메뉴 건너뛰기




Volumn 16, Issue 3, 2014, Pages 137-144

Changes in insulin sensitivity and insulin secretion with the sodium glucose cotransporter 2 inhibitor dapagliflozin

Author keywords

[No Author keywords available]

Indexed keywords

DAPAGLIFLOZIN; GLUCOSE; GLYCOSYLATED HEMOGLOBIN; INSULIN; INSULIN SECRETAGOGUE; METFORMIN; PLACEBO; UNCLASSIFIED DRUG; 2-(3-(4-ETHOXYBENZYL)-4-CHLOROPHENYL)-6-HYDROXYMETHYLTETRAHYDRO-2H-PYRAN-3,4,5-TRIOL; ANTIDIABETIC AGENT; C PEPTIDE; CREATININE; GLUCOSE BLOOD LEVEL; GLUCOSIDE; HEMOGLOBIN A1C PROTEIN, HUMAN; SODIUM GLUCOSE COTRANSPORTER 2;

EID: 84896816933     PISSN: 15209156     EISSN: 15578593     Source Type: Journal    
DOI: 10.1089/dia.2013.0167     Document Type: Article
Times cited : (91)

References (18)
  • 1
    • 4143151942 scopus 로고    scopus 로고
    • Pathogenesis of type 2 diabetes mellitus
    • ix
    • DeFronzo RA: Pathogenesis of type 2 diabetes mellitus. Med Clin North Am 2004;88:787-835, ix.
    • (2004) Med Clin North Am , vol.88 , pp. 787-835
    • Defronzo, R.A.1
  • 3
    • 0029880428 scopus 로고    scopus 로고
    • Effects of prolonged glucose infusion on insulin secretion, clearance, and action in normal subjects
    • Boden G, Ruiz J, Kim CJ, Chen X: Effects of prolonged glucose infusion on insulin secretion, clearance, and action in normal subjects. Am J Physiol 1996;270:E251-E258.
    • (1996) Am J Physiol , vol.270
    • Boden, G.1    Ruiz, J.2    Kim, C.J.3    Chen, X.4
  • 4
    • 70549113397 scopus 로고    scopus 로고
    • Role of glucotoxicity and lipotoxicity in the pathophysiology of Type 2 diabetes mellitus and emerging treatment strategies
    • Del Prato S: Role of glucotoxicity and lipotoxicity in the pathophysiology of Type 2 diabetes mellitus and emerging treatment strategies. Diabet Med 2009;26:1185-1192.
    • (2009) Diabet Med , vol.26 , pp. 1185-1192
    • Del Prato, S.1
  • 5
    • 0038825044 scopus 로고    scopus 로고
    • Glucotoxicity and beta-cell failure in type 2 diabetes mellitus
    • Kaiser N, Leibowitz G, Nesher R: Glucotoxicity and beta-cell failure in type 2 diabetes mellitus. J Pediatr Endocrinol Metab 2003;16:5-22.
    • (2003) J Pediatr Endocrinol Metab , vol.16 , pp. 5-22
    • Kaiser, N.1    Leibowitz, G.2    Nesher, R.3
  • 6
    • 0023571397 scopus 로고
    • Effect of chronic hyperglycemia on in vivo insulin secretion in partially pancreatectomized rats
    • Rossetti L, Shulman GI, Zawalich W, DeFronzo RA: Effect of chronic hyperglycemia on in vivo insulin secretion in partially pancreatectomized rats. J Clin Invest 1987;80:1037-1044.
    • (1987) J Clin Invest , vol.80 , pp. 1037-1044
    • Rossetti, L.1    Shulman, G.I.2    Zawalich, W.3    Defronzo, R.A.4
  • 7
    • 0023275573 scopus 로고
    • Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats
    • Rossetti L, Smith D, Shulman GI, Papachristou D, DeFronzo RA: Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. J Clin Invest 1987;79:1510-1515.
    • (1987) J Clin Invest , vol.79 , pp. 1510-1515
    • Rossetti, L.1    Smith, D.2    Shulman, G.I.3    Papachristou, D.4    Defronzo, R.A.5
  • 8
    • 84875139337 scopus 로고    scopus 로고
    • Chronic dapagliflozin treatment reduces elevated hepatic glucose production and enhances pancreatic insulin content in male ZDF rats [abstract 1031-P]
    • Zinker B, Ma X, Liu H, Cai C, Ponticiello R, Zalaznick J, Washburn W, Whaley J: Chronic dapagliflozin treatment reduces elevated hepatic glucose production and enhances pancreatic insulin content in male ZDF rats [abstract 1031-P]. Diabetes 2011;60(Suppl 1):A283.
    • (2011) Diabetes , vol.60 , Issue.SUPPL. 1
    • Zinker, B.1    Ma, X.2    Liu, H.3    Cai, C.4    Ponticiello, R.5    Zalaznick, J.6    Washburn, W.7    Whaley, J.8
  • 9
    • 77953857048 scopus 로고    scopus 로고
    • Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: A randomised, double-blind, placebo-controlled trial
    • Bailey CJ, Gross JL, Pieters A, Bastien A, List JF: Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial. Lancet 2010;375:2223-2233.
    • (2010) Lancet , vol.375 , pp. 2223-2233
    • Bailey, C.J.1    Gross, J.L.2    Pieters, A.3    Bastien, A.4    List, J.F.5
  • 10
    • 0036726473 scopus 로고    scopus 로고
    • Intravenous glargine and regular insulin have similar effects on endogenous glucose output and peripheral activation/deactivation kinetic profiles
    • Mudaliar S, Mohideen P, Deutsch R, Ciaraldi TP, Armstrong D, Kim B, Sha X, Henry RR: Intravenous glargine and regular insulin have similar effects on endogenous glucose output and peripheral activation/deactivation kinetic profiles. Diabetes Care 2002;25:1597-1602.
    • (2002) Diabetes Care , vol.25 , pp. 1597-1602
    • Mudaliar, S.1    Mohideen, P.2    Deutsch, R.3    Ciaraldi, T.P.4    Armstrong, D.5    Kim, B.6    Sha, X.7    Henry, R.R.8
  • 12
    • 0019810028 scopus 로고
    • Physiologic evaluation of factors controlling glucose tolerance in man: Measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose
    • Bergman RN, Phillips LS, Cobelli C: Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose. J Clin Invest 1981;68: 1456-1467.
    • (1981) J Clin Invest , vol.68 , pp. 1456-1467
    • Bergman, R.N.1    Phillips, L.S.2    Cobelli, C.3
  • 13
    • 0347624611 scopus 로고    scopus 로고
    • MINMOD Millennium: A computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test
    • Boston RC, Stefanovski D, Moate PJ, Sumner AE, Watanabe RM, Bergman RN: MINMOD Millennium: a computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test. Diabetes Technol Ther 2003; 5:1003-1015.
    • (2003) Diabetes Technol Ther , vol.5 , pp. 1003-1015
    • Boston, R.C.1    Stefanovski, D.2    Moate, P.J.3    Sumner, A.E.4    Watanabe, R.M.5    Bergman, R.N.6
  • 14
    • 0023245416 scopus 로고
    • Estimation of endogenous glucose production during hyperinsulinemiceuglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates
    • Finegood DT, Bergman RN, Vranic M: Estimation of endogenous glucose production during hyperinsulinemiceuglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates. Diabetes 1987;36: 914-924.
    • (1987) Diabetes , vol.36 , pp. 914-924
    • Finegood, D.T.1    Bergman, R.N.2    Vranic, M.3
  • 16
    • 0018757294 scopus 로고
    • Role of glucagon, catecholamines, and growth hormone in human glucose counterregulation. Effects of somatostatin and combined alpha- and beta-adrenergic blockade on plasma glucose recovery and glucose flux rates after insulin-induced hypoglycemia
    • Rizza RA, Cryer PE, Gerich JE: Role of glucagon, catecholamines, and growth hormone in human glucose counterregulation. Effects of somatostatin and combined alpha- and beta-adrenergic blockade on plasma glucose recovery and glucose flux rates after insulin-induced hypoglycemia. J Clin Invest 1979;64:62-71.
    • (1979) J Clin Invest , vol.64 , pp. 62-71
    • Rizza, R.A.1    Cryer, P.E.2    Gerich, J.E.3
  • 17
    • 80155124676 scopus 로고    scopus 로고
    • Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: A randomized, 52-week, double-blind, active-controlled noninferiority trial
    • Nauck MA, del PS, Meier JJ, Duran-Garcia S, Rohwedder K, Elze M, Parikh SJ: Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: a randomized, 52-week, double-blind, active-controlled noninferiority trial. Diabetes Care 2011;34:2015-2022.
    • (2011) Diabetes Care , vol.34 , pp. 2015-2022
    • Nauck, M.A.1    Del Meier, P.S.J.J.2    Duran-Garcia, S.3    Rohwedder, K.4    Elze, M.5    Parikh, S.J.6
  • 18
    • 33644850953 scopus 로고    scopus 로고
    • Obesity and cardiovascular disease: Pathophysiology evaluation and effect of weight loss: An update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism
    • Poirier P, Giles TD, Bray GA, Hong Y, Stern JS, Pi-Sunyer FX, Eckel RH: Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation 2006;113:898-918.
    • (2006) Circulation , vol.113 , pp. 898-918
    • Poirier, P.1    Giles, T.D.2    Bray, G.A.3    Hong, Y.4    Stern, J.S.5    Pi-Sunyer, F.X.6    Eckel, R.H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.