and glucagon in patients with type 2 diabetes treated with saxagliptin plus dapagliflozin add-on to metformin therapy
-
Hansen L, Iqbal N, Ekholm E, et al. Postprandial dynamics of plasma glucose, insulin and glucagon in patients with type 2 diabetes treated with saxagliptin plus dapagliflozin add-on to metformin therapy. Endocr Pract. 2014;20:1187-1197
-
(2014)
Endocr Pract.
, vol.20
, pp. 1187-1197
-
-
Hansen, L.1
Iqbal, N.2
Ekholm, E.3
-
17
-
-
6944221886
-
Stimulatory short-term effects of free fatty acids on glucagon secretion at low to normal glucose concentrations
-
Bollheimer LC, Landauer HC, Troll S, et al. Stimulatory short-term effects of free fatty acids on glucagon secretion at low to normal glucose concentrations. Metabolism. 2004;53:1443-1448
-
(2004)
Metabolism
, vol.53
, pp. 1443-1448
-
-
Bollheimer, L.C.1
Landauer, H.C.2
Troll, S.3
-
18
-
-
84937763347
-
Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion
-
Bonner C, Kerr-Conte J, Gmyr V, et al. Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion. Nat Med. 2015;21:512-517
-
(2015)
Nat Med.
, vol.21
, pp. 512-517
-
-
Bonner, C.1
Kerr-Conte, J.2
Gmyr, V.3
-
19
-
-
84941183428
-
Perspective: SGLT2 inhibitors may predispose to ketoacidosis
-
[Epub ahead of print]
-
Taylor SI, Blau JE, Rother KI. Perspective: SGLT2 inhibitors may predispose to ketoacidosis. J Clin Endocrinol Metab. 2015;18:jc20151884. [Epub ahead of print]
-
(2015)
J Clin Endocrinol Metab
, vol.18
, pp. jc20151884
-
-
Taylor, S.I.1
Blau, J.E.2
Rother, K.I.3
-
20
-
-
84981335309
-
Sodium glucose co-transporter-2 inhibitors and euglycemic ketoacidosis: Wisdom of hindsight
-
Singh AK. Sodium glucose co-transporter-2 inhibitors and euglycemic ketoacidosis: wisdom of hindsight. Indian J Endocr Metab. 2015;19(6):722-730
-
(2015)
Indian J Endocr Metab
, vol.19
, Issue.6
, pp. 722-730
-
-
Singh, A.K.1
-
21
-
-
84944800184
-
Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes
-
[Epub ahead of print]
-
Zinman B, Wanner C, Lachin JM, et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. NEJM. 2015; [Epub ahead of print]. DOI:10.1056/ NEJMoa1504720
-
(2015)
NEJM
-
-
Zinman, B.1
Wanner, C.2
Lachin, J.M.3
-
22
-
-
33846006173
-
The incretin system: Glucagon like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
-
Drucker DJ, Nauck MA. The incretin system: glucagon like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet. 2006;368:1696-1705
-
(2006)
Lancet
, vol.368
, pp. 1696-1705
-
-
Drucker, D.J.1
Nauck, M.A.2
-
23
-
-
84951906012
-
Energy balance after sodium-glucose cotransporter 2 inhibition
-
Ferrannini G, Hach T, Crowe S, et al. Energy balance after sodium-glucose cotransporter 2 inhibition. Diabetes Care. 2015;38:1730-1735
-
(2015)
Diabetes Care
, vol.38
, pp. 1730-1735
-
-
Ferrannini, G.1
Hach, T.2
Crowe, S.3
-
24
-
-
84869141311
-
Sitagliptin reduces hyperglycemia and increases satiety hormone secretion more effectively when used with a novel polysaccharide in obese zucker rats
-
Reimer RA, Grover GJ, Koetzner L, et al. Sitagliptin reduces hyperglycemia and increases satiety hormone secretion more effectively when used with a novel polysaccharide in obese zucker rats. J Nutr. 2012;142 (10):1812-1820
-
(2012)
J Nutr.
, vol.142
, Issue.10
, pp. 1812-1820
-
-
Reimer, R.A.1
Grover, G.J.2
Koetzner, L.3
-
25
-
-
84906982768
-
The DPP-IV inhibitor linagliptin and GLP-1 induce synergistic effects on body weight loss and appetite suppression in the dietinduced obese rat
-
Hansen HH, Hansen G, Paulsen S, et al. The DPP-IV inhibitor linagliptin and GLP-1 induce synergistic effects on body weight loss and appetite suppression in the dietinduced obese rat. Eur J Pharmacol. 2014;741:254-263
-
(2014)
Eur J Pharmacol.
, vol.741
, pp. 254-263
-
-
Hansen, H.H.1
Hansen, G.2
Paulsen, S.3
-
26
-
-
78649715079
-
Lack of pharmacokinetic interaction between dapagliflozin, a novel sodium-glucose transporter 2 inhibitor, and metformin, pioglitazone, glimepiride or sitagliptin in healthy subjects
-
Kasichayanula S, Liu X, Shyu WC, et al. Lack of pharmacokinetic interaction between dapagliflozin, a novel sodium-glucose transporter 2 inhibitor, and metformin, pioglitazone, glimepiride or sitagliptin in healthy subjects. Diabetes Obes Metab. 2011;13(1):47-54
-
(2011)
Diabetes Obes Metab
, vol.13
, Issue.1
, pp. 47-54
-
-
Kasichayanula, S.1
Liu, X.2
Shyu, W.C.3
-
27
-
-
84872111344
-
Pharmacokinetics of empagliflozin, a sodium glucose cotransporter-2 (SGLT-2) inhibitor, coadministered with sitagliptin in healthy volunteers
-
Brand T, Macha S, Mattheus M, et al. Pharmacokinetics of empagliflozin, a sodium glucose cotransporter-2 (SGLT-2) inhibitor, coadministered with sitagliptin in healthy volunteers. Adv Ther. 2012;29(10):889-899
-
(2012)
Adv Ther.
, vol.29
, Issue.10
, pp. 889-899
-
-
Brand, T.1
Macha, S.2
Mattheus, M.3
-
28
-
-
84872418644
-
A randomized, open-label, crossover study to evaluate the pharmacokinetics of empagliflozin and linagliptin after coadministration in healthy male volunteers
-
Friedrich C, Metzmann K, Rose P, et al. A randomized, open-label, crossover study to evaluate the pharmacokinetics of empagliflozin and linagliptin after coadministration in healthy male volunteers. Clin Ther. 2013;35(1): A33-42
-
(2013)
Clin Ther.
, vol.35
, Issue.1
, pp. A33-42
-
-
Friedrich, C.1
Metzmann, K.2
Rose, P.3
-
29
-
-
84866540801
-
Effects of combining linagliptin treatment with BI-38335, a novel SGLT2 inhibitor, on pancreatic islet function and inflammation in db/db mice
-
Chen L, Klein T, Leung PS. Effects of combining linagliptin treatment with BI-38335, a novel SGLT2 inhibitor, on pancreatic islet function and inflammation in db/db mice. Curr Mol Med. 2012;12(8):995-1004
-
(2012)
Curr Mol Med.
, vol.12
, Issue.8
, pp. 995-1004
-
-
Chen, L.1
Klein, T.2
Leung, P.S.3
-
30
-
-
84865576863
-
Renal and cardiac effects of DPP-4 inhibitors-from preclinical development to clinical research
-
Hocher B, Reichetzeder C, Alter ML. Renal and cardiac effects of DPP-4 inhibitors-from preclinical development to clinical research. Kidney Blood Press Res. 2012;36:65-84
-
(2012)
Kidney Blood Press Res.
, vol.36
, pp. 65-84
-
-
Hocher, B.1
Reichetzeder, C.2
Alter, M.L.3
-
31
-
-
84906043294
-
The effects of GLP-1 analogues, DPP-4 inhibitors and SGLT2 inhibitors on the renal system
-
Schernthaner G, Mogensen CE, Schernthaner GH. The effects of GLP-1 analogues, DPP-4 inhibitors and SGLT2 inhibitors on the renal system. Diabetes Vasc Dis Res. 2014;11:306-323
-
(2014)
Diabetes Vasc Dis Res.
, vol.11
, pp. 306-323
-
-
Schernthaner, G.1
Mogensen, C.E.2
Schernthaner, G.H.3
-
32
-
-
84896701131
-
Dapagliflozin is effective as add-on therapy to sitagliptin with or without metformin: A 24-week, multicenter, randomized, double-blind, placebo-controlled study objective
-
Jabbour SA, Hardy E, Sugg J, et al. Dapagliflozin is effective as add-on therapy to sitagliptin with or without metformin: A 24-week, multicenter, randomized, double-blind, placebo-controlled study objective. Diabetes Care. 2014;37:740-750
-
(2014)
Diabetes Care
, vol.37
, pp. 740-750
-
-
Jabbour, S.A.1
Hardy, E.2
Sugg, J.3
-
33
-
-
84928201032
-
Dual add-on therapy in type 2 diabetes poorly controlled with metformin monotherapy: A randomized double-blind trial of saxagliptin plus dapagliflozin addition versus single addition of saxagliptin or dapagliflozin to metformin
-
Rosenstock J, Hansen L, Zee P, et al. Dual add-on therapy in type 2 diabetes poorly controlled with metformin monotherapy: A randomized double-blind trial of saxagliptin plus dapagliflozin addition versus single addition of saxagliptin or dapagliflozin to metformin. Diabetes Care. 2015;38:376-383
-
(2015)
Diabetes Care
, vol.38
, pp. 376-383
-
-
Rosenstock, J.1
Hansen, L.2
Zee, P.3
-
34
-
-
84962349319
-
Randomized, double-blind trial of triple therapy with saxagliptin addon to dapagliflozin plus metformin in patients with type 2 diabetes
-
Matthaei S, Catrinoiu D, Celinski A, et al. Randomized, double-blind trial of triple therapy with saxagliptin addon to dapagliflozin plus metformin in patients with type 2 diabetes. Diabetes Care. 2015;38:2018-2024
-
(2015)
Diabetes Care
, vol.38
, pp. 2018-2024
-
-
Matthaei, S.1
Catrinoiu, D.2
Celinski, A.3
-
35
-
-
84958650333
-
Randomized, doubleblind, phase 3 trial of triple therapy with dapagliflozin add-on to saxagliptin plus metformin in type 2 diabetes
-
Mathieu C, Ranetti AE, Li D, et al. Randomized, doubleblind, phase 3 trial of triple therapy with dapagliflozin add-on to saxagliptin plus metformin in type 2 diabetes. Diabetes Care. 2015;38:2009-2017
-
(2015)
Diabetes Care
, vol.38
, pp. 2009-2017
-
-
Mathieu, C.1
Ranetti, A.E.2
Li, D.3
-
36
-
-
84928199102
-
Initial combination of empagliflozin and linagliptin in subjects with type 2 diabetes
-
Lewin A, DeFronzo RA, Patel S, et al. Initial combination of empagliflozin and linagliptin in subjects with type 2 diabetes. Diabetes Care. 2015;38(3):394-402
-
(2015)
Diabetes Care
, vol.38
, Issue.3
, pp. 394-402
-
-
Lewin, A.1
DeFronzo, R.A.2
Patel, S.3
-
37
-
-
84928176749
-
Combination of empagliflozin and linagliptin as second-line therapy in subjects with type 2 diabetes inadequately controlled on metformin
-
DeFronzo RA, Lewin A, Patel S, et al. Combination of empagliflozin and linagliptin as second-line therapy in subjects with type 2 diabetes inadequately controlled on metformin. Diabetes Care. 2015;38:384-393
-
(2015)
Diabetes Care
, vol.38
, pp. 384-393
-
-
DeFronzo, R.A.1
Lewin, A.2
Patel, S.3
-
38
-
-
84981205804
-
Canagliflozin reduces both HbA1c and body weight in patients with type 2 diabetes on background dipeptidyl peptidase-4 inhibitors or glucagon-like peptide-1 agonists
-
Stockholm, Sweden
-
Woo V, Wysham C, Matheiu Cet al; Canagliflozin reduces both HbA1c and body weight in patients with type 2 diabetes on background dipeptidyl peptidase-4 inhibitors or glucagon-like peptide-1 agonists. European Association of Study in Diabetes Meeting, Stockholm, Sweden; 2015: OP-31: P-186
-
(2015)
European Association of Study in Diabetes Meeting
, pp. OP31-P186
-
-
Woo, V.1
Wysham, C.2
Cetal, M.3
-
39
-
-
84896478747
-
Long-term safety and efficacy of tofogliflozin, a selective inhibitor of sodiumglucose co-transporter 2, as monotherapy or in combination with other oral anti-diabetic agents in Japanese patients with type 2 diabetes mellitus: Multicenter, open-label, randomized controlled trials
-
Tanijawa Y, Kaku K, Araki E, et al. Long-term safety and efficacy of tofogliflozin, a selective inhibitor of sodiumglucose co-transporter 2, as monotherapy or in combination with other oral anti-diabetic agents in Japanese patients with type 2 diabetes mellitus: multicenter, open-label, randomized controlled trials. Expert Opin Pharmacol . 2014;15(6):749-766
-
(2014)
Expert Opin Pharmacol
, vol.15
, Issue.6
, pp. 749-766
-
-
Tanijawa, Y.1
Kaku, K.2
Araki, E.3
-
40
-
-
84933675778
-
Efficacy and safety of luseogliflozin added to various oral antidiabetic drugs in Japanese patients with type 2 diabetes mellitus
-
Seino Y, Inagaki N, Haneda M, et al Efficacy and safety of luseogliflozin added to various oral antidiabetic drugs in Japanese patients with type 2 diabetes mellitus. J Diabetes Invest. 2015;6:443-453
-
(2015)
J Diabetes Invest
, vol.6
, pp. 443-453
-
-
Seino, Y.1
Inagaki, N.2
Haneda, M.3
-
41
-
-
53749091595
-
10-year follow-up of intensive glucose control in type 2 diabetes
-
Holman RR, Paul SK, Bethel MA, et al 10-year follow-up of intensive glucose control in type 2 diabetes. N Engl J Med. 2008;359:1577-1589
-
(2008)
N Engl J Med
, vol.359
, pp. 1577-1589
-
-
Holman, R.R.1
Paul, S.K.2
Bethel, M.A.3
-
42
-
-
84940101393
-
Where does combination therapy with an SGLT2 inhibitor plus a DPP-4 inhibitor fit in the management of type 2 diabetes
-
Abdul-Ghani M. Where does combination therapy with an SGLT2 inhibitor plus a DPP-4 inhibitor fit in the management of type 2 diabetes? Diabetes Care. 2015;38:373-375
-
(2015)
Diabetes Care
, vol.38
, pp. 373-375
-
-
Abdul-Ghani, M.1
-
43
-
-
84931957338
-
How attractive is the combination of a sodium glucose co-transporter 2 inhibitor with a dipeptidyl peptidase 4 inhibitor in the treatment of type 2 diabetes
-
Schernthaner G, Schernthaner-Reiter MH. How attractive is the combination of a sodium glucose co-transporter 2 inhibitor with a dipeptidyl peptidase 4 inhibitor in the treatment of type 2 diabetes? Diabetes Obes Metabol. 2015;17:613-615
-
(2015)
Diabetes Obes Metabol
, vol.17
, pp. 613-615
-
-
Schernthaner, G.1
Schernthaner-Reiter, M.H.2
-
44
-
-
84943799774
-
The impact of chronic liraglutide therapy on glucagon secretion in type 2 diabetes: Insight from the LIBRA trial
-
Kramer CK, Zinman B, Choi H, et al. The impact of chronic liraglutide therapy on glucagon secretion in type 2 diabetes: Insight from the LIBRA trial. J Clin Endocrinol Metab. 2015;100(10):3702-3709.
-
(2015)
J Clin Endocrinol Metab
, vol.100
, Issue.10
, pp. 3702-3709
-
-
Kramer, C.K.1
Zinman, B.2
Choi, H.3
|