Predominance of synovial sensory nerve fibers in arthrofibrosis following total knee arthroplasty compared to osteoarthritis of the knee

Journal of Orthopaedic Surgery and Research

Volumn 11, Issue 1, 2016, Pages

  Koeck, Franz Xaver ^a   Schmitt, Miriam ^b   Baier, Clemens ^c   Stangl, Hubert ^b   Beckmann, Johannes ^d   Grifka, Joachim ^c   Straub, Rainer H ^b  

^a MedArtes Private Orthopaedic Clinic   (Germany)

^b UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^c UNIVERSITY OF REGENSBURG   (Germany)

^d SPORTKLINIK STUTTGART   (Germany)

Author keywords

Arthrofibrosis; Arthroplasty; Knee; Nerve fibers; Osteoarthritis

Indexed keywords

SUBSTANCE P;

ADVERSE EFFECTS; AGED; COMPARATIVE STUDY; FEMALE; FIBROSIS; HUMAN; INNERVATION; KNEE; KNEE OSTEOARTHRITIS; KNEE REPLACEMENT; MALE; METABOLISM; MIDDLE AGED; NERVE FIBER; PAIN RECEPTOR; PATHOLOGY; SEVERITY OF ILLNESS INDEX; SYNOVIUM; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ARTHROPLASTY, REPLACEMENT, KNEE; FEMALE; FIBROSIS; HUMANS; KNEE JOINT; MALE; MIDDLE AGED; NERVE FIBERS; NOCICEPTORS; OSTEOARTHRITIS, KNEE; SEVERITY OF ILLNESS INDEX; SUBSTANCE P; SYNOVIAL MEMBRANE;

EID: 84958155189     PISSN: None     EISSN: 1749799X     Source Type: Journal    
DOI: 10.1186/s13018-016-0359-0     Document Type: Article

References (42)

1. Ritter MA, Berend ME, Meding JB, et al. 2001. Long-term followup of anatomic graduated components posterior cruciate-retaining total knee replacement. Clin Orthop Relat Res. (388): 51-57
2. Sextro GS, Berry DJ, Rand JA. 2001. Total knee arthroplasty using cruciate-retaining kinematic condylar prosthesis. Clin Orthop Relat Res (388): 33-40
3. Mohtadi NG, Webster-Bogaert S, Fowler PJ. Limitation of motion following anterior cruciate ligament reconstruction. A case-control study. Am J Sports Med. 1991;19(6):620-4. discussion 624-5.
4. Boldt JG, Munzinger UK, Zanetti M, et al. Arthrofibrosis associated with total knee arthroplasty: gray-scale and power Doppler sonographic findings. AJR Am J Roentgenol. 2004;182(2):337-40. doi: 10.2214/ajr.182.2.1820337.
5. Ipach I, Mittag F, Lahrmann J, et al. Arthrofibrosis after TKA-influence factors on the absolute flexion and gain in flexion after manipulation under anaesthesia. BMC Musculoskelet Disord. 2011;12:184. doi: 10.1186/1471-2474-12-184.
6. Werner BC, Carr JB, Wiggins JC, et al. Manipulation under anesthesia after total knee arthroplasty is associated with an increased incidence of subsequent revision surgery. J Arthroplasty. 2015. doi: 10.1016/j.arth.2015.01.061.
7. Tjoumakaris FP, Tucker BC, Post Z, et al. Arthroscopic lysis of adhesions for the stiff total knee: results after failed manipulation. Orthopedics. 2014;37(5):e482-7. doi: 10.3928/01477447-20140430-60.
8. Ghani H, Maffulli N, Khanduja V. Management of stiffness following total knee arthroplasty: a systematic review. Knee. 2012;19(6):751-9. doi: 10.1016/j.knee.2012.02.010.
9. Sharkey PF, Lichstein PM, Shen C, et al. Why are total knee arthroplasties failing today-has anything changed after 10 years? J Arthroplasty. 2014;29(9):1774-8. doi: 10.1016/j.arth.2013.07.024.
10. Lavernia CJ, Villa JM, Iacobelli DA. What is the role of mental health in primary total knee arthroplasty? Clin Orthop Relat Res. 2015;473(1):159-63. doi: 10.1007/s11999-014-3769-5.
11. Zeichen J, van Griensven M, Albers I, et al. Immunohistochemical localization of collagen VI in arthrofibrosis. Arch Orthop Trauma Surg. 1999;119(5-6):315-8.
12. Unterhauser FN, Bosch U, Zeichen J, et al. Alpha-smooth muscle actin containing contractile fibroblastic cells in human knee arthrofibrosis tissue. Winner of the AGA-DonJoy Award 2003. Arch Orthop Trauma Surg. 2004;124(9):585-91. doi: 10.1007/s00402-004-0742-x.
13. Krenn V, Ruppert M, Knöß P, et al. Synovialitis vom arthrofibrotischen Typ: Kriterien eines neuen Synovialitis-Typus für die Diagnose der Arthrofibrose (Synovialitis of the arthrofibrotic type: criteria of a new synovialitis type for the diagnosis of arthrofibrosis). Z Rheumatol. 2013;72(3):270-8. doi: 10.1007/s00393-012-1076-7.
14. Freeman TA, Parvizi J, Della Valle CJ, et al. Reactive oxygen and nitrogen species induce protein and DNA modifications driving arthrofibrosis following total knee arthroplasty. Fibrogenesis Tissue Repair. 2009;2(1):5. doi: 10.1186/1755-1536-2-5.
15. Pfitzner T, Geissler S, Duda G, et al. Increased BMP expression in arthrofibrosis after TKA. Knee Surg Sports Traumatol Arthrosc. 2012;20(9):1803-8. doi: 10.1007/s00167-011-1774-8.
16. Brown CA, Toth AP, Magnussen B. Clinical benefits of intra-articular anakinra for arthrofibrosis. Orthopedics. 2010;33(12):877. doi: 10.3928/01477447-20101021-09.
17. Bosch U, Zeichen J, Skutek M, et al. Arthrofibrosis is the result of a T cell mediated immune response. Knee Surg Sports Traumatol Arthrosc. 2001;9(5):282-9. doi: 10.1007/s001670100218.
18. Freeman TA, Parvizi J, Dela Valle CJ, et al. Mast cells and hypoxia drive tissue metaplasia and heterotopic ossification in idiopathic arthrofibrosis after total knee arthroplasty. Fibrogenesis Tissue Repair. 2010;3:17. doi: 10.1186/1755-1536-3-17.
19. Emami MJ, Jaberi FM, Azarpira N, et al. Prevention of arthrofibrosis by monoclonal antibody against vascular endothelial growth factor: a novel use of bevacizumab in rabbits. Orthop Traumatol Surg Res. 2012;98(7):759-64. doi: 10.1016/j.otsr.2012.05.020.
20. Watson RS, Gouze E, Levings PP, et al. Gene delivery of TGF-β1 induces arthrofibrosis and chondrometaplasia of synovium in vivo. Lab Invest. 2010;90(11):1615-27. doi: 10.1038/labinvest.2010.145.
21. Basbaum AI, Bautista DM, Scherrer G, et al. Cellular and molecular mechanisms of pain. Cell. 2009;139(2):267-84. doi: 10.1016/j.cell.2009.09.028.
22. Bellamy N, Buchanan WW, Goldsmith CH, et al. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol. 1988;15(12):1833-40.
23. Insall JN, Dorr LD, Scott RD, et al. 1989. Rationale of the Knee Society clinical rating system. Clin Orthop Relat Res. (248): 13-14
24. Roos EM, Roos HP, Lohmander LS, et al. Knee Injury and Osteoarthritis Outcome Score (KOOS)-development of a self-administered outcome measure. J Orthop Sports Phys Ther. 1998;28(2):88-96. doi: 10.2519/jospt.1998.28.2.88.
25. Weidler C, Holzer C, Harbuz M, et al. Low density of sympathetic nerve fibres and increased density of brain derived neurotrophic factor positive cells in RA synovium. Ann Rheum Dis. 2005;64(1):13-20. doi: 10.1136/ard.2003.016154.
26. Miller LE, Grifka J, Schölmerich J, et al. Norepinephrine from synovial tyrosine hydroxylase positive cells is a strong indicator of synovial inflammation in rheumatoid arthritis. J Rheumatol. 2002;29(3):427-35.
27. Lehner B, Koeck FX, Capellino S, et al. Preponderance of sensory versus sympathetic nerve fibers and increased cellularity in the infrapatellar fat pad in anterior knee pain patients after primary arthroplasty. J Orthop Res. 2008;26(3):342-50. doi: 10.1002/jor.20498.
28. Beckmann J, Knödl M, Bauser E, et al. Loss of sympathetic nerve fibers in vital intertrochanteric bone cylinders lateral to osteonecrosis of the femoral head. Joint Bone Spine. 2013;80(2):188-94. doi: 10.1016/j.jbspin.2012.03.003.
29. Haas S, Capellino S, Phan NQ, et al. Low density of sympathetic nerve fibers relative to substance P-positive nerve fibers in lesional skin of chronic pruritus and prurigo nodularis. J Dermatol Sci. 2010;58(3):193-7. doi: 10.1016/j.jdermsci.2010.03.020.
30. Koeck F, Bobrik V, Fassold A, et al. Marked loss of sympathetic nerve fibers in chronic Charcot foot of diabetic origin compared to ankle joint osteoarthritis. J Orthop Res. 2009;27(6):736-41. doi: 10.1002/jor.20807.
31. Schubert TEO, Weidler C, Lerch K, et al. Achilles tendinosis is associated with sprouting of substance P positive nerve fibres. Ann Rheum Dis. 2005;64(7):1083-6. doi: 10.1136/ard.2004.029876.
32. Schubert TEO, Weidler C, Borisch N, et al. Dupuytren's contracture is associated with sprouting of substance P positive nerve fibres and infiltration by mast cells. Ann Rheum Dis. 2006;65(3):414-5. doi: 10.1136/ard.2005.044016.
33. Aloe L, Tuveri MA, Carcassi U, et al. Nerve growth factor in the synovial fluid of patients with chronic arthritis. Arthritis Rheum. 1992;35(3):351-5.
34. Stead RH, Dixon MF, Bramwell NH, et al. Mast cells are closely apposed to nerves in the human gastrointestinal mucosa. Gastroenterology. 1989;97(3):575-85.
35. Burssens P, Steyaert A, Forsyth R, et al. Exogenously administered substance P and neutral endopeptidase inhibitors stimulate fibroblast proliferation, angiogenesis and collagen organization during Achilles tendon healing. Foot Ankle Int. 2005;26(10):832-9.
36. Lotz M, Vaughan JH, Carson DA. Effect of neuropeptides on production of inflammatory cytokines by human monocytes. Science. 1988;241(4870):1218-21.
37. Konttinen YT, Kemppinen P, Segerberg M, et al. Peripheral and spinal neural mechanisms in arthritis, with particular reference to treatment of inflammation and pain. Arthritis Rheum. 1994;37(7):965-82.
38. Katayama I, Nishioka K. Substance P augments fibrogenic cytokine-induced fibroblast proliferation: possible involvement of neuropeptide in tissue fibrosis. J Dermatol Sci. 1997;15(3):201-6.
39. Lieb K, Fiebich BL, Berger M, et al. The neuropeptide substance P activates transcription factor NF-kappa B and kappa B-dependent gene expression in human astrocytoma cells. J Immunol. 1997;159(10):4952-8.
40. Lai X, Wang Z, Zhu J, et al. Effect of substance P on gene expression of transforming growth factor beta-1 and its receptors in rat's fibroblasts. Chin J Traumatol. 2003;6(6):350-4.
41. Beinborn M, Blum A, Hang L, et al. TGF-beta regulates T-cell neurokinin-1 receptor internalization and function. Proc Natl Acad Sci USA. 2010;107(9):4293-8. doi: 10.1073/pnas.0905877107.
42. Monument MJ, Hart DA, Befus AD, et al. The mast cell stabilizer ketotifen reduces joint capsule fibrosis in a rabbit model of post-traumatic joint contractures. Inflamm Res. 2012;61(4):285-92. doi: 10.1007/s00011-011-0409-3.