Randomized Clinical Trial Comparing Efficacy of Simo Decoction and Acupuncture or Chewing Gum Alone on Postoperative Ileus in Patients with Hepatocellular Carcinoma after Hepatectomy

Medicine (United States)

Volumn 94, Issue 45, 2015, Pages e1968-

  You, Xue Mei ^a,b   Mo, Xin Shao ^a,b   Ma, Liang ^a,b   Zhong, Jian Hong ^a,b   Qin, Hong Gui ^a,b   Lu, Zhan ^a,b   Xiang, Bang De ^a,b   Wu, Fei Xiang ^a,b   Zhao, Xin Hua ^a,b   Tang, Juan ^a,b   Pang, Yong Hui ^a,b   Chen, Jie ^a,b   Li, Le Qun ^a,b  

^a GUANGXI MEDICAL UNIVERSITY   (China)

^b Guangxi Liver Cancer Diagnosis and Treatment Engineering and Technology Research Center   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHINESE DRUG; SIMO DECOCTION; UNCLASSIFIED DRUG; CHEWING GUM; HERBACEOUS AGENT; SIMO;

ACUPUNCTURE; ADULT; AGED; ARTICLE; CANCER SURGERY; CHEWING GUM; CHINA; CHINESE MEDICINE; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; EVIDENCE BASED PRACTICE; FEMALE; FEVER; FLATULENCE; HUMAN; HYDROTHORAX; INTESTINE FUNCTION; LENGTH OF STAY; LIVER CELL CARCINOMA; LIVER FAILURE; LIVER HEMORRHAGE; LIVER RESECTION; MAJOR CLINICAL STUDY; MALE; OPERATIVE BLOOD LOSS; PERISTALSIS; POSTOPERATIVE CARE; POSTOPERATIVE ILEUS; POSTOPERATIVE PAIN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STOMACH DISTENSION; ADVERSE EFFECTS; COMPARATIVE STUDY; ILEUS; INCIDENCE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS;

ACUPUNCTURE THERAPY; ADULT; AGED; CHEWING GUM; CHINA; DRUGS, CHINESE HERBAL; FEMALE; HEPATECTOMY; HUMANS; ILEUS; INCIDENCE; LENGTH OF STAY; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS;

EID: 84958168427     PISSN: 00257974     EISSN: 15365964     Source Type: Journal    
DOI: 10.1097/MD.0000000000001968     Document Type: Article

References (36)

1. Zhong JH, Ke Y, Wang YY, et al. Liver resection for patients with hepatocellular carcinoma and macrovascular invasion, multiple tumours, or portal hypertension. Gut. 2015;64:520-521.
2. Zhong JH, Rodriguez AC, Ke Y, et al. Hepatic resection as a safe and effective treatment for hepatocellular carcinoma involving a single large tumor, multiple tumors, or macrovascular invasion. Medicine (Baltimore). 2015;94:e396.
3. Zhong JH, Ke Y, Gong WF, et al. Hepatic resection associated with good survival for selected patients with intermediate and advancedstage hepatocellular carcinoma. Ann Surg. 2014;260:329-340.
4. Noble EJ, Harris R, Hosie KB, et al. Gum chewing reduces postoperative ileus? A systematic review and meta-analysis. Int J Surg. 2009;7:100-105.
5. Ho YM, Smith SR, Pockney P, et al. A meta-analysis on the effect of sham feeding following colectomy: should gum chewing be included in enhanced recovery after surgery protocols? Dis Colon Rectum. 2014;57:115-126.
6. Marwah S, Singla S, Tinna P. Role of gum chewing on the duration of postoperative ileus following ileostomy closure done for typhoid ileal perforation: a prospective randomized trial. Saudi J Gastroenterol. 2012;18:111-117.
7. Gan TJ, Robinson SB, Oderda GM, et al. Impact of postsurgical opioid use and ileus on economic outcomes in gastrointestinal surgeries. Curr Med Res Opin. 2015;31:677-686.
8. Koo KC, Yoon YE, Chung BH, et al. Analgesic opioid dose is an important indicator of postoperative ileus following radical cystectomy with ileal conduit: experience in the robotic surgery era. Yonsei Med J. 2014;55:1359-1365.
9. Chong T, Jin HB, Zhang JD, et al. [Clinical effects of the treatment of gastrointestinal dysfunction after stable thoracolumbar fractures with Simo decoction oral liquid]. Zhongguo Gu Shang. 2010;23: 595-597.
10. Wang M, Gao YH, Xu J, et al. Zusanli (ST36) acupoint injection for preventing postoperative ileus: a systematic review and metaanalysis of randomized clinical trials. Complement Ther Med. 2015;23:469-483.
11. van den Heijkant TC, Costes LM, van der Lee DG, et al. Randomized clinical trial of the effect of gum chewing on postoperative ileus and inflammation in colorectal surgery. Br J Surg. 2015;102:202-211.
12. Ertas IE, Gungorduk K, Ozdemir A, et al. Influence of gum chewing on postoperative bowel activity after complete staging surgery for gynecological malignancies: a randomized controlled trial. Gynecol Oncol. 2013;131:118-122.
13. Jakkaew B, Charoenkwan K. Effects of gum chewing on recovery of bowel function following cesarean section: a randomized controlled trial. Arch Gynecol Obstet. 2013;288:255-260.
14. Zhong JH, You XM, Lu SD, et al. Historical comparison of overall survival after hepatic resection for patients with large and/or multinodular hepatocellular carcinoma. Medicine (Baltimore). 2015;94:e1426.
15. Zhong JH, Xiang BD, Gong WF, et al. Comparison of long-term survival of patients with BCLC stage B hepatocellular carcinoma after liver resection or transarterial chemoembolization. PLoS ONE. 2013;8:e68193.
16. Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205-213.
17. Pang YH, Ma L, Mao CL, et al. Influence of acupoint therapy with simo decoction on postoperative gastrointestinal function recovery of primary liver cancer patients. J Nurs (China). 2013;20 (3A):53-55.
18. Trotti A, Colevas AD, Setser A, et al. CTCAE v3.0: development of a comprehensive grading system for the adverse effects of cancer treatment. Semin Radiat Oncol. 2003;13:176-181.
19. Barletta JF, Senagore AJ. Reducing the burden of postoperative ileus: evaluating and implementing an evidence-based strategy. World J Surg. 2014;38:1966-1977.
20. van Bree SH, Nemethova A, Cailotto C, et al. New therapeutic strategies for postoperative ileus. Nat Rev Gastroenterol Hepatol. 2012;9:675-683.
21. Li S, Liu Y, Peng Q, et al. Chewing gum reduces postoperative ileus following abdominal surgery: a meta-analysis of 17 randomized controlled trials. J Gastroenterol Hepatol. 2013;28:1122-1132.
22. Jang SY, Ju EY, Kim DE, et al. First flatus time and xerostomia associated with gum-chewing after liver resection. J Clin Nurs. 2012;21:2188-2192.
23. Meng ZQ, Garcia MK, Chiang JS, et al. Electro-acupuncture to prevent prolonged postoperative ileus: a randomized clinical trial. World J Gastroenterol. 2010;16:104-111.
24. Stoffels B, Hupa KJ, Snoek SA, et al. Postoperative ileus involves interleukin-1 receptor signaling in enteric glia. Gastroenterology. 2014;146:176.e1-187.e1.
25. The FO, Bennink RJ, Ankum WM, et al. Intestinal handling-induced mast cell activation and inflammation in human postoperative ileus. Gut. 2008;57:33-40.
26. Engel DR, Koscielny A, Wehner S, et al. T helper type 1 memory cells disseminate postoperative ileus over the entire intestinal tract. Nat Med. 2010;16:1407-1413.
27. van Bree SH, Gomez-Pinilla PJ, van de Bovenkamp FS, et al. Inhibition of spleen tyrosine kinase as treatment of postoperative ileus. Gut. 2013;62:1581-1590.
28. Lubbers T, Luyer MD, de Haan JJ, et al. Lipid-rich enteral nutrition reduces postoperative ileus in rats via activation of cholecystokininreceptors. Ann Surg. 2009;249:481-487.
29. The F, Cailotto C, van der Vliet J, et al. Central activation of the cholinergic anti-inflammatory pathway reduces surgical inflammation in experimental post-operative ileus. Br J Pharmacol. 2011;163:1007-1016.
30. Luyer MD, Greve JW, Hadfoune M, et al. Nutritional stimulation of cholecystokinin receptors inhibits inflammation via the vagus nerve. J Exp Med. 2005;202:1023-1029.
31. Stern RM, Crawford HE, Stewart WR, et al. Sham feeding. Cephalic-vagal influences on gastric myoelectric activity. Dig Dis Sci. 1989;34:521-527.
32. Wang CX, Hou LB, Liu ST. Effect of Changtong oral liquid on serum cytokine concentrations in rats with postoperative intestinal adhesion. Di Yi Jun Yi Da Xue Xue Bao. 2005;25:601-604.
33. Wang CX, Hou LB, Ma Y. [Changtong oral liquid for prevention of postoperative intestinal adhesion: an experimental study]. Di Yi Jun Yi Da Xue Xue Bao. 2005;25:187-189200.
34. Dai C, Liu N, Chen W, et al. Simo decoction promotes contraction of antral circular smooth muscle mainly via muscarinic M3 receptor. J Ethnopharmacol. 2012;144:270-276.
35. Li Y, Tougas G, Chiverton SG, et al. The effect of acupuncture on gastrointestinal function and disorders. Am J Gastroenterol. 1992;87:1372-1381.
36. Ng SS, Leung WW, Mak TW, et al. Electroacupuncture reduces duration of postoperative ileus after laparoscopic surgery for colorectal cancer. Gastroenterology. 2013;144:307e1-313e1.